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Oct 14 - Oct 15
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Oct 15 - Oct 16
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Oct 16 - Oct 18
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Oct 23 - Oct 25

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Our top choices for Puxico hotels

A modern hotel lobby with a bar area, seating, and artwork on the walls.
A modern hotel with a prominent sign, a covered entrance, and a well-lit exterior.
A swimming pool with clear blue water, surrounded by sun loungers and a lifeguard stand.
A reception desk with a wooden panel design, a white vase with flowers, and a 'Hilton HONOR' sign.

1. Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
Dexter
United States
Bryan
₩130,250
₩147,558 total
includes taxes & fees
Oct 25 - Oct 26
Hampton Inn By Hilton Dexter
A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.
A corner market with a refrigerated display case and a pantry area.
A reception desk with a bicycle light, potted plants, and a 'Connect & Print' sign.
An outdoor patio with a table and chairs, a large umbrella, and a glass door leading to an interior space.

2. Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
Poplar Bluff
United States
Nancy
₩130,209
₩147,103 total
includes taxes & fees
Nov 9 - Nov 10
Fairfield Inn & Suites by Marriott Poplar Bluff
A spacious lobby with a reception desk, seating area, and large windows.
A hotel room with a bed, a desk, a chair, a sofa, and a TV.
An indoor swimming pool with a clear view of the outside through large windows.
A spacious conference room with brick walls, multiple tables and chairs, a large window, and a mounted TV.

3. Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
Poplar Bluff
United States
Dean
₩125,458
₩141,735 total
includes taxes & fees
Oct 18 - Oct 19
Drury Inn & Suites Poplar Bluff
A hotel room with two beds, a nightstand, and a wall-mounted light fixture.
A hotel room with a flat-screen TV, a desk with a chair, a sofa, a small table, and framed pictures on the wall.
A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.
Terrace/patio

4. Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
Poplar Bluff
United States
Rhonda
₩121,400
₩135,937 total
includes taxes & fees
Nov 1 - Nov 2
Hampton Inn Poplar Bluff
A diner with booth seating, a checkered floor, and a counter with a cash register.
A lobby with a round rug, two potted plants, three framed artworks, and two black leather chairs.
A hotel room with a bed, a desk, a chair, a large mirror, a sink, and a trash bin.
A gym with multiple exercise machines, a clock on the wall, and a window with blinds.

5. Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
Dexter
United States
Steven
₩114,125
₩129,291 total
includes taxes & fees
Nov 1 - Nov 2
Travelodge by Wyndham Dexter
A hotel room with a sofa, a small table, a chair, a desk, two lamps, a window with curtains, and a framed picture on the wall.
A hotel lobby with a reception desk, seating area, and a television screen.
A hotel room with a desk, chair, and a small seating area. It includes a microwave, coffee maker, and a refrigerator.
A snack vending machine and shelves stocked with various snacks and beverages.

6. Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
Poplar Bluff
United States
Nathan
₩112,123
₩126,670 total
includes taxes & fees
Oct 18 - Oct 19
Holiday Inn Poplar Bluff by IHG
A coffee shop with a coffee machine, espresso cups, a sink, and a trash bin.
A hotel lobby with a reception desk, a waiting area with a sofa and armchairs, and a patterned carpet.
A hotel hallway with patterned carpet, light green walls, and a ceiling with recessed lighting.
A kitchen with a white microwave, a fruit basket, a coffee maker, and a storage container.

7. Dexter Inn

Dexter Inn
Dexter
United States
Edward
₩92,101
₩104,339 total
includes taxes & fees
Oct 15 - Oct 16
Dexter Inn
A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.
A hotel room with two beds, a desk, a chair, a TV mounted on the wall, and a mirror.
A motel with a prominent '66' sign, large windows, and a flat roof.
A compact kitchen with a dark wooden desk, a black refrigerator, a microwave, and a coffee maker.

8. Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
Poplar Bluff
United States
Cindy
₩94,904
₩106,263 total
includes taxes & fees
Oct 27 - Oct 28
Motel 6 Poplar Bluff, MO
A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a patterned floor.
A living room with a sofa, a coffee table, a clock, and a painting on the wall.
A hotel with a brick facade, multiple windows, and a covered entrance area.
A kitchen with wooden cabinets, a stainless steel sink, a microwave, and a dishwasher.

