A modern building with a curved glass facade, surrounded by a well-maintained lawn and several trees.

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Our top choices for Mcleod Regional Medical Center hotels

A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.
A modern bar area with a long counter, bar stools, and a variety of bottles and glasses.
A multi-story hotel with a modern facade, featuring a prominent 'Hyatt Place' sign on the right.
A modern bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.

1. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
0.7 km from Mcleod Regional Medical Center
United States
Ivette
₩134,100
₩150,192 total
includes taxes & fees
Nov 3 - Nov 4
Hyatt Place Florence Downtown
A restaurant with brick walls, framed awards, and a bar area.
A spacious kitchen with a dining area, a living room with a fireplace, and a cozy seating arrangement.
An outdoor patio area with a brick wall, a covered seating area with string lights, and potted plants.
A spacious living room with a wooden floor, a ceiling fan, and a dining area with a wooden table and chairs.

2. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
0.8 km from Mcleod Regional Medical Center
United States
Ankh
₩185,836
₩208,137 total
includes taxes & fees
Oct 30 - Oct 31
Hotel Florence, Tapestry Collection by Hilton
A sign for the Rodeway Inn.

3. Rodeway Inn Florence Downtown

Rodeway Inn Florence Downtown
1.2 km from Mcleod Regional Medical Center
United States
F
₩56,993
₩65,750 total
includes taxes & fees
Nov 15 - Nov 16
Rodeway Inn Florence Downtown
A modern kitchen with stainless steel appliances, a gray sofa, and a ceiling fan.
A modern living room with a brick wall, a grey sofa, a wooden coffee table, and a view through large windows.
A modern kitchen with a built-in dishwasher, a large island with a sink, pendant lights, and a ceiling fan.
A modern kitchen with grey cabinets, stainless steel appliances, and bar stools.

4. The Urban Flats

The Urban Flats
0.8 km from Mcleod Regional Medical Center
₩383,526
₩630,701 total
includes taxes & fees
Oct 21 - Oct 22
The Urban Flats
A hotel lobby with a reception desk, seating area, and a television screen.
A spacious dining area with multiple tables and chairs, large windows, and a flat-screen TV mounted on the wall.
A hotel room with a bed, a sofa, an ottoman, and a lamp.
A Comfort Inn & Suites hotel with a covered entrance, brick facade, and multiple windows.

5. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
7 km from Mcleod Regional Medical Center
United States
Mila
₩135,642
₩151,917 total
includes taxes & fees
Nov 8 - Nov 9
Comfort Inn & Suites Florence Center Area
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.
A Hampton Inn & Suites with a large sign, brick facade, and a parking lot.
A hotel room with two beds, a desk, a TV, and a window with patterned curtains.
A lobby with a fireplace, seating area, and a television.

6. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
7.2 km from Mcleod Regional Medical Center
United States
Ryan
₩152,740
₩171,070 total
includes taxes & fees
Nov 1 - Nov 2
Hampton Inn & Suites Florence Center
A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.
A conference room with round tables, chairs, and a carpeted floor.
A hotel room with a bed, a desk, a TV, a refrigerator, and a painting on the wall.
An outdoor kitchen area with a grill, a pool, and a covered seating area.

7. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
8.1 km from Mcleod Regional Medical Center
United States
Tishia
₩181,035
₩202,760 total
includes taxes & fees
Nov 1 - Nov 2
Staybridge Suites Florence - Civic Center by IHG
A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.
A large, two-story building with a central entrance flanked by columns, labeled "DIR FRANK B. LEE NURSING BUILDING."
A hotel lobby with a reception desk, seating area, and artwork on the walls.
An outdoor patio area with brick walls, a fire pit, and outdoor seating.

8. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
9.1 km from Mcleod Regional Medical Center
United States
Christopher
₩170,307
₩204,022 total
includes taxes & fees
Nov 1 - Nov 2
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.
A modern living room with a grey sofa, a flat-screen TV, geometric wall art, and a bookshelf with decorative items.
A modern hotel with a 'Park Inn by Radisson' sign, featuring a covered entrance, multiple windows, and a parking lot.

9. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
5.5 km from Mcleod Regional Medical Center
United States
Juan
₩119,751
₩134,121 total
includes taxes & fees
Nov 8 - Nov 9
Park Inn by Radisson Florence, SC
A spacious lobby with a checkered floor, a reception desk, and a chandelier.
A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.
A hotel room with two beds, a desk with a computer, a chair, and a bathroom with a mirror.
A two-story building with a brick facade, a flat roof, and a covered entrance area.

10. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
5.5 km from Mcleod Regional Medical Center
United States
Alanda
₩86,735
₩97,142 total
includes taxes & fees
Oct 18 - Oct 19
Howard Johnson by Wyndham Florence
A hotel entrance with a stone facade, glass doors, and a number '501' above.
An indoor swimming pool with a tiled floor, a pool ladder, and lounge chairs.
A modern living room with a stone fireplace, a blue sofa, a brown leather chair, and a round coffee table.
A corner market with shelves stocked with snacks and beverages, and two large refrigerators.

11. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
6.9 km from Mcleod Regional Medical Center
United States
Alma
₩158,439
₩177,450 total
includes taxes & fees
Nov 8 - Nov 9
Fairfield Inn & Suites by Marriott Florence I-20
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.
A reception area with a wooden desk, a map on the wall, and a sign welcoming visitors to Florence, SC.
A modern hotel room with a kitchenette, a grey sofa, a dining area, and a sign that reads "A Great Day Starts With Breakfast."
A modern lounge area with a sofa, armchairs, and small tables.

12. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
7 km from Mcleod Regional Medical Center
United States
Crystal
₩147,041
₩164,686 total
includes taxes & fees
Nov 1 - Nov 2
TownePlace Suites by Marriott Florence
An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.
A snack kiosk with a variety of snacks and beverages, a sign for a 24/7 market, and a sign for local items.
A modern hotel restaurant with a breakfast bar, seating area, and a view of the city.
A modern hotel with a prominent 'TRU by Hilton' sign, a well-lit entrance, and a landscaped front yard.

13. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
5.9 km from Mcleod Regional Medical Center
United States
Tiffany
₩147,041
₩172,665 total
includes taxes & fees
Oct 22 - Oct 23
Tru by Hilton Florence I-95
A spacious lobby with a high ceiling, a central seating area with armchairs and a coffee table, a flat-screen TV, and a dining area with tables and chairs.
A modern hotel lobby with a fireplace, seating area, and a reception desk.
A modern hotel lobby with a central seating area, a large abstract painting, and a patterned carpet.
A spacious lobby with a large seating area, a flat-screen TV, and a fireplace.

14. Residence Inn Marriott Florence

Residence Inn Marriott Florence
7.2 km from Mcleod Regional Medical Center
United States
Teri
₩143,755
₩161,004 total
includes taxes & fees
Nov 8 - Nov 9
Residence Inn Marriott Florence
A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.
A hotel room with two beds, a desk with a chair, a television, and a window with curtains.
A hotel with a modern design, featuring a prominent sign for the 'Country Inn & Suites by Radisson.'
A modern cafeteria with long wooden tables, green chairs, and yellow accents.

15. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
5.5 km from Mcleod Regional Medical Center
United States
Tienia
₩112,845
₩131,685 total
includes taxes & fees
Nov 8 - Nov 9
Spark by Hilton Florence North I-95, SC
A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.
An indoor swimming pool with clear water, surrounded by a checkered wall pattern, and equipped with multiple seating areas and a lifeguard station.
A Hampton Inn & Suites hotel with a well-lit entrance, multiple floors, and a parking area.
A lobby with leather sofas, a coffee table, potted plants, and a reception desk.

16. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
5.7 km from Mcleod Regional Medical Center
United States
Ashokraju
₩164,138
₩183,835 total
includes taxes & fees
Oct 22 - Oct 23
Hampton Inn & Suites Florence-North-I-95
A spacious lobby with a reception desk, seating area, and large windows.
A Hilton Garden Inn with a large, multi-story building, a covered entrance, and a parking lot.
A spacious lobby with a large fireplace, comfortable seating, and potted plants.
An indoor swimming pool with clear poolside areas, a lifeguard station, and a view of the outside.

