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Find hotels in Santa Ana, Panama City from ₩32,819

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Discover 1,516 Santa Ana hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

ART CASCO The Hotel

2.0 star property
7.2 out of 10, Good, (7)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
The price is ₩33,953
₩37,343 total
includes taxes & fees
Aug 24 - Aug 25
ART CASCO The Hotel

Casco View Apartments

3.5 star property
9.4 out of 10, Exceptional, (44)
"I liked the buildings quietness and modern style."
The price is ₩100,240
₩110,264 total
includes taxes & fees
Aug 24 - Aug 25
Casco View Apartments

Hotel República

2.0 star property
6.6 out of 10, (173)
"The wifi is strong enough to use for work. "
The price is ₩40,469
₩44,516 total
includes taxes & fees
Aug 24 - Aug 25
Hotel República

Hostal La Cigarra

2.5 star property
7.6 out of 10, Good, (50)
"Great location to walk around the casco! Street parking available for free! Prices are really affordable! Staff was really helpful "
The price is ₩32,819
₩36,098 total
includes taxes & fees
Aug 24 - Aug 25
Hostal La Cigarra

Hotel Riazor

3.0 star property
3.8 out of 10, (10)
"Rough neighborhood "
The price is ₩37,356
₩41,092 total
includes taxes & fees
Aug 24 - Aug 25
Hotel Riazor

La Manzana by Wynwood House

3.5 star property
7.0 out of 10, Good, (13)
"Great hotel. Very close to Casco viejo"
The price is ₩67,242
₩101,638 total
includes taxes & fees
Aug 24 - Aug 25
La Manzana by Wynwood House

Room-sofa Bed Stay Rooftop Pool & Gym, A

2.0 star property
2.0 out of 10, (1)
"You pay for a space in the apartment, it’s not the whole apartment be careful. The owner or whoever manages doesn’t give care about you as costumers they just want the money"
The price is ₩183,366
₩201,703 total
includes taxes & fees
Aug 24 - Aug 25
Room-sofa Bed Stay Rooftop Pool & Gym, A

Casa Quijano 06 By Wynwood House

4.0 star property
9.4 out of 10, Exceptional, (3)
"The apartment itself was very nice, very spacious, clean, newer furniture. Just know it’s on the third floor and there is no elevator. I didn’t see a sign on the building so it was a bit tricky to figure out which door to go to after being dropped off by the Uber. Email communication from property with building entry code and picture of the property was helpful. There are two balconies but all you really see is the apartment immediately in front of you, and so just know people can see you if you...
The price is ₩99,618
₩155,238 total
includes taxes & fees
Aug 30 - Aug 31
Casa Quijano 06 By Wynwood House

w Charming 1BR in Santa Ana s Best Area

2.0 star property
The price is ₩79,518
₩136,781 total
includes taxes & fees
Aug 30 - Aug 31
w Charming 1BR in Santa Ana s Best Area

Crowne Plaza Panama Airport by IHG

4.0 star property
8.4 out of 10, Very Good, (2186)
"I love how convenient it is for people to get to the hotel , the food was great , service was great too! "
The price is ₩157,728
₩173,501 total
includes taxes & fees
Sep 11 - Sep 12
Crowne Plaza Panama Airport by IHG

Central Hotel Panama Casco Viejo

4.0 star property
9.0 out of 10, Wonderful, (975)
"Love the location and the restaurant inside the hotel was phenomenal."
The price is ₩239,829
₩263,812 total
includes taxes & fees
Aug 27 - Aug 28
Central Hotel Panama Casco Viejo

TRYP by Wyndham Panamá Centro

3.5 star property
9.0 out of 10, Wonderful, (1003)
"location was amazing and very comfortable for the price"
The price is ₩116,221
₩127,843 total
includes taxes & fees
Aug 24 - Aug 25
TRYP by Wyndham Panamá Centro

Hotel Coral Suites

3.5 star property
9.0 out of 10, Wonderful, (1000)
"Nice Hotel "
The price is ₩95,882
₩105,470 total
includes taxes & fees
Aug 24 - Aug 25
Hotel Coral Suites

Megapolis Hotel Panamá

4.5 star property
8.4 out of 10, Very Good, (1040)
"I love it here, had an amazing experience staff was so great, will definitely stay here again"
The price is ₩173,021
₩190,323 total
includes taxes & fees
Sep 6 - Sep 7
Megapolis Hotel Panamá

Hospedium Princess Hotel Panama

3.5 star property
7.6 out of 10, Good, (588)
"I enjoyed my stay"
The price is ₩60,014
₩66,015 total
includes taxes & fees
Aug 24 - Aug 25
Hospedium Princess Hotel Panama

Riande Aeropuerto Hotel & Casino

4.0 star property
8.4 out of 10, Very Good, (1885)
"Lovely setting with quick shuttle service to the airport!"
The price is ₩200,708
₩220,779 total
includes taxes & fees
Sep 18 - Sep 19
Riande Aeropuerto Hotel & Casino

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (4190)
"Very convenient location, friendly staff and all around beautiful hotel."
The price is ₩151,037
₩166,141 total
includes taxes & fees
Aug 26 - Aug 27
Hotel Riu Plaza Panama

Principe Hotel and Suites

3.0 star property
9.0 out of 10, Wonderful, (1438)
"Great place , super staff "
The price is ₩80,939
₩89,033 total
includes taxes & fees
Aug 24 - Aug 25
Principe Hotel and Suites

Plaza Paitilla Inn Hotel

3.5 star property
9.4 out of 10, Exceptional, (2099)
"nice place, good breakfast"
The price is ₩218,761
₩240,637 total
includes taxes & fees
Aug 24 - Aug 25
Plaza Paitilla Inn Hotel

Waldorf Astoria Panama

5.0 star property
9.0 out of 10, Wonderful, (1001)
"Great hotel for my recent stay in Panam "
The price is ₩304,595
₩335,055 total
includes taxes & fees
Sep 20 - Sep 21
Waldorf Astoria Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

1 out of top 10 points of interest in this area

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

San Francisco

1 out of top 10 points of interest in this area

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Top Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Santa Ana?

Santa Ana is a neighborhood that travelers like for its seafood restaurants, shopping, and parks. Are you looking for Santa Ana travel tips? Be sure to check out Cinta Costera and Avenida Balboa while you're in the neighborhood.

Where is the best hotel for a stay in Santa Ana?

Based on Expedia customer reviews, Hotel República is the highest ranked property in Santa Ana. This hotel is a short 4-minute walk from Avenida Balboa, and it offers a rooftop terrace and free WiFi. Another top choice in the area is Hostal La Cigarra.

How many hotels can I expect to find in Santa Ana?

Expedia has 99 hotels and other accommodations in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.

If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

Yes! Most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in Santa Ana.

Where can I learn more about changing or cancelling my trip to Santa Ana?

To find more details about picking new dates or cancelling your trip to Santa Ana, head over to our customer service page.

What is there to do in this Panama City neighborhood?

If you're looking forward to a day of shopping in Santa Ana, consider Avenida Central or Avenida Balboa, and pick out the perfect souvenir. A visit to Cinta Costera is also worth the trip while you're discovering the neighborhood. Albrook Shopping Mall, Amador Theater, and Museum of Contemporary Art Panama are just a few of the places to visit in and around Santa Ana. When you're sightseeing in Panama City, Mi Pueblito and Iglesia de la Merced are also worth a stop.