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Our top choices for Duke Regional Hospital hotels

A breakfast area with a chalkboard menu, a sign indicating breakfast starts here, and a variety of food items like waffles, oatmeal, and fruits.
A large indoor swimming pool with clear blue water, surrounded by beige tiled flooring and walls, with large windows allowing natural light.
A hotel room with a bed, a desk with a chair, a flat-screen TV, a microwave, and a mirror.
A narrow hallway with shelves stocked with snacks and beverages, leading to a room with a desk and chair.

1. Hampton Inn & Suites Durham/North I-85

Hampton Inn & Suites Durham/North I-85
2.2 km from Duke Regional Hospital
United States
Cindy
₩165,988
₩188,397 total
includes taxes & fees
Oct 26 - Oct 27
Hampton Inn & Suites Durham/North I-85
A hotel room with two beds, a flat-screen TV, a wooden headboard, and a carpeted floor.
A coffee station with two coffee machines, a coffee press, and various coffee-related items on a counter.
A breakfast buffet with a bakery section, a coffee station, and a sign indicating the availability of breakfast.
A Holiday Inn Express hotel with a modern design, featuring a prominent sign, multiple windows, and a well-lit entrance.

2. Holiday Inn Express Durham by IHG

Holiday Inn Express Durham by IHG
2.4 km from Duke Regional Hospital
United States
Kimberly R
₩157,592
₩178,867 total
includes taxes & fees
Oct 18 - Oct 19
Holiday Inn Express Durham by IHG
Exterior
A spacious hallway with wooden flooring, white walls, and multiple windows with blinds. There are two white chairs and a small table with a basket.
A reception desk with a 'Free Wi-Fi All Rooms' sign, a cash register, and a credit card reader.
A vending machine area with Pepsi and other beverage options, including a selection of juices and sodas.

3. Red Roof Inn Durham - Duke Univ Medical Center

Red Roof Inn Durham - Duke Univ Medical Center
2.3 km from Duke Regional Hospital
United States
Luis
₩84,887
₩98,652 total
includes taxes & fees
Oct 11 - Oct 12
Red Roof Inn Durham - Duke Univ Medical Center
A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.
A Hampton Inn & Suites hotel with a modern facade, multiple windows, and a parking lot.
An indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.
A modern hotel lobby with a reception desk, seating area, and a cityscape mural on the wall.

4. Hampton Inn & Suites Durham University Medical Center

Hampton Inn & Suites Durham University Medical Center
5 km from Duke Regional Hospital
United States
Donna
₩176,544
₩200,377 total
includes taxes & fees
Oct 11 - Oct 12
Hampton Inn & Suites Durham University Medical Center
An outdoor patio area with round tables and chairs, large umbrellas, and a glass door entrance.
A hotel room with two beds, a desk, a chair, a sofa, and a TV.
A modern living room with a fireplace, two sofas, a coffee table, and a TV mounted on the wall.
A multi-story hotel with a brick facade, large windows, and a well-lit entrance.

5. Fairfield by Marriott Inn & Suites Durham

Fairfield by Marriott Inn & Suites Durham
18.2 km from Duke Regional Hospital
United States
Yolanda
₩157,208
₩178,431 total
includes taxes & fees
Oct 11 - Oct 12
Fairfield by Marriott Inn & Suites Durham
A bar area with wooden bar stools, pendant lighting, and a counter with a glass display. There are tables and chairs in the background, and the room has a wooden floor.
A bar area with wooden shelves, a chalkboard menu, and various bottles.
A colonial-style building with a covered porch, multiple windows, and outdoor seating.
A hotel room with two beds, a sofa, a TV, and a bathroom visible through a door.

6. The Colonial Inn, an Ascend Collection Hotel

The Colonial Inn, an Ascend Collection Hotel
18.6 km from Duke Regional Hospital
United States
Veronica
₩146,958
₩166,797 total
includes taxes & fees
Oct 11 - Oct 12
The Colonial Inn, an Ascend Collection Hotel
A modern lobby with a central seating area, a TV screen, and a patterned wall.
A modern kitchen with a built-in refrigerator, a gray sofa, and a gray armchair.
A modern hotel room with a bed, bedside table, TV, and a small desk area.
An indoor swimming pool with clear water, surrounded by lounge chairs and potted plants.

7. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek
18.2 km from Duke Regional Hospital
United States
Maurice
₩159,889
₩181,074 total
includes taxes & fees
Oct 11 - Oct 12
Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek
A brick pathway flanked by neatly trimmed hedges leading to a building with a red facade and a grey roof.
A modern living room with two sofas facing a glass coffee table, a large window with curtains, and a brick wall.
An outdoor dining area with tables set for four, surrounded by a brick pathway and lush greenery.
A spacious lobby with a long corridor, comfortable seating areas, and large windows providing natural light.

8. Rizzo Center, a Destination by Hyatt Hotel

Rizzo Center, a Destination by Hyatt Hotel
17 km from Duke Regional Hospital
United States
Dale
₩264,044
₩299,689 total
includes taxes & fees
Oct 11 - Oct 12
Rizzo Center, a Destination by Hyatt Hotel
An indoor swimming pool with clear water, a no diving sign, and a seating area with chairs and tables.
A modern hotel lobby with a long dining table, multiple chairs, a sofa, and a bar area.
A modern kitchen with built-in shelves, a glass backsplash, and a variety of kitchenware.
A modern hotel lobby with a reception desk, several chairs, a large monitor, and pendant lighting.

9. Hyatt House Raleigh / RDU / Brier Creek

Hyatt House Raleigh / RDU / Brier Creek
17.8 km from Duke Regional Hospital
United States
Alejandro
₩159,780
₩180,950 total
includes taxes & fees
Oct 11 - Oct 12
Hyatt House Raleigh / RDU / Brier Creek
An outdoor seating area with wicker furniture and a stone fire pit.
An indoor swimming pool with clear water, a lifeguard chair, and a sign indicating no diving.
A modern hotel lobby with seating areas, large windows, and a dining section.
A conference room with a long table, chairs, and a modern chandelier.

10. Residence Inn Raleigh-Durham Airport/Brier Creek

Residence Inn Raleigh-Durham Airport/Brier Creek
16.6 km from Duke Regional Hospital
United States
Janet
₩188,757
₩213,767 total
includes taxes & fees
Oct 11 - Oct 12
Residence Inn Raleigh-Durham Airport/Brier Creek
An outdoor seating area with sofas, chairs, and a fire pit, adjacent to a modern building with large windows.
A modern kitchen with a central island, bar stools, wooden cabinets, and pendant lighting.
A modern living room with a fireplace, seating area, and a pool table.
A modern bar area with a long counter, multiple bar stools, and a large screen displaying a sports event.

11. JB Duke Hotel

JB Duke Hotel
6.2 km from Duke Regional Hospital
United States
samantha
₩270,351
₩306,855 total
includes taxes & fees
Oct 21 - Oct 22
JB Duke Hotel
A spacious lobby with high ceilings, a central fountain, and seating areas.
A modern bedroom with a large bed, a fireplace, a walk-in closet, and a bathroom with a round mirror and vanity.
An outdoor patio area with wicker furniture, stone pillars, and string lights.
A bar area with multiple liquor cabinets and hanging pendant lights.

12. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

Embassy Suites by Hilton Raleigh Durham Airport Brier Creek
18.2 km from Duke Regional Hospital
United States
Darren C.
₩215,405
₩243,947 total
includes taxes & fees
Oct 25 - Oct 26
Embassy Suites by Hilton Raleigh Durham Airport Brier Creek
A swimming pool with lounge chairs and a wooden fence.
A spacious lobby with a reception desk, seating area, and artwork on the walls.
A modern bar area with a refrigerated display, wooden bar counter, and seating.
A multi-story hotel with a modern design, featuring a prominent entrance with a glass canopy and an American flag.

13. Hyatt Place Durham Southpoint

Hyatt Place Durham Southpoint
16.1 km from Duke Regional Hospital
United States
Leslie
₩182,799
₩207,477 total
includes taxes & fees
Oct 11 - Oct 12
Hyatt Place Durham Southpoint
An outdoor seating area with wicker chairs and a large umbrella, a fire feature, and a view of the interior through glass walls.
A large indoor swimming pool with a skylight ceiling, clear glass walls, and a tiled floor.
A kitchen with a microwave, coffee maker, and a dishwasher.
A hotel room with a large bed, a bedside table with a lamp, a TV mounted on the wall, and a window with curtains.

