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Dec 26 - Dec 27
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Dec 27 - Dec 28
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Dec 26 - Dec 28
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Our top choices for Murex Lakes hotels

Outdoor pool, open 8:00 AM to 10:00 PM, cabanas (surcharge)
The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
15.7 km from Murex Lakes
9.0 out of 10, Wonderful, (1000)
"Excellent stay over Thanksgiving holiday!"
United States
Nicole
The price is ₩291,826
₩383,322 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The Westin Cape Coral Resort At Marina Village
View from room
Matlacha on Shoreview

Matlacha on Shoreview

Matlacha on Shoreview
2.0 star property
23.2 km from Murex Lakes
9.6 out of 10, Exceptional, (215)
"Place was great. Nice and neat perfect for what i needed."
United States
Michael
The price is ₩94,147
₩201,873 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Matlacha on Shoreview
Terrace/patio
Dolphin Key Resort

Dolphin Key Resort

Dolphin Key Resort
3.0 star property
21 km from Murex Lakes
8.8 out of 10, Excellent, (1213)
"Nice rooms, great having the bar onsite"
United States
Lee
The price is ₩115,873
₩129,198 total
includes taxes & fees
Dec 29 - Dec 30
Dolphin Key Resort
Balcony view
OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL
2.5 star property
23.2 km from Murex Lakes
5.8 out of 10, (1003)
"Beautiful place "
United States
Blaine
The price is ₩104,389
₩126,497 total
includes taxes & fees
Dec 28 - Dec 29
OYO Waterfront Hotel - Cape Coral/Fort Myers, FL
Exterior
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
2.5 star property
20.2 km from Murex Lakes
8.6 out of 10, Excellent, (1001)
"The rooms were clean, staff were very friendly and accommodating."
United States
Sandra
The price is ₩176,432
₩196,722 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
Free buffet breakfast
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
21.2 km from Murex Lakes
9.4 out of 10, Exceptional, (1087)
"Is great place to stay."
United States
Anastassia
The price is ₩190,612
₩212,532 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Exterior
Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort
2.5 star property
8.1 km from Murex Lakes
9.6 out of 10, Exceptional, (144)
"great boutique hotel in an amazing area on Pine Island Fl. Great restaurants and bars walkable and great fishing. "
United States
Pat
The price is ₩289,843
₩371,479 total
includes taxes & fees
Dec 30 - Dec 31
Off the Charts Inn & Out Island Resort
Exercise/lap pool
Hyatt Vacation Club at Coconut Cove, Bonita Springs

Hyatt Vacation Club at Coconut Cove, Bonita Springs

Hyatt Vacation Club at Coconut Cove, Bonita Springs
4.0 star property
26.3 km from Murex Lakes
9.2 out of 10, Wonderful, (740)
"Room great clean, staff great.loved pool"
United States
Dennis
The price is ₩304,228
₩395,562 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hyatt Vacation Club at Coconut Cove, Bonita Springs
Property amenity
TownePlace Suites by Marriott Fort Myers Estero

TownePlace Suites by Marriott Fort Myers Estero

TownePlace Suites by Marriott Fort Myers Estero
3.5 star property
29.6 km from Murex Lakes
9.4 out of 10, Exceptional, (467)
"Clean room and very nice staff"
United States
Nancy
The price is ₩229,601
₩256,004 total
includes taxes & fees
Jan 1 - Jan 2, 2026
TownePlace Suites by Marriott Fort Myers Estero
Outdoor pool, a heated pool, sun loungers
Resort Harbour Properties

Resort Harbour Properties

Resort Harbour Properties
3.5 star property
10.8 km from Murex Lakes
9.6 out of 10, Exceptional, (364)
"10/10 would stay there again"
United States
Kristie
Resort Harbour Properties
Deluxe Studio Suite | Terrace/patio
White Orchid Apartments

White Orchid Apartments

White Orchid Apartments
2.0 star property
15.3 km from Murex Lakes
8.0 out of 10, Very Good, (49)
"Place was nice and private. "
United States
Dawn
The price is ₩99,940
₩158,268 total
includes taxes & fees
Dec 27 - Dec 28
White Orchid Apartments
Outdoor pool
Sanibel Island Beach Resort

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 5.3 km from Murex Lakes
9.2 out of 10, Wonderful, (1487)
"Excellent value with a great location and a solid staff!"
United States
David
The price is ₩374,004
₩453,115 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Sanibel Island Beach Resort
Basic Studio | Private kitchen | Dining tables
Summerwind Studios

Summerwind Studios

Summerwind Studios
2.0 star property
17.5 km from Murex Lakes
8.0 out of 10, Very Good, (11)
"Very clean and roomy. Quiet neighborhood. Loves the shower; so relaxing. Only complaint is that we could have used some drinking glasses. I would stay here again. "
United States
Micki
The price is ₩103,970
₩162,619 total
includes taxes & fees
Dec 27 - Dec 28
Summerwind Studios
Economy Studio (Turtle) | Private kitchen
TriLuxe Inn & Studios

TriLuxe Inn & Studios

TriLuxe Inn & Studios
2.0 star property
17.4 km from Murex Lakes
8.2 out of 10, Very Good, (17)
"Everything was great, will definitely be coming back"
United States
Ruben
The price is ₩102,526
₩161,009 total
includes taxes & fees
Dec 28 - Dec 29
TriLuxe Inn & Studios
4 outdoor pools
Hyatt Regency Coconut Point Resort & Spa

