The Best Hotels Closest to Biomuseo in Panama City for 2026

A modern building with colorful geometric shapes and a clear blue sky.

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Our top choices for Biomuseo hotels

A spacious indoor courtyard with tiled flooring, multiple seating areas, and hanging plants.

A room with a large window, a television mounted on the wall, and two chairs.

A living room with a sofa, a coffee table with books, a chandelier, and a kitchen with wooden cabinets and granite countertops.

An open door revealing a balcony with a wrought iron railing, potted plants, and a window with a curtain.

1. La Isabela Suites

San Felipe, 2.5 km from Biomuseo

David

₩209,641

₩230,605 total

includes taxes & fees

Oct 25 - Oct 26

A restaurant with multiple dining tables, chairs, and a central water feature.

A bar area with multiple seating options, a bar counter, and a fireplace.

A rooftop terrace with tables and chairs, a view of two white towers, and a building with a large window.

A historic building with ornate stonework and a balcony with plants.

2. Hotel La Compañía Casco Antiguo

San Felipe, 2.4 km from Biomuseo

Carlos A

₩372,228

₩409,451 total

includes taxes & fees

Oct 23 - Oct 24

A balcony with a table, chairs, and a view of a city skyline across a body of water.

A spacious lobby with a round coffee table, seating areas, and a large wall clock.

A spacious living room with a high ceiling, large windows, and a decorative ceiling fan.

A spacious lobby with high ceilings, modern furniture, and decorative lighting fixtures.

3. Sofitel Legend Casco Viejo, Panama City

San Felipe, 2.5 km from Biomuseo

Jose

₩467,199

₩513,919 total

includes taxes & fees

Nov 3 - Nov 4

A hotel room with two beds, a ceiling fan, a large mirror, and a view of the outdoors.

A multi-story building with ornate balconies, large windows, and decorative moldings.

A hotel room with a large bed, a ceiling fan, a potted plant, and a view of the city through large windows.

A dining area with outdoor seating, a table with a plate of food, a glass of water, and a person eating.

4. Hotel Plaza Herrera

San Felipe, 2.4 km from Biomuseo

Christina

₩326,715

₩622,935 total

includes taxes & fees

Oct 25 - Oct 26

A restaurant interior with checkered flooring, wooden tables, wicker chairs, and hanging wicker lamps.

A multi-level interior with a checkered floor, wooden railings, and potted plants.

A room with a brick wall, a wooden staircase, and hanging pendant lights.

An outdoor patio with a checkered floor, a bar area with cushioned seating, and a large umbrella providing shade.

5. Amarla Boutique Hotel Casco Viejo Adults Only

San Felipe, 2.5 km from Biomuseo

Shanae

₩249,052

₩273,957 total

includes taxes & fees

Nov 19 - Nov 20

A grand, illuminated building with a symmetrical facade, multiple balconies, and a prominent entrance.

A spacious bedroom with a large bed, a chandelier, a bathroom with a bathtub, and a dining area.

A restaurant interior with a large indoor tree, tables, chairs, and a display of potted plants.

A kitchen with a glass-top table, a coffee machine, wine glasses, and a bottle of wine.

6. La Concordia Boutique Hotel

San Felipe, 2.4 km from Biomuseo

Jadah

₩302,866

₩333,153 total

includes taxes & fees

Nov 6 - Nov 7

A spacious outdoor patio with wicker furniture, potted plants, and umbrellas providing shade.

A hotel with a covered entrance, multiple windows, and a balcony with plants.

A modern bar area with wooden bar stools, a black countertop, and a display of wine bottles.

A dimly lit restaurant with wooden decor, tables, and chairs arranged for dining.

7. Hotel San Felipe

San Felipe, 2.4 km from Biomuseo

Jordan

₩208,534

₩229,387 total

includes taxes & fees

Oct 27 - Oct 28

A spacious living area with a modern sofa, a wooden coffee table, and a staircase leading to an upper level.

A modern kitchen with white cabinets, a dining table with chairs, and a spiral staircase.

A spacious living area with a large TV, a stone accent wall, and a modern kitchen in the background.

A bedroom with a large bed, a ceiling fan, and multiple windows.

8. Casa Lefevre By Wynwood House

San Felipe, 2.6 km from Biomuseo

Selam

₩214,299

₩272,333 total

includes taxes & fees

Nov 2 - Nov 3

A spacious indoor area with high ceilings, large windows, and multiple dining tables.

