The Best Hotels Closest to Mark Twain Boyhood Home and Museum in Hannibal for 2026

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Our top choices for Mark Twain Boyhood Home and Museum hotels

55-inch TV with cable channels, Netflix, Hulu

1. Riverside Inn Hannibal

0.2 km from Mark Twain Boyhood Home and Museum

₩325,640 total

includes taxes & fees

Jul 26 - Jul 27

Down comforters, blackout drapes, iron/ironing board, WiFi (free)

2. Lighthouse Inn & Suites

0.6 km from Mark Twain Boyhood Home and Museum

Kari

₩305,968 total

includes taxes & fees

Jul 26 - Jul 27

3. Garden House Bed and Breakfast

0.3 km from Mark Twain Boyhood Home and Museum

Christopher

₩181,796 total

includes taxes & fees

Jul 25 - Jul 26

4. Motel 6 Hannibal, MO

2.9 km from Mark Twain Boyhood Home and Museum

Darion

₩97,054 total

includes taxes & fees

Aug 21 - Aug 22

5. Super 8 by Wyndham Hannibal

3 km from Mark Twain Boyhood Home and Museum

Ariel

₩107,414 total

includes taxes & fees

Aug 8 - Aug 9

6. Sleep Inn & Suites Hannibal West

6.6 km from Mark Twain Boyhood Home and Museum

Catherine

₩194,394 total

includes taxes & fees

Aug 23 - Aug 24

7. Quality Inn & Suites Hannibal West

6.4 km from Mark Twain Boyhood Home and Museum

Karen

₩139,603 total

includes taxes & fees

Aug 2 - Aug 3

In-room safe, desk, blackout drapes, iron/ironing board

8. Comfort Inn & Suites - Hannibal

4.7 km from Mark Twain Boyhood Home and Museum

Tracey

₩156,294 total

includes taxes & fees

Aug 16 - Aug 17

Desk, laptop workspace, WiFi (free), alarm clocks

9. Days Inn by Wyndham Hannibal

4.9 km from Mark Twain Boyhood Home and Museum

Marcia

₩101,450 total

includes taxes & fees

Jul 26 - Jul 27

10. Howard Johnson BY Wyndham Hannibal

5 km from Mark Twain Boyhood Home and Museum

Melissa

₩114,145 total

includes taxes & fees

Jul 29 - Jul 30

11. Baymont by Wyndham Hannibal

5 km from Mark Twain Boyhood Home and Museum

Jason

₩102,131 total

includes taxes & fees

Jul 30 - Jul 31

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Compare popular hotels close to Mark Twain Boyhood Home and Museum

Property	Property class	Guest rating
Riverside Inn Hannibal	2.5 star property	9.6 Exceptional 184 reviews	View
Lighthouse Inn & Suites	4.0 star property	9.0 Wonderful 35 reviews	View
Garden House Bed and Breakfast	2.0 star property	8.4 Very Good 46 reviews	View
Motel 6 Hannibal, MO	2.0 star property	7.4 Good 1,001 reviews	View
Super 8 by Wyndham Hannibal	2.0 star property	7.2 Good 1,006 reviews	View

Top Mark Twain Boyhood Home and Museum Hotel Reviews

Garden House Bed and Breakfast

10/10 Excellent

"This was a charming and delightful stay. We enjoyed meeting Chris and hearing about the history of the house, the area around it, and Hannibal in general. The home has been beautifully maintained. Our room was cozy and each time we returned, it felt like coming home. We also enjoyed meeting CeeCee the beautiful gray house kitty."

Econo Lodge Quincy

8/10 Good

"There was no shampoo or bath gel in the bathroom. The toilet tissue was less than a quarter of a roll, and there was no spare. No facial tissues. I have stayed here in the past and these items were always there. I have stayed at this hotel on several other occassions and I have always found it to be very clean and the staff to be very amendable. I do recommend this hotel for its convenience to activities in the area, reasonable pricing, parking and service. There is a nice restaurant right behind this facility and other eating establishments close by. It is currently being updated, so the free breakfast is currently not available. I will be back in this area again in November and this is where I plan to stay."

