A large white building with a dome and a statue in front, surrounded by fountains and trees.

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Check availability on St. Louis Luxury Hotels

Tonight
Oct 5 - Oct 6
Tomorrow
Oct 6 - Oct 7
This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Our top choices for St. Louis luxury hotels

A modern hotel lobby with a glass facade, seating area, and a staircase.
A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.
A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.
A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.

1. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Lavish riverside luxury awaits at the Four Seasons St. Louis with spa indulgences and poolside bliss.
₩502,628
₩587,717 total
includes taxes & fees
Oct 6 - Oct 7
Four Seasons Hotel St Louis
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.
A restaurant with multiple dining tables and chairs, a bar area with shelves of bottles, and a large mirror above the bar.
An outdoor patio with a brick fireplace, wicker furniture, and a dining table set with food and drinks.
A bar area with a marble counter, bar stools, and a variety of liquor bottles.

2. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
Central West End
  • Indulge in historic elegance at this St. Louis gem featuring 3 restaurants, a spectacular pool area, and luxurious rooms near Forest Park.
₩215,795
₩293,997 total
includes taxes & fees
Nov 1 - Nov 2
The Royal Sonesta Chase Park Plaza St. Louis
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A bakery display case with various pastries and cakes.
A bar area with multiple seating arrangements, a stage, and a chandelier.
A grand lobby with a central chandelier, multiple levels, and rows of liquor bottles.

3. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Indulge in lavish comfort at this St. Charles retreat featuring a full-service spa, seasonal pool, and 6 exceptional restaurants.
₩226,719
₩287,213 total
includes taxes & fees
Oct 12 - Oct 13
Ameristar Casino Resort and Spa
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."
A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.
A reception desk with a wooden finish and the name "IDOL WOLF" on it.

4. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Indulge in artistic luxury at this downtown St. Louis hotel with spa services and indoor pool.
₩192,540
₩231,837 total
includes taxes & fees
Nov 1 - Nov 2
21C Museum Hotel St Louis
A restaurant with round tables and chairs, a bar area, and a patterned ceiling.
A spa bath with a sign indicating a capacity of 8 persons.
An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.
A Drury Plaza Hotel with a large parking lot and multiple cars parked in front.

5. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
Brentwood
₩178,252
₩211,655 total
includes taxes & fees
Nov 1 - Nov 2
Drury Plaza Hotel St. Louis Brentwood
A spacious lobby with a brown leather sofa, multiple chairs, a coffee table with a skull decoration, and a large chandelier.
A hotel room with orange furniture, a glass coffee table, a dining area with a table and chairs, and a patterned carpet.
A large, multi-story hotel with the name "Doubletree by Hilton" prominently displayed on the facade.
An indoor tennis court with multiple courts, a net, and players.

6. DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield
Chesterfield
  • Chesterfield hotel offers plush comforts with indoor tennis courts, dual pools, and premium bedding.
₩185,744
₩215,441 total
includes taxes & fees
Oct 30 - Oct 31
DoubleTree by Hilton Hotel St. Louis - Chesterfield
A bar area with wooden tables, leather seating, and a bar counter.
A bar area with a wooden counter, hanging glasses, and a liquor display.
A covered outdoor area with two tables and two chairs, a white railing, and a view of a road and trees.
A large white building with a central tower, a parking lot, and a tree with red leaves.

7. The Inn at Elijah McLeans

The Inn at Elijah McLeans
Washington
₩180,946
₩206,007 total
includes taxes & fees
Oct 6 - Oct 7
The Inn at Elijah McLeans
View all properties

Top St. Louis Hotel Reviews

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

10/10 Excellent
"The staff was very professional and supportive; even though I checked in at 2 a.m. It felt like a good place to land after a brutal day full of 9 hour layovers and flying across country. I love the convenient closeness to the airport too."
Sharon 1-night trip
Posted less than an hour ago
Pear Tree Inn St. Louis Airport
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

8/10 Good
"Older hotel but good stay. Not 5 star hotel but good for affordability. Great location. Staff were friendly and hospitable. Great complimentary breakfast. Free parking Friday and Saturday."
Lana 1-night trip
Posted 1 hour ago
Clayton Plaza Hotel & Extended Stay
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

10/10 Excellent
"Great stay and rooms were very clean,amenities provided was a plus"
Ronnie 1-night trip
Posted 2 hours ago
Hollywood Casino & Hotel St. Louis
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent
"q"
Jeffrey 2-night trip
Posted 4 hours ago
Pear Tree Inn St. Louis Near Union Station
Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

8/10 Good
"Clean hotel"
Lisa 1-night trip
Posted 5 hours ago
Drury Plaza Hotel St. Louis Union Station
Moonrise Hotel

Moonrise Hotel

8/10 Good
"The sheets were stained and dirty, the bed was not well made. The staff at reception, especially Nina, are amazing and extremely helpful!! I wish the hotel were tidier and lobby furniture freshened up some, the location is ideal!"
Thomas 1-night trip
Posted 14 hours ago
Moonrise Hotel

Frequently asked questions

Are you searching for a great accommodation for your luxury getaway to St. Louis?
Travel to St. Louis Lambert Intl. Airport (STL) Airport or Belleville, IL (BLV-MidAmerica-St. Louis) Airport, and then treat yourself to a stay at one of 8 St. Louis luxury hotels. Known for its art and theater, St. Louis also has some interesting things to see and do including St. Louis Union Station and St. Louis Zoo, so you may want to take in the local sights during your visit.
What's the best high-end place to stay in St. Louis?
21C Museum Hotel St Louis is a luxury hotel with spa services and valet parking, and it's a popular choice for Expedia travelers looking for an elegant place to stay. St. Louis Union Station Hotel, Curio Collection by Hilton and Ameristar Casino Resort and Spa are other upscale choices for your trip.
How many luxury hotels should I expect to find in St. Louis?
Lie in the lap of luxury during your getaway to St. Louis in one of Expedia's 8 luxury hotels.
When can I expect good weather in St. Louis?
Planning for the weather is a good way to make your trip to St. Louis relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for St. Louis is 54 inches.
What's there to see and do in St. Louis?
Take in some sights and attractions while you're in St. Louis by visiting St. Louis Union Station, St. Louis Zoo, and St. Louis Aquarium at Union Station. If you have extra time while you're in the area, you might want to see The St. Louis Wheel and Energizer Park.
How can I get around St. Louis?
It's easier to get around town comfortably when you know your options. Take advantage of metro transit at Stadium Station, 8th and Pine Station, and Convention Center Station.

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