A sunny street lined with historic buildings, a 'ONE WAY' sign, and a flagpole with flags.

Key West, Florida hotel rooms at the Wyndham Hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 18 - Aug 19
Tomorrow
Aug 19 - Aug 20
This weekend
Aug 21 - Aug 23
Next weekend
Aug 28 - Aug 30
Save an average of 15% on thousands of hotels when you're signed in

Top Key West Hotel Reviews

La Concha Key West, Autograph Collection

La Concha Key West, Autograph Collection

10/10 Excellent
"It was an excellent historic boutique hotel. Beautiful and comfortable room with a good bathroom…great location in the heart of Key West … very friendly staff"
Francisco 3-night trip
Posted 3 hours ago
La Concha Key West, Autograph Collection
Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

10/10 Excellent
"Super clean room! So many things to do- pool, beach, restaurants!! Staff was super awesome and friendly. We loved it!!!"
Olivia 3-night trip
Posted 3 hours ago
Southernmost Beach Resort and Guesthouses
Margaritaville Beach House Key West

Margaritaville Beach House Key West

8/10 Good
"Everything was nice but I didn't like"
Shalanda 3-night trip
Posted 5 hours ago
Margaritaville Beach House Key West
Pier House Resort & Spa

Pier House Resort & Spa

8/10 Good
"Room was ok only, AC had issues and location was difficult. There were upgraded rooms available but the charges didn’t make any sense, $50 a night for a room the same size but a slightly better location. Beach area was nice, location is great, Beach attendant couldn’t be bothered to help guests, Food servers never picked up after serving which left the birds to clean off the plates. You get the idea, great location not so great service."
Alan 1-night trip
Posted 5 hours ago
Pier House Resort & Spa
DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

10/10 Excellent
"No complaints."
Joey 3-night trip
Posted 6 hours ago
DoubleTree Resort by Hilton Grand Key - Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

8/10 Good
"The free breakfast every morning was filling. They also shuttle you to a designated area that is walking distance from lots of shops and activities. They also pick you up from the same designated spot as at scheduled times. Definitely save money on the UBERING."
Josh 5-night trip
Posted 7 hours ago
Hampton Inn Key West FL
The Perry Hotel & Marina Key West

The Perry Hotel & Marina Key West

10/10 Excellent
"We had a great stay, staff were very friendly and helpful. The only concern was that since it was “off” season for them the restaurants and bars closed early."
Anthony 4-night trip
Posted 8 hours ago
The Perry Hotel & Marina Key West
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

10/10 Excellent
"This resort is amazing. We have stayed here for the past 3 years and plan to go back again next year. The only thing that I would have a small complaint is there is no microwave in the rooms. We wasted alot of leftover food from restaurants because there was no way to heat it back up. After the first couple of meals we learned to eat appetizers or share an entree."
Nicole 7-night trip
Posted 9 hours ago
Blue Flamingo Resort Key West
Hilton Garden Inn Key West / The Keys Collection

Hilton Garden Inn Key West / The Keys Collection

10/10 Excellent
"Con gusto se puede ir a disfrutar"
Jose A 2-night trip
Posted 9 hours ago
Hilton Garden Inn Key West / The Keys Collection

Explore a world of travel with Expedia