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Our top choices for Isle of Palms hotels

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
Isle of Palms
9.4 out of 10, Exceptional, (467 reviews)
"Clean room, amazing staff great location "
United States
Darlene
The price is ₩253,097
₩287,266 total
includes taxes & fees
Feb 28 - Mar 1
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
3.0 star property
3.3 km from Isle of Palms
9.2 out of 10, Wonderful, (1,003 reviews)
"Hotel was clean, breakfast was perfect."
United States
Kurt
The price is ₩195,246
₩221,605 total
includes taxes & fees
Mar 1 - Mar 2
Holiday Inn Express Jacksonville Beach by IHG

Quality Inn Atlantic Beach - Mayo Clinic Jax Area

Quality Inn Atlantic Beach - Mayo Clinic Jax Area
2.5 star property
9 km from Isle of Palms
7.8 out of 10, Good, (1,001 reviews)
"This was a spectacular stay"
United States
Lance
The price is ₩143,181
₩162,510 total
includes taxes & fees
Feb 25 - Feb 26
Quality Inn Atlantic Beach - Mayo Clinic Jax Area

Best Western Mayport Inn & Suites

Best Western Mayport Inn & Suites
2.5 star property
8.8 km from Isle of Palms
7.8 out of 10, Good, (728 reviews)
"Staff was very kind check in ,check out and breakfast room not so clean and lots of damaged things , breakfast place was clean Thank you "
United States
Kimberly
The price is ₩152,911
₩173,555 total
includes taxes & fees
Feb 24 - Feb 25
Best Western Mayport Inn & Suites

Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront
3.0 star property
5 km from Isle of Palms
9.2 out of 10, Wonderful, (2,654 reviews)
"Everyone was friendly, kind and went out of their way to help with anything we needed. Great staff, great stay!"
United States
Barbara
The price is ₩247,862
₩281,323 total
includes taxes & fees
Mar 4 - Mar 5
Hampton Inn Jacksonville Beach/Oceanfront

Casa Marina Hotel

Casa Marina Hotel
3.0 star property
4.6 km from Isle of Palms
8.4 out of 10, Very Good, (1,006 reviews)
"The Casa Marina hotel is very eclectic. The hotel is great for a lot of reasons. It is on the beach, the staff is exceptional, and it is located in a great area for dinning and shopping. Love this hotel!"
United States
Thomas
Casa Marina Hotel

Fairfield Inn & Suites by Marriott Jacksonville Beach

Fairfield Inn & Suites by Marriott Jacksonville Beach
3.0 star property
5 km from Isle of Palms
8.6 out of 10, Excellent, (902 reviews)
"Spacious clean rooms Good breakfast options Friendly staff Close to beach; fantastic location Newly renovated hotel property Paid parking but felt safe "
United States
Krunal
The price is ₩183,676
₩208,473 total
includes taxes & fees
Mar 1 - Mar 2
Fairfield Inn & Suites by Marriott Jacksonville Beach

Candlewood Suites Jacksonville - Mayport by IHG

Candlewood Suites Jacksonville - Mayport by IHG
2.5 star property
8 km from Isle of Palms
9.0 out of 10, Wonderful, (261 reviews)
"It's location was perfect and not too far from the places that I needed to go."
United States
Ian
The price is ₩177,891
₩201,905 total
includes taxes & fees
Mar 1 - Mar 2
Candlewood Suites Jacksonville - Mayport by IHG

Four Points by Sheraton Jacksonville Beachfront

Four Points by Sheraton Jacksonville Beachfront
3.0 star property
4.3 km from Isle of Palms
9.0 out of 10, Wonderful, (1,005 reviews)
"Beds very comfortable. Check-in seamless. I loved my stay."
United States
Pizza
The price is ₩282,023
₩320,097 total
includes taxes & fees
Mar 22 - Mar 23
Four Points by Sheraton Jacksonville Beachfront

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
4.6 km from Isle of Palms
9.0 out of 10, Wonderful, (3,697 reviews)
"Yes room was spotless and staff was amazing!"
United States
Martina
The price is ₩193,945
₩220,128 total
includes taxes & fees
Mar 1 - Mar 2
Margaritaville Jacksonville Beach

TownePlace Suites by Marriott® Jacksonville Mayport

TownePlace Suites by Marriott® Jacksonville Mayport
3.0 star property
9.7 km from Isle of Palms
9.8 out of 10, Exceptional, (79 reviews)
"New, clean room and nice breakfast."
United States
Gregory
The price is ₩167,767
₩190,416 total
includes taxes & fees
Mar 1 - Mar 2
TownePlace Suites by Marriott® Jacksonville Mayport

Holiday Inn Express & Suites Jacksonville - Atlantic Beach by IHG

Holiday Inn Express & Suites Jacksonville - Atlantic Beach by IHG
2.5 star property
7.8 km from Isle of Palms
8.6 out of 10, Excellent, (1,003 reviews)
"Our stay was great"
United States
Shawna
The price is ₩155,040
₩175,971 total
includes taxes & fees
Mar 1 - Mar 2
Holiday Inn Express & Suites Jacksonville - Atlantic Beach by IHG

