Find hotels near Duke Regional Hospital, Raleigh from ₩97,427

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Dec 29 - Dec 30
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Our top choices for Duke Regional Hospital hotels

Lobby
Hampton Inn & Suites Durham/North I-85

Hampton Inn & Suites Durham/North I-85

Hampton Inn & Suites Durham/North I-85
2.5 star property
2.2 km from Duke Regional Hospital
9.0 out of 10, Wonderful, (1004)
"Very clean hotel. Staff was very pleasant and helpful."
United States
Brenda
The price is ₩164,320
₩186,502 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hampton Inn & Suites Durham/North I-85
Free buffet breakfast
Holiday Inn Express Durham by IHG

Holiday Inn Express Durham by IHG

Holiday Inn Express Durham by IHG
2.5 star property
2.4 km from Duke Regional Hospital
8.8 out of 10, Excellent, (958)
"Room was clean, staff was courteous"
United States
John
The price is ₩139,841
₩158,727 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express Durham by IHG
Lobby
Red Roof Inn Durham - Duke Univ Medical Center

Red Roof Inn Durham - Duke Univ Medical Center

Red Roof Inn Durham - Duke Univ Medical Center
2.0 star property
2.3 km from Duke Regional Hospital
6.8 out of 10, (1003)
"Good motel...clean, easy acess "
United States
Howard
The price is ₩83,676
₩97,427 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Red Roof Inn Durham - Duke Univ Medical Center
Premium bedding, desk, blackout drapes, iron/ironing board
Comfort Inn & Suites Durham near Duke University

Comfort Inn & Suites Durham near Duke University

Comfort Inn & Suites Durham near Duke University
2.5 star property
Croasdaile Farm Master, 3.3 km from Duke Regional Hospital
8.6 out of 10, Excellent, (1003)
"Friendly staff, clean room, nice breakfast"
United States
Jessica
The price is ₩135,588
₩153,893 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Comfort Inn & Suites Durham near Duke University
Meeting facility
Hilton Garden Inn Durham/University Medical Center

Hilton Garden Inn Durham/University Medical Center

Hilton Garden Inn Durham/University Medical Center
3.0 star property
9th Street District, 4.1 km from Duke Regional Hospital
9.2 out of 10, Wonderful, (1000)
"Just right for an overnight business trip "
United States
Cody
The price is ₩138,760
₩157,492 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hilton Garden Inn Durham/University Medical Center
Reception
Hampton Inn & Suites Durham University Medical Center

Hampton Inn & Suites Durham University Medical Center

Hampton Inn & Suites Durham University Medical Center
2.5 star property
5 km from Duke Regional Hospital
9.6 out of 10, Exceptional, (403)
"Great breakfast, clean rooms and beds "
United States
Fabiola B
The price is ₩165,791
₩188,174 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Hampton Inn & Suites Durham University Medical Center
Courtyard
Residence Inn Durham McPherson/Duke University Medical Cntr

Residence Inn Durham McPherson/Duke University Medical Cntr

Residence Inn Durham McPherson/Duke University Medical Cntr
3.0 star property
Trinity Park, 4.1 km from Duke Regional Hospital
9.2 out of 10, Wonderful, (461)
"Hotel was great - very friendly staff."
United States
Lisa
The price is ₩193,026
₩219,085 total
includes taxes & fees
Jan 27 - Jan 28, 2026
Residence Inn Durham McPherson/Duke University Medical Cntr
Premium bedding, desk, blackout drapes, iron/ironing board
The Durham Hotel

The Durham Hotel

The Durham Hotel
4.0 star property
Downtown Durham, 4.5 km from Duke Regional Hospital
9.0 out of 10, Wonderful, (645)
"Great stay. Very nice boutique hotel. "
United States
nadav
The price is ₩268,163
₩304,365 total
includes taxes & fees
Jan 1 - Jan 2, 2026
The Durham Hotel
Front of property - evening/night
University Inn Durham next to Duke University Medical Center

