What's it like in Clayton?

Clayton is a welcoming neighborhood known for its array of dining options and sporting events. Be sure to check out Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center as part of your Clayton travel plans.

Where is the best hotel for a stay in Clayton?

Based on our traveler data, Clayton Plaza Hotel & Extended Stay is one of the top choices for your stay in Clayton. This hotel offers free breakfast and an indoor pool. Other good choices for your stay in the neighborhood include AC Hotel St. Louis Clayton and Le Méridien St. Louis Clayton .

How many hotels can I expect to find in Clayton?

Expedia has 21 hotels and other accommodations in Clayton to choose from, making this an ideal home base for exploring the greater St. Louis area.

If I need to cancel my hotel reservation in Clayton, will I receive a refund?

Yes, you'll find most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to view the best options available in Clayton.

Where can I learn more about changing or cancelling my trip to Clayton?

To find more details about rescheduling or cancelling your trip to Clayton, click here .

What are the top things to see and do in Clayton?

A few attractions you might want to check out while you're in Clayton are Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. When you're sightseeing in St. Louis, St. Louis Zoo and Tao Tennis Center are also worth a stop.

How can I get around Clayton and the greater St. Louis area?

Ready to get out and explore the city? Clayton Station is the closest metro station.

Top Clayton Hotels

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Our top choices for Clayton hotels

1. Clayton Plaza Hotel & Extended Stay

Clayton

Sarah

₩170,849 total

includes taxes & fees

Nov 22 - Nov 23

A modern bathroom with a glass-enclosed shower, two sinks with faucets, and a large mirror.

2. Le Méridien St. Louis Clayton

Clayton

Marsha

₩238,967 total

includes taxes & fees

Nov 8 - Nov 9

A rooftop terrace with modern outdoor seating, a fire pit, and a view of the cityscape.

3. AC Hotel St. Louis Clayton

Clayton

anthony

₩199,941 total

includes taxes & fees

Nov 8 - Nov 9

A rooftop terrace with a fire feature, outdoor seating, and a city view.

4. Residence Inn By Marriott St. Louis Clayton

Clayton

Carol

₩264,658 total

includes taxes & fees

Nov 15 - Nov 16

An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.

5. The Ritz-Carlton, St. Louis

Clayton

Kennedy

₩886,097 total

includes taxes & fees

Nov 27 - Nov 28

A modern lounge area with a stone fireplace, comfortable seating, and a bar in the background.

6. Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Clayton

Kevin

₩185,567 total

includes taxes & fees

Nov 8 - Nov 9

A modern lobby with a fireplace, seating area, and a kitchen counter.

7. Homewood Suites by Hilton St Louis - Galleria

Clayton

Denise

₩187,143 total

includes taxes & fees

Nov 29 - Nov 30

A traditional Tudor-style building with a black awning labeled "28 Sally's Inn."

8. Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Clayton

Jennifer

₩244,870 total

includes taxes & fees

Nov 8 - Nov 9

The exterior of the Charles F. Knight Center with a stone facade, large arched entrance, and a sign above the doors.

9. The Knight Center at Washington University

1.3 km from Clayton

jeffrey

₩186,585 total

includes taxes & fees

Nov 28 - Nov 29

An outdoor patio with a fire pit, seating, and a building in the background.

10. Courtyard by Marriott St. Louis Brentwood

1.7 km from Clayton

Anna

₩192,236 total

includes taxes & fees

Nov 8 - Nov 9

A digital display with three screens showing hotel information.

11. SpringHill Suites St. Louis Brentwood

2.4 km from Clayton

Aaron

₩196,900 total

includes taxes & fees

Nov 9 - Nov 10

A grand building with a fountain in front.

12. The Cheshire

1.8 km from Clayton

Matthew

₩235,072 total

includes taxes & fees

Nov 15 - Nov 16

An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.

13. Drury Plaza Hotel St. Louis Brentwood

2.5 km from Clayton

Stacey Rochelle

₩202,781 total

includes taxes & fees

Nov 29 - Nov 30

A modern lobby with a staircase, seating area, and wall-mounted artwork.

