The Best Hotels Closest to Knapp Medical Center in Weslaco for 2026

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Our top choices for Knapp Medical Center hotels

A modern kitchen with grey cabinets, stainless steel appliances, and a dining area with a glass table and chairs.

A modern living room with a brown leather sofa, a dining area with a table and chairs, and a kitchen with dark cabinets and a refrigerator.

A modern bedroom with a bed, nightstands, a dresser, a mirror, and a decorative wall piece.

A modern kitchen with stainless steel appliances, a dining table with chairs, and a potted plant.

1. Elegant Apartment 10 min to Mercedes Outlets

2.4 km from Knapp Medical Center

kraig

₩86,618

₩197,434 total

includes taxes & fees

Nov 3 - Nov 4

A hotel with a swimming pool, lounge chairs, and palm trees.

A lobby with a sofa, armchair, and a TV mounted on the wall.

A fitness room with a treadmill, exercise bike, and fan.

A kitchenette with a coffee machine, microwave, toaster, and various appliances.

2. Super 8 by Wyndham Weslaco

2 km from Knapp Medical Center

gerald

₩79,743

₩90,109 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with a bed, bedside table, and a small table with a chair.

A lobby with a reception desk, two patterned armchairs, a coffee table, a Christmas tree, and a door with an exit sign.

A hotel sign, a parking lot, and a building with a tiled roof.

A yellow building with a covered entrance and a garden in front.

3. Weslaco Inn Weslaco/Mercedes

1.4 km from Knapp Medical Center

Bartolo

₩79,037

₩104,457 total

includes taxes & fees

Nov 1 - Nov 2

A library with bookshelves, a globe, and a mural.

A parking lot with a clear sky, palm trees, and a building in the background.

A spacious kitchen with a dining area, a ceiling fan, and a view of the outside.

A hotel room with two beds, a desk, a chair, and a TV.

4. Vali Ho Motel By OYO Weslaco Mercedes

1 km from Knapp Medical Center

William

₩66,347

₩81,613 total

includes taxes & fees

Oct 20 - Oct 21

A restaurant interior with a seating area, tables, and a counter.

A long, narrow hotel hallway with a patterned carpet and doors on either side.

A modern interior with a reception desk, a black couch, and a dining area with chairs and tables.

A modern interior with a counter, seating area, and a TV screen.

5. Express Inn

2 km from Knapp Medical Center

Kassandra

₩81,579

₩97,338 total

includes taxes & fees

Oct 4 - Oct 5

A modern kitchen with a dining area, featuring stainless steel appliances, grey cabinets, and a black dining table with chairs.

A white door with a 'D' marking, a doormat with 'Welcome' written on it, a blue window with blinds, and a wall-mounted light fixture.

A bedroom with two beds, a nightstand, a wall-mounted tree decoration, and two white doors.

A parking area with a row of white buildings, each with a garage door and a number on the side.

6. Apartment With 3 Bedrooms 40 Minutes From South Padre

2.4 km from Knapp Medical Center

Julia

₩86,618

₩197,434 total

includes taxes & fees

Oct 13 - Oct 14

A modern living room with a flat-screen TV, two light blue armchairs, a brown sofa, and a glass coffee table.

A modern building with a covered walkway and a parking lot.

A modern bedroom with a four-poster bed, a ceiling fan, a bedside table with a lamp, a bench, and a chair.

A modern kitchen with a marble countertop, four red velvet chairs with gold legs, and stainless steel appliances.

7. Beautiful Apartment 9 min to Mercedes Outlets

2.4 km from Knapp Medical Center

Jorge

₩80,951

₩203,878 total

includes taxes & fees

Oct 6 - Oct 7

A modern hotel with a prominent "HOME 2" sign, a covered entrance, and a well-lit facade.

A hotel room with a bed, a desk with a TV, a kitchenette, a bathroom, and a living area with a sofa and lamp.

A rectangular swimming pool with clear blue water, surrounded by a tiled deck. There are chairs and tables under a wooden pergola, and a fence with a gate in the background.

8. Home2 Suites By Hilton San Juan

16.6 km from Knapp Medical Center

Jessica

₩114,318

₩126,893 total

includes taxes & fees

Oct 11 - Oct 12

A hotel room with two beds, a desk, a chair, and a large window.

A Hampton Inn hotel with a covered entrance, multiple floors, and a parking lot.

A hotel reception area with a coffee station, a sign reading "HAPPY DREAMS START HERE", and a view of the lobby.

A conference room with a patterned carpet, recessed ceiling lights, and a row of framed pictures on the back wall.

9. Hampton Inn Weslaco

4.2 km from Knapp Medical Center

Jorge

₩132,687

₩149,936 total

includes taxes & fees

Oct 26 - Oct 27

A breakfast buffet area with various food items and a sign that reads "HAPPY BREAKFAST STARTS HERE".

A pool area with lounge chairs, a pool, and palm trees.

A hotel reception desk with a 'Welcome to the Lone Star' sign, a 'Hilton Honors' badge, and a 'Suite Shop' sign.

