Sanctuary Vacations

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    Save up to ₩234,741 when you book a flight and hotel together*

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    With over 300,000 hotels worldwide, it's easy to create a perfect package

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Where to stay in Sanctuary

Find the best Sanctuary areas and neighborhoods for the activities you enjoy most. Learn more about Sanctuary
Fort Myers featuring a sandy beach

West End

3 out of top 10 points of interest in this area

While visiting West End, you might make a stop by sights like J. N. Ding Darling National Wildlife Refuge and Bowman's Beach.

Find hotels in West End

Sanctuary Hotel Deals

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
The price is ₩219,637 per night from Jan 6 to Jan 7
₩219,637
₩277,110 total
Jan 6 - Jan 7, 2026
includes taxes & fees
9/10 Wonderful! (1,020 reviews)
Clean rooms lovely view of Beach and pool area.

Reviewed on Dec 22, 2025

Lani Kai Beachfront Resort
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
The price is ₩650,481 per night from Dec 30 to Dec 31
₩650,481
₩797,967 total
Dec 30 - Dec 31
includes taxes & fees
8.8/10 Excellent! (1,724 reviews)
The room was spotless. The crew were friendly and helpful. The swimming pool was the biggest I’ve ever seen. The location was perfect. Id come back for sure.

Reviewed on Dec 24, 2025

Margaritaville Beach Resort Fort Myers
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4 out of 5
17260 Harbour Pointe Dr Fort Myers FL
Fully refundableReserve now, pay when you stay
The price is ₩460,646 per night from Jan 6 to Jan 7
₩460,646
₩549,721 total
Jan 6 - Jan 7, 2026
includes taxes & fees
8.4/10 Very Good! (1,001 reviews)
We stayed at a suite (880) facing the bay which was an amazing view and balcony Positives: location - right before sanibel causeway , 2 pools, not many “rules and regs” like other resorts where you have to pay for lost towels, tip umbrella guys, etc - mini beach area was a bonus, very easy/ casual ...

Reviewed on Dec 24, 2025

Marriott Sanibel Harbour Resort & Spa
See all 12,916 properties in Sanctuary
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Sanctuary vacation package cost?
Starting from as little as , you can tailor your Sanctuary package the way you want. Simply combine hotels, flights and car rentals and we'll reward you with discounts.
How do I get a cheap travel package to Sanctuary?
Booking a flight and hotel together with Expedia won't just save you time — it'll save you a pretty penny too. A Sanctuary vacation package makes it easy to organize your dream adventure. With more than 550 airlines across the world to choose from, finding convenient flights that suit your schedule won't be hard. On top of that, we've got over 1,000,000 properties globally to select from. Now that's what we call choice. No matter who you are, Expedia brings the world within your reach.
Where should I stay in Sanctuary?
A getaway to Sanctuary wouldn't be complete without seeing Bowmans Beach, Blind Pass Beach and Castaways Marina. Spend your evenings close to these top attractions and make sightseeing a breeze.
How far in advance should I book my Sanctuary vacation?
Reward yourself with the biggest variety at the lowest prices by booking your vacation to Sanctuary early. Airlines typically release flight tickets around 12 months prior to departure, so start your planning ASAP. That said, Expedia is committed to providing you with the best deals around, so it's never a bad time to book your dream vacation!
What does an Expedia Sanctuary travel package include?
That depends on what you're after. If you're traveling by yourself, you might decide to bundle flights and hotels. Taking the whole family to Sanctuary? A travel package that includes hotels, rental cars and flights might suit you better. Expedia gives you the freedom and flexibility to tailor-make your travel package.
What should I know before booking a Sanctuary travel package?
Booking all the parts of your escape together is a terrific way to save. Bundle your car rentals, airfares and hotels into one package. But you're not limited to hotels. Expedia offers all types of properties, including vacation rentals like beachfront villas and spacious residences. The list goes on!
Can I choose my airline with a Sanctuary Expedia vacation package?
Most definitely. Expedia has over 550 partner airlines to choose from globally. With so much choice, finding the perfect carrier to whisk you away to Sanctuary won't be difficult.
If I'm not able to travel, can I cancel my Sanctuary vacation package?
Don't stress if you're rethinking your Sanctuary vacation package — it's possible to change or amend your booking. And if you've booked it within the last 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your hotel, airline or car rental company. We totally understand life can sometimes throw you a curveball, so make your way to our Customer Service Portal if that happens. When you're ready to make changes, we'll be here to help.

Discover the most popular places to visit in Sanctuary

J. N. Ding Darling National Wildlife Refuge showing a bridge as well as a small group of people

J. N. Ding Darling National Wildlife Refuge

4.5/5(39 reviews)

See almost anything that flies, swims or crawls in Florida in this protected area. Become acquainted with wildlife while learning about varied species.

J. N. Ding Darling National Wildlife Refuge

Sanibel and Captiva Island Visitor's Center

5/5(4 reviews)

Sanibel and Captiva Island Visitor's Center is just one of the places to see in Sanibel, so why not enjoy the other things to explore during your travels? Stroll along the seaside or discover the beautiful sunsets in this family-friendly area.

Sanibel and Captiva Island Visitor's Center
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.