A multi-story hotel with a central courtyard, balconies, and a view of the city skyline.

A spacious lobby with a tiled floor, large windows, and potted plants.

A white building with multiple balconies, large windows, and decorative railings.

9. American Trade Hotel

San Felipe, 2.4 km from Biomuseo

Ashleigh-Ann

₩326,972

₩359,669 total

includes taxes & fees

Nov 1 - Nov 2

A multi-story building with balconies, large windows, and a clear blue sky.

An outdoor patio with a white umbrella, lounge chairs, and a tiled floor.

A hallway with a brick wall, a blue door, and a chair with a cushion.

A living room with a sofa, a dining table with chairs, a potted plant, and a rug.

10. Las Clementinas

San Felipe, 2.5 km from Biomuseo

James

₩171,825

₩215,630 total

includes taxes & fees

Oct 28 - Oct 29

A multi-story building with balconies, arched windows, and decorative railings.

A building with a balcony and a street view.

A spacious lobby with a wooden staircase, multiple seating areas, and a reception desk.

A rooftop swimming pool with lounge chairs, potted plants, and a view of a city skyline including a prominent building with a dome.

11. Central Hotel Panama Casco Viejo

San Felipe, 2.5 km from Biomuseo

Yvonne

₩275,674

₩303,240 total

includes taxes & fees

Nov 18 - Nov 19

A hotel room with a bed, a desk with a computer, a chair, a mirror, and a staircase.

A spacious living area with a staircase leading to a second floor, a sofa, a TV, and a dining area.

A spacious living area with a staircase leading to a loft, a large mirror, and a television.

A living room with a patterned sofa, a matching ottoman, a large mirror, and a staircase leading to an outdoor area.

12. Hotel Bardot Boutique

San Felipe, 2.5 km from Biomuseo

Luz

₩122,323

₩134,555 total

includes taxes & fees

Nov 2 - Nov 3

A modern indoor pool area with clear blue water, lounge chairs, and a wall of plants.

A modern bedroom with a large window, a bed with white linens, a nightstand, and a painting on the wall.

A modern kitchen with a large window, a dining area with chairs, and a view of the city.

A modern kitchen with a central island, stainless steel appliances, and a dining area with black chairs.

13. Casco View Life Residences

Santa Ana, 2.4 km from Biomuseo

Arshak Andrew

₩111,409

₩162,482 total

includes taxes & fees

Oct 21 - Oct 22

A spacious living room with blue sofas, a marble coffee table, and framed pictures on the walls.

A bedroom with a large bed, white walls, and a view of a building through arched windows.

A blue building with arched windows and balconies, labeled 'Magnolia.'

14. Hotel Magnolia Boutique

San Felipe, 2.5 km from Biomuseo

Boris

₩108,050

₩118,855 total

includes taxes & fees

Oct 25 - Oct 26

A rooftop bar with a city skyline view, outdoor seating, and a bar area with bottles and glasses.

A hotel room with a large bed, a painting on the wall, a door, and a small table with a lamp.

A room with a kitchenette, a sofa, a bed, and a mural with the phrase "Just Breathe".

A modern living room with a purple wall, two abstract paintings, a white sofa with colorful cushions, a wooden coffee table with books and bottles, and patterned floor tiles.

15. Tantalo Hotel

San Felipe, 2.5 km from Biomuseo

Cynthia

₩110,311

₩121,342 total

includes taxes & fees

Nov 9 - Nov 10

A thatched-roof hut with wooden furniture and a bar area, surrounded by lush greenery and a paved walkway.

An outdoor patio area with wicker furniture and glass-top tables, surrounded by lush greenery and a view of the interior.

A hotel room with a bed, a ceiling fan, a TV, a refrigerator, and a window with curtains.

A living room with wicker furniture, a television, and a sliding glass door leading to a balcony with plants.

16. The Balboa Inn

Balboa, 2.7 km from Biomuseo

Rhonda

₩98,016

₩107,818 total

includes taxes & fees

Oct 22 - Oct 23

A resort with a pool area, lounge chairs, and a view of a bridge at night.

A hotel room with a bed, a TV on a wooden cabinet, a nightstand with a lamp, and a view of the outdoors through a glass door.

A bar area with a counter, stools, and a seating area with tables and chairs.

A reception desk with three staff members, a green patterned wall, a wooden reception area, and a large plant.

