Photo by Carl Anderson

Find hotels in Southwest Illinois, IL from ₩73,281

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 11 - Dec 12
Tomorrow
Dec 12 - Dec 13
This weekend
Dec 12 - Dec 14
Next weekend
Dec 19 - Dec 21

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Southwest Illinois hotels

Lobby lounge
Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
3.0 star property
Mount Vernon
9.6 out of 10, Exceptional, (1567)
"Great place to stay. Check in is easy and the hotel people are very nice."
United States
Duane
The price is ₩137,718
₩155,769 total
includes taxes & fees
Dec 25 - Dec 26
Drury Plaza Hotel Mt. Vernon
Terrace/patio
Home2 Suites by Hilton Carbondale

Home2 Suites by Hilton Carbondale

Home2 Suites by Hilton Carbondale
3.0 star property
Carbondale
8.8 out of 10, Excellent, (510)
"Great location. Nice, new hotel. Spacious room."
United States
Sabrina
The price is ₩140,663
₩161,735 total
includes taxes & fees
Dec 28 - Dec 29
Home2 Suites by Hilton Carbondale
Lobby
Comfort Suites Mount Vernon

Comfort Suites Mount Vernon

Comfort Suites Mount Vernon
2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1003)
"Rooms have been painted great breakfast close to interstate and restaurants"
United States
Stephen
The price is ₩164,986
₩186,027 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Comfort Suites Mount Vernon
Exterior
Holiday Inn Carbondale-Conference Center by IHG

Holiday Inn Carbondale-Conference Center by IHG

Holiday Inn Carbondale-Conference Center by IHG
3.0 star property
Carbondale
8.8 out of 10, Excellent, (640)
"Great staff!"
United States
Greg
The price is ₩156,781
₩180,269 total
includes taxes & fees
Dec 25 - Dec 26
Holiday Inn Carbondale-Conference Center by IHG
Lobby sitting area
Baymont by Wyndham Marion

Baymont by Wyndham Marion

Baymont by Wyndham Marion
2.5 star property
Marion
8.4 out of 10, Very Good, (1065)
"This place was nice for the money and our 1 night stay. "
United States
Charles
The price is ₩107,182
₩128,596 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Baymont by Wyndham Marion
Lobby
Drury Inn & Suites Marion

Drury Inn & Suites Marion

Drury Inn & Suites Marion
3.0 star property
Marion
9.4 out of 10, Exceptional, (1000)
"Hotel is very clean and staff is also friendly."
United States
Tonya
The price is ₩95,226
₩114,259 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Drury Inn & Suites Marion
Free buffet breakfast
Holiday Inn Express Hotel & Suites Sparta by IHG

Holiday Inn Express Hotel & Suites Sparta by IHG

Holiday Inn Express Hotel & Suites Sparta by IHG
2.5 star property
Sparta
9.2 out of 10, Wonderful, (368)
"Bed was comfortable, breakfast was a 10/10! "
United States
Junior
The price is ₩141,141
₩156,637 total
includes taxes & fees
Dec 26 - Dec 27
Holiday Inn Express Hotel & Suites Sparta by IHG
Exterior
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
2.5 star property
Murphysboro
9.4 out of 10, Exceptional, (511)
"great property, great breakfast, friendly and knowledgable staff."
United States
Ronald
The price is ₩162,642
₩180,500 total
includes taxes & fees
Dec 18 - Dec 19
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Indoor pool, sun loungers
DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon
4.0 star property
Mount Vernon
8.4 out of 10, Very Good, (765)
"Everything was great!"
United States
Rebecca
The price is ₩128,282
₩145,298 total
includes taxes & fees
Jan 10 - Jan 11, 2026
DoubleTree by Hilton Mt. Vernon
Lobby
SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
2.5 star property
Whittington
8.8 out of 10, Excellent, (903)
"Great place to stay."
United States
Stephen
The price is ₩105,849
₩117,471 total
includes taxes & fees
Dec 31 - Jan 1, 2026
SureStay Hotel by Best Western Whittington Rend Lake
Room, 1 King Bed, Accessible, Non Smoking | Down comforters, desk, laptop workspace, blackout drapes
Comfort Inn & Suites Carbondale University Area

Comfort Inn & Suites Carbondale University Area

Comfort Inn & Suites Carbondale University Area
2.5 star property
Carbondale
7.6 out of 10, Good, (516)
"Our room was clean and our stay was comfortable. We were not expecting a 5 star hotel due to the price and felt we received a good value for what we paid. We would stay again."
United States
James
The price is ₩109,972
₩126,446 total
includes taxes & fees
Dec 24 - Dec 25
Comfort Inn & Suites Carbondale University Area
Desk, iron/ironing board, free cribs/infant beds, rollaway beds
Super 8 by Wyndham Greenville

Super 8 by Wyndham Greenville

Super 8 by Wyndham Greenville
2.0 star property
Greenville
8.0 out of 10, Very Good, (757)
"A good breakfast, clean and tidy. I felt like I was at home."
United States
Olesia
The price is ₩97,438
₩108,137 total
includes taxes & fees
Dec 24 - Dec 25
Super 8 by Wyndham Greenville
Lobby
Comfort Inn & Suites Marion I-57

