Santee Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to ₩234,741 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Find the Best Santee Vacation Packages

Santee Hotel Deals

Lewis and Clark Resort

Lewis and Clark Resort

2.5 out of 5
43496 Shore Drive, Yankton, SD
The price is ₩167,394 per night from Jul 27 to Jul 28
₩167,394
₩176,926 total
Jul 27 - Jul 28
includes taxes & fees
8.6/10 Excellent! (228 reviews)
"Beautiful place, rooms are very outdated but at least clean. Very friendly staff and beautiful beaches"

Reviewed on Jul 3, 2025

Lewis and Clark Resort
2 Mi to Lewis and Clark Lake: Spacious Getaway

2 Mi to Lewis and Clark Lake: Spacious Getaway

3 out of 5
Crofton
Get rates
2 Mi to Lewis and Clark Lake: Spacious Getaway
Scenic Yankton Retreat w/ Fire Pit: 1 Mi to Lake!

Scenic Yankton Retreat w/ Fire Pit: 1 Mi to Lake!

3 out of 5
Yankton
Get rates
Scenic Yankton Retreat w/ Fire Pit: 1 Mi to Lake!
See all 59 properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santee vacation package cost?
You'll find cheap prices on Expedia for your Santee break. However, factors like the length of stay, hotel choice and season will influence how much your vacation to Santee costs.
What are the cheapest months to go to Santee?
If you're looking to snag a cheap Santee vacation package, consider traveling in January, February and November. You'll usually find lower rates on flights and accommodations during these months — ideal for a budget-friendly getaway.
How many days is enough for Santee?
Typically, a handful of days is enough to explore the main sights during your Santee vacation. But if you prefer to have some time to kick back or go on day tours, think about extending your trip.
How to find the best Santee package deals?
Start your search for a Santee package deal by entering your preferred trip dates and destination under our "Packages" tab. Then select some filters, like "Property type" and "Popular locations," to fine-tune the results to your exact style. You can also sort by "Package discount" and discover offers that come with unbeatable savings. If you don't find the ideal Santee package deal right away, just tweak your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santee escape off to a flying start.
Is it cheaper to book a Santee vacation as a package?
An Expedia vacation package could land you significant savings when compared to booking hotels and flights separately. Better still, you can customize your Santee trip to fit your exact needs. Pick your preferred flight time, select the hotel type and add a rental car. Browse our great deals to see how much you can save.
When to book a vacation package to Santee?
If you have your Santee vacation dates confirmed, book as soon as you can to snap up some awesome deals. With Expedia, you can typically reserve some flights up to one year in advance. Prefer spontaneous getaways? Our last-minute deals are great for impromptu escapes.
How to plan a trip to Santee?

  1. Choose when to travel: Check your schedule and get packing. Your preferred time of year and the type of activities available will also help you decide when to escape to Santee.
  2. Plan your budget wisely: On top of the cost of your stay, you should consider other expenses too. These include transportation, flights and food. Also, put aside a little extra for unexpected costs that may crop up during your trip to Santee.
  3. Decide how many days away: Start by compiling a list of the activities and attractions you want to get to in Santee. Then, estimate how long you'll need for each, along with any travel time.
  4. Combine your flights and hotel: Epic destination, check. Length of stay, check. Now all that's left is to find a Santee vacation package that brings all your bookings together.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.