Medical Center Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ₩234,741 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Medical Center

Find the best Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center
United States of America featuring a bay or harbor, landscape views and a city

Downtown Detroit

6 out of top 10 points of interest in this area
4/5(1,947 area reviews)

Central business district meets residential area, Downtown Detroit boasts historic architecture, skyscrapers, and parks. Explore attractions like Campus Martius Park, Fox Theatre, and Detroit Riverwalk, with convenient transport options nearby.

Find hotels in Downtown Detroit

Medical Center Hotel Deals

Hollywood Casino at Greektown

Hollywood Casino at Greektown

4 out of 5
1200 Saint Antoine St Detroit MI
The price is ₩226,043 per night from Dec 22 to Dec 23
₩226,043
₩302,974 total
Dec 22 - Dec 23
includes taxes & fees
8.6/10 Excellent! (4,921 reviews)
It was Awesome. Beautiful area but under construction. When the pedestrian esplanades are finished it is going to be great!

Reviewed on Dec 19, 2025

Hollywood Casino at Greektown
MotorCity Casino Hotel

MotorCity Casino Hotel

4.5 out of 5
2901 Grand River Ave Detroit MI
Fully refundableReserve now, pay when you stay
8.6/10 Excellent! (4,383 reviews)
Everything was great

Reviewed on Dec 20, 2025

Get rates
MotorCity Casino Hotel
The Siren Hotel, an Ash Hotel

The Siren Hotel, an Ash Hotel

4 out of 5
1509 Broadway St. Detroit MI
The price is ₩223,396 per night from Dec 22 to Dec 23
₩223,396
₩252,438 total
Dec 22 - Dec 23
includes taxes & fees
8.8/10 Excellent! (1,772 reviews)
The mattress is on the floor. What are we doing? Also no chair to sit in a $240 room ia wild. Stools don't count. But the coffee was good and shower stellar.

Reviewed on Dec 20, 2025

The Siren Hotel, an Ash Hotel
See all 1,810 properties in Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Medical Center vacation package cost?
Maybe less than you might think — from only , as a matter of fact! By combining hotels, flights and car rentals into your own tailor-made travel package, your trip to Medical Center is just clicks away.
How do I get a cheap travel package to Medical Center?
Bundle your bookings with Expedia to save big on your next adventure. With over 550 partner airlines and 1,000,000 hotels worldwide, your Medical Center vacation package can be tailored exactly to suit your travel style. With all that extra money, why not include one or more exciting tours and activities? It's an easy way to unlock even more savings. That dream vacation to Medical Center is much closer than you thought!
Where should I stay in Medical Center?
Take the leg work out of sightseeing by staying someplace near Medical Center's fantastic attractions. Henry Ford Museum and Ford Field are two of the best in the area.
How far in advance should I book my Medical Center vacation?
While prices change from time to time, we generally suggest booking your flight as early as possible. Most international airfares can be found on Expedia up to 12 months in advance. If you're booking last minute, you might still get lucky. Cheap tickets to Medical Center sometimes emerge just weeks before departure.
What does an Expedia Medical Center travel package include?
Hotels, flights and a cool set of wheels for all your fun road trip adventures. Simply mix and match your favorite bundle and get access to incredible deals. Once you've made your booking, add on a couple of experiences and tours and watch your savings grow. When it comes to creating your Medical Center break, you're the one in control!
What should I know before booking a Medical Center travel package?
So many places to explore, so many things to see and do. With a travel package, you'll be able to cross more of them off your list. Bundle your flights, rental cars and hotels and make big savings.
Can I choose my airline with a Medical Center Expedia vacation package?
Yes, you sure can. We have more than 550 partner airlines all over the world, so choose the carrier that's a good fit for your budget and travel needs.
If I'm not able to travel, can I cancel my Medical Center vacation package?
Whether it's your hotel or flight, you can cancel and rebook it. Locked in your Medical Center vacation package in the last 24 hours? You may be able to make any changes for free. For older bookings, you may incur a fee from your airline, hotel or car rental company. For further information, check out our Customer Service Portal. We'll help you each step of the way.

Discover the most popular places to visit in Medical Center

An amazing collection of cars on display at the Henry Ford Museum.

Henry Ford Museum

See the limousine in which JFK was assassinated, historical buildings and vehicles, and exhibits that document the evolution and impact of technology.

Henry Ford Museum
GM Renaissance Center featuring a high rise building and interior views

GM Renaissance Center

A distinctive point on the Detroit skyline, this collection of skyscrapers is the global headquarters of General Motors and a popular entertainment destination.

GM Renaissance Center
This is an amazing place to see a show if you're in Detroit!

Fox Theatre

Enjoy a show at Fox Theatre, a theater with a story to tell in Detroit. Discover the acclaimed art scene and casinos in this vibrant area.

Fox Theatre
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.