The Best Resorts & Hotels with Spas in Mount Pleasant, SC from ₩318,289 in 2026

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Our top choices for Mount Pleasant hotels with a spa

Couples treatment rooms, hot stone massages, deep-tissue massages

Harborside at Charleston Harbor Resort and Marina

Mount Pleasant

Discover a waterfront wellness haven with tranquil spa treatments, couples massage rooms, and stunning sunset views from hot tubs.

₩318,289 total

includes taxes & fees

Jun 29 - Jun 30

2 outdoor pools, free cabanas, pool umbrellas

The Beach Club at Charleston Harbor Resort and Marina

Mount Pleasant

Retreat to this harborside haven with couples spa treatments and a heated pool, perfect for unwinding amid beautiful marina views.

₩440,787 total

includes taxes & fees

Jun 29 - Jun 30

Couples treatment rooms, sauna, steam room, body treatments

The Cooper

Charleston Historic District

₩1,646,549 total

includes taxes & fees

Jul 7 - Jul 8

The Dewberry Charleston

Charleston Historic District

Indulge in a tranquil spa retreat at this Charleston hotel where 5 treatment rooms offer deep-tissue massages and body wraps.

₩572,507 total

includes taxes & fees

Jun 28 - Jun 29

The Pinch Hotel

Charleston Historic District

Immerse in serene spa treatments at this Charleston hotel with couples' massage rooms and a cozy fireplace lobby.

₩532,960 total

includes taxes & fees

Jul 1 - Jul 2

Deep-tissue massages, Swedish massages, prenatal massages, massages

The Restoration

Charleston Historic District

Revitalize in Charleston with a rooftop pool, indulgent spa massages, and luxurious rooms featuring rainfall showers and plush bedding.

₩498,137 total

includes taxes & fees

Jun 29 - Jun 30

On the beach, sun loungers, beach umbrellas, beach towels

The Sanctuary at Kiawah Island Golf Resort

East Beach

Revitalize your spirit at this coastal sanctuary with beach yoga, massage treatments, and full-service spa facilities for ultimate wellness.

₩1,268,699 total

includes taxes & fees

Jun 30 - Jul 1

Hotel Bennett

Charleston Historic District

Relax in elegance at this Charleston hotel with a full-service spa, rooftop pool, and 5 treatment rooms.

₩831,951 total

includes taxes & fees

Jul 1 - Jul 2

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Choose what matters most at spa hotels in Mount Pleasant

Pool

Breakfast included

Top Mount Pleasant Hotel Reviews

Harborside at Charleston Harbor Resort and Marina

8/10 Good

"We enjoyed our stay. The place has a cool vibe. We liked the little beach area, pool and easy walk to the water taxi. Our room was nice enough. We had room 215 which was a “harbor view” room, we could see the next door beach club swimming pool. The beds were nice, I would’ve preferred less giant pillows and a couple of standard sized pillows. 6 lg pillows per queen sized bed is too many! I liked the bar and grill, nice staff and ok bar food. The hotel could use a few nice vending machines. The downside is that there is only 1 restaurant . The fish house, it has a magnificent view, but we were not impressed with the food. They did not have takeout. The free shuttle to downtown was nice. James should have been a tour guide!"

The Francis Marion Hotel

8/10 Good

"Hotel was absolutely BEAUTIFUL and in a great location. Any type of cuisine you could want is within a 10 minute walk along with lots of restaurants serving up local fare. Staff was super helpful and for a hotel that is over 100 years old, it was very well kept and clean. Only complaint is that beds are full size, not queen so be sure to pay close attention when booking. I did not and found it difficult for our party of 3 to sleep in only two beds. Staff was amazing about bringing in a twin size roll away when I asked for one... but it unfortunately was also very uncomfortable. And the Starbucks was closed. Those are my only complaints. Otherwise hotel was absolutely BEAUTIFUL and in a great location. We were only there for a weekend but we really enjoyed our stay in Charleston."

The Beach Club at Charleston Harbor Resort and Marina

10/10 Excellent

"Room was lovely with a balcony, though if possible ask for one that's not on the first floor, where what you see is the pool. The Harbor view from upper floors is beautiful. Daily resort fee covers the usual, but they also provide a free shuttle into town which was so worth it and ice cream treats daily."

Frequently asked questions

Looking for a spa hotel in Mount Pleasant?

Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers highly recommend the restaurants in Mount Pleasant. Enjoy the historical sites and riverfront during your vacation. Hotels with spas are the perfect way to break out of your daily routine and add a layer of luxury to your vacation.

What is the best spa hotel in Mount Pleasant?

The Beach Club at Charleston Harbor Resort and Marina is a top beach spa hotel featuring 3 bars, a 24-hour fitness center, and a restaurant. Treat yourself to a body wrap, couples treatments, or massage at Estuary Spa.

How many spa hotels will I find in Mount Pleasant?

Among Expedia's 393 accommodation options in Mount Pleasant, there is 1 spa hotel.

What's there to see and do in Mount Pleasant?

Experience Mount Pleasant with a stop at Mount Pleasant Towne Centre, Shem Creek Park, and Patriots Point. If you have a little extra time during your trip, you might want to check out USS Yorktown and Charleston Harbor Marina.

What is a Mount Pleasant spa hotel?

Spa hotels in Mount Pleasant provide lodging and have an on-site spa offering services including facials as well as beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.

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Change your mind

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Check availability on Mount Pleasant Resorts & Hotels with Spas

Our top choices for Mount Pleasant hotels with a spa

Harborside at Charleston Harbor Resort and Marina