
Northeast Missouri Vacations
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Where to stay in Northeast Missouri

Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

St. Charles Historic District
Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.
Find the Best Northeast Missouri Vacation Packages
Northeast Missouri Hotel Deals

Clayton Plaza Hotel & Extended Stay
"Room was great and clean, pool was nice, food was EXCELLENT!"
Reviewed on Aug 7, 2026

Hollywood Casino & Hotel St. Louis

Renaissance St. Louis Airport Hotel
Stay near popular Northeast Missouri attractions
Busch Stadium
St. Louis Zoo

Enterprise Center

Dome at America’s Center

Forest Park

City Museum

