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Mar 10 - Mar 11
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Mar 11 - Mar 12
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Mar 13 - Mar 15
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Mar 20 - Mar 22

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Our top choices for Isle of Palms South hotels

Exterior

Holiday Inn Express Jacksonville - Blount Island by IHG

Holiday Inn Express Jacksonville - Blount Island by IHG
2.5 star property
20.2 km from Isle of Palms South
8.8 out of 10, Excellent, (1,002 reviews)
"Room was clean and staff is always friendly. "
United States
Cary Jo
The price is ₩150,497
₩170,814 total
includes taxes & fees
Mar 16 - Mar 17
Holiday Inn Express Jacksonville - Blount Island by IHG
Sports facility

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
9.5 km from Isle of Palms South
9.2 out of 10, Wonderful, (1,007 reviews)
"very friendly staff!! i love staying here!!"
United States
Evani
The price is ₩168,202
₩190,910 total
includes taxes & fees
Apr 5 - Apr 6
Hyatt Place Jacksonville / St. Johns Town Center
Exterior

Hyatt Regency Jacksonville

Hyatt Regency Jacksonville
4.0 star property
22.1 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,540 reviews)
"The room was great with the river view, clean and the staff was great! "
United States
OLGA
The price is ₩224,309
₩257,137 total
includes taxes & fees
Apr 3 - Apr 4
Hyatt Regency Jacksonville
Balcony

Dune House Hotel and Spa

Dune House Hotel and Spa
4.5 star property
6.8 km from Isle of Palms South
8.8 out of 10, Excellent, (1,003 reviews)
"Great hotel!!…. Beautiful room overlooking the ocean!!!"
United States
David
The price is ₩294,049
₩396,786 total
includes taxes & fees
Mar 22 - Mar 23
Dune House Hotel and Spa
Double Room, 2 Queen Beds, Non Smoking | In-room dining

San Marco Inn East

San Marco Inn East
3.0 star property
19.5 km from Isle of Palms South
8.4 out of 10, Very Good, (1,397 reviews)
"Probably nicest motel I've stayed at for the price!"
United States
Nelson
San Marco Inn East
Free daily buffet breakfast

Hampton Inn & Suites Jacksonville South - Bartram Park

Hampton Inn & Suites Jacksonville South - Bartram Park
3.0 star property
18.4 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,010 reviews)
"Clean room, good breakfast, friendly and helpful staff. It was my second time staying there, and there's a reason I came back. I'd happily stay there again, too."
United States
Nicolas
The price is ₩168,896
₩191,696 total
includes taxes & fees
Mar 30 - Mar 31
Hampton Inn & Suites Jacksonville South - Bartram Park
Lobby

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
4.8 km from Isle of Palms South
9.0 out of 10, Wonderful, (3,767 reviews)
"Yes room was spotless and staff was amazing!"
United States
Martina
The price is ₩249,378
₩283,045 total
includes taxes & fees
Apr 5 - Apr 6
Margaritaville Jacksonville Beach
41-inch Smart TV with cable channels

Weekly Inn

Weekly Inn
2.0 star property
14.7 km from Isle of Palms South
7.6 out of 10, Good, (1,150 reviews)
"Room was clean no frills worth the money for a quick stay. "
United States
Deborah
Weekly Inn
Lobby

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.8 km from Isle of Palms South
9.2 out of 10, Wonderful, (1,013 reviews)
"Very friendly staff, good restaurants in hotel and in the complex "
United States
Richard
The price is ₩227,457
₩253,615 total
includes taxes & fees
Apr 5 - Apr 6
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
Lobby lounge

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
Isle of Palms, 2 km from Isle of Palms South
9.4 out of 10, Exceptional, (469 reviews)
"Clean room, amazing staff great location "
United States
Darlene
The price is ₩238,969
₩271,230 total
includes taxes & fees
Mar 20 - Mar 21
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Lobby sitting area

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
3.7 km from Isle of Palms South
8.8 out of 10, Excellent, (1,018 reviews)
"Staff was nice and room was clean "
United States
Charles
The price is ₩177,394
₩201,342 total
includes taxes & fees
Mar 22 - Mar 23
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Property amenity

TownePlace Suites by Marriott® Jacksonville Mayport

TownePlace Suites by Marriott® Jacksonville Mayport
3.0 star property
9.7 km from Isle of Palms South
9.8 out of 10, Exceptional, (86 reviews)
"New, clean room and nice breakfast."
United States
Gregory
The price is ₩184,433
₩209,332 total
includes taxes & fees
Apr 5 - Apr 6
TownePlace Suites by Marriott® Jacksonville Mayport
Reception

Midtown Lodge

Midtown Lodge
2.5 star property
18.9 km from Isle of Palms South
8.2 out of 10, Very Good, (609 reviews)
"Friendly staff good location"
United States
STEVE
Midtown Lodge
Terrace/patio

