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Our top choices for Santa Clara hotels

Outdoor pool, open 7:00 AM to 10:30 PM, free cabanas, pool umbrellas
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
Tocumen
8.6 out of 10, Excellent, (1843)
"Better than expected: Location, transportation to and from airport, pool area tropical and comfortable. "
United States
Marty
The price is ₩178,782
₩196,660 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Riande Aeropuerto Hotel & Casino
Outdoor pool, sun loungers
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (4747)
"The rooms were nice and the food was great..great staff!!"
United States
Tffany
The price is ₩175,075
₩192,583 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Hotel Riu Plaza Panama
Suite, 1 Bedroom, Golf View (Terrace) | Premium bedding, minibar, in-room safe, desk
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (644)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is ₩312,040
₩343,244 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Breakfast, lunch, dinner served; international cuisine
Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
Cerro Viento
8.8 out of 10, Excellent, (1008)
"Location Location Location! Clean, safe, beautiful. Loved it!"
United States
Sharon Gobern Dorray and Jason
The price is ₩156,764
₩172,440 total
includes taxes & fees
Jan 31 - Feb 1, 2026
Courtyard by Marriott Panama Metromall
2 outdoor pools, pool umbrellas, sun loungers
Radisson Hotel Panama Canal

Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador
8.4 out of 10, Very Good, (1002)
"Unbeatable location if your visit is all about the Panama Canal. "
United States
Vitaliy
The price is ₩112,579
₩123,837 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Radisson Hotel Panama Canal
View from property
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2152)
"Great location of the hotel with a lovely breakfast and friendly staff"
United States
fouad
The price is ₩226,050
₩248,655 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Plaza Paitilla Inn Hotel
50-inch LED TV with satellite channels
Arcadia Condo Suites

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (177)
"Was a great buy. Beautiful views and spacious rooms. Great amenities. "
United States
Lesley
The price is ₩118,378
₩196,268 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Arcadia Condo Suites
Lobby
The Executive Hotel

The Executive Hotel

The Executive Hotel
3.5 star property
Bella Vista
9.2 out of 10, Wonderful, (1014)
"A nice hotel to stay great location"
United States
angela
The Executive Hotel
Terrace/patio
Sheraton Grand Panama

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1002)
"Was amazing food was delicious and stay was great "
United States
Amanda
The price is ₩191,720
₩210,892 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Sheraton Grand Panama
4 outdoor pools, free cabanas, pool umbrellas
JW Marriott Panama

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1005)
"Bedroom was very comfy, also the staff were very on point. I will definitely recommend this hotel and there services, there is so much to do at this hotel."
United States
Sarran
The price is ₩384,584
₩423,042 total
includes taxes & fees
Jan 30 - Jan 31, 2026
JW Marriott Panama
Outdoor pool, pool umbrellas, sun loungers
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1132)
"The room was clean and the location was great."
United States
Wendy
The price is ₩157,979
₩173,777 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Ramada Plaza by Wyndham Panama Punta Pacifica
View from room
The Beach House

The Beach House

The Beach House
3.0 star property
Amador
8.4 out of 10, Very Good, (411)
"Fantastic location on Amador Causeway and access to paddleboarding, restaurants, nightlife and family friendly events. One cool sloth in the tree overhanging the walkway at the Culebra nature area right by the prroperty."
United States
Cynthia
The Beach House
Restaurant
Hyatt Regency Panama City

Hyatt Regency Panama City

Hyatt Regency Panama City
4.5 star property
Bella Vista
10.0 out of 10, Exceptional, (146)
"Breakfast was so good , hotel was clean "
United States
ankit
The price is ₩224,102
₩246,512 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hyatt Regency Panama City
40-inch Smart TV with cable channels, TV
Renaissance Panama City Hotel

