Find hotels in San Francisco, Guayaquil from ₩20,765
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Discover 389 San Francisco hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.
Our top choices for San Francisco hotels

Villa Celeste - VC
Villa Celeste - VC

Malecon Guesthouse
Malecon Guesthouse

DC Suites Aeropuerto
DC Suites Aeropuerto

Hotel Dorado
Hotel Dorado

Tropical Inn
Tropical Inn

Hotel del Parque
Hotel del Parque
Where to stay in San Francisco
Downtown Guayaquil
Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Central Market and Sports Federation of Guayas while you're in town.
Ecuador
Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.
Puerto Santa Ana
Well-liked for its restaurants and river views, you might stop by Santa Ana Hill and La Perla while you're exploring Puerto Santa Ana and the surrounding neighborhoods.
Kennedy
Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or Policentro while you're exploring the area.
Urdesa
Urdesa is well-liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to San Marino Mall or Policentro.