A pier extending into calm waters with a small boat docked at the end.

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Sep 22 - Sep 23
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Sep 23 - Sep 24
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Sep 25 - Sep 27
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Oct 2 - Oct 4

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Our top choices for Panacea hotels

A pink door with a window, set in a corrugated metal exterior with wooden trim.
A kitchen with a wooden countertop, a built-in sink, and a trash can.
A kitchen with white cabinets, a stainless steel refrigerator, a microwave, a stove, and a sink. There are wooden shelves above the counter and a window with a view.
A bedroom with a bed, a bench, a wooden wardrobe, and a wall with starfish and a framed picture.

1. The Panacea Motel

The Panacea Motel
Panacea
United States
Dashawn
₩163,667
₩182,488 total
includes taxes & fees
Oct 1 - Oct 2
The Panacea Motel
A spacious lobby with leather sofas, a coffee table, and a large window with arched frames.
A boat docked at a pier with passengers on board.
A spacious lobby with high ceilings, ornate ceiling decorations, and large windows.
A spacious dining area with multiple tables and chairs, large windows, and hanging chandeliers.

2. The Lodge at Wakulla Springs

The Lodge at Wakulla Springs
Crawfordville
United States
Joy
₩122,607
₩136,715 total
includes taxes & fees
Sep 29 - Sep 30
The Lodge at Wakulla Springs
A spacious indoor area with tiled flooring, multiple tables and chairs, a stone fireplace, and a glass door entrance.
A hotel with a red facade, a covered entrance, and palm trees.
A hotel room with a bed, a desk, a chair, a small table with a vase, a trash bin, and a wooden door.

3. Wildwood Inn

Wildwood Inn
Crawfordville
United States
Kizzy
₩160,753
₩184,734 total
includes taxes & fees
Oct 18 - Oct 19
Wildwood Inn
A fountain with a dolphin statue in a courtyard, surrounded by buildings with arched windows and a pool with blue mosaic tiles.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A hotel with a covered patio, outdoor seating, and a central pathway leading to the entrance.
A hotel lobby with a coffee bar, seating area, and a clock on the wall.

4. Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites
Crawfordville
United States
James
₩154,446
₩172,207 total
includes taxes & fees
Oct 11 - Oct 12
Best Western Wakulla Inn & Suites
A bar area with a long counter, stools, and a variety of bottles and glasses.
A swimming pool with lounge chairs, palm trees, and a clear blue sky.
A resort with multiple tennis courts, a swimming pool, and a golf course.
A living room with a sofa set, a television, and a ceiling fan.

5. St James Bay Golf & Pickleball Resort

St James Bay Golf & Pickleball Resort
Carrabelle
United States
shane
₩144,792
₩210,902 total
includes taxes & fees
Sep 23 - Sep 24
St James Bay Golf & Pickleball Resort
A hotel room with two beds, a nightstand, a lamp, and a bathroom visible through an open door.
A motel with a row of rooms, a staircase, and a parking area.
A motel with a single-story structure, a covered parking area, and a palm tree in front.
A hotel room with a large bed, two bedside tables, a desk with a chair, and a lamp.

6. Franklin Inn

Franklin Inn
Carrabelle
United States
Nathan
₩129,189
₩142,754 total
includes taxes & fees
Sep 27 - Sep 28
Franklin Inn
A covered patio with a table and chairs, a wooden ceiling fan, and a view of the surrounding greenery.
A cozy living room with a sofa, a small table, and a ceiling fan.
A yellow door with a window, a potted plant, a white wall-mounted light fixture, and a staircase with yellow curtains.
The Carrabelle Hotel with a white exterior, multiple balconies, and surrounded by tropical vegetation.

7. The Old Carrabelle Hotel

The Old Carrabelle Hotel
Carrabelle
United States
Christy
₩144,656
₩159,845 total
includes taxes & fees
Oct 1 - Oct 2
The Old Carrabelle Hotel
A marina with boats docked, a small building, and a clear sky.
A spacious room with a pool table, a round dining table with chairs, and large windows offering a view of a body of water.
A marina with multiple docks and boats, connected by walkways, and surrounded by greenery and buildings.
A spacious room with a pool table, a billiards table, and a dining area with chairs and a table.

