Des Moines Vacation Rentals

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
Feb 20 - Feb 22
In two months
Apr 3 - Apr 5
In three months
May 1 - May 3
In four months
May 29 - May 31
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Des Moines Hotel Reviews

Sonesta Simply Suites Des Moines

Sonesta Simply Suites Des Moines

10/10 Excellent
"A very good hotel for the price. Friendly staff. Clean room, but quite old building and interior. The shower in the room was old and squeaky. "
Bakhtiyor 1-night trip
Posted 2 days ago
Sonesta Simply Suites Des Moines

Find out more about Des Moines

Search for Vacation rentals in Des Moines on Expedia.co.uk! You can easily find your home rentals, villas, Vacation apartments in Des Moines using one of the methods below:

  • View our selection of featured Vacation rentals in Des Moines
  • Use the map to find apartments and other Vacation homes in the Des Moines neighbourhood you prefer
  • Enter your travel dates to view the best deals on Vacation rentals in Des Moines while they last

Look no further and take a look at our great range of rental properties in Des Moines!

Frequently asked questions

Can I find a vacation rental in Des Moines?

Yes, you can find vacation rentals in Des Moines close to Science Center of Iowa, or you can choose a secluded option if you're looking for extra privacy while you relax. Travelers who like culture and the arts give Des Moines high marks for its great live music and lively festivals. Leave some time to check out the acclaimed theater scene and top-notch restaurants during your visit.

How many vacation rentals are there in Des Moines?

With 250 Expedia vacation rentals, you're sure to find just the right place for your Des Moines stay.

What’s there to see and do in Des Moines?

Enjoy the outdoors at Greater Des Moines Botanical Garden and John and Mary Pappajohn Sculpture Park, or simply take in cultural attractions like Simon Estes Riverfront Amphitheater and World Food Prize Hall of Laureates. Walnut Street Bridge and Des Moines Civic Center are other places to visit while you're in town.

What’s a vacation rental in Des Moines like?

A vacation rental is a private property where you can stay for a few weeks or just a few days in Des Moines. Vacation rentals offer extras such as patios, hot tubs, and fire pits so you'll have all the conveniences of home. If you're concerned about cleanliness, vacation rentals can offer a sense of privacy away from shared hotel elevators and busy lobbies while still allowing you the excitement and enjoyment of travel. You'll also get more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive choice for small groups.