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Find hotels in Southwest Illinois, IL from ₩69,102

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Compare 734 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Comfort Suites Mount Vernon

2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1008)
"Rooms have been painted great breakfast close to interstate and restaurants"
United States
Stephen
The price is ₩160,558
₩181,136 total
includes taxes & fees
Dec 8 - Dec 9
Comfort Suites Mount Vernon

Drury Plaza Hotel Mt. Vernon

3.0 star property
Mount Vernon
9.6 out of 10, Exceptional, (1562)
"Great place to stay. Check in is easy and the hotel people are very nice."
United States
Duane
The price is ₩138,448
₩156,596 total
includes taxes & fees
Dec 11 - Dec 12
Drury Plaza Hotel Mt. Vernon

Holiday Inn Express & Suites Mount Vernon by IHG

2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1005)
"Great stay"
United States
Cindy
The price is ₩139,936
₩158,246 total
includes taxes & fees
Dec 21 - Dec 22
Holiday Inn Express & Suites Mount Vernon by IHG

SureStay Hotel by Best Western Whittington Rend Lake

2.5 star property
Whittington
8.8 out of 10, Excellent, (903)
"Great place to stay."
United States
Stephen
The price is ₩106,410
₩118,093 total
includes taxes & fees
Dec 31 - Jan 1, 2026
SureStay Hotel by Best Western Whittington Rend Lake

Best Western Plus MidAmerica Hotel

2.5 star property
Mascoutah
9.0 out of 10, Wonderful, (1002)
"Hotel was clean and staff were very nice! Hotel is right off the interstate for very easy access to everything!"
United States
Crysta
The price is ₩161,368
₩183,927 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Best Western Plus MidAmerica Hotel

Comfort Inn & Suites Marion I-57

2.5 star property
Marion
9.4 out of 10, Exceptional, (1001)
"Very clean room, friendly staff, and the breakfast was tasty. Will stay there again"
United States
Marcus
The price is ₩159,085
₩190,870 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Comfort Inn & Suites Marion I-57

Quality Inn Mount Vernon, IL

2.5 star property
Mount Vernon
7.8 out of 10, Good, (534)
"It was nice and clean. It was a great place to just stop and sleep. The staff was very friendly, and it was located next to a lot of places to eat"
United States
Christopher
The price is ₩106,057
₩120,648 total
includes taxes & fees
Dec 14 - Dec 15
Quality Inn Mount Vernon, IL

Hampton Inn O'Fallon

2.5 star property
O'Fallon
9.2 out of 10, Wonderful, (809)
"The staff was courteous. Overall everything is good. We would return there again if we ever go back to the state. "
United States
Mark
The price is ₩143,736
₩166,705 total
includes taxes & fees
Dec 26 - Dec 27
Hampton Inn O'Fallon

Quality Inn & Suites Vandalia near I-70 and Hwy 51

2.5 star property
Vandalia
8.4 out of 10, Very Good, (1003)
"Awesome place to stay. Clean room, comfortable bed, amenities were accommodating, plenty of restaurants near by to choose from, and near the highway."
United States
Evelyn
The price is ₩91,032
₩99,207 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Quality Inn & Suites Vandalia near I-70 and Hwy 51

Super 8 by Wyndham Mt. Vernon IL

2.5 star property
Mount Vernon
7.8 out of 10, Good, (1002)
"Clean comfortable room and bed. Great location to many restaurants and shopping. "
United States
Patricia
The price is ₩91,474
₩104,464 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Super 8 by Wyndham Mt. Vernon IL

Baymont by Wyndham Marion

2.5 star property
Marion
8.4 out of 10, Very Good, (1065)
"This place was nice for the money and our 1 night stay. "
United States
Charles
The price is ₩113,348
₩135,995 total
includes taxes & fees
Dec 15 - Dec 16
Baymont by Wyndham Marion

Drury Inn & Suites St. Louis O'Fallon, IL

3.0 star property
O'Fallon
9.6 out of 10, Exceptional, (1005)
"Excellent location, clean and spacious room, great morning breakfast with numerous choices and of course helpful and pleasant staff."
United States
David
The price is ₩150,232
₩174,242 total
includes taxes & fees
Dec 14 - Dec 15
Drury Inn & Suites St. Louis O'Fallon, IL

Holiday Inn Express Hotel & Suites Marion Northeast by IHG

2.5 star property
Marion
9.0 out of 10, Wonderful, (924)
"yes the room was great and the staff was great! "
United States
Amador
The price is ₩142,882
₩171,429 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Holiday Inn Express Hotel & Suites Marion Northeast by IHG

Ramada by Wyndham Vandalia

2.0 star property
Vandalia
7.8 out of 10, Good, (807)
"Staffing was awesome and helpful. "
United States
Warren
The price is ₩100,165
₩109,159 total
includes taxes & fees
Dec 9 - Dec 10
Ramada by Wyndham Vandalia

Best Western Plus Centralia Hotel & Suites

2.5 star property
Centralia
9.6 out of 10, Exceptional, (598)
"Very beautiful place to stay "
United States
Valerie
The price is ₩177,645
₩198,927 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Best Western Plus Centralia Hotel & Suites

Drury Inn & Suites Marion

3.0 star property
Marion
9.4 out of 10, Exceptional, (1000)
"Great hotel and very clean "
United States
Jose
The price is ₩95,731
₩114,865 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Drury Inn & Suites Marion

Super 8 by Wyndham Greenville

2.0 star property
Greenville
8.0 out of 10, Very Good, (757)
"A good breakfast, clean and tidy. I felt like I was at home."
United States
Olesia
The price is ₩97,955
₩108,710 total
includes taxes & fees
Dec 14 - Dec 15
Super 8 by Wyndham Greenville

Comfort Inn & Suites Greenville I-70

2.5 star property
Greenville
8.4 out of 10, Very Good, (414)
"Room was clean and comfortable."
United States
Michael
The price is ₩131,466
₩145,901 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Comfort Inn & Suites Greenville I-70

Best Western Marion Hotel

2.5 star property
Marion
8.2 out of 10, Very Good, (1000)
"Friendly staff"
United States
Brent
The price is ₩96,276
₩115,512 total
includes taxes & fees
Dec 15 - Dec 16
Best Western Marion Hotel

Laketree Inn And Suites Marion

2.0 star property
Marion
8.0 out of 10, Very Good, (177)
"Neat little Mom and Pop hotel on the edge of Shawnee National Forest. Very few perks, no breakfast or pool, but solid internet and there's a great BBQ place right down the road. We will be back."
United States
Sarah
The price is ₩103,096
₩114,416 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Laketree Inn And Suites Marion
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Stay near popular Central United States attractions

Learn more about Southwest Illinois

Explore a “natural city” of trees, enjoy incredible hilltop views, marvel at geological wonders and hop between small towns in this beautiful region.

One of the northermost cypress swamps in the States, the Cache River State Natural area is home to Cypress trees that are over 1000 years old. This is shot from the hiking trail (no boat), and was just a sampling of the scores of cypress trees all around. #treetrove
Photo by Carl Anderson
Open Photo by Carl Anderson

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