We highly recommend this hotel. It's in a good location; an easy walk to Pub Street and a few small bars even closer. The immediate area is interesting, but safe.
As for the hotel itself, it has everything you could ask for in a boutique hotel, and then some. We've stayed in a a few hotels that were more luxurious, but not many. And the service is literally the best we've ever had at a hotel, far exceeding even that of high-end luxury hotel chains that pride themselves on their level of service. The staff is super helpful, and bends over backward to help you arrange transportation, tours, and entertainment. Even though we only stayed for two nights, everyone went out of their way to get to know us, and by the time we left we felt like we were saying goodbye to family.
We really wish we could have stayed longer, and if we ever return to Siem Reap, we will definitely be staying there.