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Find Business Hotels in Lower Keys, FL

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Check availability on Lower Keys Business Hotels

Tonight
Dec 22 - Dec 23
Tomorrow
Dec 23 - Dec 24
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Our top choices for Lower Keys business-friendly hotels

Bar (on property)
Fairfield Inn & Suites by Marriott Marathon Florida Keys

Fairfield Inn & Suites by Marriott Marathon Florida Keys

Fairfield Inn & Suites by Marriott Marathon Florida Keys
2.5 star property
Marathon
9.2 out of 10, Wonderful, (1049)
"Great staff, clean room, good breakfast "
United States
Kelly
The price is ₩323,570
₩364,024 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Fairfield Inn & Suites by Marriott Marathon Florida Keys
On the beach, beach cabanas, sun loungers
Courtyard by Marriott Faro Blanco Resort, Marathon Florida Keys

Courtyard by Marriott Faro Blanco Resort, Marathon Florida Keys

Courtyard by Marriott Faro Blanco Resort, Marathon Florida Keys
3.0 star property
Marathon
9.0 out of 10, Wonderful, (1004)
"Food great. Grounds kept prestine"
United States
Donald
The price is ₩353,120
₩455,429 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Courtyard by Marriott Faro Blanco Resort, Marathon Florida Keys
4 outdoor pools, pool umbrellas, sun loungers
Parrot Key Hotel & Villas

Parrot Key Hotel & Villas

Parrot Key Hotel & Villas
4.0 star property
Northside Resort
9.0 out of 10, Wonderful, (1204)
"Great place to stay 👌 👍 "
United States
james
The price is ₩287,593
₩408,320 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Parrot Key Hotel & Villas
3 outdoor pools, sun loungers
Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort
4.0 star property
Marathon
8.8 out of 10, Excellent, (1005)
"Great resort with lots of fun things to do. Really enjoyed our stay there. Would highly recommend it."
United Kingdom
Jaskaran
The price is ₩471,615
₩627,283 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Tranquility Bay Beachfront Hotel and Resort
Restaurant
Hampton Inn Marathon - Florida Keys

Hampton Inn Marathon - Florida Keys

Hampton Inn Marathon - Florida Keys
2.5 star property
Marathon
9.0 out of 10, Wonderful, (1003)
"Stay is excellent, highly recommended for families "
United States
Srikanth
The price is ₩331,962
₩373,457 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hampton Inn Marathon - Florida Keys
Outdoor pool, sun loungers
Skipjack Resort & Marina

Skipjack Resort & Marina

Skipjack Resort & Marina
3.0 star property
Marathon
8.6 out of 10, Excellent, (1218)
"Beautiful location clean rooms friendly staff "
United States
Tiffany
Skipjack Resort & Marina
2 bars/lounges, poolside bar
Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton
4.0 star property
Marathon
8.8 out of 10, Excellent, (1271)
"Very nice resort. All the staff was friendly and helpful. The pool bar was great and the bartender was friendly. Our favorite place to stay in Marathon."
United States
William
The price is ₩422,828
₩531,280 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton
Front of property
Siesta Motel

Siesta Motel

Siesta Motel
2.0 star property
Marathon
7.4 out of 10, Good, (693)
"Excellent motel for visiting nearby marina. A/C did fine even at 92F outdoors. "
United States
Maggie
The price is ₩269,273
₩302,930 total
includes taxes & fees
Dec 23 - Dec 24
Siesta Motel
Couples treatment rooms, facials, massages
Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses
4.0 star property
Old Town Key West
8.8 out of 10, Excellent, (2936)
"Great Stay!"
United States
mathew
The price is ₩414,377
₩574,222 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Southernmost Beach Resort and Guesthouses
Outdoor pool, open 7:00 AM to 11:00 PM, cabanas (surcharge)
DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West
4.0 star property
Key West
8.2 out of 10, Very Good, (1007)
"Nice property, comfortable stay - cookies and staff are great!"
United States
David
The price is ₩353,416
₩447,458 total
includes taxes & fees
Jan 4 - Jan 5, 2026
DoubleTree Resort by Hilton Grand Key - Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Lower Keys Hotel Reviews

Parmer's Resort

Parmer's Resort

10/10 Excellent
"Room was clean and comfortable."
Barbara K 1-night trip
Posted 12 days ago
Parmer's Resort

Frequently asked questions

How much do business-friendly hotels in Lower Keys cost?
Business-friendly hotels in Lower Keys range between ₩302,930 and ₩627,283 per night. This means you can reserve a stay with perks like workspaces and conference rooms at a price that fits your budget. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Why book your business-friendly hotel in Lower Keys with Expedia?
Here at Expedia, our business is to help you land an ideal stay at the right price. From 5-star corporate-friendly escapes to affordable hotels filled with conveniences, you'll have your next work trip organized in a few easy clicks.
How can I find cheap business-friendly hotels in Lower Keys?
When work takes you to Lower Keys, our "business friendly" filter will help you find the perfect hotel. From dependable WiFi to meeting rooms and workspaces, they have the amenities you need to do your job. You can also refine your search by your preferred star rating and budget to see the most affordable properties.
What is there to do in Lower Keys near my business-friendly hotel?
Lower Keys has so much to do and see, it can be difficult to decide where to begin. If you're spending a few nights in Summerland Key, Florida Keys Beaches is a favorite here.