Salt Air Inn & Suites

Salt Air Inn & Suites
2.5 star property
6.5 km from Isle of Palms
9.8 out of 10, Exceptional, (442 reviews)
"Amazing hotel absolute gem for Jacksonville beach "
United States
Justin
Salt Air Inn & Suites

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
4.4 km from Isle of Palms
9.0 out of 10, Wonderful, (1,009 reviews)
"Great location, breakfast was delicious "
United States
Paul
The price is ₩173,538
₩196,968 total
includes taxes & fees
Mar 22 - Mar 23
Best Western Oceanfront

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
3.7 km from Isle of Palms
9.0 out of 10, Wonderful, (1,039 reviews)
"Clean room, good breakfast and location"
United States
Jesus
The price is ₩188,348
₩213,775 total
includes taxes & fees
Mar 1 - Mar 2
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront
4.0 star property
4.5 km from Isle of Palms
9.0 out of 10, Wonderful, (641 reviews)
"The hotel was great! Very clean room and staff were very courteous and professional"
United States
Mike
The price is ₩269,006
₩305,323 total
includes taxes & fees
Mar 1 - Mar 2
Springhill Suites By Marriott Jacksonville Beach Oceanfront

Fairfield Inn & Suites Jacksonville Airport

Fairfield Inn & Suites Jacksonville Airport
3.0 star property
31.5 km from Isle of Palms
8.4 out of 10, Very Good, (1,000 reviews)
"Nice hotel for our short stay. "
United States
Teresa
The price is ₩180,928
₩205,353 total
includes taxes & fees
Feb 26 - Feb 27
Fairfield Inn & Suites Jacksonville Airport

Comfort Suites Jacksonville Airport

Comfort Suites Jacksonville Airport
3.0 star property
31.3 km from Isle of Palms
8.2 out of 10, Very Good, (933 reviews)
"Nice comfortable rooms everything was great "
United States
Dawn
The price is ₩153,594
₩174,330 total
includes taxes & fees
Mar 1 - Mar 2
Comfort Suites Jacksonville Airport

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.7 km from Isle of Palms
9.0 out of 10, Wonderful, (1,023 reviews)
"Very friendly staff, good restaurants in hotel and in the complex "
United States
Richard
The price is ₩224,143
₩249,919 total
includes taxes & fees
Mar 17 - Mar 18
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Element Jacksonville Beach

Element Jacksonville Beach
3.0 star property
4.2 km from Isle of Palms
9.6 out of 10, Exceptional, (537 reviews)
"Great place (and location)!"
United States
Dale
The price is ₩195,246
₩221,604 total
includes taxes & fees
Mar 22 - Mar 23
Element Jacksonville Beach
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Isle of Palms

Find the best Isle of Palms areas and neighborhoods for the activities you enjoy most.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Downtown Jacksonville

Historic core with major corporations, Downtown Jacksonville offers diverse culinary and nightlife experiences at The Elbow. Explore attractions like Florida Theatre, TIAA Bank Field, and museums, while enjoying convenient transportation options.

American Beach

If you're spending some time in American Beach, American Beach and Spanish Quarter Village are top sights worth seeing.

Sawgrass

Visitors to Sawgrass like its beaches and riverfront, and Mickler Beach is a sight worth a stop.

Southside

If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

Top Isle of Palms Hotel Reviews

Frequently asked questions

What is Isle of Palms like?
Travelers are sure to enjoy a stay in Jacksonville Beach's Isle of Palms neighborhood.
What's a favorite place to stay in Isle of Palms?
Based on Expedia customer reviews, Residence Inn By Marriott Jacksonville - Mayo Clinic Area is the highest ranked property in Isle of Palms. This hotel offers free breakfast and an outdoor pool.
How many hotels can I expect to find in Isle of Palms?
Expedia has 40 hotels and other accommodations in Isle of Palms to choose from, making this an ideal home base for exploring the greater Jacksonville Beach area.
If I need to cancel my hotel reservation in Isle of Palms, will I receive a refund?
Yes, you'll find most hotel reservations are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you have a reservation that's non-refundable, it might still be possible to cancel it and receive a refund within 24 hours of booking. Add your dates and click on "Search", then use the "fully refundable" filter to get top deals in Isle of Palms.
Where can I learn more about changing or cancelling my trip to Isle of Palms?
For more information about changing or cancelling your trip to Isle of Palms, head over to our customer service page.
What is there to do in this Jacksonville Beach neighborhood?
A few places to visit in the area around Isle of Palms include Adventure Landing, Cradle Creek Preserve, and Jacksonville Beach Golf Club. While you're out sightseeing in Jacksonville Beach, be sure to visit other sights like Windsor Parke Golf Club or Players by the Sea.