A panoramic view of a historic city with a river, prominent domed buildings, and a bridge.

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Sep 4 - Sep 6
In two weeks
Sep 11 - Sep 13

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Our top choices for Florence, SC (FLO-Florence Regional) hotels

A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.

1. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
3.5 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (1,008 reviews)
"Had a great stay here on a recent road trip. Hotel is clean, updated and staff is friendly."
United States
Brian
The price is ₩156,903
₩175,732 total
includes taxes & fees
Sep 7 - Sep 8
Hyatt Place Florence Downtown
A spacious lobby with a checkered floor, a reception desk, and a chandelier.

2. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
8 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (2,715 reviews)
"Very nice place to stay"
United States
HOMERO
The price is ₩88,912
₩99,581 total
includes taxes & fees
Sep 1 - Sep 2
Howard Johnson by Wyndham Florence
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

3. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
8 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (2,409 reviews)
"Great place to stay and good location."
United States
Hector
The price is ₩109,832
₩123,013 total
includes taxes & fees
Sep 7 - Sep 8
Park Inn by Radisson Florence, SC
A Holiday Inn Express & Suites hotel with a clear entrance, a covered parking area, and a well-maintained exterior.

4. Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 star property
8.3 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (1,002 reviews)
"Good location- very good free breakfast"
United States
Christopher
The price is ₩169,290
₩203,232 total
includes taxes & fees
Sep 27 - Sep 28
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.

5. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
8.2 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (981 reviews)
"Nice stay"
United States
Michelle
The price is ₩162,518
₩182,019 total
includes taxes & fees
Sep 8 - Sep 9
Hampton Inn & Suites Florence-North-I-95
A restaurant with brick walls, framed awards, and a bar area.

6. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
3.0 star property
3.6 km from Florence, SC (FLO-Florence Regional)
8.8 out of 10, Excellent, (652 reviews)
"Beautifully located hotel with plenty of restaurants and bars around. The room was super large and well taken care. Definitely recommended"
United States
Ankh
The price is ₩190,733
₩213,620 total
includes taxes & fees
Sep 11 - Sep 12
Hotel Florence, Tapestry Collection by Hilton
A hotel lobby with a reception desk, seating area, and a television screen.

7. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
9.6 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (1,352 reviews)
"Clean rooms and friendly staff"
United States
Mike
The price is ₩146,126
₩163,662 total
includes taxes & fees
Sep 27 - Sep 28
Comfort Inn & Suites Florence Center Area
An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.

8. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
8.4 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (1,000 reviews)
"Nice clean easy on and off great hotel"
United States
Megan
The price is ₩134,303
₩158,608 total
includes taxes & fees
Sep 8 - Sep 9
Tru by Hilton Florence I-95
A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.

9. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
8 km from Florence, SC (FLO-Florence Regional)
8.2 out of 10, Very Good, (278 reviews)
"property was overall ok what i like the most was that the hotel was steps away from the beach amd an icecream shop right across the street from the hotel"
United States
Francisco
The price is ₩128,660
₩149,538 total
includes taxes & fees
Sep 13 - Sep 14
Spark by Hilton Florence North I-95, SC
A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.

10. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
10.7 km from Florence, SC (FLO-Florence Regional)
9.4 out of 10, Exceptional, (1,003 reviews)
"Out stay was comfortable."
United States
Frederick
The price is ₩185,806
₩208,103 total
includes taxes & fees
Sep 13 - Sep 14
Staybridge Suites Florence - Civic Center by IHG
A modern lobby with seating areas, a reception desk, and a large wall with a decorative panel.

11. Comfort Suites Florence I-95

Comfort Suites Florence I-95
2.5 star property
8.3 km from Florence, SC (FLO-Florence Regional)
8.2 out of 10, Very Good, (1,002 reviews)
"Great area and nice hotel!"
United States
Jennifer
The price is ₩117,390
₩136,983 total
includes taxes & fees
Sep 28 - Sep 29
Comfort Suites Florence I-95
A hotel room with two beds, a wooden headboard, a window with curtains, and a wall-mounted air conditioner.

12. SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence
3.0 star property
9.8 km from Florence, SC (FLO-Florence Regional)
8.4 out of 10, Very Good, (1,001 reviews)
"Clean room- breakfast was great- staff very helpful"
United States
Florence
The price is ₩121,668
₩144,456 total
includes taxes & fees
Sep 20 - Sep 21
SpringHill Suites by Marriott Florence
A hotel entrance with a stone facade, glass doors, and a number '501' above.

13. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
3.0 star property
9.6 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (659 reviews)
"Very nice"
United States
leslie
The price is ₩174,313
₩195,232 total
includes taxes & fees
Sep 7 - Sep 8
Fairfield Inn & Suites by Marriott Florence I-20
A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.

14. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
10.7 km from Florence, SC (FLO-Florence Regional)
9.2 out of 10, Wonderful, (1,007 reviews)
"Wonderful hotel and in a great location!"
United States
Leigh
The price is ₩163,784
₩183,437 total
includes taxes & fees
Sep 27 - Sep 28
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

15. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
2.5 star property
9.9 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (957 reviews)
"Nice staff, clean establishment, and great breakfast!"
United States
Jennifer
The price is ₩151,232
₩169,378 total
includes taxes & fees
Sep 20 - Sep 21
Hampton Inn & Suites Florence Center
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

16. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
3.0 star property
9.7 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (887 reviews)
"Always a good stay"
United Kingdom
William
The price is ₩156,765
₩175,577 total
includes taxes & fees
Sep 10 - Sep 11
TownePlace Suites by Marriott Florence
A hotel room with a desk, a bed, a sofa, a TV, and a mirror.

17. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
10.2 km from Florence, SC (FLO-Florence Regional)
8.4 out of 10, Very Good, (349 reviews)
"-clean rooms, dog friendly and comfy bed."
Canada
Noémie
The price is ₩120,499
₩134,959 total
includes taxes & fees
Sep 28 - Sep 29
Quality Inn & Suites Florence Civic Center
A spacious lobby with a high ceiling, a central seating area with armchairs and a coffee table, a flat-screen TV, and a dining area with tables and chairs.

18. Residence Inn Marriott Florence

Residence Inn Marriott Florence
3.0 star property
9.9 km from Florence, SC (FLO-Florence Regional)
8.8 out of 10, Excellent, (578 reviews)
"Helpful staff and quiet atmosphere, Love it"
United States
TERRENCE
The price is ₩147,544
₩165,249 total
includes taxes & fees
Sep 13 - Sep 14
Residence Inn Marriott Florence
A spacious lobby with a reception desk, seating area, and large windows.

19. Hilton Garden Inn Florence

Hilton Garden Inn Florence
2.5 star property
9.9 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (345 reviews)
"Rooms were clean and staff was friendly."
United States
Derrick
The price is ₩156,875
₩175,701 total
includes taxes & fees
Sep 13 - Sep 14
Hilton Garden Inn Florence
A spacious lobby with a high ceiling, a central seating area, and a staircase leading to an upper level.

20. La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
3.0 star property
8.1 km from Florence, SC (FLO-Florence Regional)
7.8 out of 10, Good, (1,526 reviews)
"Very convenient location Friendly and helpful staff"
United States
Heather
The price is ₩137,496
₩153,996 total
includes taxes & fees
Sep 13 - Sep 14
La Quinta Inn & Suites by Wyndham Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Florence, SC (FLO-Florence Regional)

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.
Hyatt Place Florence Downtown
3.0 star property
9.0
Wonderful
1,008 reviews
View
A spacious lobby with a checkered floor, a reception desk, and a chandelier.
Howard Johnson by Wyndham Florence
2.0 star property
8.6
Excellent
2,715 reviews
View
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
Park Inn by Radisson Florence, SC
2.5 star property
9.0
Wonderful
2,409 reviews
View
A Holiday Inn Express & Suites hotel with a clear entrance, a covered parking area, and a well-maintained exterior.
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 star property
8.6
Excellent
1,002 reviews
View
A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.
Hampton Inn & Suites Florence-North-I-95
2.5 star property
9.0
Wonderful
981 reviews
View

Top Florence Regional Hotel Reviews

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

8/10 Good
"Clean room"
kitty 1-night trip
Posted 8 hours ago
Quality Inn & Suites Florence Civic Center

Guide to exploring around Florence Regional

Florence Regional hotels information

Number of reviews
13,120
Accommodation
137 hotels
Lowest Price
₩99,581
Highest Price
₩213,620

Frequently asked questions

What's the area like near Florence, SC (FLO-Florence Regional)?

Florence, SC (FLO-Florence Regional) is located in a welcoming area of Florence known for its array of dining options. You'll find 71 hotels and other accommodations within a few miles of the airport for a convenient home base.

What's the best place to stay close to Florence, SC (FLO-Florence Regional)?

Hyatt Place Florence Downtown is one of the top choices for your stay and is a popular hotel, featuring free breakfast and free WiFi. It's located 2.2 mi (3.5 km) from Florence, SC (FLO-Florence Regional). Other good choices near the airport include Hotel Florence, Tapestry Collection by Hilton and The Urban Flats.

How many hotels will I find close to Florence, SC (FLO-Florence Regional)?

Expedia has 71 hotels and other accommodations a few miles from the airport.

What can I see and do near the airport in Florence?

Sights like Mcleod Regional Medical Center and Florence Stockade highlight some of the local culture. You can enjoy live performances at Florence Little Theatre and FMU Performing Arts Center. If you've got some time to explore the area around Florence, SC (FLO-Florence Regional), you may want to make a stop by Dr. Eddie Floyd Tennis Center, Southgate Bowling Center, and CarolinaBank Field.