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Find hotels in South Main, Houston from ₩78,857

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Discover 6,370 South Main hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Wyndham Houston near NRG Park/Medical Center
Lobby

Wyndham Houston near NRG Park/Medical Center

3.5 star property
7.2 out of 10, Good, (1121)
"A well kept hotel with great service and atmosphere."
The price is ₩178,497
₩208,841 total
includes taxes & fees
Aug 14 - Aug 15
Wyndham Houston near NRG Park/Medical Center
Candlewood Suites Houston Medical Center by IHG
Exterior

Candlewood Suites Houston Medical Center by IHG

2.5 star property
7.4 out of 10, Good, (789)
"Will definitely be back again!"
The price is ₩107,929
₩126,277 total
includes taxes & fees
Aug 22 - Aug 23
Candlewood Suites Houston Medical Center by IHG
Wingate Houston near NRG Park/Medical Center
Gazebo

Wingate Houston near NRG Park/Medical Center

3.0 star property
6.6 out of 10, (930)
"Great location, rooms were hot/warm. Needs a huge make over."
The price is ₩150,823
₩176,463 total
includes taxes & fees
Aug 14 - Aug 15
Wingate Houston near NRG Park/Medical Center
Quality Inn & Suites NRG Park - Medical Center
1 bedroom, hypo-allergenic bedding, in-room safe, individually decorated

Quality Inn & Suites NRG Park - Medical Center

2.5 star property
6.4 out of 10, (1000)
"Wonderful experience absolutely love my stay"
The price is ₩91,476
₩107,027 total
includes taxes & fees
Aug 26 - Aug 27
Quality Inn & Suites NRG Park - Medical Center
La Quinta Inn & Suites by Wyndham Deer Park
Exterior

La Quinta Inn & Suites by Wyndham Deer Park

3.0 star property
8.4 out of 10, Very Good, (397)
"For the price, best in Deer Park"
The price is ₩120,659
₩141,171 total
includes taxes & fees
Sep 5 - Sep 6
La Quinta Inn & Suites by Wyndham Deer Park
La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd
Pillowtop beds, desk, iron/ironing board, WiFi

La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd

3.5 star property
9.2 out of 10, Wonderful, (1005)
"Good place to stay"
The price is ₩106,268
₩122,208 total
includes taxes & fees
Aug 17 - Aug 18
La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd
Sonesta Simply Suites Houston – NASA Clear Lake
Fridge, microwave, stovetop, dishwasher

Sonesta Simply Suites Houston – NASA Clear Lake

2.5 star property
8.2 out of 10, Very Good, (982)
"Very nice and cost effective place to stay "
The price is ₩95,959
₩112,274 total
includes taxes & fees
Aug 27 - Aug 28
Sonesta Simply Suites Houston – NASA Clear Lake
SureStay Hotel by Best Western Deer Park
1 bedroom, individually furnished, desk, laptop workspace

SureStay Hotel by Best Western Deer Park

2.5 star property
8.4 out of 10, Very Good, (258)
"Very helpful front desk staff - great place to stay for the money."
The price is ₩99,626
₩116,564 total
includes taxes & fees
Aug 14 - Aug 15
SureStay Hotel by Best Western Deer Park
Best Western Webster Hotel, Nasa
Seasonal outdoor pool, pool umbrellas, sun loungers

Best Western Webster Hotel, Nasa

2.5 star property
7.6 out of 10, Good, (1000)
"Great stay"
The price is ₩78,857
₩92,264 total
includes taxes & fees
Sep 1 - Sep 2
Best Western Webster Hotel, Nasa
La Quinta Inn & Suites by Wyndham Houston Channelview
Exterior

La Quinta Inn & Suites by Wyndham Houston Channelview

3.5 star property
8.4 out of 10, Very Good, (788)
"Convenient location "
The price is ₩113,117
₩132,348 total
includes taxes & fees
Sep 12 - Sep 13
La Quinta Inn & Suites by Wyndham Houston Channelview
La Quinta Inn & Suites by Wyndham Pasadena
Room, 2 Queen Beds, Non Smoking | Premium bedding, individually furnished, desk, iron/ironing board

La Quinta Inn & Suites by Wyndham Pasadena

3.0 star property
7.6 out of 10, Good, (696)
"Rooms were very clean"
The price is ₩109,381
₩127,975 total
includes taxes & fees
Sep 7 - Sep 8
La Quinta Inn & Suites by Wyndham Pasadena
Palace Inn Blue Houston East Beltway 8
Cleanliness standards

Palace Inn Blue Houston East Beltway 8

2.5 star property
9.0 out of 10, Wonderful, (301)
"Absolutely love, this place peace and quiet nice rooms, friendly staff"
The price is ₩99,626
₩114,570 total
includes taxes & fees
Sep 8 - Sep 9
Palace Inn Blue Houston East Beltway 8
Bluestar Inn
1 bedroom, individually furnished, desk, iron/ironing board