University Inn Durham next to Duke University Medical Center

University Inn Durham next to Duke University Medical Center
2.0 star property
4.5 km from Duke Regional Hospital
8.8 out of 10, Excellent, (1002)
"Great place"
United States
Chase
The price is ₩164,349
₩186,551 total
includes taxes & fees
Dec 30 - Dec 31
University Inn Durham next to Duke University Medical Center
BBQ/picnic area
Courtyard Durham Near Duke University/Downtown

Courtyard Durham Near Duke University/Downtown

Courtyard Durham Near Duke University/Downtown
3.0 star property
Croasdaile Farm Master, 3.4 km from Duke Regional Hospital
8.2 out of 10, Very Good, (1000)
"Great place "
United States
Silvia
The price is ₩139,697
₩158,557 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Courtyard Durham Near Duke University/Downtown
BBQ/picnic area
AC Hotel Durham

AC Hotel Durham

AC Hotel Durham
3.0 star property
5.4 km from Duke Regional Hospital
9.2 out of 10, Wonderful, (621)
"Room was very clean, staff very helpful and nice. "
United States
Tia
The price is ₩170,332
₩193,327 total
includes taxes & fees
Jan 4 - Jan 5, 2026
AC Hotel Durham
Terrace/patio
SpringHill Suites by Marriott Durham City View

SpringHill Suites by Marriott Durham City View

SpringHill Suites by Marriott Durham City View
3.5 star property
5.4 km from Duke Regional Hospital
9.2 out of 10, Wonderful, (457)
"Extremely clean room, nice fragrance throughout the hotel, and friendly staff."
United States
Mary
The price is ₩135,516
₩153,811 total
includes taxes & fees
Jan 4 - Jan 5, 2026
SpringHill Suites by Marriott Durham City View
Daily cooked-to-order breakfast (USD 19.95 per person)
Durham Marriott City Center

Durham Marriott City Center

Durham Marriott City Center
3.5 star property
Downtown Durham, 4.5 km from Duke Regional Hospital
8.8 out of 10, Excellent, (824)
"The room was clean. The staff was very helpful and the food was good. "
United States
Tia
The price is ₩194,624
₩220,897 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Durham Marriott City Center
Property amenity
Aloft Durham Downtown

Aloft Durham Downtown

Aloft Durham Downtown
3.0 star property
American Tobacco District, 4.9 km from Duke Regional Hospital
9.0 out of 10, Wonderful, (731)
"Very friendly staff, very clean and convenient location"
United States
Robert
The price is ₩268,149
₩304,349 total
includes taxes & fees
Jan 25 - Jan 26, 2026
Aloft Durham Downtown
Front of property
The Lodge at Duke Medical Center

The Lodge at Duke Medical Center

The Lodge at Duke Medical Center
3.0 star property
4.6 km from Duke Regional Hospital
8.4 out of 10, Very Good, (1002)
"Room was clean and great customer service. "
United States
Anne
The price is ₩185,974
₩211,079 total
includes taxes & fees
Dec 30 - Dec 31
The Lodge at Duke Medical Center
Indoor pool
Washington Duke Inn & Golf Club

Washington Duke Inn & Golf Club

Washington Duke Inn & Golf Club
4.0 star property
6.6 km from Duke Regional Hospital
9.4 out of 10, Exceptional, (1009)
"Beautiful hotel. The staff is fabulous! Went out of their way to make our stay memorable."
United States
Lisa
The price is ₩230,666
₩261,804 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Washington Duke Inn & Golf Club
Interior entrance
21c Museum Hotel Durham

21c Museum Hotel Durham

21c Museum Hotel Durham
4.0 star property
Downtown Durham, 4.6 km from Duke Regional Hospital
8.4 out of 10, Very Good, (1000)
"Amazing staff, comfortable rooms, best shower, convenient location. "
United States
Lauren
The price is ₩231,603
₩270,077 total
includes taxes & fees
Jan 18 - Jan 19, 2026
21c Museum Hotel Durham
Exterior
Unscripted Durham, Part of JDV by Hyatt

