The Best Hotels Closest to Mark Twain Boyhood Home and Museum in Hannibal for 2026

Our top choices for Mark Twain Boyhood Home and Museum hotels

55-inch TV with cable channels, Netflix, Hulu

1. Riverside Inn Hannibal

0.2 km from Mark Twain Boyhood Home and Museum

Michael

₩325,729 total

includes taxes & fees

Aug 3 - Aug 4

Down comforters, blackout drapes, iron/ironing board, WiFi (free)

2. Lighthouse Inn & Suites

0.6 km from Mark Twain Boyhood Home and Museum

Kari

₩306,051 total

includes taxes & fees

Jul 30 - Jul 31

3. Garden House Bed and Breakfast

0.3 km from Mark Twain Boyhood Home and Museum

Andy Nicole

₩181,870 total

includes taxes & fees

Jul 25 - Jul 26

4. Motel 6 Hannibal, MO

2.9 km from Mark Twain Boyhood Home and Museum

Darion

₩97,093 total

includes taxes & fees

Aug 21 - Aug 22

5. Super 8 by Wyndham Hannibal

3 km from Mark Twain Boyhood Home and Museum

Ariel

₩107,443 total

includes taxes & fees

Aug 8 - Aug 9

6. Sleep Inn & Suites Hannibal West

6.6 km from Mark Twain Boyhood Home and Museum

Catherine

₩210,819 total

includes taxes & fees

Jul 26 - Jul 27

7. Quality Inn & Suites Hannibal West

6.4 km from Mark Twain Boyhood Home and Museum

Karen

₩137,946 total

includes taxes & fees

Aug 9 - Aug 10

In-room safe, desk, blackout drapes, iron/ironing board

8. Comfort Inn & Suites - Hannibal

4.7 km from Mark Twain Boyhood Home and Museum

Tracey

₩152,416 total

includes taxes & fees

Aug 2 - Aug 3

Desk, laptop workspace, WiFi (free), alarm clocks

9. Days Inn by Wyndham Hannibal

4.9 km from Mark Twain Boyhood Home and Museum

Marcia

₩95,505 total

includes taxes & fees

Aug 19 - Aug 20

10. Howard Johnson BY Wyndham Hannibal

5 km from Mark Twain Boyhood Home and Museum

Melissa

₩114,191 total

includes taxes & fees

Jul 25 - Jul 26

11. Baymont by Wyndham Hannibal

5 km from Mark Twain Boyhood Home and Museum

Jason

₩102,174 total

includes taxes & fees

Aug 3 - Aug 4

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Compare popular hotels close to Mark Twain Boyhood Home and Museum

Property	Property class	Guest rating
Riverside Inn Hannibal	2.5 star property	9.6 Exceptional 184 reviews	View
Lighthouse Inn & Suites	4.0 star property	9.0 Wonderful 35 reviews	View
Garden House Bed and Breakfast	2.0 star property	8.4 Very Good 45 reviews	View
Motel 6 Hannibal, MO	2.0 star property	7.4 Good 1,000 reviews	View
Super 8 by Wyndham Hannibal	2.0 star property	7.2 Good 1,004 reviews	View

Top Mark Twain Boyhood Home and Museum Hotel Reviews

Microtel Inn & Suites by Wyndham Quincy Downtown/River Area

8/10 Good

"Good"

Quality Inn & Suites Hannibal West

10/10 Excellent

"The breakfast foods were tasty and hot every day. The hot buffet included home made biscuits and gravy, sausage patties, hash brown potatoes and scrambled eggs. There was also yogurt, 3 choices of dry cereal and you could make waffles. The swimming pool, spa, and exercise room looked nice. The room was comfortable."

Econo Lodge Quincy

8/10 Good

"There was no shampoo or bath gel in the bathroom. The toilet tissue was less than a quarter of a roll, and there was no spare. No facial tissues. I have stayed here in the past and these items were always there. I have stayed at this hotel on several other occassions and I have always found it to be very clean and the staff to be very amendable. I do recommend this hotel for its convenience to activities in the area, reasonable pricing, parking and service. There is a nice restaurant right behind this facility and other eating establishments close by. It is currently being updated, so the free breakfast is currently not available. I will be back in this area again in November and this is where I plan to stay."

Super 8 by Wyndham Hannibal

8/10 Good

"The rooms were clean and beds were comfortable. The only issue was the smoke detector in room 215 was missing from the ceiling. It was nice to have an outdoor pool on the property. Normal hours are until 9:00pm. I would think with summer and vacation travelers the pool could at least be open until 10:00 pm."

