Find hotels near Penn Presbyterian Medical Center, Philadelphia from ₩153,944

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Our top choices for Penn Presbyterian Medical Center hotels

Lobby
The Gables B&B Philadelphia

The Gables B&B Philadelphia

The Gables B&B Philadelphia
4.0 star property
1.7 km from Penn Presbyterian Medical Center
9.8 out of 10, Exceptional, (453)
"I really loved the historical feeling of this beautiful property, and even though I was staying for work, it was a great place to spend a few evenings! Loved it!"
United States
Cailyn
The price is ₩325,048
₩375,430 total
includes taxes & fees
Jan 15 - Jan 16, 2026
The Gables B&B Philadelphia
Property entrance
The Study at University City

The Study at University City

The Study at University City
4.0 star property
University City, 1 km from Penn Presbyterian Medical Center
9.4 out of 10, Exceptional, (1002)
"Friendly staff, clean and stylish hotel"
United States
Sara
The price is ₩294,534
₩342,740 total
includes taxes & fees
Dec 24 - Dec 25
The Study at University City
Indoor pool, sun loungers
Four Seasons Hotel Philadelphia at Comcast Center

Four Seasons Hotel Philadelphia at Comcast Center

Four Seasons Hotel Philadelphia at Comcast Center
5.0 star property
Center City West, 2.5 km from Penn Presbyterian Medical Center
9.8 out of 10, Exceptional, (279)
"View was amazing "
United States
Adam
The price is ₩1,406,067
₩1,636,262 total
includes taxes & fees
Dec 28 - Dec 29
Four Seasons Hotel Philadelphia at Comcast Center
Lobby
The Inn at Penn, A Hilton Hotel

The Inn at Penn, A Hilton Hotel

The Inn at Penn, A Hilton Hotel
4.0 star property
University City, 0.6 km from Penn Presbyterian Medical Center
9.2 out of 10, Wonderful, (1011)
"The room was indeed spotless. The valet were excellent and we enjoyed our stay."
United States
Larry
The price is ₩192,972
₩224,562 total
includes taxes & fees
Jan 1 - Jan 2, 2026
The Inn at Penn, A Hilton Hotel
Premium bedding, down comforters, individually decorated
The DWIGHT D Hotel

The DWIGHT D Hotel

The DWIGHT D Hotel
5.0 star property
Rittenhouse Square, 2.9 km from Penn Presbyterian Medical Center
9.8 out of 10, Exceptional, (385)
"Friendly and helpfull owners."
United States
Frank
The price is ₩540,226
₩623,968 total
includes taxes & fees
Jan 5 - Jan 6, 2026
The DWIGHT D Hotel
Exterior detail
The Rittenhouse Philadelphia

The Rittenhouse Philadelphia

The Rittenhouse Philadelphia
5.0 star property
Rittenhouse Square, 2.4 km from Penn Presbyterian Medical Center
9.6 out of 10, Exceptional, (938)
"Nice room and staffs are helpful."
Canada
Kin Kwan
The price is ₩582,722
₩738,292 total
includes taxes & fees
Dec 30 - Dec 31
The Rittenhouse Philadelphia
Full breakfast for a fee on weekdays
Fitler Club

Fitler Club

Fitler Club
4.0 star property
Center City West, 1.8 km from Penn Presbyterian Medical Center
9.4 out of 10, Exceptional, (277)
"Fun hotel in excellent location "
United States
Diane
Fitler Club
Restaurant
The Maj Hotel

The Maj Hotel

The Maj Hotel
3.0 star property
2.1 km from Penn Presbyterian Medical Center
9.4 out of 10, Exceptional, (418)
"Very clean rooms and attentive staff. The location , close to Barnes foundation and the Art Museum was very important for me."
United States
Eugeni
The Maj Hotel
Exterior
ROOST Midtown