17. Radisson Hotel Panama Canal

Amador, 1.5 km from Biomuseo

Si Ming

₩112,607

₩123,868 total

includes taxes & fees

Nov 3 - Nov 4

A modern bathroom with a glass shower enclosure, a wooden door, and a herringbone-patterned floor.

A multi-story building with balconies adorned with string lights, a sign reading "ZABAH", and a storefront named "CORCHO".

A modern bathroom with a glass shower enclosure, a herringbone wooden floor, and a stone wall feature.

18. Corcho

San Felipe, 2.5 km from Biomuseo

Ashley

₩127,356

₩140,092 total

includes taxes & fees

Oct 31 - Nov 1

A modern kitchen with a dining area, large windows, and a view of the city.

A modern kitchen with a built-in oven and microwave, a living area with a sofa and ottomans, and a stone wall with a television.

A modern restaurant with a sushi bar, bar seating, and a mix of indoor and outdoor dining areas.

A modern kitchen with a built-in island, stainless steel appliances, and black bar stools.

19. La Cuadra by Wynwood House

El Chorrillo, 2.3 km from Biomuseo

Lise Jane

₩166,514

₩223,097 total

includes taxes & fees

Oct 21 - Oct 22

A balcony with a view of a cityscape, including a river and a bridge.

A high-rise building with a glass elevator shaft, a metal railing on the balcony, and a sign with the letters "OASIS".

A bedroom with a sloped ceiling, a bed with white bedding, a small wooden drying rack, a patterned rug, and an air conditioning unit.

A living room with a sofa, coffee table, TV, and artwork on the walls.

20. Oasis Hotel

San Felipe, 2.5 km from Biomuseo

Charles

₩79,255

₩87,180 total

includes taxes & fees

Nov 12 - Nov 13

View all properties

Compare popular hotels close to Biomuseo

Property	Property class	Guest rating
La Isabela Suites	10.0 Exceptional 212 reviews	View
Hotel La Compañía Casco Antiguo	9.8 Exceptional 363 reviews	View
Sofitel Legend Casco Viejo, Panama City	9.8 Exceptional 762 reviews	View
Hotel Plaza Herrera	9.8 Exceptional 50 reviews	View
Amarla Boutique Hotel Casco Viejo Adults Only	9.6 Exceptional 146 reviews	View

Top Biomuseo Hotel Reviews

Hotel Riu Plaza Panama

10/10 Excellent

"The Breakfast is amazing 😋"

Hotel San Felipe

10/10 Excellent

"Great location and awesome staff! Hotel San Felipe was perfect for exploring Casco Viejo! Large room and shower, patio area that we used to relax in the evenings and a great restaurant right across the street! If you plan to tour Casco Viejo this is a great place to stay! Looks and feels like the photos! You will not be disappointed:)"

Hotel Caracas - Casco Viejo

8/10 Good

"Room was clean and very basic. No frills! The bed and pillows were comfortable and the AC worked well. Good location."

Hotel Bardot Boutique

10/10 Excellent

"Excellent location to walk around, visit local attractions and restaurants in the old city."

Hotel La Compañía Casco Antiguo

10/10 Excellent

"Execelente hotel."

Radisson Hotel Panama Canal

10/10 Excellent

"The staff was very helpful and friendly. There is enough parking places. The room was very clean."

La Palma Experience

8/10 Good

"Recibimos buena atención, aunque se presentaron algunos inconvenientes como que el aire acondicionado no enfría a suficiente o que la presión de agua no llegaba a la habitacion, nos ofrecieron cambio de habitaciones lo cual nos permitió evaluar todas las opciones. Yo regreso, pero si me gustaría un menú más variado en sus desayunos, almuerzos y cenas."

La Cuadra by Wynwood House

10/10 Excellent

"Would definitely stay here again."

Casa Love by Wynwood House

10/10 Excellent

"The unit we stayed in was large and fully equipped, with a balcony and a full kitchen. The building was secure and conveniently located within walking distance to everything in casco viejo. There are lots of shops and restaurants nearby and we felt mostly safe walking around. The only issue we had was that the code to our lockbox didn’t work when we arrived. However, we texted the property staff and they were able to give us another code that worked right away. The internet in the unit worked fine, but be sure to have a data plan or eSIM so that you can connect with the property and order Ubers, especially when you first get in, as the WiFi in the airport can be very spotty."

