Find hotels in Santa Clara, Panama City from ₩83,556

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Our top choices for Santa Clara hotels

A buffet with various food items including fruits, juices, and cheeses.

1. Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
3.2 km from Santa Clara
9.2 out of 10, Wonderful, (1,006 reviews)
"Very nice, easy access to airport"
United States
Hector
The price is ₩138,167
₩151,983 total
includes taxes & fees
Nov 27 - Nov 28
Courtyard by Marriott Panama Metromall
A modern hotel with a prominent entrance, multiple floors, and a well-lit facade.

2. Aloft by Marriott Panama

Aloft by Marriott Panama
3.5 star property
San Francisco, 6.1 km from Santa Clara
8.8 out of 10, Excellent, (1,012 reviews)
"It was a great stay! I would stay here again!"
United States
Brittney
The price is ₩168,272
₩185,099 total
includes taxes & fees
Nov 14 - Nov 15
Aloft by Marriott Panama
A hotel entrance with a central water feature, seating areas, and potted plants.

3. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz, 2.8 km from Santa Clara
9.6 out of 10, Exceptional, (772 reviews)
"Everything was top notch"
United States
Denis
The price is ₩429,042
₩471,953 total
includes taxes & fees
Nov 27 - Nov 28
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A modern urban area with high-rise buildings, a prominent glass structure, and a well-maintained street with palm trees.

4. The Westin Panama

The Westin Panama
4.0 star property
Costa del Este, 3 km from Santa Clara
9.0 out of 10, Wonderful, (356 reviews)
"Hotel was ok"
United Kingdom
Luke
The price is ₩381,803
₩419,983 total
includes taxes & fees
Nov 27 - Nov 28
The Westin Panama
A balcony with wicker chairs and a view of the cityscape.

5. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco, 6.6 km from Santa Clara
9.6 out of 10, Exceptional, (1,425 reviews)
"Great location and breakfast buffet was great"
United States
Luis
The price is ₩150,865
₩165,951 total
includes taxes & fees
Nov 9 - Nov 10
Ramada Plaza by Wyndham Panama Punta Pacifica
A swimming pool with lounge chairs and palm trees, surrounded by modern buildings.

6. Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco, 6.1 km from Santa Clara
8.8 out of 10, Excellent, (1,002 reviews)
"Clean rooms, comfy bed, helpful staff! Breakfast buffet was very complete with different options"
United States
Nicole
The price is ₩249,506
₩274,457 total
includes taxes & fees
Nov 13 - Nov 14
Sheraton Grand Panama
A rooftop pool with a city view, lounge chairs, and a clear sky.

7. Corporate Stays Arcadia | Executive Furnished Apartments

Corporate Stays Arcadia | Executive Furnished Apartments
4.0 star property
Costa del Este, 2.8 km from Santa Clara
9.2 out of 10, Wonderful, (420 reviews)
"Property was in a great location."
United States
Howard
The price is ₩110,588
₩190,731 total
includes taxes & fees
Nov 22 - Nov 23
Corporate Stays Arcadia | Executive Furnished Apartments
A pool area with lounge chairs, umbrellas, and a bridge over the water.

8. Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
8.7 km from Santa Clara
8.6 out of 10, Excellent, (1,817 reviews)
"Very nice and clean hotel, staff very friendly and helpful, good breakfast, really enjoyed"
United States
Lidia
The price is ₩147,800
₩162,580 total
includes taxes & fees
Nov 9 - Nov 10
Riande Aeropuerto Hotel & Casino
A swimming pool with a clear water surface, surrounded by a covered area with lounge chairs and a bar area.

9. Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
10.2 km from Santa Clara
8.6 out of 10, Excellent, (2,786 reviews)
"Great stay and very accommodating staff"
United States
Duran
The price is ₩185,679
₩213,258 total
includes taxes & fees
Nov 19 - Nov 20
Crowne Plaza Panama Airport by IHG
A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.

10. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 8 km from Santa Clara
9.0 out of 10, Wonderful, (6,200 reviews)
"The rooms were great, breakfast was enjoyable"
United States
Ashford J.
The price is ₩180,147
₩198,162 total
includes taxes & fees
Dec 1 - Dec 2
Hotel Riu Plaza Panama
A modern, well-lit buffet area with a variety of food items and neatly arranged plates.

11. Best Western El Dorado Panama Hotel

Best Western El Dorado Panama Hotel
3.0 star property
Bethania, 7.9 km from Santa Clara
9.0 out of 10, Wonderful, (816 reviews)
"Everything is very clean and the staff super helpfull!"
United States
Kira
The price is ₩136,529
₩150,182 total
includes taxes & fees
Nov 18 - Nov 19
Best Western El Dorado Panama Hotel
A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.

12. Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
San Francisco, 7.2 km from Santa Clara
9.0 out of 10, Wonderful, (1,004 reviews)
"The location was perfect for the things I had planed."
United States
Marine
The price is ₩179,030
₩196,933 total
includes taxes & fees
Nov 21 - Nov 22
Courtyard by Marriott Panama Multiplaza Mall
A poolside area with lounge chairs and a view of the ocean.

13. JW Marriott Panama

JW Marriott Panama
5.0 star property
Punta Pacifica, 7.8 km from Santa Clara
9.2 out of 10, Wonderful, (1,001 reviews)
"Excellent location, spacious , well maintened. Staff was also very helpful ."
Canada
Luz Elizabeth
The price is ₩446,723
₩491,395 total
includes taxes & fees
Nov 27 - Nov 28
JW Marriott Panama
A modern hotel lobby with glass doors, potted plants, a reception desk, and a seating area.