14. Moonrise Hotel

2.6 km from Clayton

Jennifer

₩236,079 total

includes taxes & fees

Nov 18 - Nov 19

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

15. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 3.9 km from Clayton

Greg

₩205,108 total

includes taxes & fees

Nov 15 - Nov 16

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

16. Wingate by Wyndham St. Louis Airport

11.5 km from Clayton

Cindy

₩145,403 total

includes taxes & fees

Nov 2 - Nov 3

A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

17. The Royal Sonesta Chase Park Plaza St. Louis

Central West End, 5.1 km from Clayton

Sara

₩251,184 total

includes taxes & fees

Nov 22 - Nov 23

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

18. Hyatt Select St. Louis Airport

10.7 km from Clayton

Thadora

₩212,423 total

includes taxes & fees

Nov 3 - Nov 4

An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

19. Home2 Suites by Hilton St. Louis/Forest Park

The Grove, 5.6 km from Clayton

Molly

₩238,214 total

includes taxes & fees

Dec 1 - Dec 2

A spacious lobby with a high ceiling, a central chandelier, and a patterned floor.

20. River City Casino & Hotel

13.6 km from Clayton

jodi

₩179,835 total

includes taxes & fees

Nov 17 - Nov 18

View all properties

Compare popular hotels in Clayton

Property	Property class	Guest rating
Residence Inn By Marriott St. Louis Clayton	3.0 star property	9.4 Exceptional 250 reviews	View
AC Hotel St. Louis Clayton	2.0 star property	9.2 Wonderful 423 reviews	View
The Ritz-Carlton, St. Louis	5.0 star property	9.2 Wonderful 587 reviews	View
Clayton Plaza Hotel & Extended Stay	3.5 star property	8.8 Excellent 3,506 reviews	View
Le Méridien St. Louis Clayton	4.0 star property	8.8 Excellent 798 reviews	View

Where to stay in Clayton

Find the best Clayton areas and neighborhoods for the activities you enjoy most.

The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Old Courthouse or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

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A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

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A historic building with a green dome and adjacent modern high-rise buildings.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

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A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

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A large airplane suspended in a net structure in an urban setting with modern buildings in the background.

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

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Top Clayton Hotel Reviews

Pear Tree Inn St. Louis Near Union Station

8/10 Good

"During snack time a worker used his dirty hands to pick up tortilla chips off the counter and put them back in the bowl with other chips. I asked him if he could replace the whole bowl of tortilla chips due to contamination. He said “what’s the issue? I’m going to put fresh ones on top!” I asked for a manager and she told him to replace the whole bowl of tortilla chips. I witnessed him use his HAND multiple times to swipe crumps off the counter into his other hand. Totally unacceptable. I did not eat anything that was placed out for 5:30 snack nor breakfast!!"

21C Museum Hotel St Louis

10/10 Excellent

"Location was great, art was fun, loved the little coffee shop (Mike at the coffee shop especially was great so kind!) and the basement sauna. Hot tub was closed while I was there, the chocolates served in the room were old tasting and at check-in I watched the front desk give the couple ahead of me great customer service and then received really mid service in comparison. I would stay here again but those little things were off."

Find hotels in Clayton, St. Louis

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Our top choices for Clayton hotels

1. Clayton Plaza Hotel & Extended Stay

2. Le Méridien St. Louis Clayton

3. AC Hotel St. Louis Clayton

4. Residence Inn By Marriott St. Louis Clayton

5. The Ritz-Carlton, St. Louis

6. Hampton Inn & Suites Clayton/St. Louis-Galleria Area

7. Homewood Suites by Hilton St Louis - Galleria

8. Seven Gables, St. Louis West, a Tribute Portfolio Hotel

9. The Knight Center at Washington University

10. Courtyard by Marriott St. Louis Brentwood

11. SpringHill Suites St. Louis Brentwood

12. The Cheshire

13. Drury Plaza Hotel St. Louis Brentwood

14. Moonrise Hotel

15. Hampton Inn & Suites St. Louis at Forest Park

16. Wingate by Wyndham St. Louis Airport

17. The Royal Sonesta Chase Park Plaza St. Louis

18. Hyatt Select St. Louis Airport

19. Home2 Suites by Hilton St. Louis/Forest Park

20. River City Casino & Hotel

Compare popular hotels in Clayton

Where to stay in Clayton

Downtown St. Louis

St. Charles Historic District

Central West End

Creve Coeur

Downtown West

Top Clayton Hotel Reviews

Pear Tree Inn St. Louis Near Union Station

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