Photo by Erdem Yücel

Find Luxury Hotels in Pythagorio

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Pythagorio Luxury Hotels

Tonight
Nov 7 - Nov 8
Tomorrow
Nov 8 - Nov 9
This weekend
Nov 7 - Nov 9
Next weekend
Nov 14 - Nov 16

Top Pythagorio Luxury Hotels

2 outdoor pools, pool umbrellas, sun loungers
Doryssa Seaside Resort

Doryssa Seaside Resort

5.0 star property
Samos
8.6 out of 10, Excellent, (153)
"nice and relaxing hotel very close to Pythagoreio center. "
United States
ilkay
Doryssa Seaside Resort
Indoor pool, outdoor pool, pool umbrellas, sun loungers
Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only

5.0 star property
Samos
9.4 out of 10, Exceptional, (86)
"Great private beach; friendly staff, wonderful views, good food."
Switzerland
Jiuan-Hua
Proteas Blu Resort - Adults Only
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Pythagorio Hotel Reviews

Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only

10/10 Excellent
"Perfect"
David 9-night trip
Posted 2 months ago
Proteas Blu Resort - Adults Only
Doryssa Seaside Resort

Doryssa Seaside Resort

10/10 Excellent
"nice and relaxing hotel very close to Pythagoreio center. "
ilkay 4-night trip
Posted 6 months ago
Doryssa Seaside Resort

Explore a world of travel with Expedia

Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Pythagorio?
During your visit, you might want to enjoy the port which Pythagorio is known for.
What's the best luxury place to stay in Pythagorio?
Casa Cook Samos is a luxury hotel with a beachfront restaurant and 2 bars, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Proteas Blu Resort - Adults Only and Doryssa Seaside Resort are other upscale choices for your stay.
When can I expect good weather in Pythagorio?
Planning for the weather is an important factor for making your trip to Pythagorio a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 77°F, while the coldest months are January and February with an average of 55°F. Average annual precipitation for Pythagorio is 33 inches.
What's there to see and do in Pythagorio?
Experience Pythagorio with a stop at Samos Pythagorion Archaeological Museum, Pythagoreion, and Glicorisa Beach. If you have spare time during your trip, you might want to make a stop at Mykali Beach and Castle of Lycurgus.