Comfort Inn & Suites Marion I-57

Comfort Inn & Suites Marion I-57
2.5 star property
Marion
9.4 out of 10, Exceptional, (1000)
"Very clean room, friendly staff, and the breakfast was tasty. Will stay there again"
United States
Marcus
The price is ₩158,246
₩189,863 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Comfort Inn & Suites Marion I-57
Room, 1 Queen Bed, Jetted Tub | Blackout drapes, free WiFi, bed sheets
Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach
2.5 star property
Granite City
7.8 out of 10, Good, (572)
"Room was clean, staff were really nice & helpful!! We will be back!"
United States
Shkaia
The price is ₩92,310
₩104,501 total
includes taxes & fees
Dec 13 - Dec 14
Red Lion Inn & Suites Pontoon Beach
In-room safe, desk, iron/ironing board, cribs/infant beds
Quality Inn & Suites Vandalia near I-70 and Hwy 51

Quality Inn & Suites Vandalia near I-70 and Hwy 51

Quality Inn & Suites Vandalia near I-70 and Hwy 51
2.5 star property
Vandalia
8.4 out of 10, Very Good, (1001)
"Awesome place to stay. Clean room, comfortable bed, amenities were accommodating, plenty of restaurants near by to choose from, and near the highway."
United States
Evelyn
The price is ₩99,681
₩108,620 total
includes taxes & fees
Dec 14 - Dec 15
Quality Inn & Suites Vandalia near I-70 and Hwy 51
Lobby sitting area
University Inn of Carbondale

University Inn of Carbondale

University Inn of Carbondale
2.5 star property
Carbondale
6.0 out of 10, (325)
"Yes everything was great"
United States
Jesse
University Inn of Carbondale
Breakfast, dinner and brunch served
The Principal Hotel

The Principal Hotel

The Principal Hotel
3.5 star property
Columbia
9.8 out of 10, Exceptional, (190)
"Great place. Very nice rooms, new and clean."
United States
Jeff
The price is ₩165,294
₩183,448 total
includes taxes & fees
Dec 14 - Dec 15
The Principal Hotel
Lobby
Comfort Inn & Suites Greenville I-70

Comfort Inn & Suites Greenville I-70

Comfort Inn & Suites Greenville I-70
2.5 star property
Greenville
8.4 out of 10, Very Good, (415)
"Room was clean and comfortable."
United States
Michael
The price is ₩132,824
₩147,408 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Comfort Inn & Suites Greenville I-70
Lobby
Quality Inn & Suites Marion

Quality Inn & Suites Marion

Quality Inn & Suites Marion
2.5 star property
Marion
7.4 out of 10, Good, (1001)
"Clean room. Friendly staff. My 2nd stay here. Good room for the price. Would stay here again. "
United States
Rodney
The price is ₩85,936
₩103,106 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Quality Inn & Suites Marion
Reception
Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites
2.5 star property
Centralia
9.6 out of 10, Exceptional, (598)
"Very beautiful place to stay "
United States
Valerie
The price is ₩176,708
₩197,877 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Best Western Plus Centralia Hotel & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Great weekend hotel deals in Southwest Illinois, IL

Showing deals for:Dec 19 - Dec 21

Image gallery for Red Bud Country Inn

Desk, laptop workspace, blackout drapes, iron/ironing board

Red Bud Country Inn

2.5 star property
Red Bud
9.0/10Wonderful (51 reviews)
10% off
Price is ₩131,212
₩291,238 total
includes taxes & fees
Red Bud Country Inn
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular Central United States attractions

Marion Cultural and Civic Center

3.9/5 (34 reviews)
Marion Cultural and Civic Center is just one of the places to see in Marion, so why not enjoy the other things to explore during your travels? While you're here, you can savor the top-notch restaurants.
See properties

O'Fallon Family Sports Park

4.2/5 (51 reviews)
Explore the great outdoors at O'Fallon Family Sports Park, a lovely green space in O'Fallon. Check out the shops and top-notch restaurants in this family-friendly area.
See properties

Learn more about Southwest Illinois

Explore a “natural city” of trees, enjoy incredible hilltop views, marvel at geological wonders and hop between small towns in this beautiful region.

See all hotels in Southwest Illinois
One of the northermost cypress swamps in the States, the Cache River State Natural area is home to Cypress trees that are over 1000 years old. This is shot from the hiking trail (no boat), and was just a sampling of the scores of cypress trees all around. #treetrove
Photo by Carl Anderson
Open Photo by Carl Anderson

Top Southwest Illinois Hotel Reviews

Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent
"Gteat facility. Wonderful staff, clean facility, great rooms, and an amazing evening 'snack'."
John 1-night trip
Posted 3 days ago
Drury Inn & Suites St. Louis O'Fallon, IL

More cheap stays in Southwest Illinois

Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon

1100 Eastgate Dr O'Fallon IL
The price is ₩63,734 per night from Dec 17 to Dec 18
₩63,734
₩73,281 total
Dec 17 - Dec 18
includes taxes & fees
7/10 Good! (1,001 reviews)

Hotels in Southwest Illinois with star-rating

Explore a world of travel with Expedia