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Find Resorts & Hotels with Spas in Mount Pleasant, SC

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Check availability on Mount Pleasant Resorts & Hotels with Spas

Our top choices for Mount Pleasant hotels with a spa

Couples treatment rooms, hot stone massages, deep-tissue massages
Harborside at Charleston Harbor Resort and Marina

Harborside at Charleston Harbor Resort and Marina

Harborside at Charleston Harbor Resort and Marina
4.0 star property
Mount Pleasant
8.6 out of 10, Excellent, (2022)
"We had a lovely room and enjoyed all the amenities at this resort on Charleston Marina. Highly recommend!"
United States
Elizabeth
Harborside at Charleston Harbor Resort and Marina
Exterior
The Beach Club at Charleston Harbor Resort and Marina

The Beach Club at Charleston Harbor Resort and Marina

The Beach Club at Charleston Harbor Resort and Marina
4.5 star property
Mount Pleasant
9.2 out of 10, Wonderful, (1005)
"Staff was courteous, hotel was beautiful."
United States
Johnna
The price is ₩171,563
₩263,997 total
includes taxes & fees
Dec 15 - Dec 16
The Beach Club at Charleston Harbor Resort and Marina
Lobby
The Francis Marion Hotel

The Francis Marion Hotel

The Francis Marion Hotel
4.0 star property
Charleston Historic District
9.0 out of 10, Wonderful, (1985)
"Nice ambiance and restaurant on site with love piano "
United States
Mila
The price is ₩211,460
₩241,059 total
includes taxes & fees
Jan 1 - Jan 2, 2026
The Francis Marion Hotel
Body treatments, hot stone massages, deep-tissue massages
Wild Dunes Resort – Residences at Sweetgrass

Wild Dunes Resort – Residences at Sweetgrass

Wild Dunes Resort – Residences at Sweetgrass
3.5 star property
Isle of Palms
8.6 out of 10, Excellent, (175)
"We come here often"
United States
Joseph
The price is ₩308,841
₩415,147 total
includes taxes & fees
Dec 15 - Dec 16
Wild Dunes Resort – Residences at Sweetgrass
Deep-tissue massages, Swedish massages, prenatal massages, massages
The Restoration

The Restoration

The Restoration
4.0 star property
Charleston Historic District
9.6 out of 10, Exceptional, (1004)
"Great place to stay for a few nights while visiting!"
United States
Kelly
The price is ₩348,444
₩409,477 total
includes taxes & fees
Jan 8 - Jan 9, 2026
The Restoration
Gift shop
Hotel Bennett

Hotel Bennett

Hotel Bennett
5.0 star property
Charleston Historic District
9.6 out of 10, Exceptional, (977)
"Great place to stay! Will definitely stay there again!"
United States
Leigh Regenold
The price is ₩589,606
₩675,520 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hotel Bennett
Couples treatment rooms, sauna, body treatments, hydrotherapy
The Charleston Place

The Charleston Place

The Charleston Place
5.0 star property
Charleston Historic District
9.6 out of 10, Exceptional, (1003)
"Staff was great, room perfect and we had a lovely time in Charleston!😊"
United States
Janis
The Charleston Place
Terrace/patio
The Pinch Hotel

The Pinch Hotel

The Pinch Hotel
4.0 star property
Charleston Historic District
9.8 out of 10, Exceptional, (171)
"Wonderful stay at The Pinch! The staff is lovely, friendly and helpful. They were able to offer us an upgrade, and the accommodations are well-designed with high-end finishes. Absolutely recommend! "
United States
Heather
The Pinch Hotel
Children's play area - outdoor
The Sanctuary at Kiawah Island Golf Resort

The Sanctuary at Kiawah Island Golf Resort

The Sanctuary at Kiawah Island Golf Resort
5.0 star property
East Beach
9.6 out of 10, Exceptional, (227)
"all was excellent."
United States
michael
The price is ₩428,536
₩484,245 total
includes taxes & fees
Dec 15 - Dec 16
The Sanctuary at Kiawah Island Golf Resort
Couples treatment rooms, body treatments, hot stone massages
The Dewberry Charleston

The Dewberry Charleston

The Dewberry Charleston
5.0 star property
Charleston Historic District
9.6 out of 10, Exceptional, (1000)
"Great stay, terrific room, superb location. Staff was efficient and very pleasant."
United States
William
The price is ₩545,275
₩624,984 total
includes taxes & fees
Jan 11 - Jan 12, 2026
The Dewberry Charleston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mount Pleasant Hotel Reviews

Harborside at Charleston Harbor Resort and Marina

Harborside at Charleston Harbor Resort and Marina

10/10 Excellent
"My son and I truly enjoyed spending Thanksgiving at Harbourside Charleston Marina & Resort. From the moment we arrived, everything felt welcoming and comfortable. Our hotel room was exceptionally clean and fresh, which made our stay even more relaxing. We’re already looking forward to returning during the warmer months so we can take advantage of more of the wonderful amenities this resort has to offer. Thank you to the staff and team for providing us with such a great experience!"
Winema 2-night trip
Posted 11 days ago
Harborside at Charleston Harbor Resort and Marina

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Frequently asked questions

Looking for a spa hotel in Mount Pleasant?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers highly recommend the restaurants in Mount Pleasant. Enjoy the historical sites and riverfront during your vacation. Hotels with spas are the perfect way to break out of your daily routine and add a layer of luxury to your vacation.
What is the best spa hotel in Mount Pleasant?
The Beach Club at Charleston Harbor Resort and Marina is a highly recommended beach spa hotel featuring a 24-hour fitness center and an outdoor pool. Treat yourself to a body wrap, couples treatments, or massage at Estuary Spa.
How many spa hotels will I find in Mount Pleasant?
Among Expedia's 373 accommodation options in Mount Pleasant, there is 1 spa hotel.
What's there to see and do in Mount Pleasant?
Experience Mount Pleasant with a stop at Mount Pleasant Towne Centre, Shem Creek Park, and Patriots Point. If you have a little extra time during your trip, you might want to check out USS Yorktown and Charleston Harbor Marina.
What is a Mount Pleasant spa hotel?
Spa hotels in Mount Pleasant provide lodging and have an on-site spa offering services including facials as well as beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.