14. DoubleTree Suites by Hilton Raleigh - Durham

DoubleTree Suites by Hilton Raleigh - Durham
14.2 km from Duke Regional Hospital
United States
Stephen
₩155,447
₩176,432 total
includes taxes & fees
Oct 5 - Oct 6
DoubleTree Suites by Hilton Raleigh - Durham
A hotel entrance with a stone facade, large wooden doors, and a view into the interior.
A dining area with a chandelier, tables, chairs, and a Christmas tree.
A person performing a yoga pose outdoors with trees and a golf course in the background.
An indoor swimming pool with clear blue water, surrounded by lounge chairs and potted plants.

15. Washington Duke Inn & Golf Club

Washington Duke Inn & Golf Club
6.6 km from Duke Regional Hospital
United States
Lowell
₩346,430
₩393,198 total
includes taxes & fees
Sep 30 - Oct 1
Washington Duke Inn & Golf Club
A lobby with a green sofa, yellow chairs, a coffee table with drinks, and a window with plants.
An indoor swimming pool with clear glass walls, a tiled floor, and a seating area with chairs and a table.
A business center with wooden paneling, multiple workstations, and framed artwork on the walls.
A bar area with a granite countertop, wooden chairs, and a large television screen.

16. Hilton Garden Inn Durham/University Medical Center

Hilton Garden Inn Durham/University Medical Center
9th Street District, 4 km from Duke Regional Hospital
United States
Hal
₩198,750
₩225,582 total
includes taxes & fees
Oct 11 - Oct 12
Hilton Garden Inn Durham/University Medical Center
An outdoor seating area with a circular fire pit surrounded by wicker chairs and a table.
An indoor swimming pool with a 3 FT depth marker, a wheelchair-accessible chair, a potted plant, and a view of the outside through large windows.
A modern hotel lobby with a mix of seating areas, a bar, and a large wall-mounted TV.
A reception area with a large screen displaying a sea view, a bench, and a sign indicating the location as Marriott Bonvoy.

17. SpringHill Suites by Marriott Durham Chapel Hill

SpringHill Suites by Marriott Durham Chapel Hill
12.6 km from Duke Regional Hospital
United States
Logan
₩173,158
₩196,534 total
includes taxes & fees
Oct 4 - Oct 5
SpringHill Suites by Marriott Durham Chapel Hill
A spacious, elegantly decorated interior with a central round table, high ceilings, and classic architectural columns.
A banquet hall with round tables, chandeliers, and floral centerpieces.
A spacious living room with a sofa, armchairs, a coffee table, and a chandelier.
A large, historic building with a central courtyard, columns, and a brick facade.

18. The Carolina Inn, a Destination by Hyatt Hotel

The Carolina Inn, a Destination by Hyatt Hotel
19.9 km from Duke Regional Hospital
United States
Tony
₩487,719
₩553,560 total
includes taxes & fees
Oct 12 - Oct 13
The Carolina Inn, a Destination by Hyatt Hotel
An outdoor patio with wicker furniture, a stone fire pit, and a brick building in the background.
A gym with treadmills, elliptical machines, a bench press, and a blue balance board.
A hotel room with two beds, a desk, a TV, and a sofa.
A spacious lobby with a reception desk, seating area, and a beverage kiosk.

19. Residence Inn Durham McPherson/Duke University Medical Cntr

Residence Inn Durham McPherson/Duke University Medical Cntr
Trinity Park, 4.1 km from Duke Regional Hospital
United States
Patricia
₩237,138
₩269,151 total
includes taxes & fees
Oct 11 - Oct 12
Residence Inn Durham McPherson/Duke University Medical Cntr
Restaurant
A reception area with two wooden reception desks, a potted plant, and a computer on the wall.
An indoor swimming pool with clear water, a lifeguard chair, and a sign indicating no diving.
A hotel room with two beds, a desk, a chair, a TV, and a bathroom.

20. Courtyard Raleigh-Durham Airport/Brier Creek

Courtyard Raleigh-Durham Airport/Brier Creek
16.6 km from Duke Regional Hospital
United States
eidy
₩181,418
₩205,455 total
includes taxes & fees
Oct 25 - Oct 26
Courtyard Raleigh-Durham Airport/Brier Creek
View all properties

