The Best Luxury Hotels in St. Louis, MO from ₩171,060 in 2026

A large white building with a dome and a statue in front, surrounded by fountains and trees.

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Our top choices for St. Louis luxury hotels

A modern hotel lobby with a glass facade, seating area, and a staircase.

A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.

A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.

A couple relaxing by a window overlooking a bridge and water.

1. Four Seasons Hotel St Louis

Downtown St. Louis

Lavish riverside luxury awaits at the Four Seasons St. Louis with spa indulgences and poolside bliss.

₩502,628

₩587,717 total

includes taxes & fees

Oct 6 - Oct 7

A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

A bar area with a marble counter, bar stools, and a variety of liquor bottles.

An outdoor patio with a brick fireplace, wicker furniture, and a dining table set with food and drinks.

A grand lobby with a central seating area, a staircase, and a decorative ceiling.

2. The Royal Sonesta Chase Park Plaza St. Louis

Central West End

Indulge in historic elegance at this St. Louis gem featuring 3 restaurants, a spectacular pool area, and luxurious rooms near Forest Park.

₩215,795

₩293,997 total

includes taxes & fees

Nov 1 - Nov 2

An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.

A bakery display case with various pastries and cakes.

A bar area with multiple seating arrangements, a stage, and a chandelier.

A grand lobby with a central chandelier, multiple levels, and rows of liquor bottles.

3. Ameristar Casino Resort and Spa

St. Charles

Indulge in lavish comfort at this St. Charles retreat featuring a full-service spa, seasonal pool, and 6 exceptional restaurants.

₩226,719

₩287,213 total

includes taxes & fees

Oct 12 - Oct 13

A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.

A reception desk with a wooden finish and the name "IDOL WOLF" on it.

A spacious lobby with multiple seating areas, a pool table, and artwork on the walls.

A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.

4. 21C Museum Hotel St Louis

Downtown West

Indulge in artistic luxury at this downtown St. Louis hotel with spa services and indoor pool.

₩192,540

₩231,837 total

includes taxes & fees

Oct 25 - Oct 26

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

A lobby with a reception desk, seating area with sofas and ottomans, and a patterned rug.

An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.

A spa bath with a sign indicating a capacity of 8 persons.

5. Drury Plaza Hotel St. Louis Brentwood

Brentwood

₩178,252

₩211,655 total

includes taxes & fees

Nov 1 - Nov 2

A large sports complex with multiple fields, a swimming pool, and a covered pavilion.

A hotel room with orange furniture, a glass coffee table, a dining area with a table and chairs, and a patterned carpet.

A large, multi-story hotel with the name "Doubletree by Hilton" prominently displayed on the facade.

A spacious lobby with a brown leather sofa, multiple chairs, a coffee table with a skull decoration, and a large chandelier.

6. DoubleTree by Hilton Hotel St. Louis - Chesterfield

Chesterfield

Chesterfield hotel offers plush comforts with indoor tennis courts, dual pools, and premium bedding.

₩185,744

₩215,441 total

includes taxes & fees

Oct 30 - Oct 31

A bar area with wooden tables, leather seating, and a bar counter.

A bar area with a wooden counter, hanging glasses, and a liquor display.

A covered outdoor area with two tables and two chairs, a white railing, and a view of a road and trees.

A hotel room with a bed, bedside table, lamp, chair, desk, microwave, refrigerator, and a door.

7. The Inn at Elijah McLeans

Washington

₩180,946

₩206,007 total

includes taxes & fees

Oct 6 - Oct 7

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Top St. Louis Hotel Reviews

Moonrise Hotel

8/10 Good

"The sheets were stained and dirty, the bed was not well made. The staff at reception, especially Nina, are amazing and extremely helpful!! I wish the hotel were tidier and lobby furniture freshened up some, the location is ideal!"

Pear Tree Inn St. Louis Airport

10/10 Excellent

"We had a pleasant stay here. Lots to do nearby. Would recommend."

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent

"The room was very clean and well-maintained. Staff was friendly and the amenities were very generous. Beautiful historical hotel. Close to the Aquarium and various restaurants."

Hyatt Regency St. Louis at The Arch

8/10 Good

"Exceptional location and you can literally walk outside to the archway. Super clean, nice staff, clean rooms. I was there for work where I could have gone to others for cheaper but not likely the view and location. Only downside was the garage system was not working all weekend, so self parking was a bit problematic, but I know that stuff happens. I would love to stay there if I come back in town."

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent

"The staff was very helpful and friendly especially the breakfast staff, Lavern would greet each person with a smile. She is so sweet. It is a beautiful historic hotel."

Frequently asked questions

Are you searching for a great accommodation for your luxury getaway to St. Louis?

Travel to St. Louis Lambert Intl. Airport (STL) Airport or Belleville, IL (BLV-MidAmerica-St. Louis) Airport, and then treat yourself to a stay at one of 8 St. Louis luxury hotels. Known for its art and theater, St. Louis also has some interesting things to see and do including St. Louis Union Station and St. Louis Zoo, so you may want to take in the local sights during your visit.

What's the best high-end place to stay in St. Louis?

21C Museum Hotel St Louis is a luxury hotel with spa services and valet parking, and it's a popular choice for Expedia travelers looking for an elegant place to stay. St. Louis Union Station Hotel, Curio Collection by Hilton and Ameristar Casino Resort and Spa are other upscale choices for your trip.

How many luxury hotels should I expect to find in St. Louis?

Lie in the lap of luxury during your getaway to St. Louis in one of Expedia's 8 luxury hotels.

When can I expect good weather in St. Louis?

Planning for the weather is a good way to make your trip to St. Louis relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for St. Louis is 54 inches.

What's there to see and do in St. Louis?

Take in some sights and attractions while you're in St. Louis by visiting St. Louis Union Station, St. Louis Zoo, and St. Louis Aquarium at Union Station. If you have extra time while you're in the area, you might want to see The St. Louis Wheel and Energizer Park.

How can I get around St. Louis?

It's easier to get around town comfortably when you know your options. Take advantage of metro transit at Stadium Station, 8th and Pine Station, and Convention Center Station.

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Book Luxury Hotels in St. Louis on Expedia.com

Find Luxury Hotels in St. Louis, MO

Change your mind

Treat yourself

Be picky

Check availability on St. Louis Luxury Hotels

Our top choices for St. Louis luxury hotels

1. Four Seasons Hotel St Louis

2. The Royal Sonesta Chase Park Plaza St. Louis

3. Ameristar Casino Resort and Spa

4. 21C Museum Hotel St Louis

5. Drury Plaza Hotel St. Louis Brentwood

6. DoubleTree by Hilton Hotel St. Louis - Chesterfield

7. The Inn at Elijah McLeans

Top St. Louis Hotel Reviews

Moonrise Hotel

Pear Tree Inn St. Louis Airport

Drury Plaza Hotel St. Louis Union Station

Hyatt Regency St. Louis at The Arch

Drury Plaza Hotel St. Louis at the Arch

Frequently asked questions

Explore a world of travel with Expedia