Unscripted Durham, Part of JDV by Hyatt

Unscripted Durham, Part of JDV by Hyatt
3.5 star property
Downtown Durham, 4.5 km from Duke Regional Hospital
8.2 out of 10, Very Good, (1003)
"We stay here at least annually and always will. "
United States
Paul
The price is ₩183,091
₩232,330 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Unscripted Durham, Part of JDV by Hyatt
Seasonal outdoor pool, open 9:00 AM to 9:00 PM, pool umbrellas
Hilton Durham near Duke University

Hilton Durham near Duke University

Hilton Durham near Duke University
3.5 star property
5.4 km from Duke Regional Hospital
8.4 out of 10, Very Good, (1004)
"Great stay"
United States
Daniel
The price is ₩152,499
₩173,086 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Hilton Durham near Duke University
Garden
Arrowhead Inn

Arrowhead Inn

Arrowhead Inn
4.5 star property
8.9 km from Duke Regional Hospital
9.8 out of 10, Exceptional, (119)
"Bed was very comfortable, breakfast was yummy, and the surroundings were beautiful"
United States
Ronald
The price is ₩282,854
₩321,029 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Arrowhead Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Duke Regional Hospital Hotel Reviews

Hampton Inn & Suites Durham/North I-85

Hampton Inn & Suites Durham/North I-85

10/10 Excellent
"Very clean hotel. Staff was very pleasant and helpful."
Brenda 1-night trip
Posted 2 days ago
Hampton Inn & Suites Durham/North I-85

Hotels near other Duke Regional Hospital attractions

Sennett's hole is a swimming hole accessed from the west point outpost on the eno river. There are lots of rocks to lounge on on one side, and a rope swing on the other. It's great spot to hang out!
Photo by Nikki Benson
Open Photo by Nikki Benson

West Point on the Eno

Explore the great outdoors at West Point on the Eno, a lovely green space in Durham. Attend a sporting event or visit the stunning cathedral in this family-friendly area.
See properties
Brightleaf is part of downtown Durham, NC's renaissance. Old tobacco warehouses have found new life as shops and restaurants.
Photo by Jeff Bechtel
Open Photo by Jeff Bechtel

Brightleaf Square

You can browse for the perfect souvenirs at Brightleaf Square during your visit to Durham. Discover the lively festivals and stunning cathedral in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Duke Regional Hospital?
Duke Regional Hospital is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, check out the 11 hotels and other accommodations you'll find within a mile.
Where is the best place to stay close to Duke Regional Hospital?
Hampton Inn & Suites Durham/North I-85 is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 1.3 mi (2.2 km) from Duke Regional Hospital. Other good choices within a few miles include Comfort Inn & Suites Durham near Duke University and Holiday Inn Express Durham by IHG.
How many hotels can I expect to find near Duke Regional Hospital?
Expedia has 11 hotels and other accommodations within a mile from Duke Regional Hospital.
If I need to cancel the hotel reservation for my stay near Duke Regional Hospital, will I receive a refund?
Yes! Most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to get the best deals near Duke Regional Hospital.
Where can I learn more about changing or cancelling my trip in the area near Duke Regional Hospital?
To find more details about changing or cancelling your stay near Duke Regional Hospital, click here.
What can I see and do near Duke Regional Hospital?
You might want to spend some time browsing the exhibits at Museum of Life and Science, Nasher Museum of Art at Duke University, or Bennett Place. While you're exploring, swing by American Tobacco Campus, Cameron Indoor Stadium, and Wallace Wade Stadium to learn a bit about the area. You can watch performances at Carolina Theatre, Durham Performing Arts Center, and Manbites Dog Theater if you're interested in local theater.