Compare popular hotels close to Duke Regional Hospital

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A breakfast area with a chalkboard menu, a sign indicating breakfast starts here, and a variety of food items like waffles, oatmeal, and fruits.
Hampton Inn & Suites Durham/North I-85
9.0
Wonderful
1,006 reviews
View
A hotel room with two beds, a flat-screen TV, a wooden headboard, and a carpeted floor.
Holiday Inn Express Durham by IHG
8.8
Excellent
1,005 reviews
View
Exterior
Red Roof Inn Durham - Duke Univ Medical Center
6.8
1,001 reviews
View
A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.
Hampton Inn & Suites Durham University Medical Center
9.6
Exceptional
563 reviews
View
An outdoor patio area with round tables and chairs, large umbrellas, and a glass door entrance.
Fairfield by Marriott Inn & Suites Durham
9.6
Exceptional
52 reviews
View

Top Duke Regional Hospital Hotel Reviews

Courtyard Durham Near Duke University/Downtown

Courtyard Durham Near Duke University/Downtown

10/10 Excellent
"Room was clean and comfortable. I stay at this hotel every visit to Durham. I go to Duke hospital every 6 months, so this hotel is close and convenient."
Nicole 1-night trip
Posted 1 hour ago
Courtyard Durham Near Duke University/Downtown
Millennium Hotel Durham

Millennium Hotel Durham

10/10 Excellent
"My wife and I enjoyed our stay at the Millennium. The room and hotel were very clean, well-maintained, and comfortable, and we could locate handy parking at all times. We found the lobby, restaurant, bar, and grounds quite attractive. We didn't avail ourselves of the pool, but it looked clean and appealing. The bar was enjoyable, although the bartender loaded the drinks with so much ice they ended up -very- watered down, so we didn't order any beyond the first. Overall, the positives far outweighed the negatives, so we'd be happy to stay here again."
Stephen 1-night trip
Posted 20 hours ago
Millennium Hotel Durham
Comfort Inn & Suites Durham near Duke University

Comfort Inn & Suites Durham near Duke University

10/10 Excellent
"Clean room got coffees in my room and husband had breakfast in te morning before his hospital appointment"
Michael 1-night trip
Posted 1 day ago
Comfort Inn & Suites Durham near Duke University
Unscripted Durham, Part of JDV by Hyatt

Unscripted Durham, Part of JDV by Hyatt

10/10 Excellent
"I will stay here again—it’s so centrally located, walking distance to tons of shops, restaurants, cafes, and small businesses. Everyone was so friendly and it was easy to come and go. My room was very clean. I travel a lot, and was delighted to find soft beds and towels. Really fun spot."
Amy 2-night trip
Posted 2 days ago
Unscripted Durham, Part of JDV by Hyatt
The Lodge at Duke Medical Center

The Lodge at Duke Medical Center

10/10 Excellent
"My stay was great!"
Kenneth 1-night trip
Posted 2 days ago
The Lodge at Duke Medical Center
Holiday Inn Express Durham by IHG

Holiday Inn Express Durham by IHG

10/10 Excellent
"clean"
SAMUEL 1-night trip
Posted 2 days ago
Holiday Inn Express Durham by IHG
Hampton Inn & Suites Durham/North I-85

Hampton Inn & Suites Durham/North I-85

10/10 Excellent
"The hotel was well maintaned and the personnel were friendly."
Cindy 1-night trip
Posted 3 days ago
Hampton Inn & Suites Durham/North I-85

Frequently asked questions

What's the area like around Duke Regional Hospital?
Duke Regional Hospital is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, check out the 10 hotels and other accommodations you'll find within a mile.
Where is the best place to stay close to Duke Regional Hospital?
Courtyard Durham Near Duke University/Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and free parking. It's located 2.2 mi (3.5 km) from Duke Regional Hospital. Other good choices within a few miles include Holiday Inn Express Durham by IHG and Red Roof Inn Durham - Duke Univ Medical Center.
How many hotels can I expect to find near Duke Regional Hospital?
Expedia has 10 hotels and other accommodations within a mile from Duke Regional Hospital.
If I need to cancel the hotel reservation for my stay near Duke Regional Hospital, will I receive a refund?
Yes! Most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to get the best deals near Duke Regional Hospital.
Where can I learn more about changing or cancelling my trip in the area near Duke Regional Hospital?
To find more details about changing or cancelling your stay near Duke Regional Hospital, click here.
What can I see and do near Duke Regional Hospital?
You might want to spend some time browsing the exhibits at Museum of Life and Science, Nasher Museum of Art at Duke University, or Bennett Place. While you're exploring, swing by American Tobacco Campus, Cameron Indoor Stadium, and Wallace Wade Stadium to learn a bit about the area. You can enjoy live performances at Carolina Theatre and Common Ground Theatre.