Home2 Suites By Hilton Jacksonville Downtown

Home2 Suites By Hilton Jacksonville Downtown
3.0 star property
24.2 km from Isle of Palms South
9.2 out of 10, Wonderful, (295 reviews)
"The room was very clean, the staff very friendly, everything was great! "
United States
Starla
The price is ₩186,321
₩211,474 total
includes taxes & fees
Mar 29 - Mar 30
Home2 Suites By Hilton Jacksonville Downtown
On the beach

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
4.6 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,002 reviews)
"Great location, breakfast was delicious "
United States
Paul
The price is ₩188,844
₩214,340 total
includes taxes & fees
Mar 22 - Mar 23
Best Western Oceanfront
Exterior

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
3.8 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,041 reviews)
"Clean room, good breakfast and location"
United States
Jesus
The price is ₩192,370
₩218,339 total
includes taxes & fees
Mar 22 - Mar 23
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Premium bedding, desk, blackout drapes, iron/ironing board

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin
3.0 star property
21.1 km from Isle of Palms South
7.4 out of 10, Good, (413 reviews)
"The room was amazing"
United States
Stephen
The price is ₩107,871
₩122,433 total
includes taxes & fees
Mar 29 - Mar 30
La Quinta Inn & Suites by Wyndham Jacksonville Mandarin
Room, 2 Queen Beds, Balcony, Oceanfront (Balcony) | Premium bedding, in-room safe, desk, laptop workspace

Courtyard by Marriott Jacksonville Beach Oceanfront

Courtyard by Marriott Jacksonville Beach Oceanfront
3.0 star property
5.2 km from Isle of Palms South
8.4 out of 10, Very Good, (1,000 reviews)
"very clean room,friendly staff"
United States
john
The price is ₩287,198
₩325,970 total
includes taxes & fees
Mar 22 - Mar 23
Courtyard by Marriott Jacksonville Beach Oceanfront
Serves lunch and dinner

Marriott Jacksonville Downtown

Marriott Jacksonville Downtown
4.0 star property
22.8 km from Isle of Palms South
8.4 out of 10, Very Good, (1,000 reviews)
"Hotel is very clean. Stsff at front desk was very friendly and helpfull."
United States
Sharon
The price is ₩297,276
₩337,408 total
includes taxes & fees
Apr 3 - Apr 4
Marriott Jacksonville Downtown
Standard Room, 1 King Bed, Non Smoking | Down comforters, minibar, iron/ironing board, WiFi

The Hotel Palms

The Hotel Palms
3.5 star property
6.6 km from Isle of Palms South
9.6 out of 10, Exceptional, (294 reviews)
"stayed here for an event and it was awesome"
United States
clayton
The price is ₩278,862
₩316,516 total
includes taxes & fees
Apr 6 - Apr 7
The Hotel Palms
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Isle of Palms South

Find the best Isle of Palms South areas and neighborhoods for the activities you enjoy most.
FernandinaBeach_AmericanBeach_553248621561735369_05

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Downtown Jacksonville which includes skyline, a city and a river or creek
Photo by Ryan Ketterman
Open Photo by Ryan Ketterman

Downtown Jacksonville

Historic core with major corporations, Downtown Jacksonville offers diverse culinary and nightlife experiences at The Elbow. Explore attractions like Florida Theatre, TIAA Bank Field, and museums, while enjoying convenient transportation options.

Ponte Vedra Beach.
Photo by Russell Hewatt
Open Photo by Russell Hewatt

Sawgrass

Visitors to Sawgrass like its beaches and riverfront, and Mickler Beach is a sight worth a stop.

American Pitbull Terrier

American Beach

If you're spending some time in American Beach, American Beach and Spanish Quarter Village are top sights worth seeing.

Jacksonville_StJohnsTownCenter_6127793_05

Southside

If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

Top Isle of Palms South Hotel Reviews

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

10/10 Excellent
"Yes and yes"
Kaige 1-night trip
Posted 2 hours ago
Margaritaville Jacksonville Beach

Frequently asked questions

What is Isle of Palms South like?
Travelers will be sure to find plenty to entertain them in Jacksonville Beach's Isle of Palms South neighborhood.
How many hotels will I be able to find in Isle of Palms South?
Expedia has 9 Isle of Palms South hotels and other accommodations, and one might make a good home base for venturing out into the greater Jacksonville Beach area.
If I need to cancel my hotel reservation in Isle of Palms South, will I receive a refund?
Yes, the majority of hotel room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then use the "fully refundable" filter to view top deals in Isle of Palms South.
Where can I learn more about changing or cancelling my trip to Isle of Palms South?
To find more details about changing or cancelling your trip to Isle of Palms South, go to https://www.expedia.com/service/.
What are the top things to see and do in Isle of Palms South?
Cradle Creek Preserve, Windsor Parke Golf Club, and Jacksonville Beach Golf Club are just a few of the places to visit in and around Isle of Palms South. Windsor Commons Shopping Center and Harbor City Municipal Golf Course are also worth a visit when you're out sightseeing in Jacksonville Beach.