ROOST Midtown

ROOST Midtown
4.0 star property
Center City West, 3 km from Penn Presbyterian Medical Center
9.6 out of 10, Exceptional, (385)
"Super convenient to office at Liberty place. Very spacious apartment that was nearly brand new. "
United States
Jessica
The price is ₩225,119
₩260,019 total
includes taxes & fees
Jan 5 - Jan 6, 2026
ROOST Midtown
Exterior
AKA University City

AKA University City

AKA University City
4.0 star property
University City, 1.6 km from Penn Presbyterian Medical Center
9.2 out of 10, Wonderful, (710)
"great views of Philly!"
United States
Sara
The price is ₩391,535
₩498,609 total
includes taxes & fees
Jan 5 - Jan 6, 2026
AKA University City
Exterior
La Reserve Bed & Breakfast

La Reserve Bed & Breakfast

La Reserve Bed & Breakfast
3.5 star property
Rittenhouse Square, 2.7 km from Penn Presbyterian Medical Center
9.4 out of 10, Exceptional, (443)
"Great stay!"
United States
Colton
La Reserve Bed & Breakfast
Reception
4211 Suites

4211 Suites

4211 Suites
4.5 star property
0.7 km from Penn Presbyterian Medical Center
9.0 out of 10, Wonderful, (511)
"Room was clean and roomy, staff was excellent! "
United States
Joseph
The price is ₩196,828
₩229,049 total
includes taxes & fees
Jan 1 - Jan 2, 2026
4211 Suites
Bar (on property)
Element Philadelphia Downtown

Element Philadelphia Downtown

Element Philadelphia Downtown
4.0 star property
Center City West, 3 km from Penn Presbyterian Medical Center
9.2 out of 10, Wonderful, (1341)
"Room spotless, staff are lovely and breakfast buffet and serve yourself espresso machine —perfect. "
United States
Maureen
The price is ₩199,461
₩232,112 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Element Philadelphia Downtown
Exterior
Hyatt Centric Center City Philadelphia

Hyatt Centric Center City Philadelphia

Hyatt Centric Center City Philadelphia
4.0 star property
Rittenhouse Square, 2.9 km from Penn Presbyterian Medical Center
9.2 out of 10, Wonderful, (1545)
"We had a great stay! Staff was friendly andvery helpful."
United States
Anna L
The price is ₩234,921
₩273,379 total
includes taxes & fees
Jan 21 - Jan 22, 2026
Hyatt Centric Center City Philadelphia
3 restaurants, breakfast, lunch, dinner served; Mexican cuisine
Motto by Hilton Philadelphia Rittenhouse Square

Motto by Hilton Philadelphia Rittenhouse Square

Motto by Hilton Philadelphia Rittenhouse Square
3.5 star property
Center City West, 2.5 km from Penn Presbyterian Medical Center
9.0 out of 10, Wonderful, (1901)
"Love the stay. Would definitely stay again. "
United States
Songi
The price is ₩132,289
₩153,944 total
includes taxes & fees
Dec 25 - Dec 26
Motto by Hilton Philadelphia Rittenhouse Square
Front of property
The Franklin on Rittenhouse, A Boutique Hotel

The Franklin on Rittenhouse, A Boutique Hotel

The Franklin on Rittenhouse, A Boutique Hotel
4.0 star property
Rittenhouse Square, 2.7 km from Penn Presbyterian Medical Center
9.2 out of 10, Wonderful, (1002)
"Staff, amenities, great room"
United States
Phyllis
The price is ₩325,023
₩424,969 total
includes taxes & fees
Dec 24 - Dec 25
The Franklin on Rittenhouse, A Boutique Hotel
View from property
The Notary Hotel, Philadelphia, Autograph Collection by Marriott

The Notary Hotel, Philadelphia, Autograph Collection by Marriott

The Notary Hotel, Philadelphia, Autograph Collection by Marriott
4.0 star property
Center City West, 3.2 km from Penn Presbyterian Medical Center
9.2 out of 10, Wonderful, (1004)
"My family and I enjoyed our stay staff was great "
United States
John
The price is ₩265,081
₩360,158 total
includes taxes & fees
Dec 30 - Dec 31
The Notary Hotel, Philadelphia, Autograph Collection by Marriott
Exterior
Club Quarters Hotel Rittenhouse Square, Philadelphia

