A large white building with a dome and a statue in front, surrounded by fountains and trees.

Find Luxury Hotels in St. Louis, MO

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on St. Louis Luxury Hotels

Tonight
Oct 18 - Oct 19
Tomorrow
Oct 19 - Oct 20
Next weekend
Oct 23 - Oct 25
In two weeks
Oct 30 - Nov 1

Our top choices for St. Louis luxury hotels

A modern hotel lobby with a glass facade, seating area, and a staircase.
A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.
A couple relaxing by a window overlooking a bridge and water.
A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.

1. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Lavish riverside luxury awaits at the Four Seasons St. Louis with spa indulgences and poolside bliss.
₩500,344
₩585,042 total
includes taxes & fees
Oct 25 - Oct 26
Four Seasons Hotel St Louis
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A bakery display case with various pastries and cakes.
A bar area with multiple seating arrangements, a stage, and a chandelier.
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.

2. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Indulge in lavish comfort at this St. Charles retreat featuring a full-service spa, seasonal pool, and 6 exceptional restaurants.
₩212,412
₩270,381 total
includes taxes & fees
Nov 16 - Nov 17
Ameristar Casino Resort and Spa
A spacious lobby with a grand chandelier, a reception desk, and a large wall mural.
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.
A grand lobby with a central seating area, a staircase, and a decorative ceiling.
An outdoor patio with a brick fireplace, wicker furniture, and a dining table set with food and drinks.

3. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
Central West End
  • Indulge in historic elegance at this St. Louis gem featuring 3 restaurants, a spectacular pool area, and luxurious rooms near Forest Park.
₩214,814
₩292,663 total
includes taxes & fees
Nov 15 - Nov 16
The Royal Sonesta Chase Park Plaza St. Louis
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A spacious lobby with multiple seating areas, a pool table, and artwork on the walls.
A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."

4. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Indulge in artistic luxury at this downtown St. Louis hotel with spa services and indoor pool.
₩191,665
₩230,783 total
includes taxes & fees
Nov 15 - Nov 16
21C Museum Hotel St Louis
A bartender pouring a drink into a martini glass.
Two people sitting by a window with a cityscape view.
Three people in white robes sitting on a bed with a wooden headboard, holding glasses of champagne.
A person sitting by a pool with a striped towel and sunglasses on a book.

5. Hyatt Centric Downtown St. Louis

Hyatt Centric Downtown St. Louis
Downtown West
₩214,814
₩253,328 total
includes taxes & fees
Oct 25 - Oct 26
Hyatt Centric Downtown St. Louis
A modern hotel room with a large bed, a nightstand, a mirror, and a view of the city through arched windows.
A modern living room with a grey sofa, a round wooden coffee table, and a large window with a city view.
A lobby with wooden paneling, a green wall, and two armchairs.
A modern restaurant interior with high tables, chairs, and a central bar area.

6. The Westin St. Louis

The Westin St. Louis
Downtown St. Louis
  • Opulent downtown retreat with pillowtop beds, soaking tubs, and Italian dining moments from Busch Stadium.
₩174,960
₩204,579 total
includes taxes & fees
Nov 15 - Nov 16
The Westin St. Louis
A spacious lobby with a brown leather sofa, multiple chairs, a coffee table with a skull decoration, and a large chandelier.
A hotel room with a large bed, a desk with a chair, a television, a mirror, and a wardrobe.
An indoor tennis court with multiple courts, a net, and players.
A large, multi-story hotel with the name "Doubletree by Hilton" prominently displayed on the facade.

7. DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield
Chesterfield
  • Chesterfield hotel offers plush comforts with indoor tennis courts, dual pools, and premium bedding.
₩184,900
₩214,462 total
includes taxes & fees
Oct 30 - Oct 31
DoubleTree by Hilton Hotel St. Louis - Chesterfield
A restaurant with round tables and chairs, a bar area, and a patterned ceiling.
A lobby with a reception desk, seating area with sofas and ottomans, and a patterned rug.
A Drury Plaza Hotel with a large parking lot and multiple cars parked in front.
A spa bath with a sign indicating a capacity of 8 persons.

8. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
Brentwood
₩170,771
₩202,822 total
includes taxes & fees
Nov 1 - Nov 2
Drury Plaza Hotel St. Louis Brentwood
A bar area with wooden tables, leather seating, and a bar counter.
A hotel room with a bed, bedside table, lamp, chair, desk, microwave, refrigerator, and a door.
A large white building with a central tower, a parking lot, and a tree with red leaves.
A covered outdoor area with two tables and two chairs, a white railing, and a view of a road and trees.

9. The Inn at Elijah McLeans

The Inn at Elijah McLeans
Washington
₩180,124
₩205,070 total
includes taxes & fees
Oct 19 - Oct 20
The Inn at Elijah McLeans
View all properties

Top St. Louis Hotel Reviews

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

8/10 Good
"Great experience"
Tyronesia 2-night trip
Posted less than an hour ago
Pear Tree Inn St. Louis Near Union Station
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent
"We rode the train an the hotel is just and 8 min walk from the metro. The hotel was very accommodating and allowed us to check in early. Staff was very friendly.riims were clean and had a great view."
Krystal 2-night trip
Posted 3 hours ago
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent
"Great location and amazing staff. Also afternoon snacks and drinks are great additions."
Mark 2-night trip
Posted 5 hours ago
Drury Plaza Hotel St. Louis at the Arch
Moonrise Hotel

Moonrise Hotel

10/10 Excellent
"Had the Vincent Price suite with a city view. Also loved the rooftop terrace."
Mark 1-night trip
Posted 22 hours ago
Moonrise Hotel
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

10/10 Excellent
"Easy check in"
Mark 1-night trip
Posted 1 day ago
Renaissance St. Louis Airport Hotel

Frequently asked questions

Are you searching for a great accommodation for your luxury getaway to St. Louis?
Travel to St. Louis Lambert Intl. Airport (STL) Airport or Belleville, IL (BLV-MidAmerica-St. Louis) Airport, and then treat yourself to a stay at one of 8 St. Louis luxury hotels. Known for its art and theater, St. Louis also has some interesting things to see and do including St. Louis Union Station and St. Louis Zoo, so you may want to take in the local sights during your visit.
What's the best high-end place to stay in St. Louis?
21C Museum Hotel St Louis is a luxury hotel with spa services and valet parking, and it's a popular choice for Expedia travelers looking for an elegant place to stay. St. Louis Union Station Hotel, Curio Collection by Hilton and Ameristar Casino Resort and Spa are other upscale choices for your trip.
How many luxury hotels should I expect to find in St. Louis?
Lie in the lap of luxury during your getaway to St. Louis in one of Expedia's 8 luxury hotels.
When can I expect good weather in St. Louis?
Planning for the weather is a good way to make your trip to St. Louis relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for St. Louis is 54 inches.
What's there to see and do in St. Louis?
Take in some sights and attractions while you're in St. Louis by visiting St. Louis Union Station, St. Louis Zoo, and St. Louis Aquarium at Union Station. If you have extra time while you're in the area, you might want to see The St. Louis Wheel and Energizer Park.
How can I get around St. Louis?
It's easier to get around town comfortably when you know your options. Take advantage of metro transit at Stadium Station, 8th and Pine Station, and Convention Center Station.

Explore a world of travel with Expedia