A large white building with a dome and a statue in front, surrounded by fountains and trees.

Find Luxury Hotels in St. Louis, MO

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check availability on St. Louis Luxury Hotels

Tonight
Oct 11 - Oct 12
Tomorrow
Oct 12 - Oct 13
Next weekend
Oct 16 - Oct 18
In two weeks
Oct 23 - Oct 25

Our top choices for St. Louis luxury hotels

1. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Lavish riverside luxury awaits at the Four Seasons St. Louis with spa indulgences and poolside bliss.
₩502,598
₩587,683 total
includes taxes & fees
Oct 12 - Oct 13
Four Seasons Hotel St Louis

2. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Ritz-Carlton elegance defines this St. Louis retreat with indulgent spa services and dining excellence.
₩776,011
₩905,896 total
includes taxes & fees
Nov 1 - Nov 2
The Ritz-Carlton, St. Louis

3. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Indulge in lavish comfort at this St. Charles retreat featuring a full-service spa, seasonal pool, and 6 exceptional restaurants.
₩240,041
₩302,787 total
includes taxes & fees
Oct 12 - Oct 13
Ameristar Casino Resort and Spa

4. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
Central West End
  • Indulge in historic elegance at this St. Louis gem featuring 3 restaurants, a spectacular pool area, and luxurious rooms near Forest Park.
₩215,782
₩293,981 total
includes taxes & fees
Nov 1 - Nov 2
The Royal Sonesta Chase Park Plaza St. Louis

5. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Indulge in artistic luxury at this downtown St. Louis hotel with spa services and indoor pool.
₩192,528
₩231,822 total
includes taxes & fees
Nov 1 - Nov 2
21C Museum Hotel St Louis

6. Hyatt Centric Downtown St. Louis

Hyatt Centric Downtown St. Louis
Downtown West
₩215,782
₩254,469 total
includes taxes & fees
Oct 18 - Oct 19
Hyatt Centric Downtown St. Louis

7. The Cheshire

The Cheshire
Richmond Heights
₩198,908
₩236,180 total
includes taxes & fees
Oct 18 - Oct 19
The Cheshire

8. The Westin St. Louis

The Westin St. Louis
Downtown St. Louis
  • Opulent downtown retreat with pillowtop beds, soaking tubs, and Italian dining moments from Busch Stadium.
₩175,748
₩205,500 total
includes taxes & fees
Oct 18 - Oct 19
The Westin St. Louis

9. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
Brentwood
₩175,561
₩208,480 total
includes taxes & fees
Nov 1 - Nov 2
Drury Plaza Hotel St. Louis Brentwood

10. DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield
Chesterfield
  • Chesterfield hotel offers plush comforts with indoor tennis courts, dual pools, and premium bedding.
₩185,733
₩215,429 total
includes taxes & fees
Oct 30 - Oct 31
DoubleTree by Hilton Hotel St. Louis - Chesterfield
View all properties

Top St. Louis Hotel Reviews

Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent
"The staff was very helpful and nice. The food was very good as well."
Thomas 3-night trip
Posted 1 hour ago
Drury Plaza Hotel St. Louis Union Station
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent
"We loved our stay at Drury Plaza- no complaints!!"
Cathleen 1-night trip
Posted 1 hour ago
Drury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

10/10 Excellent
"Every thing was good"
michael 1-night trip
Posted 1 hour ago
Pear Tree Inn St. Louis Airport
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

8/10 Good
"friendly staff, great for kids"
Samantha 2-night trip
Posted 3 hours ago
Pear Tree Inn St. Louis Near Union Station
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

10/10 Excellent
"Good breakfast, nice service, nice room! Really good shower too, let you set the temperature"
Sarah 2-night trip
Posted 4 hours ago
Clayton Plaza Hotel & Extended Stay
Moonrise Hotel

Moonrise Hotel

10/10 Excellent
"Such a cute place to stay, and convenient to a music venue and restaurants."
Jessie 1-night trip
Posted 5 hours ago
Moonrise Hotel
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

8/10 Good
"Wonderful stay for a small bachelorette party. Had a wonderful time!"
Kara 1-night trip
Posted 1 day ago
Ameristar Casino Resort and Spa

Frequently asked questions

Are you searching for a great accommodation for your luxury getaway to St. Louis?
Travel to St. Louis Lambert Intl. Airport (STL) Airport or Belleville, IL (BLV-MidAmerica-St. Louis) Airport, and then treat yourself to a stay at one of 8 St. Louis luxury hotels. Known for its art and theater, St. Louis also has some interesting things to see and do including St. Louis Union Station and St. Louis Zoo, so you may want to take in the local sights during your visit.
What's the best high-end place to stay in St. Louis?
21C Museum Hotel St Louis is a luxury hotel with spa services and valet parking, and it's a popular choice for Expedia travelers looking for an elegant place to stay. St. Louis Union Station Hotel, Curio Collection by Hilton and Ameristar Casino Resort and Spa are other upscale choices for your trip.
How many luxury hotels should I expect to find in St. Louis?
Lie in the lap of luxury during your getaway to St. Louis in one of Expedia's 8 luxury hotels.
When can I expect good weather in St. Louis?
Planning for the weather is a good way to make your trip to St. Louis relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for St. Louis is 54 inches.
What's there to see and do in St. Louis?
Take in some sights and attractions while you're in St. Louis by visiting St. Louis Union Station, St. Louis Zoo, and St. Louis Aquarium at Union Station. If you have extra time while you're in the area, you might want to see The St. Louis Wheel and Energizer Park.
How can I get around St. Louis?
It's easier to get around town comfortably when you know your options. Take advantage of metro transit at Stadium Station, 8th and Pine Station, and Convention Center Station.

Explore a world of travel with Expedia