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Our top choices for Northeast Missouri hotels

1. Pear Tree Inn St. Louis Airport

St. Ann

Darren

₩152,502 total

includes taxes & fees

Aug 16 - Aug 17

2. Drury Inn & Suites St. Louis Airport

Edmundson

Ryan

₩194,205 total

includes taxes & fees

Aug 16 - Aug 17

3. Hyatt Select St. Louis Airport

Woodson Terrace

badarinath

₩208,442 total

includes taxes & fees

Aug 31 - Sep 1

4. Wingate by Wyndham St. Louis Airport

St. Ann

Gregory

₩198,275 total

includes taxes & fees

Sep 2 - Sep 3

5. Oak Hill Inn & Suites

Canton

Mary

₩166,084 total

includes taxes & fees

Aug 10 - Aug 11

6. The Wildwood Hotel

Wildwood

Hailey

₩147,881 total

includes taxes & fees

Aug 24 - Aug 25

7. Best Western St. Louis Inn

St. Louis

Garland

₩140,696 total

includes taxes & fees

Aug 10 - Aug 11

8. Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Fenton

Allison

₩156,831 total

includes taxes & fees

Aug 3 - Aug 4

9. Renaissance St. Louis Airport Hotel

Berkeley

Ryan

₩200,378 total

includes taxes & fees

Aug 23 - Aug 24

Desk, blackout drapes, iron/ironing board, WiFi (free)

10. Town & Country Inn and Suites

Quincy

Tracy

₩220,003 total

includes taxes & fees

Aug 3 - Aug 4

11. Pear Tree Inn St. Louis Arnold

Arnold

Phillip

₩149,733 total

includes taxes & fees

Aug 13 - Aug 14

12. Drury Inn & Suites Southwest St. Louis

Valley Park

Larry

₩215,517 total

includes taxes & fees

Sep 1 - Sep 2

13. Best Western Plus Washington Hotel

Washington

Zackariah

₩211,390 total

includes taxes & fees

Aug 3 - Aug 4

5 restaurants; breakfast, lunch, dinner, and brunch served

14. River City Casino & Hotel

St. Louis

jason

₩201,910 total

includes taxes & fees

Aug 12 - Aug 13

15. Drury Plaza Hotel St. Louis Chesterfield

Chesterfield

Madeleine

₩217,012 total

includes taxes & fees

Aug 30 - Aug 31

16. Hampton Inn Kirksville

Kirksville

Thomas

₩199,291 total

includes taxes & fees

Aug 9 - Aug 10

Desk, iron/ironing board, WiFi (surcharge), bed sheets

17. Best Western On The River

Hannibal

Carolyn

₩212,504 total

includes taxes & fees

Aug 5 - Aug 6

18. Holiday Inn Express & Suites St Louis Airport by IHG

Woodson Terrace

Valerie

₩213,596 total

includes taxes & fees

Aug 30 - Aug 31

19. Comfort Inn Sullivan

Sullivan

Stephanie

₩199,986 total

includes taxes & fees

Aug 30 - Aug 31

20. Heritage Hotel Quincy

Quincy

Dustine

₩114,989 total

includes taxes & fees

Aug 3 - Aug 4

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Vacation Rentals in Northeast Missouri

Cabin

Cannon Dam Cabins

Perry

"Cozy and well equipped with everything we may have needed"

Aparthotel

Comfort Loft, 2 Queen Beds, Bathtub, Garden View | Living area | 45-inch Smart TV with digital channels, books, streaming services

The Mercantile on the Katy Trail

Hermann

"It’s an absolute must do! Such a cool little town right on the Katy Trail!"

Cottage

Walk to Tower Grove Park: St Louis Getaway

Tower Grove South

"great place and nice location"

Vacation Home

Remodeled and Inviting Free EV

Fenton

"The property was excellent, and the home was very warm and welcoming."

Apartment

Near Wineries: Country Condo in New Haven

New Haven

"Clean and loved original architecture."

Cottage

Peaceful Missouri Cabin Rental on 55 Acres!

Canton

"This is a great place to stay if you want to get away from the city. Rural enough to be quiet, but within easy driving distance to a city. Also perfect if you just want to stay on the property and really get away from city life, just bring your groceries. "

Apartment

Lakefront Studio Guest Home on Hermann Wine Trail!

New Haven

"Loved this property, very clean and well kept! Very pretty, lovely view. "

Cottage

Spacious Owensville Getaway w/ Winery On-site!

Rosebud

"I don't even know where to start with this rental. We live in the country, this farmhouse was right up our alley!! I have stayed in a lot of rental properties, this one was like being at home. I could have stayed forever. The pond served as a wonderful experience for my daughter, she loves to fish and caught many fish. My husband enjoyed watching the sunrise every morning with his cup of coffee. The restaurant was in a league of it's own, the food was spectacular. The owner was VERY responsive,...

Cottage

Updated Missouri Cabin Rental on Large Farm

Canton

"The cabin rental was a great stay. Had some connection problems with the t.v. couldn't get past the check out date. The wifi was easy to hook up. The cabin was clean and smelled fresh. Did have some problems with ants on the countertop. Great place to stay, enjoyed our visit."

Cottage

Home w/ Trail Access on 19 Acres in Wright City!

Wright City

"Great house in a beautiful setting. We enjoyed the quiet solitude and woodsy area. Very clean accommodations with every amenity available. "

Apartment

St Louis Retreat ~ 1 Mi to Botanical Garden

Shaw

"Clean, private, Easy check-in and out."

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Stay near popular Northeast Missouri attractions

A cityscape with a prominent arch structure, various high-rise buildings, and a large government building.

Dome at America’s Center

8.4/10 (1,229 reviews)

Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's acclaimed art scene and great live music.

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Learn more about Northeast Missouri

Great live music, sports teams, and popular sights from St. Louis Union Station to Dome at America’s Center—explore Northeast Missouri, a family-friendly destination also known for its theaters.

See all hotels in Northeast Missouri

A historic log cabin with a flagpole, hay bales, and autumn pumpkins.

Top Northeast Missouri Hotel Reviews

Moonrise Hotel

10/10 Excellent

"My stay was lovely, would definitely come again. :)"

Clayton Plaza Hotel & Extended Stay

8/10 Good

"The elevators were broken and there was a pail to catch leaking water nearby them . Breakfast was fine but I find the need to be seated by a server for a buffet ,( yet you’re getting your own drinks and food )is just a bit bizarre . Tip: get a freshly prepared omelet , because other wise there is no cheese or fresh veggies offered at the buffet . Overall I think it’s a safe area to stay and it wasn’t awful. Beds not too comfy and room is a bit dated . (Remote wouldn’t work ) . I called the front desk to see if they could switch out the remote. They said they would send someone up but they never came . It’s tough to have a tv on and you can’t change the channel . Pointless . Popcorn ceilings . Expensive vending machine and no complimentary water /water bottle ."