The Best Business Hotels in Southeast Iowa from ₩118,939 in 2026

A paved courtyard with a brick pathway, trees, and a distant view of a road and buildings.

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Our top choices for Southeast Iowa business-friendly hotels

Family Suite, Multiple Beds | Premium bedding, down comforters, in-room safe, desk

1. Cobblestone Inn & Suites - Fort Madison

Fort Madison

Elaine

₩129,477

₩145,014 total

includes taxes & fees

Sep 17 - Sep 18

Indoor pool, open 7 AM to 10 PM, pool umbrellas

Suite, 1 King Bed with Sofa bed, Accessible, Non Smoking (Accesible Tub) | Premium bedding, desk, laptop workspace, iron/ironing board

2. Quality Inn & Suites Fort Madison near Hwy 61

Fort Madison

Cheyenne

₩117,469

₩131,566 total

includes taxes & fees

Sep 27 - Sep 28

Desk, blackout drapes, iron/ironing board, cribs (free)

3. AmericInn by Wyndham Mount Pleasant

Mount Pleasant

Terri

₩114,701

₩128,465 total

includes taxes & fees

Sep 27 - Sep 28

Desk, iron/ironing board, WiFi (free), bed sheets

4. Best Western Mt. Pleasant Inn

Mount Pleasant

Anthony

₩106,196

₩118,939 total

includes taxes & fees

Sep 27 - Sep 28

Double Room, 2 Double Beds | Pillowtop beds, desk, laptop workspace, blackout drapes

Combined shower/tub, free toiletries, hair dryer, towels

5. Super 8 by Wyndham Mt Pleasant

Mount Pleasant

frank

₩115,860

₩129,763 total

includes taxes & fees

Sep 17 - Sep 18

Room, Multiple Beds, Non Smoking, Kitchenette | Desk, laptop workspace, iron/ironing board, WiFi (free)

6. Nauvoo Vacation Villas & Condos

Nauvoo

Renae

₩196,281

₩208,017 total

includes taxes & fees

Sep 21 - Sep 22

Indoor pool, open 7:00 AM to 11:00 PM, sun loungers

Suite, 1 King Bed with Sofa bed, Non Smoking | In-room safe, desk, iron/ironing board, cribs (free)

7. Quality Inn & Suites Keokuk North

Keokuk

Susan

₩150,073

₩168,093 total

includes taxes & fees

Sep 27 - Sep 28

Indoor pool, open 6 AM to 11 PM, sun loungers

8. Hampton Inn Keokuk

Keokuk

Kristopher

₩148,723

₩166,571 total

includes taxes & fees

Oct 10 - Oct 11

View all properties

Top Southeast Iowa Hotel Reviews

Best Western Mt. Pleasant Inn

10/10 Excellent

"It was well taken care of, the staff were friendly and helpful. There were shops close by and it was close to the highway for easy access to get back home."

Fun City Resort Hotel

8/10 Good

"Fun experience, dining, casino, pool and arcade all in one!"

Quality Inn & Suites Keokuk North

10/10 Excellent

"Excellent place to stay. Location was perfect and a lot cheaper than the Hampton."

Quality Inn & Suites Mount Pleasant

10/10 Excellent

"The room did feel a little damp and smelled a little musty. Other than that, everything was great!"

Comfort Suites Burlington

8/10 Good

"Rooms were clean, the lady at desk when we checked in wasn't very friendly and didn't greet us or acknowledge us until she finished texting on her phone which was about 5 to 10min."

Baymont by Wyndham Keokuk

8/10 Good

"Pool was closed"

Frequently asked questions

How much do business-friendly hotels in Southeast Iowa cost?

Expect to pay between ₩118,939 and ₩219,819 per night for business-friendly hotels in Southeast Iowa. Awesome deals on stays that are suitable for corporate travelers are a click away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

How many business-friendly hotels are there in Southeast Iowa?

Southeast Iowa has 17 business-friendly hotels to choose from. Whether you're attending a conference or working remotely, these properties are equipped with everything you need to be productive.

Why book your business-friendly hotel in Southeast Iowa with Expedia?

Expedia will help you find a fabulous business-friendly hotel when work takes you on the road. From free WiFi and parking to gyms and spas, our stays come with all you'll need to settle that big contract.

How can I find cheap business-friendly hotels in Southeast Iowa?

Expedia can help you easily find cheap business-friendly hotels in Southeast Iowa. Simply head to the "traveler experience" filter and click on "business friendly." This will show you properties with amenities designed to help you work comfortably and efficiently, like included breakfast and free WiFi. You can also choose your hotel star rating and budget to keep costs down.

What is there to do in Southeast Iowa near my business-friendly hotel?

You'll find tons of attractions to see during your time in Southeast Iowa. If you've planned a couple of nights in Nauvoo, Rheinberger House Museum is a must-see.

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Change your mind

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Check availability on Southeast Iowa Business Hotels

Our top choices for Southeast Iowa business-friendly hotels

1. Cobblestone Inn & Suites - Fort Madison