Lighthouse Inn & Suites

8/10 Good

"Hotels.com [and other third party sites] are not booking correctly with this hotel. I don't believe that the room I rented was worth what I paid. When we got there it was 8pm and we had read that check in is until 9pm. The office was closed with a sign on the door: "text/call us for emergencies. And third party sites are not being communicated with them well." I had to call to be texted a code and room to enter on the spot, thankfully. The room was small for 2 queen beds. Nice, new fridge. Maybe 10 parking spots in the lot. It was clear the rooms had been recently renovated because their were codes still visible on the sheets and bathroon door and the freezer still had the instruction manual inside. The TV kept being changed by [assuming] another room because it kept going back to the same channel/show, We watched cautiously with the idea that our remote might change another TV, too. Also, there was not a light switch for lights in the bed area, and they had to be turned on manually. The pool was great but we only used it once for a short time. There was consctruction on the street in front which made the walk into town a little wonky, but fine. We did experience a fire alarm around midnight on the first night and stayed in car until given "clear"- The staff never followed up about it. So most likely will not stay there again with those prices. [We were also under the assumption that there was a hot tub in the room - not true]"

Hotels near other Mark Twain Boyhood Home and Museum attractions

Mark Twain Memorial Lighthouse

8.8/10 (143 reviews)

You can find out about the history of Hannibal with a stop at Mark Twain Memorial Lighthouse. While in this family-friendly area, you can savor the top-notch restaurants.

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Frequently asked questions

What's the area like around Mark Twain Boyhood Home and Museum?

Mark Twain Boyhood Home and Museum is located in a welcoming area of Hannibal known for its array of dining options. If you're looking for a convenient place to stay, check out the 41 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay close to Mark Twain Boyhood Home and Museum?

Adjacent to Mark Twain Boyhood Home and Museum, Best Western On The River is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. Other good choices close by include Lighthouse Inn & Suites and Riverside Inn Hannibal.

How many hotels are there near Mark Twain Boyhood Home and Museum?

Expedia has 41 hotels and other accommodations within a mile from Mark Twain Boyhood Home and Museum.

If I need to cancel the hotel reservation for my stay near Mark Twain Boyhood Home and Museum, will I receive a refund?

Yes! You'll find that most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to get top deals close to Mark Twain Boyhood Home and Museum.

Where can I learn more about changing or cancelling my trip in the area near Mark Twain Boyhood Home and Museum?

To access more information about changing or cancelling your stay near Mark Twain Boyhood Home and Museum, go to https://www.expedia.com/service/.

What can I see and do near Mark Twain Boyhood Home and Museum?

You'll want to browse the exhibits at Jim's Journey: The Huck Finn Freedom Center and Molly Brown Museum and Home. Mark Twain Memorial Lighthouse, Rockcliffe Mansion, and Mark Twain Cave are notable landmarks to explore if you're in the area. You can enjoy live performances at Planters Barn Theater and Bluff City Theater.

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Our top choices for Mark Twain Boyhood Home and Museum hotels

1. Riverside Inn Hannibal

2. Lighthouse Inn & Suites

3. Garden House Bed and Breakfast

4. Motel 6 Hannibal, MO

5. Super 8 by Wyndham Hannibal

6. Sleep Inn & Suites Hannibal West

7. Quality Inn & Suites Hannibal West

8. Comfort Inn & Suites - Hannibal

9. Days Inn by Wyndham Hannibal

10. Howard Johnson BY Wyndham Hannibal

11. Baymont by Wyndham Hannibal

Compare popular hotels close to Mark Twain Boyhood Home and Museum

Top Mark Twain Boyhood Home and Museum Hotel Reviews

Microtel Inn & Suites by Wyndham Quincy Downtown/River Area

Quality Inn & Suites Hannibal West

Baymont by Wyndham Hannibal

Comfort Inn & Suites - Hannibal

Stoney Creek Inn Quincy

Econo Lodge Quincy

Sleep Inn & Suites Hannibal West

Super 8 by Wyndham Hannibal

Lighthouse Inn & Suites

Hotels near other Mark Twain Boyhood Home and Museum attractions

Mark Twain Memorial Lighthouse

Planters Barn Theater

Big River Train Town

Jim's Journey: The Huck Finn Freedom Center

Bluff City Theater

Molly Brown Museum and Home

Lovers Leap

Riverview Park

Frequently asked questions

Find hotels near Mark Twain Boyhood Home and Museum, Hannibal from ₩95,505

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Our top choices for Mark Twain Boyhood Home and Museum hotels

1. Riverside Inn Hannibal

2. Lighthouse Inn & Suites

3. Garden House Bed and Breakfast

4. Motel 6 Hannibal, MO

5. Super 8 by Wyndham Hannibal

6. Sleep Inn & Suites Hannibal West

7. Quality Inn & Suites Hannibal West

8. Comfort Inn & Suites - Hannibal

9. Days Inn by Wyndham Hannibal

10. Howard Johnson BY Wyndham Hannibal

11. Baymont by Wyndham Hannibal

Compare popular hotels close to Mark Twain Boyhood Home and Museum

Top Mark Twain Boyhood Home and Museum Hotel Reviews

Microtel Inn & Suites by Wyndham Quincy Downtown/River Area

Hotels near other Mark Twain Boyhood Home and Museum attractions

Mark Twain Memorial Lighthouse

Frequently asked questions