Lighthouse Inn & Suites

8/10 Good

"Hotels.com [and other third party sites] are not booking correctly with this hotel. I don't believe that the room I rented was worth what I paid. When we got there it was 8pm and we had read that check in is until 9pm. The office was closed with a sign on the door: "text/call us for emergencies. And third party sites are not being communicated with them well." I had to call to be texted a code and room to enter on the spot, thankfully. The room was small for 2 queen beds. Nice, new fridge. Maybe 10 parking spots in the lot. It was clear the rooms had been recently renovated because their were codes still visible on the sheets and bathroon door and the freezer still had the instruction manual inside. The TV kept being changed by [assuming] another room because it kept going back to the same channel/show, We watched cautiously with the idea that our remote might change another TV, too. Also, there was not a light switch for lights in the bed area, and they had to be turned on manually. The pool was great but we only used it once for a short time. There was consctruction on the street in front which made the walk into town a little wonky, but fine. We did experience a fire alarm around midnight on the first night and stayed in car until given "clear"- The staff never followed up about it. So most likely will not stay there again with those prices. [We were also under the assumption that there was a hot tub in the room - not true]"

Hotels near other Mark Twain Boyhood Home and Museum attractions

Mark Twain Memorial Lighthouse

8.8/10 (143 reviews)

You can find out about the history of Hannibal with a stop at Mark Twain Memorial Lighthouse. While in this family-friendly area, you can savor the top-notch restaurants.

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Frequently asked questions

What's the area like around Mark Twain Boyhood Home and Museum?

Mark Twain Boyhood Home and Museum is located in a welcoming area of Hannibal known for its array of dining options. If you're looking for a convenient place to stay, check out the 41 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay close to Mark Twain Boyhood Home and Museum?

Adjacent to Mark Twain Boyhood Home and Museum, Best Western On The River is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. Other good choices close by include Lighthouse Inn & Suites and Riverside Inn Hannibal.

How many hotels are there near Mark Twain Boyhood Home and Museum?

Expedia has 41 hotels and other accommodations within a mile from Mark Twain Boyhood Home and Museum.

If I need to cancel the hotel reservation for my stay near Mark Twain Boyhood Home and Museum, will I receive a refund?

Yes! You'll find that most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to get top deals close to Mark Twain Boyhood Home and Museum.

Where can I learn more about changing or cancelling my trip in the area near Mark Twain Boyhood Home and Museum?

To access more information about changing or cancelling your stay near Mark Twain Boyhood Home and Museum, go to https://www.expedia.com/service/.

What can I see and do near Mark Twain Boyhood Home and Museum?

You'll want to browse the exhibits at Jim's Journey: The Huck Finn Freedom Center and Molly Brown Museum and Home. Mark Twain Memorial Lighthouse, Rockcliffe Mansion, and Mark Twain Cave are notable landmarks to explore if you're in the area. You can enjoy live performances at Planters Barn Theater and Bluff City Theater.

Find hotels near Mark Twain Boyhood Home and Museum, Hannibal from ₩97,054

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Our top choices for Mark Twain Boyhood Home and Museum hotels

1. Riverside Inn Hannibal

2. Lighthouse Inn & Suites

3. Garden House Bed and Breakfast

4. Motel 6 Hannibal, MO

5. Super 8 by Wyndham Hannibal

6. Sleep Inn & Suites Hannibal West

7. Quality Inn & Suites Hannibal West

8. Comfort Inn & Suites - Hannibal

9. Days Inn by Wyndham Hannibal

10. Howard Johnson BY Wyndham Hannibal

11. Baymont by Wyndham Hannibal

Compare popular hotels close to Mark Twain Boyhood Home and Museum

Top Mark Twain Boyhood Home and Museum Hotel Reviews

Garden House Bed and Breakfast

Hotels near other Mark Twain Boyhood Home and Museum attractions

Mark Twain Memorial Lighthouse

Frequently asked questions