A modern building with a curved glass facade, surrounded by a well-maintained lawn and several trees.

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Our top choices for Mcleod Regional Medical Center hotels

A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.
A multi-story hotel with a modern facade, featuring a prominent 'Hyatt Place' sign on the right.
A modern lounge area with brick walls, large windows, and contemporary furniture.
A modern bar area with a long counter, bar stools, and a variety of bottles and glasses.

1. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
0.7 km from Mcleod Regional Medical Center
United States
Ivette
₩134,100
₩150,192 total
includes taxes & fees
Nov 3 - Nov 4
Hyatt Place Florence Downtown
A restaurant with brick walls, framed awards, and a bar area.
A bar area with a curved counter, multiple stools, and a brick wall backdrop.
A spacious living room with a wooden floor, a ceiling fan, and a dining area with a wooden table and chairs.
An outdoor patio area with a brick wall, a covered seating area with string lights, and potted plants.

2. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
0.8 km from Mcleod Regional Medical Center
United States
Ankh
₩185,836
₩208,137 total
includes taxes & fees
Oct 25 - Oct 26
Hotel Florence, Tapestry Collection by Hilton
A sign for the Rodeway Inn.

3. Rodeway Inn Florence Downtown

Rodeway Inn Florence Downtown
1.2 km from Mcleod Regional Medical Center
United States
F
₩56,993
₩65,750 total
includes taxes & fees
Nov 15 - Nov 16
Rodeway Inn Florence Downtown
A modern kitchen with stainless steel appliances, a gray sofa, and a ceiling fan.
A modern kitchen with a built-in dishwasher, a large island with a sink, pendant lights, and a ceiling fan.
A modern living room with a grey sofa, a round coffee table, a grey armchair with patterned cushions, a floor lamp, and a large TV mounted on the wall.
A modern living room with a brick wall, a grey sofa, a wooden coffee table, and a view through large windows.

4. The Urban Flats

The Urban Flats
0.8 km from Mcleod Regional Medical Center
₩383,526
₩630,701 total
includes taxes & fees
Oct 19 - Oct 20
The Urban Flats
A hotel lobby with a reception desk, seating area, and a television screen.
A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.
A spacious dining area with multiple tables and chairs, large windows, and a flat-screen TV mounted on the wall.
A Comfort Inn & Suites hotel with a covered entrance, brick facade, and multiple windows.

5. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
7 km from Mcleod Regional Medical Center
United States
Mila
₩135,642
₩151,917 total
includes taxes & fees
Nov 8 - Nov 9
Comfort Inn & Suites Florence Center Area
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.
A Hampton Inn & Suites with a large sign, brick facade, and a parking lot.
A hotel lobby with a reception desk, seating area, and a welcome mat.
A lobby with a fireplace, seating area, and a television.

6. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
7.2 km from Mcleod Regional Medical Center
United States
Ryan
₩152,740
₩171,070 total
includes taxes & fees
Oct 25 - Oct 26
Hampton Inn & Suites Florence Center
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.
A modern living room with a grey sofa, a flat-screen TV, geometric wall art, and a bookshelf with decorative items.
A modern hotel with a 'Park Inn by Radisson' sign, featuring a covered entrance, multiple windows, and a parking lot.

7. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
5.5 km from Mcleod Regional Medical Center
United States
Juan
₩119,751
₩134,121 total
includes taxes & fees
Oct 25 - Oct 26
Park Inn by Radisson Florence, SC
A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.
A hotel lobby with a reception desk, seating area, and artwork on the walls.
A large, two-story building with a central entrance flanked by columns, labeled "DIR FRANK B. LEE NURSING BUILDING."
An outdoor patio area with brick walls, a fire pit, and outdoor seating.

8. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
9.1 km from Mcleod Regional Medical Center
United States
Christopher
₩170,307
₩204,022 total
includes taxes & fees
Nov 1 - Nov 2
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
A spacious lobby with a checkered floor, a reception desk, and a chandelier.
A spacious dining area with multiple tables and chairs, large windows offering a view of the parking lot, and a television mounted on the wall.
A two-story building with a brick facade, a flat roof, and a covered entrance area.
A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.

9. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
5.5 km from Mcleod Regional Medical Center
United States
Alanda
₩86,629
₩97,026 total
includes taxes & fees
Oct 21 - Oct 22
Howard Johnson by Wyndham Florence
A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.
An outdoor kitchen area with a grill, a pool, and a covered seating area.
A hotel room with a bed, a desk, a TV, a refrigerator, and a painting on the wall.
A conference room with round tables, chairs, and a carpeted floor.

10. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
8.1 km from Mcleod Regional Medical Center
United States
Tishia
₩181,035
₩202,760 total
includes taxes & fees
Nov 1 - Nov 2
Staybridge Suites Florence - Civic Center by IHG
A hotel entrance with a stone facade, glass doors, and a number '501' above.
An indoor swimming pool with a tiled floor, a pool ladder, and lounge chairs.
A hotel reception area with a wooden floor, a reception desk, a seating area with chairs, and a decorative wall with a tree pattern.
A modern living room with a stone fireplace, a blue sofa, a brown leather chair, and a round coffee table.

11. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
6.9 km from Mcleod Regional Medical Center
United States
Alma
₩158,439
₩177,452 total
includes taxes & fees
Oct 25 - Oct 26
Fairfield Inn & Suites by Marriott Florence I-20
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.
A modern hotel room with a kitchenette, a grey sofa, a dining area, and a sign that reads "A Great Day Starts With Breakfast."
A reception area with a wooden desk, a map on the wall, and a sign welcoming visitors to Florence, SC.
A modern lounge area with a sofa, armchairs, and small tables.

12. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
7 km from Mcleod Regional Medical Center
United States
Crystal
₩147,041
₩164,686 total
includes taxes & fees
Nov 1 - Nov 2
TownePlace Suites by Marriott Florence
An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.
A modern hotel with a prominent 'TRU by Hilton' sign, a well-lit entrance, and a landscaped front yard.
A snack kiosk with a variety of snacks and beverages, a sign for a 24/7 market, and a sign for local items.
A modern hotel restaurant with a breakfast bar, seating area, and a view of the city.

13. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
5.9 km from Mcleod Regional Medical Center
United States
Tiffany
₩147,041
₩172,665 total
includes taxes & fees
Oct 22 - Oct 23
Tru by Hilton Florence I-95
A spacious lobby with a high ceiling, a central seating area with armchairs and a coffee table, a flat-screen TV, and a dining area with tables and chairs.
A modern hotel lobby with a fireplace, seating area, and a reception desk.
A hotel with a modern design, featuring multiple floors and a parking lot.
A modern hotel lobby with a central seating area, a large abstract painting, and a patterned carpet.

14. Residence Inn Marriott Florence

Residence Inn Marriott Florence
7.2 km from Mcleod Regional Medical Center
United States
Teri
₩143,755
₩161,004 total
includes taxes & fees
Nov 8 - Nov 9
Residence Inn Marriott Florence
A spacious lobby with a reception desk, seating area, and large windows.
A Hilton Garden Inn with a large, multi-story building, a covered entrance, and a parking lot.
An indoor swimming pool with clear poolside areas, a lifeguard station, and a view of the outside.
A reception area with a counter, a sign for 'The Pavilion Pantry', and a green wall.

15. Hilton Garden Inn Florence

Hilton Garden Inn Florence
7.2 km from Mcleod Regional Medical Center
United States
Derrick
₩158,439
₩177,452 total
includes taxes & fees
Oct 25 - Oct 26
Hilton Garden Inn Florence
A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.
A Hampton Inn & Suites hotel with a well-lit entrance, multiple floors, and a parking area.
An indoor swimming pool with clear water, surrounded by a checkered wall pattern, and equipped with multiple seating areas and a lifeguard station.
A lobby with leather sofas, a coffee table, potted plants, and a reception desk.

16. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
5.7 km from Mcleod Regional Medical Center
United States
Ashokraju
₩164,138
₩183,835 total
includes taxes & fees
Oct 22 - Oct 23
Hampton Inn & Suites Florence-North-I-95
A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.
A hotel room with two beds, a desk with a chair, a television, and a window with curtains.
A modern cafeteria with long wooden tables, green chairs, and yellow accents.
A hotel with a modern design, featuring a prominent sign for the 'Country Inn & Suites by Radisson.'

17. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
5.5 km from Mcleod Regional Medical Center
United States
Tienia
₩112,845
₩131,685 total
includes taxes & fees
Nov 8 - Nov 9
Spark by Hilton Florence North I-95, SC
A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.
A snack and beverage display area with shelves stocked with various brands and a refrigerator with beverages.
A coffee station with two coffee machines and a display of coffee pods and cups.
A reception area with a modern design, featuring a reception desk, a digital display, and a sign for Holiday Inn Express & Suites.

18. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
8 km from Mcleod Regional Medical Center
United States
Leigh
₩152,874
₩171,220 total
includes taxes & fees
Nov 1 - Nov 2
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
A hotel room with a desk, chair, bed, and a yellow sofa.
A swimming pool with lounge chairs and a building with balconies.
A hotel with a green roof, a sign reading 'Quality Inn & Suites by Choice Hotels,' and a landscaped front yard with small trees and shrubs.
A hotel dining area with wooden tables and chairs, a fireplace, and a television.

19. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
7.5 km from Mcleod Regional Medical Center
United States
Sharhonda
₩119,483
₩133,820 total
includes taxes & fees
Oct 25 - Oct 26
Quality Inn & Suites Florence Civic Center
Terrace/patio
A spacious lobby with a reception desk, seating area with patterned chairs, and a coffee station.
A hotel room with a bed, a desk, a green sofa, and a painting on the wall.
An indoor swimming pool with lounge chairs and exercise equipment.

20. Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC
7.7 km from Mcleod Regional Medical Center
United States
saleh
₩150,782
₩176,855 total
includes taxes & fees
Nov 10 - Nov 11
Home2 Suites by Hilton Florence, SC
View all properties

Top Mcleod Regional Medical Center Hotel Reviews

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

10/10 Excellent
"Everything was very nice. Good breakfast. Comfortable bed"
Noreen 1-night trip
Posted 3 hours ago
Park Inn by Radisson Florence, SC
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

8/10 Good
"We like that it was right near I 95 and they have parking. I did pick the hotel because of the pool and after a long drive I really wanted to go in the pool, but the pool was closed for the season. The room was nice, but the floors were sticky."
Deborah 1-night trip
Posted 4 hours ago
Spark by Hilton Florence North I-95, SC
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

10/10 Excellent
"Accessible right off 95! Super clean and quiet. Excellent place to sleep and rest! Breakfast was basic, but had boiled eggs, bagels, bread, muffins, coffee, juice, oatmeal,... everything you need to have a good breakfast and continue. Breakfast from 6:30am to 9am."
Gabriela 1-night trip
Posted 5 hours ago
Howard Johnson by Wyndham Florence
Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

8/10 Good
"The staff were great!! Parking was close by and easy. The restaurant bar was a great stop. If you want a refrigerator in your room you need to ask prior to arrival."
Wendy 1-night trip
Posted 6 days ago
Hotel Florence, Tapestry Collection by Hilton
Comfort Suites Florence I-95

Comfort Suites Florence I-95

10/10 Excellent
"Everything was excellent- the staff, the rooms, the parking, you name it. Very satisfied"
Mary 1-night trip
Posted 8 days ago
Comfort Suites Florence I-95

Frequently asked questions

What's the area like around Mcleod Regional Medical Center?
Mcleod Regional Medical Center is located in a welcoming area of Florence known for its array of dining options. If you're looking for a convenient place to stay, check out the 18 hotels and other accommodations you'll find within a mile.
What's the best hotel to stay near Mcleod Regional Medical Center?
Hyatt Place Florence Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a restaurant. It's located just a short 0.4 mi (0.7 km) from Mcleod Regional Medical Center. Other good options within a short distance include Hotel Florence, Tapestry Collection by Hilton and The Urban Flats.
How many hotels will I find near Mcleod Regional Medical Center?
Expedia has 18 hotels and other accommodations within a mile from Mcleod Regional Medical Center.
If I need to cancel the hotel reservation for my stay near Mcleod Regional Medical Center, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to view the best deals near Mcleod Regional Medical Center.
Where can I learn more about changing or cancelling my trip in the area near Mcleod Regional Medical Center?
For more information about updating your stay near Mcleod Regional Medical Center or cancelling it, click here.
What can I see and do near Mcleod Regional Medical Center?
You can enjoy live performances at FMU Performing Arts Center and Florence Little Theatre. You might spend a leisurely day outdoors at Florence Veterans Park and Greenwood Baseball Park and Playground. Create some family memories at Sky Zone Trampoline Park and Tilt Studio.