Find hotels in Santee, NE from ₩167,423

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Compare 59 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santee

Head to sights like Lewis and Clark Lake as you discover the local area in Santee.

Top Santee Hotel Reviews

Frequently asked questions

If I need to cancel my hotel reservation in Santee, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable as long as you cancel before the hotel’s cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santee.

Where can I learn more about changing or cancelling my trip to Santee?

For more information about rescheduling or cancelling your trip to Santee, click here.

What are some hotels with pools in Santee?

Lewis and Clark Resort: Features free parking, an outdoor pool, and free WiFi. View all hotels with pools in Santee.

What is staying in Santee like?

Those traveling to Santee are sure to enjoy the sights to see and things to do. There are 59 hotels and other accommodations in the surrounding area. Find out more about Santee.

What are the top places to visit in Santee?

A favorite place to visit is Lewis and Clark Lake. You'll also find Niobrara State Park and Lewis and Clark Recreation Area in the area. Check out what more to see and do in Expedia's Santee guide.

What's the weather like in Santee?

The hottest months are usually July and August with an average temp of 72°F, while the coldest months are January and February with an average of 26°F. The snowiest months in Santee are January, December, October, and March, with each month seeing an average of 8 inches of snowfall.