9. Econo Lodge Dexter

Econo Lodge Dexter
Dexter
United States
Herman
₩68,061
₩77,105 total
includes taxes & fees
Nov 12 - Nov 13
Econo Lodge Dexter
A hotel room with two beds, a TV, a mirror, a wardrobe, and a desk.
A bathroom with a bathtub, toilet, and a shower curtain.
A Hickory House Inn with a clear sky, a parking lot, and a covered entrance.
A window with a view of a parking lot and buildings, a welcome sign, and a credit card machine.

10. OYO Hickory House Inn

OYO Hickory House Inn
Dexter
United States
DIEGO
₩73,574
₩90,699 total
includes taxes & fees
Oct 27 - Oct 28
OYO Hickory House Inn
A hotel lobby with a reception desk, a blue sofa, a fireplace, and a television.
A hotel lobby with a coffee station, seating area, and a television screen.
A hotel with a covered entrance, multiple windows, and a yellow facade.
A hotel room with a bed, a sofa, a small table, and a painting on the wall.

11. Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North
Poplar Bluff
United States
Muhammad
₩100,083
₩113,069 total
includes taxes & fees
Nov 8 - Nov 9
Comfort Inn Poplar Bluff North
A hotel room with a bed, two bedside lamps, a framed picture of a building, and a nightstand with a phone.
A lobby with a reception desk, a Coca-Cola vending machine, a snack vending machine, and a seating area with a round table.
A laundry area with two stacked washers and dryers, a control panel, and a beige wall with a wooden panel above the dryers.
A self-service breakfast area with a refrigerated drink cooler, a coffee machine, and various food items on the counter.

12. Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri
Poplar Bluff
United States
Diana
₩89,632
₩101,261 total
includes taxes & fees
Oct 20 - Oct 21
Super 8 by Wyndham Poplar Bluff Missouri
A rustic cabin with a metal roof, surrounded by a wooden deck and picnic tables, set in a forested area.
A wooden deck with a railing leading to a building with a metal roof and a brown door.
A bedroom with a wooden bed, a bench, and a window.
Front of property

13. Lake Wappapello

Lake Wappapello
Williamsville
United States
Tonya
₩120,132
₩126,709 total
includes taxes & fees
Oct 16 - Oct 17
Lake Wappapello
A living room with a blue wall, a fireplace, a sofa, and a chair.
A hotel room with two beds, a vanity with a mirror, a chair, and a dresser.
A brick building with a sign reading "Mercantile & Hotel".
A bar area with stools and a counter where a bartender is serving drinks.

14. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
Marble Hill
United States
Miranda
₩141,279
₩153,782 total
includes taxes & fees
Oct 15 - Oct 16
EC Reed's Mercantile and Hotel
A spacious living area with a dark grey sofa set, a matching ottoman, and a wooden-paneled wall.
A house with a red door, a porch with rocking chairs, and a wreath on the door.
A two-story house with a deck and a covered porch.
A spacious dining area with a stone wall, wooden furniture, and a fireplace.

15. 40-acre Poplar Bluff Nature Lovers Paradise!

40-acre Poplar Bluff Nature Lovers Paradise!
Poplar Bluff
United States
Anonymous traveler
₩161,250
₩398,946 total
includes taxes & fees
Oct 21 - Oct 22
40-acre Poplar Bluff Nature Lovers Paradise!
View all properties

Hotels recommended for families in Puxico

A modern hotel lobby with a bar area, seating, and artwork on the walls.
A modern hotel with a prominent sign, a covered entrance, and a well-lit exterior.
A swimming pool with clear blue water, surrounded by sun loungers and a lifeguard stand.
A reception desk with a wooden panel design, a white vase with flowers, and a 'Hilton HONOR' sign.

Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
Dexter
₩130,250
₩147,558 total
includes taxes & fees
Oct 25 - Oct 26
Hampton Inn By Hilton Dexter
A spacious lobby with a reception desk, seating area, and large windows.
A hotel room with a bed, a desk, a chair, a sofa, and a TV.
An indoor swimming pool with a clear view of the outside through large windows.
A spacious conference room with brick walls, multiple tables and chairs, a large window, and a mounted TV.

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
Poplar Bluff
₩125,458
₩141,735 total
includes taxes & fees
Oct 18 - Oct 19
Drury Inn & Suites Poplar Bluff
A hotel room with two beds, a nightstand, and a wall-mounted light fixture.
A hotel room with a flat-screen TV, a desk with a chair, a sofa, a small table, and framed pictures on the wall.
A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.
Terrace/patio

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
Poplar Bluff
₩121,400
₩135,937 total
includes taxes & fees
Nov 1 - Nov 2
Hampton Inn Poplar Bluff
A diner with booth seating, a checkered floor, and a counter with a cash register.
A lobby with a round rug, two potted plants, three framed artworks, and two black leather chairs.
A hotel room with a bed, a desk, a chair, a large mirror, a sink, and a trash bin.
A gym with multiple exercise machines, a clock on the wall, and a window with blinds.

Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
Dexter
₩114,125
₩129,291 total
includes taxes & fees
Nov 1 - Nov 2
Travelodge by Wyndham Dexter
A coffee shop with a coffee machine, espresso cups, a sink, and a trash bin.
A hotel lobby with a reception desk, a waiting area with a sofa and armchairs, and a patterned carpet.
A hotel hallway with patterned carpet, light green walls, and a ceiling with recessed lighting.
A kitchen with a white microwave, a fruit basket, a coffee maker, and a storage container.

Dexter Inn

Dexter Inn
Dexter
₩92,101
₩104,339 total
includes taxes & fees
Oct 15 - Oct 16
Dexter Inn
A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.
A corner market with a refrigerated display case and a pantry area.
A reception desk with a bicycle light, potted plants, and a 'Connect & Print' sign.
An outdoor patio with a table and chairs, a large umbrella, and a glass door leading to an interior space.

Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
Poplar Bluff
₩130,209
₩147,103 total
includes taxes & fees
Nov 9 - Nov 10
Fairfield Inn & Suites by Marriott Poplar Bluff
A hotel room with a sofa, a small table, a chair, a desk, two lamps, a window with curtains, and a framed picture on the wall.
A hotel lobby with a reception desk, seating area, and a television screen.
A hotel room with a desk, chair, and a small seating area. It includes a microwave, coffee maker, and a refrigerator.
A snack vending machine and shelves stocked with various snacks and beverages.

Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
Poplar Bluff
₩112,123
₩126,670 total
includes taxes & fees
Oct 18 - Oct 19
Holiday Inn Poplar Bluff by IHG
A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.
A hotel room with two beds, a desk, a chair, a TV mounted on the wall, and a mirror.
A motel with a prominent '66' sign, large windows, and a flat roof.
A compact kitchen with a dark wooden desk, a black refrigerator, a microwave, and a coffee maker.

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
Poplar Bluff
₩94,904
₩106,263 total
includes taxes & fees
Oct 27 - Oct 28
Motel 6 Poplar Bluff, MO
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Learn more about Puxico

Check out the local area in Puxico—home to attractions like Mark Twain National Forest and Mingo Wilderness.

See all hotels in Puxico
A night scene with a clear sky, a crescent moon, and two silhouetted trees against a twilight sky.
Photo by Mike McClain

Top Puxico Hotel Reviews

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

8/10 Good
"Our room was fine with new appliances. Creepy tv logo features your name. We did find the elevators were slow and noisy to the 4th floor. The pool was clean but not very big or deep. The gym was fine with satelite tv but there was a broken mirror. There was a 25$ charge when you walk in the door. I was not notified about. I had already paided for hotel insurance. Brrakfast was provided and okay. Uppers floors hallways were being humidfied and hot fans going."
Ashley 1-night trip
Posted 8 hours ago
Hampton Inn Poplar Bluff
Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG

8/10 Good
"Beds were ok. Could be updated, little hard but slept ok. AC was loins in our particular room. Told front desk n said they would be sure to have it looked at. The suite was incredible large."
Linda I 2-night trip
Posted 2 days ago
Holiday Inn Poplar Bluff by IHG
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

