Photo by Mike McClain

Find hotels in Puxico, MO from ₩61,735

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 24 - Aug 25
Tomorrow
Aug 25 - Aug 26
Next weekend
Aug 29 - Aug 31
In two weeks
Sep 5 - Sep 7

Filter by

Guest rating
Guest rating
Star rating

Compare 53 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Our top choices for Puxico hotels

Holiday Inn Poplar Bluff by IHG
Breakfast, lunch, dinner served; Italian cuisine

Holiday Inn Poplar Bluff by IHG

3.0 star property
8.8 out of 10, Excellent, (671)
"Very clean and comfortable property close to dining options. Would definitely stay again "
The price is ₩139,742
₩157,874 total
includes taxes & fees
Aug 28 - Aug 29
Holiday Inn Poplar Bluff by IHG
Fairfield Inn & Suites by Marriott Poplar Bluff
Lobby lounge

Fairfield Inn & Suites by Marriott Poplar Bluff

2.5 star property
9.4 out of 10, Exceptional, (795)
"Hotel was very clean and the staff was friendly! I would stay again. "
The price is ₩136,974
₩154,746 total
includes taxes & fees
Sep 4 - Sep 5
Fairfield Inn & Suites by Marriott Poplar Bluff
Dexter Inn
Front of property - evening/night

Dexter Inn

2.5 star property
6.8 out of 10, (312)
"The bed was so comfortable and the pool was clean."
The price is ₩89,933
₩100,985 total
includes taxes & fees
Sep 7 - Sep 8
Dexter Inn
Super 8 by Wyndham Poplar Bluff Missouri
In-room safe, desk, free WiFi, bed sheets

Super 8 by Wyndham Poplar Bluff Missouri

2.0 star property
6.6 out of 10, (595)
"It was very nice, the staff was excellent, and the weather was great. "
The price is ₩82,337
₩93,021 total
includes taxes & fees
Sep 10 - Sep 11
Super 8 by Wyndham Poplar Bluff Missouri
Hampton Inn Poplar Bluff
Terrace/patio

Hampton Inn Poplar Bluff

2.5 star property
9.4 out of 10, Exceptional, (752)
"Excellent property, great location. "
The price is ₩134,069
₩150,124 total
includes taxes & fees
Sep 7 - Sep 8
Hampton Inn Poplar Bluff
Drury Inn & Suites Poplar Bluff
Lobby

Drury Inn & Suites Poplar Bluff

3.0 star property
9.2 out of 10, Wonderful, (898)
"Clean property with very friendly staff. "
The price is ₩130,043
₩146,895 total
includes taxes & fees
Aug 31 - Sep 1
Drury Inn & Suites Poplar Bluff
Econo Lodge Dexter
Desk, iron/ironing board, free WiFi, bed sheets

Econo Lodge Dexter

2.0 star property
6.8 out of 10, (242)
"Rough parking lot, sparse lobby, ok for one night on a trip, not a vacation spot"
The price is ₩76,429
₩85,821 total
includes taxes & fees
Sep 22 - Sep 23
Econo Lodge Dexter
Comfort Inn Poplar Bluff North
Lobby

Comfort Inn Poplar Bluff North

2.5 star property
7.8 out of 10, Good, (379)
"Everything about my stay "
The price is ₩121,880
₩137,695 total
includes taxes & fees
Sep 7 - Sep 8
Comfort Inn Poplar Bluff North
Travelodge by Wyndham Dexter
Breakfast, lunch, dinner served; American cuisine

Travelodge by Wyndham Dexter

2.0 star property
7.4 out of 10, Good, (366)
"A nice property just off the beaten path. "
The price is ₩139,465
₩156,608 total
includes taxes & fees
Aug 25 - Aug 26
Travelodge by Wyndham Dexter
Motel 6 Poplar Bluff, MO
Lobby

Motel 6 Poplar Bluff, MO

2.0 star property
7.8 out of 10, Good, (1003)
"Staff is excellent here. I stay here frequently in my travels and it is just fine for $70 a night. "
The price is ₩109,303
₩115,294 total
includes taxes & fees
Aug 25 - Aug 26
Motel 6 Poplar Bluff, MO
OYO Hickory House Inn
Room, 2 Queen Beds, Non Smoking | 1 bedroom, desk, iron/ironing board, free WiFi

OYO Hickory House Inn

2.5 star property
5.4 out of 10, (122)
"It was affordable and clean"
The price is ₩61,735
₩78,324 total
includes taxes & fees
Sep 23 - Sep 24
OYO Hickory House Inn
EC Reed's Mercantile and Hotel
Deluxe Double Room | 1 bedroom, premium bedding, individually decorated

EC Reed's Mercantile and Hotel

3.0 star property
9.6 out of 10, Exceptional, (77)
"Great, clean room and the restaurant attached was delicious- best breakfast! "
The price is ₩145,467
₩158,340 total
includes taxes & fees
Aug 25 - Aug 26
EC Reed's Mercantile and Hotel
Lake Wappapello
Front of property

Lake Wappapello

2.0 star property
The price is ₩190,934
₩201,388 total
includes taxes & fees
Aug 25 - Aug 26
Lake Wappapello
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Puxico

Check out the local area in Puxico—home to attractions like Mark Twain National Forest and Mingo Wilderness.

See all hotels in Puxico

Top Puxico Hotel Reviews

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

10/10 Excellent
"Clean property with very friendly staff. "
Nancy 1-night trip
Posted 3 days ago
Drury Inn & Suites Poplar Bluff

Frequently asked questions

What's the best place for a stay in Puxico?

Motel 6 Poplar Bluff, MO, located 19.4 mi (31.3 km) from the heart of Puxico, is a top choice for your stay based on our traveler data. Two other choices for your trip to the area are Fairfield Inn & Suites by Marriott Poplar Bluff and Holiday Inn Poplar Bluff by IHG. See all available top hotels, or vacation rentals in Puxico.

If I need to cancel my hotel reservation in Puxico, will I receive a refund?

Yes, you'll find most hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Puxico.

Where can I learn more about changing or cancelling my trip to Puxico?

To find more details about picking new dates or cancelling your trip to Puxico, click here.

What is staying in Puxico like?

Travelers to Puxico will find plenty to explore and enjoy. There are 51 hotels and other accommodations in the surrounding area. Find out more about Puxico.

What is there to see in Puxico?

A couple of favorite places to visit are Mark Twain National Forest and Mingo Wilderness. You'll also find Lake Wappapello and Lake Wappapello State Park in the area. Check out what more to see and do in Expedia's Puxico guide.

What's the seasonal weather like in Puxico?

The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Puxico is 59 inches.