Find Luxury Hotels in Southwest Illinois, IL

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Southwest Illinois Luxury Hotels

Next weekend
In two weeks

Our top choices for Southwest Illinois luxury hotels

DoubleTree by Hilton Collinsville - St. Louis

DoubleTree by Hilton Collinsville - St. Louis
4.0 star property
Eastport
8.2 out of 10, Very Good, (1,000 reviews)
  • cleanliness
    Upscale St. Louis hotel offers steakhouse, indoor pool, and 24-hour fitness center.
The price is ₩198,224
₩227,919 total
includes taxes & fees
May 4 - May 5
DoubleTree by Hilton Collinsville - St. Louis

Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
4.5 star property
Carterville
9.4 out of 10, Exceptional, (423 reviews)
  • cleanliness
    Indulge in a luxurious retreat featuring a full-service spa, indoor pool, and casino gaming in the heart of Carterville.
The price is ₩196,271
₩217,824 total
includes taxes & fees
Apr 26 - Apr 27
Walker's Bluff Casino Resort

DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon
4.0 star property
Mount Vernon
8.4 out of 10, Very Good, (795 reviews)
  • cleanliness
    Plush beds and serene pool define luxury at Mt. Vernon retreat where spa awaits after exploration.
The price is ₩193,145
₩217,373 total
includes taxes & fees
Apr 24 - Apr 25
DoubleTree by Hilton Mt. Vernon

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very Good, (1,004 reviews)
  • cleanliness
    Indulge in lavish comfort at this St. Charles retreat featuring a full-service spa, seasonal pool, and 6 exceptional restaurants.
The price is ₩240,449
₩306,074 total
includes taxes & fees
Apr 26 - Apr 27
Ameristar Casino Resort and Spa

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (3,993 reviews)
The price is ₩229,876
₩271,091 total
includes taxes & fees
May 3 - May 4
Hyatt Regency St. Louis at The Arch

Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,134 reviews)
The price is ₩240,225
₩285,698 total
includes taxes & fees
Apr 19 - Apr 20
Live by Loews - St.Louis

Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
4.0 star property
Downtown St. Louis
7.6 out of 10, Good, (1,092 reviews)
The price is ₩273,962
₩325,820 total
includes taxes & fees
May 3 - May 4
Hilton St. Louis at the Ballpark

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,000 reviews)
  • cleanliness
    Lavish riverside luxury awaits at the Four Seasons St. Louis with spa indulgences and poolside bliss.
The price is ₩709,869
₩830,043 total
includes taxes & fees
Apr 6 - Apr 7
Four Seasons Hotel St Louis

21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1,717 reviews)
  • cleanliness
    Indulge in artistic luxury at this downtown St. Louis hotel with spa services and indoor pool.
The price is ₩225,117
₩270,780 total
includes taxes & fees
Apr 5 - Apr 6
21C Museum Hotel St Louis

St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West
8.6 out of 10, Excellent, (1,000 reviews)
  • cleanliness
    Experience grandeur in a historic hotel with 7 restaurants, seasonal pool, and concierge services in downtown St. Louis.
The price is ₩326,646
₩388,470 total
includes taxes & fees
Apr 19 - Apr 20
St. Louis Union Station Hotel, Curio Collection by Hilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Southwest Illinois Hotel Reviews