8/10 Good
"I only stayed here from midnight until 5:30. It was clean, however the bed was very thin and uncomfortable and the heat/ac didn't work correctly which happens sometimes. The thermostat said 75 and it was freezing. It was a good place to crash for a few hours."
Charles 1-night trip
Posted 3 days ago
Motel 6 Poplar Bluff, MO
EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel

10/10 Excellent
"On street parking, quiet little town, absolutely beautiful little hotel, diner, and general store. Very unique! It’s a whole experience staying here. I would love an opportunity to stop here again if I’m ever going through this area again."
Miranda 1-night trip
Posted 4 days ago
EC Reed's Mercantile and Hotel
Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

10/10 Excellent
"This place is Brand new and really great!"
Bryan 1-night trip
Posted 5 days ago
Hampton Inn By Hilton Dexter
Lake Wappapello

Lake Wappapello

10/10 Excellent
"This a cabin in a state park. It was very clean and had newer upgrades. Bring the food you need because it's fairly distance from a grocery. We came later in the day because we needed one night and this was a great price and not a chain hotel which we like. There is a little store not too far from the park. We ordered deli sandwiches from here and picked up some icecream. The sandwiches were delicious and the store had pretty much whatever you might need. The checkin process was great with good communication about which cabin to go to, what the door code was etc... We plan to come back for a longer stay so we can have another evening around the firepit and see all of the stars. Great place to stay."
Dottie 1-night trip
Posted 1 month ago
Lake Wappapello

More cheap stays in Puxico

Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri

2831 N Westwood Blvd Poplar Bluff MO
₩89,632
₩101,261 total
Oct 20 - Oct 21
includes taxes & fees
Super 8 by Wyndham Poplar Bluff Missouri
Dexter Inn

Dexter Inn

1807 W Business US Highway 60 Dexter MO
₩92,101
₩104,339 total
Oct 15 - Oct 16
includes taxes & fees
Dexter Inn
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

4101 Highway 67 N Poplar Bluff MO
₩94,904
₩106,263 total
Oct 27 - Oct 28
includes taxes & fees
8/10 Very Good! (1,000 reviews)
Motel 6 Poplar Bluff, MO
Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North

2582 N Westwood Blvd Poplar Bluff MO
₩100,083
₩113,069 total
Nov 8 - Nov 9
includes taxes & fees
Comfort Inn Poplar Bluff North
Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

2420 Crestwood Dr Poplar Bluff MO
₩121,400
₩135,937 total
Nov 1 - Nov 2
includes taxes & fees
9.4/10 Exceptional! (984 reviews)
Hampton Inn Poplar Bluff
Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

2179 Gill Plaza Drive Dexter MO
₩130,250
₩147,558 total
Oct 25 - Oct 26
includes taxes & fees
9.6/10 Exceptional! (78 reviews)
Hampton Inn By Hilton Dexter

Frequently asked questions

What's the best place for a stay in Puxico?
Holiday Inn Poplar Bluff by IHG, located 18.8 mi (30.3 km) from the heart of Puxico, is a top choice for your stay based on our traveler data. Two other choices for your trip to the area are Hampton Inn Poplar Bluff and Motel 6 Poplar Bluff, MO. See all available top hotels, or vacation rentals in Puxico.
If I need to cancel my hotel reservation in Puxico, will I receive a refund?
Yes, you'll find most hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Puxico.
Where can I learn more about changing or cancelling my trip to Puxico?
To find more details about picking new dates or cancelling your trip to Puxico, click here.
What is staying in Puxico like?
Travelers to Puxico will find plenty to explore and enjoy. There are 52 hotels and other accommodations in the surrounding area. Find out more about Puxico.
What is there to see in Puxico?
A couple of favorite places to visit are Mark Twain National Forest and Mingo Wilderness. You'll also find Lake Wappapello and Lake Wappapello State Park in the area. Check out what more to see and do in Expedia's Puxico guide.
What's the seasonal weather like in Puxico?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Puxico is 59 inches.

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