Other attractions near Biomuseo

Amador Causeway

9.0/10 (1,902 reviews)

You can learn about the history of Ancon with a stop at Amador Causeway. Stroll along the seaside or visit the shops in this vibrant area.

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Amador Convention Center

9.2/10 (23 reviews)

Learn about the events happening at Amador Convention Center during your trip to Ancon. While in this walkable area, you can savor the top-notch restaurants.

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Punta Culebra Nature Center

9.0/10 (14 reviews)

Enjoy an outing to Punta Culebra Nature Center during your stay in Ancon. Stroll along the seaside in this vibrant area, or check out its top-notch restaurants.

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Maracana Stadium

8.0/10 (32 reviews)

Catch an event at Maracana Stadium during your trip to Panama City. Check out the shops and top-notch restaurants in this vibrant area.

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Smithsonian Tropical Research Institute Punta Culebra

9.2/10 (19 reviews)

You can spend time browsing the exhibits at Smithsonian Tropical Research Institute Punta Culebra in Ancon. Amble around this vibrant area's seaside and enjoy its top-notch restaurants.

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Danilo Perez Foundation

Explore the campus of Danilo Perez Foundation as part of your travels around Panama City. Check out the shops and top-notch restaurants in this vibrant area.

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Plaza de Francia

10.0/10 (1 review)

You can learn about the history of Panama City when you stop by Plaza de Francia. Check out the shops and top-notch restaurants in this vibrant area.

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Mola Museum

You can spend time browsing the exhibits at Mola Museum during your trip to Panama City. You can enjoy the bars while in the area.

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Frequently asked questions

What's the area like around Biomuseo?

Biomuseo is located in a vibrant area of Ancon known for its array of dining options and major shopping area. You'll find 1260 hotels and other accommodations within a few miles for a convenient home base.

What's the best hotel to stay near Biomuseo?

Radisson Hotel Panama Canal is one of the top choices for your stay based on our traveler data, and this hotel offers 2 outdoor pools and 2 restaurants. It's located just a short 0.9 mi (1.5 km) from Biomuseo. Another good choice is La Palma Experience, located just 0.7 mi (1.1 km) away.

How many hotels will I be able to find near Biomuseo?

Expedia has 1260 hotels and other accommodations a few miles from Biomuseo.

If I need to cancel the hotel reservation for my stay near Biomuseo, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to get the best options available near Biomuseo.

Where can I learn more about changing or cancelling my trip in the area near Biomuseo?

For more information about updating your stay near Biomuseo or cancelling it, click here.

What can I see and do near Biomuseo?

Interoceanic Canal Museum, Mola Museum, and Museum of History Panama feature a variety of fascinating exhibits to see while you're in town. Sights like Panama Canal Railway, Iglesia del Carmen, and Paseo de Las Bovedas are must-sees while exploring the area. You can catch a show at National Theater, Anita Villalaz Theater, and Amador Theater.

Find hotels near Biomuseo, Panama City from ₩87,180

Change your mind

Treat yourself

Be picky

Check prices for these dates

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Star rating

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Our top choices for Biomuseo hotels

1. La Isabela Suites

2. Hotel La Compañía Casco Antiguo

3. Sofitel Legend Casco Viejo, Panama City

4. Hotel Plaza Herrera

5. Amarla Boutique Hotel Casco Viejo Adults Only

6. La Concordia Boutique Hotel

7. Hotel San Felipe

8. Casa Lefevre By Wynwood House

9. American Trade Hotel

10. Las Clementinas

11. Central Hotel Panama Casco Viejo

12. Hotel Bardot Boutique

13. Casco View Life Residences

14. Hotel Magnolia Boutique

15. Tantalo Hotel

16. The Balboa Inn

17. Radisson Hotel Panama Canal

18. Corcho

19. La Cuadra by Wynwood House

20. Oasis Hotel

Compare popular hotels close to Biomuseo

Top Biomuseo Hotel Reviews

Hotel Riu Plaza Panama

Hotel San Felipe

Hotel Caracas - Casco Viejo

Hotel Bardot Boutique

Hotel La Compañía Casco Antiguo

Radisson Hotel Panama Canal

La Palma Experience

La Cuadra by Wynwood House

Casa Love by Wynwood House

Other attractions near Biomuseo

Amador Causeway

Amador Convention Center

Punta Culebra Nature Center

Maracana Stadium

Smithsonian Tropical Research Institute Punta Culebra

Danilo Perez Foundation

Plaza de Francia

Mola Museum

Frequently asked questions