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Go beyond your typical stay in Northeast Missouri

Spa

Waterpark

Our top choices for Northeast Missouri hotels

Pear Tree Inn St. Louis Airport

St. Ann

Gary

₩180,999 total

includes taxes & fees

Aug 2 - Aug 3

Wingate by Wyndham St. Louis Airport

St. Ann

Irmaris

₩207,724 total

includes taxes & fees

Jul 12 - Jul 13

Drury Inn & Suites St. Louis Airport

Edmundson

Dana

₩230,896 total

includes taxes & fees

Jul 20 - Jul 21

Hyatt Select St. Louis Airport

Woodson Terrace

Andrew

₩207,974 total

includes taxes & fees

Aug 2 - Aug 3

Best Western St. Louis Inn

St. Louis

Hamdija

₩127,285 total

includes taxes & fees

Jul 8 - Jul 9

Oak Hill Inn & Suites

Canton

Kaia

₩177,405 total

includes taxes & fees

Jul 11 - Jul 12

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Fenton

Trevor

₩167,520 total

includes taxes & fees

Jul 5 - Jul 6

The Wildwood Hotel

Wildwood

Lori

₩174,079 total

includes taxes & fees

Jul 20 - Jul 21

Hollywood Casino & Hotel St. Louis

Riverport

Elaina

₩202,224 total

includes taxes & fees

Jul 8 - Jul 9

Baymont by Wyndham Warrenton

Warrenton

Steven

₩143,459 total

includes taxes & fees

Jul 12 - Jul 13

Pear Tree Inn St. Louis Arnold

Arnold

Eliza

₩176,805 total

includes taxes & fees

Jul 13 - Jul 14

Hampton Inn By Hilton St Louis Airport

Woodson Terrace

Alana

₩262,554 total

includes taxes & fees

Jul 22 - Jul 23

Drury Inn & Suites Southwest St. Louis

Valley Park

Sophia

₩230,207 total

includes taxes & fees

Jul 19 - Jul 20

Renaissance St. Louis Airport Hotel

Berkeley

James

₩228,425 total

includes taxes & fees

Jul 17 - Jul 18

Desk, iron/ironing board, WiFi, bed sheets

Best Western On The River

Hannibal

Christina

₩208,899 total

includes taxes & fees

Jul 13 - Jul 14

Desk, blackout drapes, iron/ironing board, free WiFi

Town & Country Inn and Suites

Quincy

David

₩235,001 total

includes taxes & fees

Jul 6 - Jul 7

Drury Plaza Hotel St. Louis Chesterfield

Chesterfield

Jessica

₩242,506 total

includes taxes & fees

Jul 20 - Jul 21

Holiday Inn Express & Suites St Louis Airport by IHG

Woodson Terrace

Tyree

₩228,173 total

includes taxes & fees

Jul 26 - Jul 27

Clayton Plaza Hotel & Extended Stay

Clayton

RAJA

₩173,686 total

includes taxes & fees

Jul 12 - Jul 13

5 restaurants; breakfast, lunch, dinner, and brunch served

River City Casino & Hotel

St. Louis

Austin

₩194,150 total

includes taxes & fees

Jul 13 - Jul 14

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Vacation Rentals in Northeast Missouri

Aparthotel

Down comforters, blackout drapes, iron/ironing board, free WiFi

Lighthouse Inn & Suites

Hannibal

"Fun themed rooms."

Apartment

White House at Grand Central

Grand Center

"The space was very clean, cozy and quiet. There was plenty of room to be comfortable to both rest and have time to get work done or relax in the living room area. The location was very convenient for everything we were visiting St Louis for! (We could walk to both the Fabulous Fox Theatre and Foundry - about 15 min each, and it was a very short trip to the Enterprise Center)"

Apartment

Near Wineries: Country Condo in New Haven

New Haven

"Clean and loved original architecture."

Cottage

Spacious Owensville Getaway w/ Winery On-site!

Rosebud

"I don't even know where to start with this rental. We live in the country, this farmhouse was right up our alley!! I have stayed in a lot of rental properties, this one was like being at home. I could have stayed forever. The pond served as a wonderful experience for my daughter, she loves to fish and caught many fish. My husband enjoyed watching the sunrise every morning with his cup of coffee. The restaurant was in a league of it's own, the food was spectacular. The owner was VERY responsive,...