8. The Moorings Hotel and Marina

The Moorings Hotel and Marina
Carrabelle
United States
Tina
₩189,586
₩209,493 total
includes taxes & fees
Oct 1 - Oct 2
The Moorings Hotel and Marina
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Stay near popular Panacea attractions

Alligator Point Beach

8.8/10 (10 reviews)
Escape to this pristine stretch of old coastal Florida with white sands and shallow, clear waters. Spot dolphins and sea turtles while enjoying the serenity of an undeveloped shoreline.
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Bald Point State Park

8.6/10 (20 reviews)
Where Ochlockonee Bay meets Apalachee Bay, this coastal park showcases diverse ecosystems from beaches to pine flatwoods. Spot migrating raptors and monarch butterflies while hiking through pristine natural habitats.
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Mashes Sand Beach

8.8/10 (3 reviews)
Mashes Sands Beach offers serene shallow waters and expansive sandbars perfect for peaceful exploration. Wade through the tea-colored Gulf waters while spotting hermit crabs and enjoying spectacular sunset views.
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Wilson Beach

Wilson Beach offers a serene Gulf Coast escape with pristine shores and gentle waves far from tourist crowds. Bring supplies and enjoy peaceful beachcombing along this unspoiled natural sanctuary.
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Public Beach Access

Mashes Sands Beach features tranquil white-sand shores and shallow waters ideal for families. Wade in the gentle surf, cast a fishing line, or enjoy a peaceful picnic away from tourist crowds.
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Silver Lake

Swim in crystal-clear waters along a pristine 250-foot white sand beach surrounded by longleaf pines. The mile-long interpretive trail offers peaceful wildlife encounters with bald eagles and turtles.
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Panacea Springs

Once a popular health resort, these historic mineral springs were believed to possess healing properties in the early 1900s. Explore the remnants of spa structures while imagining the therapeutic rituals of a bygone era.
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Gulf Specimen Public Aquarum

Take the kids to visit the sea life you'll find at Gulf Specimen Public Aquarum during your trip to Panacea. Stroll along the beaches in this relaxing area, or seek out the fishing spots.
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Learn more about Panacea

Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails.

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A sunset over a calm body of water with silhouettes of birds flying and a distant tree line.

Top Panacea Hotel Reviews

The Panacea Motel

The Panacea Motel

10/10 Excellent
"Other than everything close perfect spot"
Dashawn 1-night trip
Posted 4 days ago
The Panacea Motel

More cheap stays in Panacea

Franklin Inn

Franklin Inn

1589 US-98 Carrabelle FL
₩129,189
₩142,754 total
Sep 27 - Sep 28
includes taxes & fees
Franklin Inn
The Old Carrabelle Hotel

The Old Carrabelle Hotel

201 Tallahassee St Carrabelle FL
₩144,656
₩159,845 total
Oct 1 - Oct 2
includes taxes & fees
The Old Carrabelle Hotel
Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites

3292 Coastal Hwy 98 Crawfordville FL
₩154,446
₩172,207 total
Oct 11 - Oct 12
includes taxes & fees
Best Western Wakulla Inn & Suites
The Panacea Motel

The Panacea Motel

1545 Coastal Hwy Panacea FL
₩163,667
₩182,488 total
Oct 1 - Oct 2
includes taxes & fees
9/10 Wonderful! (193 reviews)
The Panacea Motel
The Moorings Hotel and Marina

The Moorings Hotel and Marina

1000 Hwy 98 Carrabelle FL
₩189,586
₩209,493 total
Oct 1 - Oct 2
includes taxes & fees
8.6/10 Excellent! (54 reviews)
The Moorings Hotel and Marina
Cozy Waterfront 'island House' on Live Oak Island!

Cozy Waterfront 'island House' on Live Oak Island!

Crawfordville FL
Get ratesCozy Waterfront 'island House' on Live Oak Island!

Frequently asked questions

If I need to cancel my hotel reservation in Panacea, will I receive a refund?
Yes! Most hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Panacea.
Where can I learn more about changing or cancelling my trip to Panacea?
For more details about changing or cancelling your trip to Panacea, click here.
What's the best pet-friendly place to stay in Panacea?
The Panacea Motel is a top pet-friendly option for your stay. See more pet-friendly hotel accommodations in Panacea.
What's the best hotel for staying near Tallahassee Regional Airport (TLH)?
Tallahassee Sun & Moon is one of the top choices for your stay and is a popular property, featuring free WiFi and free parking. It's located 3.5 mi (5.7 km) from Tallahassee Regional Airport. Other options close to the airport include Hampton Inn & Suites Tallahassee Capitol-University and Governors Inn.
What's it like to stay in Panacea?
Nature enthusiasts will enjoy exploring Panacea, and many visitors are sure to appreciate the beaches and seafood restaurants. The relaxing and tucked away setting also entices those visiting the city. In Panacea, there are 229 hotels and other accommodations to choose from. Find out more about Panacea.
What are the top places to visit in Panacea?
Natural beauty is on display at Mashes Sand Beach, Alligator Point Beach, and Bald Point State Park. Dolphin watching is a great activity, and Bayside Marina is one place to visit. A couple of additional sights to add to your agenda are Wilson Beach and Public Beach Access. Check out what more to see and do in Expedia's Panacea guide.
What's the seasonal weather like in Panacea?
The hottest months are usually July and August with an average temp of 81°F, while the coldest months are January and February with an average of 58°F. The rainiest months in Panacea are August, July, June, and September, with each month seeing an average of 8 inches of rainfall.

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