A modern Hampton Inn hotel with a prominent entrance, large windows, and a well-lit facade.

10. Hampton Inn Weslaco

4.1 km from Knapp Medical Center

Isaac

₩130,790

₩147,793 total

includes taxes & fees

Nov 2 - Nov 3

A modern hotel lobby with a bar area, seating, and a television.

A modern living area with a sofa, chairs, a coffee table, and a decorative vase.

A spacious living area with a kitchen, bar area, and seating.

A hotel room with a large bed, a desk with a chair, a flat-screen TV mounted on the wall, and a window with blue curtains.

11. La Quinta Inn & Suites by Wyndham Mercedes Outlet Mall

9.8 km from Knapp Medical Center

Sandra

₩119,424

₩134,959 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a bed, a desk, a chair, a table, a ceiling fan, a TV, and a door.

A small kitchenette with a microwave, a sink, and a cabinet. There is a framed picture on the wall and a tiled backsplash.

A bathroom with a bathtub, shower, and toilet.

A compact kitchenette with a microwave, coffee maker, and a small refrigerator.

12. Texas Inn Donna

6.9 km from Knapp Medical Center

Martha

₩87,444

₩98,810 total

includes taxes & fees

Oct 14 - Oct 15

A hotel dining area with wooden tables and chairs, a central bar, and a kitchen in the background.

A Comfort Inn & Suites with a pool area featuring lounge chairs and a stone facade.

A hotel reception area with a digital check-in kiosk, a sign for Comfort Inn & Suites, and a Christmas decoration on the ceiling.

A multi-story Comfort Inn & Suites with a covered entrance, palm trees, and a parking lot.

13. Comfort Inn & Suites Donna near I-2

8.7 km from Knapp Medical Center

maria

₩104,815

₩118,441 total

includes taxes & fees

Nov 1 - Nov 2

A modern building with a red and beige facade, large windows, and a parking lot with several cars.

A swimming pool with a metal ladder, a lifeguard chair, and a red building in the background.

A hotel reception area with a glass door entrance, a reception desk, and a sign promoting a mobile app.

A Taco Palenque restaurant with a parking lot and a building with a 'NOW OPEN' sign.

14. Motel 6 Weslaco, TX

3.3 km from Knapp Medical Center

Joel

₩84,428

₩95,405 total

includes taxes & fees

Nov 1 - Nov 2

A modern lobby with a reception desk, blue seating area, and a kitchen in the background.

A modern kitchen with a central island, dark cabinetry, and a purple accent wall.

A hotel room with a blue sofa, a wooden coffee table, a patterned carpet, and framed artwork on the walls.

A hotel room with two beds, a large window with curtains, a desk with a flat-screen TV, and a heater.

15. Best Western Town Center Inn

3.8 km from Knapp Medical Center

Benjamin

₩119,129

₩134,616 total

includes taxes & fees

Nov 1 - Nov 2

A spacious indoor area with multiple tables and chairs, large windows, and a ceiling fan.

A brick building with a brown awning labeled 'Victoria Restaurant.' There are palm trees and a parking lot in front.

A spacious room with a wooden floor, a large chandelier, and a modern ceiling design.

A hotel room with a bed, a chair, a nightstand with a lamp, a vanity with a mirror and lights, and a framed picture on the wall.

16. Victoria Palms Inn & Suites

5.3 km from Knapp Medical Center

Misael

₩76,902

₩86,899 total

includes taxes & fees

Oct 29 - Oct 30

A Rodeway Inn with a covered entrance, palm trees, and a clear blue sky.

A rectangular swimming pool with a metal ladder on one side, surrounded by a concrete deck. There are two small bushes and a white wall with warning signs.

A hotel room with two beds, each with patterned bedspreads, a nightstand with a lamp, and two framed pictures on the wall.

A hotel room with a large bed, two bedside tables with lamps, and two framed pictures on the wall.

17. Rodeway Inn San Juan

18.5 km from Knapp Medical Center

Paul

₩62,661

₩69,553 total

includes taxes & fees

Nov 2 - Nov 3

A breakfast bar with various food items and a beverage dispenser.

A hotel room with a bed, a nightstand, a lamp, a sofa, a ceiling fan, and a door.

A reception area with a tiled floor, a reception desk, a waiting area with chairs, and a door leading to the kitchen.

A reception desk with a stone facade, a glass partition, and a sign for Quality Inn & Suites.

18. Quality Inn & Suites at The Outlets Mercedes/Weslaco

8.7 km from Knapp Medical Center

Martin

₩89,602

₩101,250 total

includes taxes & fees

Oct 25 - Oct 26

An indoor swimming pool with a red border, a ladder, and depth markers.

An outdoor swimming pool with lounge chairs and a red safety sign indicating a depth of 3 feet.

A hotel room with a large bathtub, a bed, a desk, and a television.

A Texas Inn building with a large entrance, palm trees, and a clear blue sky.