Club Quarters Hotel Rittenhouse Square, Philadelphia

Club Quarters Hotel Rittenhouse Square, Philadelphia
4.0 star property
Center City West, 2.8 km from Penn Presbyterian Medical Center
9.0 out of 10, Wonderful, (4257)
"Nice staff and accommodation"
United States
JINKY
The price is ₩171,536
₩199,615 total
includes taxes & fees
Dec 24 - Dec 25
Club Quarters Hotel Rittenhouse Square, Philadelphia
Exterior
Sofitel Philadelphia at Rittenhouse Square

Sofitel Philadelphia at Rittenhouse Square

Sofitel Philadelphia at Rittenhouse Square
4.5 star property
Center City West, 2.7 km from Penn Presbyterian Medical Center
9.0 out of 10, Wonderful, (2224)
"Loved our stay"
United States
Jacob
The price is ₩251,321
₩340,599 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Sofitel Philadelphia at Rittenhouse Square
Bar (on property)
AKA Rittenhouse Square

AKA Rittenhouse Square

AKA Rittenhouse Square
4.0 star property
Center City West, 2.6 km from Penn Presbyterian Medical Center
9.2 out of 10, Wonderful, (504)
"Staff, amenities, room was beautiful!"
United States
Maria
AKA Rittenhouse Square
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Penn Presbyterian Medical Center Hotel Reviews

Motto by Hilton Philadelphia Rittenhouse Square

Motto by Hilton Philadelphia Rittenhouse Square

10/10 Excellent
"Restaurants on premises."
Patricia 1-night trip
Posted 9 hours ago
Motto by Hilton Philadelphia Rittenhouse Square

Hotels near other Penn Presbyterian Medical Center attractions

uCity Square

You can find out about the history of Philadelphia when you stop by uCity Square. While you're here, you can savor the top-notch restaurants.
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Philadanco

You can enjoy some culture when you stop by Philadanco in Philadelphia. While you're here, you can savor the top-notch restaurants.
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Frequently asked questions

What's the area like around Penn Presbyterian Medical Center?
Penn Presbyterian Medical Center is located in Philadelphia. This welcoming area is known for its array of dining options. If you're looking for a convenient place to stay, check out the 150 hotels and other accommodations you'll find within a mile.
What's the best hotel to stay close to Penn Presbyterian Medical Center?
Adjacent to Penn Presbyterian Medical Center, Kasa The Niche University City Philadelphia is one of the top choices for your stay based on our traveler data, and this guesthouse offers free WiFi and LCD TVs. Other good options close by include 4211 Suites and The Inn at Penn, A Hilton Hotel.
How many hotels will I be able to find close to Penn Presbyterian Medical Center?
Expedia has 150 hotels and other accommodations within a mile from Penn Presbyterian Medical Center.
If I need to cancel the hotel reservation for my stay near Penn Presbyterian Medical Center, will I receive a refund?
Yes! The majority of room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to get the best deals near Penn Presbyterian Medical Center.
Where can I learn more about changing or cancelling my trip in the area near Penn Presbyterian Medical Center?
For additional details about updating your stay near Penn Presbyterian Medical Center or cancelling it, click here.
What can I see and do near Penn Presbyterian Medical Center?
Penn Museum, Philadelphia Museum of Art, and The Mütter Museum feature captivating exhibits. Sights like Franklin Field, Rocky Steps, and Eastern State Penitentiary are must-sees while exploring the area. You can catch a show at Academy of Music, Kimmel Center for the Performing Arts, and Miller Theater.
How can I get to Penn Presbyterian Medical Center?
With so many choices for transportation, seeing the area around Penn Presbyterian Medical Center is easy. You can walk to nearby metro stations including Penn Medicine Station, 33rd St Station, and 37th St Station. If you'd like to explore more of the area, hop aboard a train from Philadelphia University City Station, 30th St Station, or Philadelphia, PA (ZFV-30th Street Rail Station).