The Best Resorts & Hotels with Spas in Florence, SC from ₩218,514 in 2026

A panoramic view of a historic city with a river, prominent domed buildings, and a bridge.

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Our top choices for Florence hotels with a spa

Suite, 2 Bedrooms (Penthouse) | Living area | Flat-screen TV

1. Hotel Florence, Tapestry Collection by Hilton

Florence

Renew your spirit at this historical hotel with an onsite spa offering couples treatments and aromatherapy in the heart of the city.

₩195,101

₩218,514 total

includes taxes & fees

Aug 23 - Aug 24

Quadruple Room, Courtyard View | Outdoor dining

Quadruple Room, Courtyard View | Blackout drapes, iron/ironing board, WiFi (free)

Quadruple Room, Courtyard View | Bathroom | Shower, hair dryer, slippers, towels

2. Horizons Sandhills

Patrick

₩581,131

₩633,433 total

includes taxes & fees

Aug 15 - Aug 16

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Choose what matters most at spa hotels in Florence

Pool

Breakfast included

Hot tub

Gym

4 stars

Top Florence Hotel Reviews

Hampton Inn & Suites Florence Center

10/10 Excellent

"The hotel address on map is not correct, we followed the map on the iPhone, it guided us to the Target."

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

10/10 Excellent

"Excellent property. Breakfast was terrific and space was very comfortable. Room was really good!"

SpringHill Suites by Marriott Florence

8/10 Good

"Property was clean and the staff was very helpful and super nice!"

Frequently asked questions

Looking to vacation at a spa hotel in Florence?

Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers highly recommend the restaurants in Florence. Be sure to pay a visit to the museums during your stay. Spa hotels are a great way to break out of your routine and add a layer of luxury to your holiday.

What is the best spa hotel in Florence?

Hotel Florence, Tapestry Collection by Hilton is a top spa hotel featuring a 24-hour fitness center, a bar, and a restaurant. Enjoy a facial, detox wrap, or Swedish massage at the onsite spa.

How many spa hotels are there in Florence?

Among Expedia's 128 accommodation options in Florence, there is 1 spa hotel.

What's there to see and do in Florence?

Enjoy all that Florence has to offer when you visit Florence County Museum, Florence National Cemetery, and Magnolia Mall. If you have extra time while you're in the area, you might want to see Florence Civic Center and Palmetto Shores Lake.

What is a Florence spa hotel?

Spa hotels in Florence provide lodging and have an on-site spa which offers services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.

Find Resorts & Hotels with Spas in Florence, SC

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