Find hotels in Clayton, St. Louis from ₩140,371

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Our top choices for Clayton hotels

Exterior
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
Clayton
8.8 out of 10, Excellent, (3032)
"Clean room, good breakfast and good location "
United States
Martin
The price is ₩132,873
₩155,112 total
includes taxes & fees
Dec 21 - Dec 22
Clayton Plaza Hotel & Extended Stay
2 bars/lounges, rooftop bar
AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton
3.0 star property
Clayton
9.0 out of 10, Wonderful, (223)
"Enjoyed my stay"
United States
Kingsley
The price is ₩180,281
₩210,456 total
includes taxes & fees
Dec 21 - Dec 22
AC Hotel St. Louis Clayton
Outdoor pool, open 8:00 AM to 8:30 PM, pool umbrellas, sun loungers
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Clayton
8.8 out of 10, Excellent, (676)
"Small rooms but beautiful lobby. "
United States
Debbie
The price is ₩176,143
₩207,387 total
includes taxes & fees
Dec 19 - Dec 20
Le Méridien St. Louis Clayton
Meeting facility
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Clayton
9.2 out of 10, Wonderful, (553)
"Service is exceptional!!!"
United States
Jorge
The price is ₩737,377
₩860,795 total
includes taxes & fees
Dec 21 - Dec 22
The Ritz-Carlton, St. Louis
Outdoor dining
Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
3.0 star property
Clayton
9.0 out of 10, Wonderful, (911)
"Clean, nice staff, hot breakfast with variety of options"
United States
Tamara
The price is ₩164,322
₩193,469 total
includes taxes & fees
Dec 20 - Dec 21
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
View from property
Residence Inn By Marriott St. Louis Clayton

Residence Inn By Marriott St. Louis Clayton

Residence Inn By Marriott St. Louis Clayton
3.0 star property
Clayton
9.2 out of 10, Wonderful, (193)
"Clean large rooms,comfortable beds"
United States
RAGHAV
The price is ₩224,612
₩270,073 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Residence Inn By Marriott St. Louis Clayton
Property entrance
Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Seven Gables, St. Louis West, a Tribute Portfolio Hotel
3.5 star property
Clayton
8.4 out of 10, Very Good, (577)
"Love this place."
United States
Robert
The price is ₩180,281
₩224,450 total
includes taxes & fees
Dec 19 - Dec 20
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Exterior
Homewood Suites by Hilton St Louis - Galleria

Homewood Suites by Hilton St Louis - Galleria

Homewood Suites by Hilton St Louis - Galleria
3.0 star property
Clayton
8.0 out of 10, Very Good, (1003)
"The rooms were clean and comfortable."
United States
Kelly
The price is ₩176,143
₩209,148 total
includes taxes & fees
Dec 21 - Dec 22
Homewood Suites by Hilton St Louis - Galleria
Daily cooked-to-order breakfast for a fee
River City Casino & Hotel

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
13.6 km from Clayton
9.0 out of 10, Wonderful, (1447)
"Awesome place to stay!!"
United States
Kaitlyn
The price is ₩130,024
₩172,804 total
includes taxes & fees
Dec 15 - Dec 16
River City Casino & Hotel
Free daily buffet breakfast
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
20.1 km from Clayton
9.4 out of 10, Exceptional, (1005)
"The staff were awesome "
United States
Corey
The price is ₩164,912
₩189,527 total
includes taxes & fees
Dec 21 - Dec 22
Country Inn & Suites by Radisson, St. Charles Historic District
Exterior
Moonrise Hotel

Moonrise Hotel

Moonrise Hotel
4.0 star property
2.6 km from Clayton
9.0 out of 10, Wonderful, (1915)
"Great service, unique hotel. Would absolutely stay again!"
United States
Michael
The price is ₩174,384
₩207,394 total
includes taxes & fees
Dec 15 - Dec 16
Moonrise Hotel
Lobby
Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
3.0 star property
20 km from Clayton
9.6 out of 10, Exceptional, (1003)
"The stay was perfect. Very clean, quiet and comfortable. The staff were very friendly and helpful. I will stay again. "
United States
holly
The price is ₩169,922
₩196,979 total
includes taxes & fees
Dec 21 - Dec 22
Drury Plaza Hotel St. Louis St. Charles
Suite, 1 King Bed, Non Smoking, Refrigerator & Microwave | Premium bedding, pillowtop beds, in-room safe, desk
Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel
3.0 star property
20.5 km from Clayton
8.0 out of 10, Very Good, (1005)
"It was perfect, and the staff were very helpful!"
United States
Susan
The price is ₩124,349
₩144,153 total
includes taxes & fees
Dec 18 - Dec 19
Best Western Plus The Charles Hotel
Lobby
Courtyard by Marriott St Louis Creve Coeur