Renaissance Panama City Hotel

Renaissance Panama City Hotel
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (102)
"I stayed for nine nights and I enjoyed my time at this hotel I recommend this hotel for several days staff is nice and the hotel is worth it. "
United States
Sharon Isoken
The price is ₩157,855
₩173,641 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Renaissance Panama City Hotel
3 outdoor pools, pool umbrellas, sun loungers
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
Veracruz
8.0 out of 10, Very Good, (1004)
"Beautiful property and amazing staff"
United States
CARMEN
The price is ₩338,434
₩372,278 total
includes taxes & fees
Jan 30 - Jan 31, 2026
The Westin Playa Bonita Panama
Outdoor pool
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (631)
"Location is just ok as well as the breakfast."
Canada
john
The price is ₩104,838
₩155,684 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Waymore Hotel Spa & Casino
Terrace/patio
Marriott Panama Hotel

Marriott Panama Hotel

Marriott Panama Hotel
4.0 star property
Panama City
9.0 out of 10, Wonderful, (1005)
"Great hotel and staff!"
United States
Catherine
The price is ₩217,311
₩239,042 total
includes taxes & fees
Jan 30 - Jan 31, 2026
Marriott Panama Hotel
Exterior
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (568)
"Amazing hotel , location , staff and amenities . Clean, elegant , great service. "
United States
Nicole
The price is ₩510,396
₩561,436 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Sofitel Legend Casco Viejo, Panama City
Exterior
Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
3.0 star property
San Francisco
The price is ₩276,643
₩304,307 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Dovle Residences by HMS-Preferred Member
Exterior
Hotel Milan

Hotel Milan

Hotel Milan
3.0 star property
Bella Vista
9.0 out of 10, Wonderful, (434)
"It was a very pleasant experience the hotel is located in a great neighborhood, staff were friendly and competent, secure property and parking, clean and decent accommodations, especially at the room price point. "
Canada
Roger
The price is ₩57,187
₩62,906 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hotel Milan
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Santa Clara attractions

Culebra Cut

You can find out about the history of Santa Clara with a visit to Culebra Cut. Check out the casinos and top-notch restaurants in this walkable area.
See properties

Learn more about Santa Clara

Santa Clara awaits: its natural setting, monuments, history, and more!

See all hotels in Santa Clara
Adobe

Top Santa Clara Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"It was a great stay! Staff were great but could be more friendlier. The only recommendation we have is for rooms to have shower cap. "
Farah 5-night trip
Posted 13 hours ago
Hotel Riu Plaza Panama

More cheap stays in Santa Clara

Panama House Bed & Breakfast

Panama House Bed & Breakfast

Calle 1era El Carmen- Casa # 32 Panama City
The price is ₩59,060 per night from Jan 5 to Jan 6
₩59,060
₩64,966 total
Jan 5 - Jan 6, 2026
includes taxes & fees
8.8/10 Excellent! (185 reviews)

Frequently asked questions

What's the best place for a stay in Santa Clara?
Located 15.8 mi (25.5 km) from the heart of Santa Clara, Hotel Riu Plaza Panama is a top choice for your stay based on our traveler data. Two other choices for your stay in the area are Megapolis Hotel Panamá and Las Americas Golden Tower Panama. See all available top hotels, or vacation rentals in Santa Clara.
If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable if cancelled before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Clara.
Where can I learn more about changing or cancelling my trip to Santa Clara?
To access more information about rescheduling or cancelling your trip to Santa Clara, go to https://www.expedia.com/service/.
What's the best place to stay near Culebra Cut?
Gamboa Rainforest Reserve is one of the top choices for your stay based on our traveler data, and this 3.5-star hotel offers a marina and a full-service spa. It's located 2.9 mi (4.7 km) from Culebra Cut. Other good options within 5 miles include Canopy Bed & Breakfast and Casa en Gamboa al lado Canal de Panama.
What is staying in Santa Clara like?
Visitors can enjoy all that Santa Clara has to offer including its monuments. A top sight in the area is Albrook Shopping Mall. There are 1681 hotels and other accommodations in the surrounding area. Find out more about Santa Clara.
What is there to see in Santa Clara?
A favorite place to visit is Culebra Cut. Additionally, you'll find Albrook Shopping Mall in the area. Check out what more to see and do in Expedia's Santa Clara guide.
What's the seasonal weather like in Santa Clara?
The hottest months are usually April and March with an average temp of 79°F, while the coldest months are January and February with an average of 78°F. The rainiest months in Santa Clara are July, August, November, and October, with each month seeing an average of 11 inches of rainfall.

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