Hyatt Regency Coconut Point Resort & Spa

Hyatt Regency Coconut Point Resort & Spa
4.5 star property
26.6 km from Murex Lakes
9.0 out of 10, Wonderful, (1000)
"This is a fabulous hotel in every way. The staff are outstanding especially Ursula who went out of her way to make sure we had what we needed. The hotel and it’s restaurants are wonderful. It is situated in the middle of beautiful groves with its on private island. Shopping is close by."
United States
Debra
The price is ₩709,721
₩864,020 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Hyatt Regency Coconut Point Resort & Spa
Outdoor pool, open 7:00 AM to 6:00 PM, pool umbrellas, sun loungers
Hyatt Place Fort Myers Estero

Hyatt Place Fort Myers Estero

Hyatt Place Fort Myers Estero
3.5 star property
29.1 km from Murex Lakes
8.8 out of 10, Excellent, (1001)
"Great staff!"
United States
Marlene
The price is ₩257,037
₩286,597 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hyatt Place Fort Myers Estero
On the beach, white sand, kayaking, motor boating
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
10.9 km from Murex Lakes
8.4 out of 10, Very Good, (1004)
"This was thr best place that we have ever stayed at. "
United States
Matthew
The price is ₩460,646
₩549,721 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Marriott Sanibel Harbour Resort & Spa
Exterior
Sanibel Inn

Sanibel Inn

Sanibel Inn
3.0 star property
East End, 6.3 km from Murex Lakes
9.0 out of 10, Wonderful, (1000)
"Just beautiful! Couldn’t ask for a better stay in Sanibel "
United States
Jennifer Rebecca
The price is ₩510,041
₩652,421 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Sanibel Inn
Exterior
Latitude 26 Waterfront Boutique Resort - Bonita Springs

Latitude 26 Waterfront Boutique Resort - Bonita Springs

Latitude 26 Waterfront Boutique Resort - Bonita Springs
3.0 star property
29.2 km from Murex Lakes
8.8 out of 10, Excellent, (708)
"Super location charming place, a total hidden gem!"
United States
Jay
Latitude 26 Waterfront Boutique Resort - Bonita Springs
Luxury Suite, Sea View | Beach/ocean view
Island Inn

Island Inn

Island Inn
3.5 star property
West End, 0.8 km from Murex Lakes
9.4 out of 10, Exceptional, (1123)
"Really nice, updated, and clean room with a screened waterfront balcony in a perfect place on the island (far enough away from the big resorts to be in a quieter area, but close enough to the center area of the island to be convenient). "
United States
Chris
The price is ₩375,138
₩418,280 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Island Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Murex Lakes

Find the best Murex Lakes areas and neighborhoods for the activities you enjoy most.
Fort Myers featuring a sandy beach
Photo by Sanibel Captiva Chamber of Commerce/Milissa Sprecher Photography
Open Photo by Sanibel Captiva Chamber of Commerce/Milissa Sprecher Photography

West End

While visiting West End, you might make a stop by sights like J. N. Ding Darling National Wildlife Refuge and Bowman's Beach.

Sanibel Historical Museum and Village showing heritage elements

Mid Island

While visiting Mid Island, you might make a stop by sights like Periwinkle Way and Sanibel Island Southern Beach.

J. N. Ding Darling National Wildlife Refuge which includes marine life and dangerous animals

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

Periwinkle Way featuring cycling as well as an individual femail

Beachview Country Club Estates

If you're spending some time in Beachview Country Club Estates, Periwinkle Way and Sanibel Island Golf Club are top sights worth seeing.

Sanctuary

While Sanctuary might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Blind Pass Beach and Turner Beach.

Top Murex Lakes Hotel Reviews

Sanibel Island Beach Resort

Sanibel Island Beach Resort

10/10 Excellent
"Lovely resort, not too big and not too small. Right on the beach, very nice property. Convenient location to other restaurants, stores, and bike rental. Staff were all super friendly. Restaurant had excellent brekkie and lunch - didn't try dinner. Rooms modern and clean. Would definitely stay again!"
John 3-night trip
Posted 3 days ago
Sanibel Island Beach Resort

Frequently asked questions

What's it like in Murex Lakes?
You'll be sure to have fun visiting Sanibel's Murex Lakes neighborhood.
How many hotels are there in Murex Lakes?
If you're searching for places to stay in Sanibel, choose from one of Expedia's 17 hotels and other accommodations in Murex Lakes.
If I need to cancel my hotel reservation in Murex Lakes, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to view the top deals on offer in Murex Lakes.
Where can I learn more about changing or cancelling my trip to Murex Lakes?
To find more details about picking new dates or cancelling your trip to Murex Lakes, go to https://www.expedia.com/service/.
What is there to do around this Sanibel neighborhood?
Sanibel Captiva Conservation Foundation, Bailey - Matthews Shell Museum, and Sanibel Island Southern Beach are just a few of the places to visit in and around Murex Lakes. When you're sightseeing in Sanibel, Sanibel Historical Museum and Village and Sanibel Historical Village and Museum are also worth a stop.