19. Texas Inn Alamo

15 km from Knapp Medical Center

Jose

₩84,428

₩95,405 total

includes taxes & fees

Oct 4 - Oct 5

A bathroom with a granite countertop, a sink, and a mirror. There are towels hanging on a rack, a shower curtain rod, and a trash bin.

A parking lot with multiple cars and a swimming pool.

A building with a sign reading "TEXAS INN" and a garden with red roses in front.

A reception area with a glass door entrance, a reception desk, a ceiling fan, and a Christmas tree.

20. Texas Inn La Feria

15.5 km from Knapp Medical Center

Alexander

₩95,950

₩110,343 total

includes taxes & fees

Oct 11 - Oct 12

View all properties

Compare popular hotels close to Knapp Medical Center

Property	Property class	Guest rating
Elegant Apartment 10 min to Mercedes Outlets	9.8 Exceptional 7 reviews	View
Super 8 by Wyndham Weslaco	8.8 Excellent 1,000 reviews	View
Weslaco Inn Weslaco/Mercedes	8.4 Very good 658 reviews	View
Vali Ho Motel By OYO Weslaco Mercedes	8.4 Very good 238 reviews	View
Express Inn	6.4 409 reviews	View

Top Knapp Medical Center Hotel Reviews

Wyndham Garden McAllen at La Plaza Mall

10/10 Excellent

"Location is perfect"

Rodeway Inn San Juan

8/10 Good

"Nice place to stay , breakfast not so good but I can score them 3star"

Holiday Inn Express Hotel & Suites Pharr by IHG

8/10 Good

"Hhhhhù"

Victoria Palms Inn & Suites

10/10 Excellent

"Loved loved loved the pool area and customer service. No issies. Will definitely revisit. Thank you Fernando for making our check in a smooth one. Much appreciated 👏"

Super 8 by Wyndham Weslaco

10/10 Excellent

"Very clean room, very good staff"

MainStay Suites Edinburg South

8/10 Good

"Breakfast, clean room, great staff"

Hampton Inn Weslaco

8/10 Good

"The room had a bad smell of men’s cologne that was very strong as I walked in. The a/c was amazing. The breakfast was horrible. Non edible eggs"

Weslaco Inn Weslaco/Mercedes

10/10 Excellent

"It’s always quiet and close by for some dancing."

Quality Inn & Suites at The Outlets Mercedes/Weslaco

10/10 Excellent

"Clean room and great parking lot"

Frequently asked questions

What's the area like around Knapp Medical Center?

Knapp Medical Center is located in a budget-friendly area of Weslaco that travelers like for its cathedral. If you're looking for a convenient place to stay, check out the 21 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Knapp Medical Center?

Weslaco Inn Weslaco/Mercedes is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an outdoor pool. It's located just a short 0.8 mi (1.4 km) from Knapp Medical Center. Other good options within 5 miles include Super 8 by Wyndham Weslaco and Holiday Inn Express Hotel & Suites Weslaco by IHG.

How many hotels will I be able to find close to Knapp Medical Center?

Expedia has 21 hotels and other accommodations within a mile from Knapp Medical Center.

If I need to cancel the hotel reservation for my stay near Knapp Medical Center, will I receive a refund?

Yes! Most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within 24 hours of booking. Add dates, click "Search", then use the "fully refundable" filter to view the best options available near Knapp Medical Center.

Where can I learn more about changing or cancelling my trip in the area near Knapp Medical Center?

To access more information about updating your stay near Knapp Medical Center or cancelling it, go to https://www.expedia.com/service/.

Find hotels near Knapp Medical Center, Weslaco from ₩69,553

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Our top choices for Knapp Medical Center hotels

1. Elegant Apartment 10 min to Mercedes Outlets

2. Super 8 by Wyndham Weslaco

3. Weslaco Inn Weslaco/Mercedes

4. Vali Ho Motel By OYO Weslaco Mercedes

5. Express Inn

6. Apartment With 3 Bedrooms 40 Minutes From South Padre

7. Beautiful Apartment 9 min to Mercedes Outlets

8. Home2 Suites By Hilton San Juan

9. Hampton Inn Weslaco

10. Hampton Inn Weslaco

11. La Quinta Inn & Suites by Wyndham Mercedes Outlet Mall

12. Texas Inn Donna

13. Comfort Inn & Suites Donna near I-2

14. Motel 6 Weslaco, TX

15. Best Western Town Center Inn

16. Victoria Palms Inn & Suites

17. Rodeway Inn San Juan

18. Quality Inn & Suites at The Outlets Mercedes/Weslaco

19. Texas Inn Alamo

20. Texas Inn La Feria

Compare popular hotels close to Knapp Medical Center

Top Knapp Medical Center Hotel Reviews

Wyndham Garden McAllen at La Plaza Mall

Rodeway Inn San Juan

Holiday Inn Express Hotel & Suites Pharr by IHG

Victoria Palms Inn & Suites

Super 8 by Wyndham Weslaco

MainStay Suites Edinburg South

Hampton Inn Weslaco

Weslaco Inn Weslaco/Mercedes

Quality Inn & Suites at The Outlets Mercedes/Weslaco

Frequently asked questions