The Best Business Hotels in Southeast Iowa from ₩117,407 in 2026

A paved courtyard with a brick pathway, trees, and a distant view of a road and buildings.

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Our top choices for Southeast Iowa business-friendly hotels

A lobby with a stone fireplace, comfortable seating, and a flat-screen TV mounted on the wall.

A fire pit surrounded by outdoor furniture, including a sofa and chairs, in a patio area.

A reception area with a reception desk, a plant, and a sign for Boulders Inn & Suites.

A hotel room with two beds, a television, a desk with a lamp, and a chair.

1. Cobblestone Inn & Suites - Fort Madison

Fort Madison

Elaine

₩204,503

₩229,045 total

includes taxes & fees

Sep 22 - Sep 23

A spacious living area with a wooden staircase, a stone fireplace, and a reception desk.

A reception area with a stone wall, wooden reception desk, and a sign that reads "Quality".

A hotel room with two beds, a large window, a standing lamp, and a patterned carpet.

A hotel room with a bed, a desk, a sofa, a lamp, and a mirror.

2. Quality Inn & Suites Fort Madison near Hwy 61

Fort Madison

Lloyd

₩134,964

₩151,160 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with a bed, a sofa, a small table, a chair, a nightstand, and a painting on the wall.

A home gym with a treadmill, elliptical, and stationary bike, a large mirror, and a framed picture on the wall.

A modern kitchen with a dining area, featuring a central island, built-in appliances, and a large window with blinds.

A living room with a sofa, two armchairs, a coffee table with a plant, a lamp, and a TV on the wall.

3. Best Western Mt. Pleasant Inn

Mount Pleasant

Anthony

₩104,828

₩117,407 total

includes taxes & fees

Oct 8 - Oct 9

A spacious living room with a large sofa, two armchairs, a coffee table, and a fireplace.

A hotel room with a bed, a TV, a desk, and a chair.

A cozy living room with a grey sofa, two patterned armchairs, a wooden coffee table, and a brick accent wall.

A modern kitchen with a granite countertop, wooden chairs, and a large painting of a colorful horse.

4. AmericInn by Wyndham Mount Pleasant

Mount Pleasant

Valerie

₩113,224

₩126,811 total

includes taxes & fees

Oct 8 - Oct 9

An indoor swimming pool with a wooden ceiling, grey tiled floor, and several lounge chairs and tables around the pool area.

A spa area with a hot tub, wooden ceiling, and tiled walls.

A modern hotel lobby with blue and pink seating, a central coffee table, and a kitchen area in the background.

A multi-story hotel with a central entrance, a parking lot, and a clear sky.

5. Quality Inn & Suites Keokuk North

Keokuk

Susan

₩148,062

₩165,830 total

includes taxes & fees

Oct 4 - Oct 5

A row of single-family homes with a well-maintained lawn and a tree in the foreground.

A bedroom with a large bed, a bedside table with a lamp, a window with blinds, and a framed picture on the wall.

A modern kitchen with wooden cabinets, a white countertop, and a dining area with a white table and chairs.

A living room with a sofa, a patterned armchair, a dining table with chairs, a kitchen area with wooden cabinets and a refrigerator, and a television on a stand.

6. Nauvoo Vacation Villas & Condos

Nauvoo

Renae

₩193,752

₩205,337 total

includes taxes & fees

Sep 22 - Sep 23

A hotel room with two beds, a desk, a chair, and a large window.

A Super 8 motel with a brick facade, a covered entrance, and a parking lot with cars.

A bathroom with a bathtub, toilet, and sink.

A reception area with a white sofa, a potted plant, and a framed picture on the wall.

7. Super 8 by Wyndham Mt Pleasant

Mount Pleasant

frank

₩106,345

₩119,106 total

includes taxes & fees

Sep 13 - Sep 14

A large indoor swimming pool with a lifeguard chair, poolside chairs, and a view of the outside through large windows.

A reception desk with a "Welcome to the Hawk Eye State" sign, a digital kiosk, and a "Manager On Duty" sign.

A breakfast buffet area with a sign reading "EAT HERE" and various food items like cereal and pastries.

A modern hotel room with a large bed, two bedside tables with lamps, a small sofa, and a desk.

8. Hampton Inn Keokuk

Keokuk

Kristopher

₩147,914

₩165,664 total

includes taxes & fees

Sep 27 - Sep 28

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Top Southeast Iowa Hotel Reviews

Fun City Resort Hotel

10/10 Excellent

"Friendly staff"

Comfort Suites Burlington

8/10 Good

"Rooms were clean, the lady at desk when we checked in wasn't very friendly and didn't greet us or acknowledge us until she finished texting on her phone which was about 5 to 10min."

AmericInn by Wyndham West Burlington

8/10 Good

"We didn’t ask for maid service but 1 out of 5 days. When we did, she only picked up the trash and stuff on the bathroom floor and didn’t restock any of the towels or toilet paper. The staff was very helpful with getting extra wash cloths and hand towels."

Quality Inn & Suites Mount Pleasant

10/10 Excellent

"Gave me a welcome package with water, popcorn, cookies. Very nice and thoughtful."

Baymont by Wyndham Keokuk

8/10 Good

"Pool was closed"

Holiday Inn Express Hotel & Suites Burlington by IHG

10/10 Excellent

"Awesome"

Frequently asked questions

How much do business-friendly hotels in Southeast Iowa cost?

Expect to pay between ₩117,407 and ₩229,045 per night for business-friendly hotels in Southeast Iowa. Awesome deals on stays that are suitable for corporate travelers are a click away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

How many business-friendly hotels are there in Southeast Iowa?

Southeast Iowa has 17 business-friendly hotels to choose from. Whether you're attending a conference or working remotely, these properties are equipped with everything you need to be productive.

Why book your business-friendly hotel in Southeast Iowa with Expedia?

Expedia will help you find a fabulous business-friendly hotel when work takes you on the road. From free WiFi and parking to gyms and spas, our stays come with all you'll need to settle that big contract.

How can I find cheap business-friendly hotels in Southeast Iowa?

Expedia can help you easily find cheap business-friendly hotels in Southeast Iowa. Simply head to the "traveler experience" filter and click on "business friendly." This will show you properties with amenities designed to help you work comfortably and efficiently, like included breakfast and free WiFi. You can also choose your hotel star rating and budget to keep costs down.

What is there to do in Southeast Iowa near my business-friendly hotel?

You'll find tons of attractions to see during your time in Southeast Iowa. If you've planned a couple of nights in Nauvoo, Rheinberger House Museum is a must-see.

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Check availability on Southeast Iowa Business Hotels

Our top choices for Southeast Iowa business-friendly hotels

1. Cobblestone Inn & Suites - Fort Madison