17. Hilton Garden Inn Florence

Hilton Garden Inn Florence
7.2 km from Mcleod Regional Medical Center
United States
Derrick
₩158,439
₩177,452 total
includes taxes & fees
Nov 8 - Nov 9
Hilton Garden Inn Florence
A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.
A snack and beverage display area with shelves stocked with various brands and a refrigerator with beverages.
A coffee station with two coffee machines and a display of coffee pods and cups.
A reception area with a modern design, featuring a reception desk, a digital display, and a sign for Holiday Inn Express & Suites.

18. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
8 km from Mcleod Regional Medical Center
United States
Leigh
₩152,874
₩171,220 total
includes taxes & fees
Nov 1 - Nov 2
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
A hotel room with a desk, chair, bed, and a yellow sofa.
A hotel with a green roof, a sign reading 'Quality Inn & Suites by Choice Hotels,' and a landscaped front yard with small trees and shrubs.
A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.
A swimming pool with lounge chairs and a building with balconies.

19. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
7.5 km from Mcleod Regional Medical Center
United States
Sharhonda
₩119,483
₩133,820 total
includes taxes & fees
Nov 1 - Nov 2
Quality Inn & Suites Florence Civic Center
Terrace/patio
A hotel room with a bed, a desk, a green sofa, and a painting on the wall.
A hotel room with a desk, a green armchair, a small purple ottoman, a bed with a white headboard, and a large window.
A spacious lobby with a reception desk, seating area with patterned chairs, and a coffee station.

20. Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC
7.7 km from Mcleod Regional Medical Center
United States
saleh
₩147,839
₩173,567 total
includes taxes & fees
Nov 4 - Nov 5
Home2 Suites by Hilton Florence, SC
View all properties

Top Mcleod Regional Medical Center Hotel Reviews

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

10/10 Excellent
"Amazing"
Danya 2-night trip
Posted 5 hours ago
Quality Inn & Suites Florence Civic Center
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

8/10 Good
"Staff was helpful, Rooms were definitely an upgrade from the Days Inns I had been staying in!! Continental breakfast was okay, would have liked to have bananas and some yogurt!!"
Bobbie 1-night trip
Posted 1 day ago
Howard Johnson by Wyndham Florence
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

10/10 Excellent
"Room was very clean and modern. Price was good. Good breakfast."
Ronald 1-night trip
Posted 2 days ago
Comfort Inn & Suites Florence Center Area
Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

8/10 Good
"The staff were great!! Parking was close by and easy. The restaurant bar was a great stop. If you want a refrigerator in your room you need to ask prior to arrival."
Wendy 1-night trip
Posted 6 days ago
Hotel Florence, Tapestry Collection by Hilton
Comfort Suites Florence I-95

Comfort Suites Florence I-95

10/10 Excellent
"Everything was excellent- the staff, the rooms, the parking, you name it. Very satisfied"
Mary 1-night trip
Posted 8 days ago
Comfort Suites Florence I-95

Frequently asked questions

What's the area like around Mcleod Regional Medical Center?
Mcleod Regional Medical Center is located in a welcoming area of Florence known for its array of dining options. If you're looking for a convenient place to stay, check out the 18 hotels and other accommodations you'll find within a mile.
What's the best hotel to stay near Mcleod Regional Medical Center?
Hyatt Place Florence Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a restaurant. It's located just a short 0.4 mi (0.7 km) from Mcleod Regional Medical Center. Other good options within a short distance include Hotel Florence, Tapestry Collection by Hilton and The Urban Flats.
How many hotels will I find near Mcleod Regional Medical Center?
Expedia has 18 hotels and other accommodations within a mile from Mcleod Regional Medical Center.
If I need to cancel the hotel reservation for my stay near Mcleod Regional Medical Center, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to view the best deals near Mcleod Regional Medical Center.
Where can I learn more about changing or cancelling my trip in the area near Mcleod Regional Medical Center?
For more information about updating your stay near Mcleod Regional Medical Center or cancelling it, click here.
What can I see and do near Mcleod Regional Medical Center?
You can enjoy live performances at FMU Performing Arts Center and Florence Little Theatre. You might spend a leisurely day outdoors at Florence Veterans Park and Greenwood Baseball Park and Playground. Create some family memories at Sky Zone Trampoline Park and Tilt Studio.