Bluestar Inn

2.5 star property
9.0 out of 10, Wonderful, (256)
"Nice place at a good rate "
The price is ₩83,022
₩97,136 total
includes taxes & fees
Aug 14 - Aug 15
Bluestar Inn
Best Western Plus Pasadena Inn and Suites
Lobby

Best Western Plus Pasadena Inn and Suites

2.5 star property
8.6 out of 10, Excellent, (426)
"Excellent place to stay"
The price is ₩128,200
₩149,994 total
includes taxes & fees
Aug 19 - Aug 20
Best Western Plus Pasadena Inn and Suites
Best Western Plus Heritage Inn
Lobby

Best Western Plus Heritage Inn

3.0 star property
8.0 out of 10, Very Good, (713)
"Great location for our event."
The price is ₩108,344
₩126,775 total
includes taxes & fees
Aug 14 - Aug 15
Best Western Plus Heritage Inn
Palace Inn Blue Edgebrook
Free daily on-the-go breakfast

Palace Inn Blue Edgebrook

3.0 star property
9.4 out of 10, Exceptional, (129)
"Really great hospitality"
The price is ₩113,180
₩136,392 total
includes taxes & fees
Aug 14 - Aug 15
Palace Inn Blue Edgebrook
Sonesta Essential Houston Hobby Airport
Lobby

Sonesta Essential Houston Hobby Airport

2.5 star property
6.4 out of 10, (1005)
"I love the breakfast."
The price is ₩87,173
₩110,087 total
includes taxes & fees
Aug 14 - Aug 15
Sonesta Essential Houston Hobby Airport
Days Inn & Suites by Wyndham Houston Hobby Airport
Exterior

Days Inn & Suites by Wyndham Houston Hobby Airport

2.5 star property
8.6 out of 10, Excellent, (1002)
"It was good stay"
The price is ₩109,312
₩127,895 total
includes taxes & fees
Aug 14 - Aug 15
Days Inn & Suites by Wyndham Houston Hobby Airport
Houston Marriott South at Hobby Airport
Lobby

Houston Marriott South at Hobby Airport

3.5 star property
8.8 out of 10, Excellent, (1171)
"Great stay!"
The price is ₩115,124
₩138,494 total
includes taxes & fees
Aug 15 - Aug 16
Houston Marriott South at Hobby Airport
Four Points by Sheraton Houston Hobby Airport
Lobby

Four Points by Sheraton Houston Hobby Airport

3.0 star property
7.8 out of 10, Good, (1001)
"This property is one of the worst ones I’ve stayed, TV not working, air-conditioning in the room not working, very noisy portable unit in the room,( can’t sleep with that noise so room was 78degrees.) Breakfast buffet is an absolute joke, don’t offer a breakfast buffet if you just wanna offer cereal hard biped eggs and juice. I have traveled all over the world and this is the worst hotel I have stayed at. "
The price is ₩81,915
₩95,842 total
includes taxes & fees
Aug 14 - Aug 15
Four Points by Sheraton Houston Hobby Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in South Main

Find the best South Main areas and neighborhoods for the activities you enjoy most.
Discovery Green which includes a city, central business district and a high rise building
Downtown Houston map

Downtown Houston

3 out of top 10 points of interest in this area

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

The Galleria map

The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Gerald D. Hines Waterwall Park.

Texas Medical Center map

Texas Medical Center

1 out of top 10 points of interest in this area

Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

Houston Heights map

Houston Heights

You'll enjoy the coffeehouses and live music in Houston Heights. You might want to make time for a stop at The Heights Theater or Artcar Museum.

Menil Collection which includes art and interior views
Montrose map

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Westheimer Rd while you're exploring the area.

Top South Main Hotel Reviews

Blossom Hotel Houston

Blossom Hotel Houston

10/10 Excellent
"It was one person went out thay way for us. That was very appreciated. Pablo made our stay wonderful."
Shayla 4-night trip
Posted 17 hours ago
Blossom Hotel Houston

Frequently asked questions

What is South Main like?

You'll be sure to have fun visiting Houston's South Main neighborhood. Consider a visit to NRG Park as part of your South Main travel plans.

Where is the best hotel for a stay in South Main?

Based on Expedia customer reviews, Comfort Suites near Texas Medical Center - NRG Stadium is the highest ranked property in South Main. This hotel is a short 9-minute walk from NRG Stadium, and it offers free breakfast and free parking. Other top choices in the neighborhood include Candlewood Suites Houston Medical Center by IHG and Quality Inn & Suites NRG Park - Medical Center.

How many hotels will I be able to find in South Main?

If you're searching for places to stay in Houston, Expedia has something to meet your needs with 55 South Main hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in South Main, will I receive a refund?

Yes, the majority of hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best options available in South Main.

Where can I learn more about changing or cancelling my trip to South Main?

For more details about changing or cancelling your trip to South Main, head over to our customer service page.

What can I see and do in this Houston neighborhood?

NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, be sure to visit other sights like NRG Stadium or NRG Arena.

How can I get around South Main and the greater Houston area?

Ready to get out and explore the city? Fannin South Station is the closest metro station.