14. Hotel y Casino Central Park Panama

Hotel y Casino Central Park Panama
3.0 star property
Bethania, 7.8 km from Santa Clara
7.6 out of 10, Good, (505 reviews)
"The rooms were clean, spacious, the staff was very helpful, breakfast options limited but was good"
United States
Shadé
The price is ₩83,556
₩91,912 total
includes taxes & fees
Nov 9 - Nov 10
Hotel y Casino Central Park Panama
A covered outdoor seating area with a view of a city skyline and water.

15. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
Punta Paitilla, 8.4 km from Santa Clara
9.4 out of 10, Exceptional, (2,244 reviews)
"great stay"
Canada
Davlin
The price is ₩160,359
₩176,395 total
includes taxes & fees
Nov 9 - Nov 10
Plaza Paitilla Inn Hotel
A modern hotel entrance with a prominent 'NOVOTEL' sign, large glass windows, and geometric light patterns on the facade.

16. Novotel Panama City

Novotel Panama City
4.0 star property
El Cangrejo, 7.5 km from Santa Clara
9.2 out of 10, Wonderful, (1,305 reviews)
"Nice place to stay."
United States
CARLOS
The price is ₩143,765
₩158,142 total
includes taxes & fees
Nov 10 - Nov 11
Novotel Panama City
A high-rise building with a modern architectural design, featuring a grid of windows and balconies.

17. Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
Punta Paitilla, 8.2 km from Santa Clara
8.6 out of 10, Excellent, (1,854 reviews)
"Loved our stay there"
United States
Amanda
The price is ₩228,578
₩251,436 total
includes taxes & fees
Nov 11 - Nov 12
Megapolis Hotel Panamá
A rooftop pool with lounge chairs and a city skyline view.

18. TRYP by Wyndham Panamá Centro

TRYP by Wyndham Panamá Centro
3.5 star property
El Cangrejo, 8.3 km from Santa Clara
9.0 out of 10, Wonderful, (1,002 reviews)
"Decent stay for the money."
Canada
Larry
The price is ₩124,173
₩136,597 total
includes taxes & fees
Nov 30 - Dec 1
TRYP by Wyndham Panamá Centro
A dining area with a glass table, wicker chairs, a plate of fruit, and a cocktail glass.

19. The Executive Hotel

The Executive Hotel
3.5 star property
Campo Alegre, 8.4 km from Santa Clara
9.2 out of 10, Wonderful, (1,310 reviews)
"The staff were very helpful and friendly, also it was a nice location to restaurants and some attractions"
United States
Shereka
The price is ₩108,991
₩119,886 total
includes taxes & fees
Nov 29 - Nov 30
The Executive Hotel
A poolside area with lounge chairs and umbrellas, overlooking a clear blue sea and a city skyline.

20. Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
Punta Paitilla, 7.8 km from Santa Clara
9.2 out of 10, Wonderful, (695 reviews)
"Great place!"
United States
david
The price is ₩281,250
₩309,375 total
includes taxes & fees
Dec 7 - Dec 8
Residence Inn by Marriott Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Santa Clara

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A buffet with various food items including fruits, juices, and cheeses.
Courtyard by Marriott Panama Metromall
4.0 star property
9.2
Wonderful
1,006 reviews
View
A rooftop pool with a city view, lounge chairs, and a clear sky.
Corporate Stays Arcadia | Executive Furnished Apartments
4.0 star property
9.2
Wonderful
420 reviews
View
A balcony with wicker chairs and a view of the cityscape.
Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
9.6
Exceptional
1,425 reviews
View
A hotel entrance with a central water feature, seating areas, and potted plants.
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
9.6
Exceptional
772 reviews
View
A modern hotel with a prominent entrance, multiple floors, and a well-lit facade.
Aloft by Marriott Panama
3.5 star property
8.8
Excellent
1,012 reviews
View

Where to stay in Santa Clara

Find the best Santa Clara areas and neighborhoods for the activities you enjoy most.
A coastal cityscape with a prominent church tower, a river, and distant mountains.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

A modern, spiraling skyscraper with a unique design, surrounded by other buildings in an urban setting.
Photo by Fabiola Tile
Open Photo by Fabiola Tile

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station.

A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

A bridge over a body of water with several boats.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

A building with three arched windows, a balcony with wrought iron railings, and a tiled roof.

San Felipe

If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.

Top Santa Clara Hotel Reviews

A buffet with various food items including fruits, juices, and cheeses.
Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
San Antonio

10/10 Excellent

Good property
United States
Carlos
Reviewed April 20, 2025
Courtyard by Marriott Panama Metromall

Frequently Asked Questions

What is Santa Clara like?

Travelers will be sure to find plenty to entertain them in Panama City's Santa Clara neighborhood.

If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?

Yes! You'll find that most hotel reservations are refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within 24 hours of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to review the best options available in Santa Clara.

Where can I learn more about changing or cancelling my trip to Santa Clara?

To access more information about picking new dates or cancelling your trip to Santa Clara, go to https://www.expedia.com/service/.

What are the top things to see and do in Santa Clara?

A few places to visit in the area around Santa Clara include Estadio Rommel Fernandez, Plaza de Francia, and Atrio Mall. While you're out sightseeing, Monte Oscuro and Los Pueblos Commercial Center are a couple of additional sights to visit in Panama City.