Courtyard by Marriott St Louis Creve Coeur

Courtyard by Marriott St Louis Creve Coeur
3.0 star property
Creve Coeur, 10.9 km from Clayton
8.8 out of 10, Excellent, (1003)
"Clean room and very helpful staff"
United States
Amy
The price is ₩180,281
₩209,555 total
includes taxes & fees
Dec 21 - Dec 22
Courtyard by Marriott St Louis Creve Coeur
Lobby
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 12 km from Clayton
8.4 out of 10, Very Good, (4009)
"Arch view room is big and comfortable fantastic. . "
United States
Tim
The price is ₩124,349
₩146,644 total
includes taxes & fees
Dec 27 - Dec 28
Hyatt Regency St. Louis at The Arch
Courtyard
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
3.0 star property
17.2 km from Clayton
7.4 out of 10, Good, (1001)
"Clean lobby, super friendly staff, effortless check in. There’s even a small market with food and essentials right next to the check in desk. "
United States
Jen
The price is ₩94,692
₩109,832 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Exterior
Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
20.3 km from Clayton
8.4 out of 10, Very Good, (1003)
"Nice staff at reception. "
United States
Denise
The price is ₩113,133
₩130,021 total
includes taxes & fees
Dec 21 - Dec 22
Comfort Suites St Charles - St Louis
Casino
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
19.8 km from Clayton
8.4 out of 10, Very Good, (1004)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is ₩224,833
₩287,273 total
includes taxes & fees
Dec 15 - Dec 16
Ameristar Casino Resort and Spa
Front of property - evening/night
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis
3.5 star property
18.3 km from Clayton
8.4 out of 10, Very Good, (2219)
"Front staff was very friendly and very helpful. Check-in and check out was smooth and very easy. "
United States
James
The price is ₩155,145
₩202,462 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Hollywood Casino & Hotel St. Louis
Lobby
Country Inn & Suites by Radisson, St. Peters, MO

Country Inn & Suites by Radisson, St. Peters, MO

Country Inn & Suites by Radisson, St. Peters, MO
2.5 star property
26.6 km from Clayton
8.2 out of 10, Very Good, (1001)
"This was an amazing stay"
United States
Madison
The price is ₩133,363
₩153,312 total
includes taxes & fees
Dec 21 - Dec 22
Country Inn & Suites by Radisson, St. Peters, MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Clayton

Find the best Clayton areas and neighborhoods for the activities you enjoy most.
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Central West End

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

St. Louis which includes interior views

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

Top Clayton Hotel Reviews

Live by Loews - St.Louis

Live by Loews - St.Louis

10/10 Excellent
"Yes I loved it I will be back for more stays!!"
Donald 1-night trip
Posted 4 days ago
Live by Loews - St.Louis

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Frequently asked questions

What's it like in Clayton?
Clayton is a welcoming neighborhood known for its array of dining options and sporting events. Be sure to check out Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center as part of your Clayton travel plans.
Where is the best hotel for a stay in Clayton?
Based on Expedia customer reviews, AC Hotel St. Louis Clayton is the highest ranked property in Clayton. This hotel offers 2 restaurants and 2 bars. Other top choices in the neighborhood include Residence Inn By Marriott St. Louis Clayton and The Ritz-Carlton, St. Louis.
How many hotels can I expect to find in Clayton?
Expedia has 9 Clayton hotels and other accommodations, and one might make a good home base for venturing out into the greater St. Louis area.
If I need to cancel my hotel reservation in Clayton, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to view the best options available in Clayton.
Where can I learn more about changing or cancelling my trip to Clayton?
To find more details about rescheduling or cancelling your trip to Clayton, click here.
What are the top things to see and do in Clayton?
A few attractions you might want to check out while you're in Clayton are Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. When you're sightseeing in St. Louis, Tao Tennis Center and Center of Creative Arts are also worth a stop.
How can I get around Clayton and the greater St. Louis area?
Ready to get out and explore the city? Clayton Station is the closest metro station.