Find Business Hotels in Casco Bay Islands, ME

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Check availability on Casco Bay Islands Business Hotels

Tonight
Dec 30 - Dec 31
Tomorrow
Dec 31 - Jan 1
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Our top choices for Casco Bay Islands business-friendly hotels

Lounge
Hyatt Place Portland Downtown - Old Port Square

Hyatt Place Portland Downtown - Old Port Square

Hyatt Place Portland Downtown - Old Port Square
3.0 star property
Downtown Portland
9.0 out of 10, Wonderful, (1303)
"This was a great stay! Brandon helped us with a room upgrade and the staff were super friendly the whole time. It was in a perfect location as well, easy walking to lots of great places for food and shopping! "
United States
Stetson
The price is ₩129,749
₩143,555 total
includes taxes & fees
Jan 21 - Jan 22, 2026
Hyatt Place Portland Downtown - Old Port Square
Garden
The Harraseeket Inn & Event House Freeport Downtown

The Harraseeket Inn & Event House Freeport Downtown

The Harraseeket Inn & Event House Freeport Downtown
3.5 star property
Freeport
9.4 out of 10, Exceptional, (879)
"Great stay "
United States
Sofia
The price is ₩155,764
₩169,789 total
includes taxes & fees
Jan 1 - Jan 2, 2026
The Harraseeket Inn & Event House Freeport Downtown
Restaurant
Germaine Inn South Portland

Germaine Inn South Portland

Germaine Inn South Portland
2.0 star property
Thorton Heights
7.6 out of 10, Good, (405)
"Amazing price, clean comfortable room, heated pool, free breakfast. "
United States
Sue
The price is ₩96,432
₩105,111 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Germaine Inn South Portland
Premium bedding, desk, blackout drapes, iron/ironing board
Portland Harbor Hotel

Portland Harbor Hotel

Portland Harbor Hotel
4.0 star property
Downtown Portland
9.2 out of 10, Wonderful, (1730)
"Great hotel in the perfect location. "
United States
Samantha
Portland Harbor Hotel
Porch
The Brunswick Hotel

The Brunswick Hotel

The Brunswick Hotel
3.0 star property
Brunswick
9.4 out of 10, Exceptional, (890)
"The room was very clean and the staff was so friendly!!! Definitely will stay here again!"
United States
Sherri
The Brunswick Hotel
Exterior
Long Creek Hotel by IHG

Long Creek Hotel by IHG

Long Creek Hotel by IHG
2.5 star property
South Portland
7.6 out of 10, Good, (1014)
"Enjoyed the stay"
United States
Farouq
The price is ₩111,515
₩121,551 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Long Creek Hotel by IHG
Exterior
Embassy Suites by Hilton Portland Maine

Embassy Suites by Hilton Portland Maine

Embassy Suites by Hilton Portland Maine
3.5 star property
Portland
9.4 out of 10, Exceptional, (1142)
"We love the Embassy Suites. Great room and dinner - breakfast is always good"
United States
Cynthia
The price is ₩141,781
₩156,867 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Embassy Suites by Hilton Portland Maine
Tapas bar
AC Hotel Portland Downtown/Waterfront, ME

AC Hotel Portland Downtown/Waterfront, ME

AC Hotel Portland Downtown/Waterfront, ME
3.5 star property
East Bayside
9.2 out of 10, Wonderful, (1006)
"Love this hotel. "
United States
Gabriella
The price is ₩130,101
₩143,943 total
includes taxes & fees
Jan 19 - Jan 20, 2026
AC Hotel Portland Downtown/Waterfront, ME
Aerial view
Hilton Garden Inn Portland Downtown Waterfront

Hilton Garden Inn Portland Downtown Waterfront

Hilton Garden Inn Portland Downtown Waterfront
3.0 star property
Downtown Portland
9.2 out of 10, Wonderful, (1004)
"Great service and clean hotel. Will stay again if In the area!"
United States
Christopher
The price is ₩143,013
₩158,230 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hilton Garden Inn Portland Downtown Waterfront
Exterior
Comfort Inn Brunswick

Comfort Inn Brunswick

Comfort Inn Brunswick
2.5 star property
Brunswick
9.0 out of 10, Wonderful, (1003)
"courteous staff, clean room. Small hotel but good place to stay."
United States
Susan
The price is ₩133,675
₩145,705 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Comfort Inn Brunswick
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Casco Bay Islands Hotel Reviews

Embassy Suites by Hilton Portland Maine

Embassy Suites by Hilton Portland Maine

10/10 Excellent
"Clean room, the breakfast with chef Joe in the morning is amazing. This is the best hotel in Portland area for the money, have stayed at many and this one never disappoints. "
Laurie 1-night trip
Posted 1 day ago
Embassy Suites by Hilton Portland Maine

Frequently asked questions

How much do business-friendly hotels in Casco Bay Islands cost?
Rates for business hotels in Casco Bay Islands range between ₩105,111 and ₩169,789 per night. Whatever your budget, Expedia can help you find the best space to get the job done. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Why book your business-friendly hotel in Casco Bay Islands with Expedia?
We're here to help you find the ideal business-friendly hotel for your upcoming work trip. From conference spaces and meeting rooms to on-site cafés and more, our stays have all the amenities you need to get the job done.
How can I find cheap business-friendly hotels in Casco Bay Islands?
Click on the "business friendly" filter, listed just under the "traveler experience" heading, to find cheap business-friendly hotels in Casco Bay Islands. Then refine your search by your per-night budget. Looking for properties away from the center is another easy way to save.