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Check availability on Florida Keys Adults Only Resorts & Hotels

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Our top choices for Florida Keys adults-only hotels

1. Kona Kai Resort and Gallery - Adults Only

Kona Kai Resort and Gallery - Adults Only
2.5 star property
Rock Harbor
9.8 out of 10, Exceptional, (365 reviews)
"We will make this an annual trip. A great place. Thank you for making it a great stay"
United States
Billy
The price is ₩190,694
₩252,214 total
includes taxes & fees
Nov 2 - Nov 3
Kona Kai Resort and Gallery - Adults Only

2. Duval House

Duval House
3.0 star property
Old Town Key West
9.6 out of 10, Exceptional, (1,130 reviews)
"Great stay!"
United States
Dennis
The price is ₩212,998
₩268,425 total
includes taxes & fees
Nov 2 - Nov 3
Duval House

3. The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only
3.0 star property
Old Town Key West
8.4 out of 10, Very good, (1,456 reviews)
"Great place."
United States
Craig
The price is ₩215,863
₩303,142 total
includes taxes & fees
Nov 2 - Nov 3
The Southernmost Inn - Adults Only

4. Heron House - Adult Only

Heron House - Adult Only
3.5 star property
Old Town Key West
9.2 out of 10, Wonderful, (1,142 reviews)
"Great location!"
United States
Meilyn
The price is ₩232,931
₩308,799 total
includes taxes & fees
Nov 1 - Nov 2
Heron House - Adult Only

5. Tropical Inn

Tropical Inn
3.5 star property
Old Town Key West
9.4 out of 10, Exceptional, (450 reviews)
"We will definitely stay here again!"
United States
Natalie
The price is ₩207,448
₩266,874 total
includes taxes & fees
Nov 2 - Nov 3
Tropical Inn

6. Southernmost House - Adult Exclusive

Southernmost House - Adult Exclusive
4.0 star property
Old Town Key West
9.4 out of 10, Exceptional, (1,000 reviews)
"staff was super friendly and accomodating"
United States
Janet
The price is ₩261,626
₩463,874 total
includes taxes & fees
Nov 8 - Nov 9
Southernmost House - Adult Exclusive

7. The Grand Guesthouse

The Grand Guesthouse
2.5 star property
Old Town Key West
9.6 out of 10, Exceptional, (1,000 reviews)
"Fun apartment style living in Key West…fun little patio with coffee and continental breakfast. Make sure you look at the check in hours :) great spot makes you feel local"
United States
Justyn
The price is ₩279,155
₩347,539 total
includes taxes & fees
Nov 23 - Nov 24
The Grand Guesthouse

8. Douglas House - Adults Only

Douglas House - Adults Only
3.0 star property
Old Town Key West
9.8 out of 10, Exceptional, (573 reviews)
"Loved our stay! I would definitely stay there again."
United States
Maricela
The price is ₩210,844
₩260,918 total
includes taxes & fees
Nov 3 - Nov 4
Douglas House - Adults Only

9. Seascape Tropical Inn - Adult Exclusive

Seascape Tropical Inn - Adult Exclusive
3.0 star property
Old Town Key West
9.0 out of 10, Wonderful, (484 reviews)
"This was our first time staying here and I will say that it was a pleasure. Staff were friendly and quite helpful. Location couldn’t be better as you’re right off of Duval St. I highly recommend as we will be staying here again in the future."
United States
Evan
The price is ₩234,432
₩331,554 total
includes taxes & fees
Nov 2 - Nov 3
Seascape Tropical Inn - Adult Exclusive

10. L'Habitation Guest House - Adults Only

L'Habitation Guest House - Adults Only
2.5 star property
Key West Historic District
9.4 out of 10, Exceptional, (1,003 reviews)
"Everything was amazing. Drew runs a beautiful place."
United States
Matthew
The price is ₩195,657
₩220,111 total
includes taxes & fees
Nov 1 - Nov 2
L'Habitation Guest House - Adults Only
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Florida Keys

Discover top Florida Keys attractions

The Florida Keys offer an exceptional blend of adventure and relaxation, perfect for families seeking quality experiences. Start your journey at John Pennekamp Coral Reef State Park in Key Largo, where you can snorkel or dive amidst vibrant coral reefs filled with marine life—perfect for the adventurous family. Next, visit the iconic Seven Mile Bridge, where breathtaking views of the turquoise waters await; it’s a fantastic spot for a family photo op. Don’t miss the opportunity to explore the charming streets of Key West, where you can visit the Ernest Hemingway Home and Museum, offering a glimpse into the life of the legendary author. For a unique experience, try a sunset sail with a local charter, allowing you to soak in the stunning sunset views while sipping on refreshing drinks. When it comes to accommodations, consider staying in the vibrant area of Islamorada, known as the Sport Fishing Capital of the World. Here, you’ll find a range of waterfront resorts with family-friendly amenities, ensuring a comfortable and pampered stay. With attentive service and easy access to both relaxation and adventure, your family will create unforgettable memories in this beautiful region.

Top Florida Keys Hotel Reviews