Apartment

Charming Berger Apt on 42-acre Farm w/ Pool Access

Berger

Cottage

Peaceful Missouri Cabin Rental on 55 Acres!

Canton

"This is a great place to stay if you want to get away from the city. Rural enough to be quiet, but within easy driving distance to a city. Also perfect if you just want to stay on the property and really get away from city life, just bring your groceries. "

Apartment

Walk to Carondelet Park: Quiet Couple's Getaway

Carondelet

"We had a nice stay, close to things we wanted to do"

Cottage

Updated Missouri Cabin Rental on Large Farm

Canton

"The cabin rental was a great stay. Had some connection problems with the t.v. couldn't get past the check out date. The wifi was easy to hook up. The cabin was clean and smelled fresh. Did have some problems with ants on the countertop. Great place to stay, enjoyed our visit."

Cottage

Peaceful Guest Home w/ Patio on 152-acre Farm

Berger

"Very clean,family friendly, even though it was 7 miles out of town they were very Accommodating,they came to puck us up at the train station and there's a van that will take you into town and you can take the trolley to all the wineries,shopping, we all loved our stay,i would definitely recommend to anyone who enjoys the fram life, they have lots of history, and animals, thank you Susan and Mike for all that you did to make our stay memorable, we would definitely come back. "

Cottage

Hillside Cabin on 43 Acres w/ Private Lake & View!

Defiance

"We had a wonderful stay. The property is beautiful and well maintained, and the cabin is cute, comfortable, and well equipped. Nick is a very courteous host. We couldn’t have hoped for a better Thanksgiving getaway!"

Apartment

New Melle Apartment Near Missouri Wine Country

Wentzville

"Apartment was wonderful! Very spacious and lots of furniture. Had a flat screen in the living room and bedroom that included Netflix and Prime. Air conditioner worked very well. Was very quiet and in a good location. Property manager was very friendly. There was even a very nice tea selection included with our stay. All amenities including, fridge, sinks, countertop burner, shower, washer, dryer, and toilet worked with no issues. All the dishes and mugs were clean. Plenty of towels to use during...

Apartment

'the Ruebling House' Historic Defiance Apartment!

Defiance

"This was are first family Vacation and are stay was amazing nice and clean with plenty of space. I would definitely recommend to a friend."

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Stay near popular Northeast Missouri attractions

A baseball stadium with a large crowd, a prominent arch structure, and various advertisements.

Busch Stadium

9.4/10 (4,850 reviews)

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.

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Learn more about Northeast Missouri

Great live music, sports teams, and popular sights from St. Louis Zoo to St. Louis Union Station—explore Northeast Missouri, a family-friendly destination also known for its theaters.

See all hotels in Northeast Missouri

A historic log cabin with a flagpole, hay bales, and autumn pumpkins.

Top Northeast Missouri Hotel Reviews

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent

"Love the location and the fact that the hotel itself is located in a historic building. I appreciate the front desk staff being understanding of the fact we had a roof rack with a cargo management system on our vehicle, and allowed me to park in a spot not marked as a proper parking spot due to clearance in the garage."

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

8/10 Good

"Place was clean and rooms were good. Not fancy, but just a solid place to stay. There were a number of kids staying there with teams or families, but they were surprisingly good and did not stay up late. Nice breakfast. Good location for what I needed for my stay. Just off the highway 44. Indoor Jacuzzi was nice."

River City Casino & Hotel

8/10 Good

"Amenities were extra. We had to pay $14.95 when checking in. Rooms still have fluorescent bulbs! If, like me, they induce migraines for you, you will be forced to spend the evening in the dark when night falls. Hotel staff were incredible. Check in and out was very pleasant. Rooms were clean, and beds were comfy. Walls a little thin, but that's the only drawback. We walked through the casino on our way to dinner. Smoking is still out in the open, so if that's a concern for you, just be aware before walking through there. I don't know if smoking is allowed in the rooms, but ours had not been smoked in. Smelled fine."