Find hotels in Santa Clara, Panama City from ₩29,180

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Discover 1,524 Santa Clara hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for Santa Clara hotels

Riande Aeropuerto Hotel & Casino

4.0 star property
8.4 out of 10, Very Good, (1890)
"Lovely setting with quick shuttle service to the airport!"
The price is ₩185,575
₩204,132 total
includes taxes & fees
Aug 28 - Aug 29
Riande Aeropuerto Hotel & Casino

Crowne Plaza Panama Airport by IHG

4.0 star property
8.4 out of 10, Very Good, (2200)
"I love how convenient it is for people to get to the hotel , the food was great , service was great too! "
The price is ₩158,404
₩174,244 total
includes taxes & fees
Sep 11 - Sep 12
Crowne Plaza Panama Airport by IHG

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
9.6 out of 10, Exceptional, (599)
"The staff was very friendly. "
The price is ₩306,498
₩337,148 total
includes taxes & fees
Sep 20 - Sep 21
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Courtyard by Marriott Panama Metromall

4.0 star property
8.8 out of 10, Excellent, (1007)
"Lovely hotel in a great and safe location"
The price is ₩136,311
₩149,942 total
includes taxes & fees
Sep 6 - Sep 7
Courtyard by Marriott Panama Metromall

Villa Caprichosa

3.0 star property
10.0 out of 10, Exceptional, (32)
"We loved the place and the attention given by the staff."
The price is ₩260,533
₩286,586 total
includes taxes & fees
Aug 27 - Aug 28
Villa Caprichosa

The Westin Panama

4.0 star property
8.8 out of 10, Excellent, (290)
"Restaurant was under construction and food nearby was t the best but the hotel itself and staff were fantastic. "
The price is ₩261,700
₩287,870 total
includes taxes & fees
Aug 30 - Aug 31
The Westin Panama

Arcadia Condo Suites

2.5 star property
9.2 out of 10, Wonderful, (57)
"its a very nice place "
The price is ₩67,808
₩138,784 total
includes taxes & fees
Aug 27 - Aug 28
Arcadia Condo Suites

Sheraton Grand Panama

4.0 star property
8.6 out of 10, Excellent, (935)
"A great stay. "
The price is ₩186,333
₩204,967 total
includes taxes & fees
Sep 1 - Sep 2
Sheraton Grand Panama

W Panama

5.0 star property
8.8 out of 10, Excellent, (1008)
"Great hotel "
The price is ₩287,906
₩316,696 total
includes taxes & fees
Sep 14 - Sep 15
W Panama

Waymore Hotel Spa & Casino

4.0 star property
9.2 out of 10, Wonderful, (437)
"Thank you really like staying there first time"
The price is ₩112,536
₩123,790 total
includes taxes & fees
Aug 27 - Aug 28
Waymore Hotel Spa & Casino

MARINN Tropical Vibes Hotel

3.5 star property
8.2 out of 10, Very Good, (127)
"Room cleaned everyday, staffs are nice, friendly and honest. Shops and restaurants are just downstairs of the hotel, very convenient. Don't like the noise outside late at night on the weekend. Other than that love it there."
The price is ₩97,266
₩106,993 total
includes taxes & fees
Sep 1 - Sep 2
MARINN Tropical Vibes Hotel

Ramada Plaza By Wyndham Panama Punta Pacífica

4.0 star property
9.6 out of 10, Exceptional, (1024)
"Very nice place and staff"
The price is ₩161,530
₩177,683 total
includes taxes & fees
Sep 2 - Sep 3
Ramada Plaza By Wyndham Panama Punta Pacífica

Central Hotel Panama Casco Viejo

4.0 star property
9.0 out of 10, Wonderful, (976)
"The hotel is beautiful and in perfect location. On site staff was very friendly and helpful. Would definitely stay here again."
The price is ₩235,287
₩258,816 total
includes taxes & fees
Sep 1 - Sep 2
Central Hotel Panama Casco Viejo

Radisson Hotel Panama Canal

4.5 star property
8.4 out of 10, Very Good, (1001)
"Very nice hotel!"
The price is ₩120,471
₩132,518 total
includes taxes & fees
Sep 2 - Sep 3
Radisson Hotel Panama Canal

The Beach House

3.0 star property
8.4 out of 10, Very Good, (394)
"This was a great stay! We enjoyed the view from our balcony, I mean, on one side Panama City and on the other side Amador and the Pacific. We even enjoyed watching raccoons play on the surf. The breakfast was ok. But Nextdoor was the great Ranchito Restaurant which served like the best sangria ever. I had a seafood soup which was very tasty. So I am definitely going back on my next stay."
The price is ₩111,981
₩123,180 total
includes taxes & fees
Aug 27 - Aug 28
The Beach House

Hyatt Regency Panama City

4.5 star property
10.0 out of 10, Exceptional, (60)
"Friendly staff.. great food and in a convenient location to allow pick up for tours"
The price is ₩216,763
₩238,439 total
includes taxes & fees
Sep 14 - Sep 15
Hyatt Regency Panama City

Waldorf Astoria Panama

5.0 star property
9.0 out of 10, Wonderful, (1003)
"Great hotel for my recent stay in Panam "
The price is ₩305,901
₩336,491 total
includes taxes & fees
Sep 20 - Sep 21
Waldorf Astoria Panama

Plaza Paitilla Inn Hotel

3.5 star property
9.4 out of 10, Exceptional, (2102)
"nice place, good breakfast"
The price is ₩219,699
₩241,669 total
includes taxes & fees
Aug 27 - Aug 28
Plaza Paitilla Inn Hotel

American Trade Hotel

4.5 star property
9.4 out of 10, Exceptional, (552)
"Beautiful property and friendly staff!"
The price is ₩301,885
₩332,073 total
includes taxes & fees
Sep 8 - Sep 9
American Trade Hotel

Hotel San Felipe

4.0 star property
9.4 out of 10, Exceptional, (185)
"Great location, walkable to tourists attractions and restaurants, excellent staff "
The price is ₩166,321
₩182,953 total
includes taxes & fees
Aug 27 - Aug 28
Hotel San Felipe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Clara

Find the best Santa Clara areas and neighborhoods for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

1 out of top 10 points of interest in this area

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

San Francisco

1 out of top 10 points of interest in this area

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Top Santa Clara Hotel Reviews

Frequently asked questions

What is Santa Clara like?

Travelers will be sure to find plenty to entertain them in Panama City's Santa Clara neighborhood.

If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?

Yes! You'll find that most hotel reservations are refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within 24 hours of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to review the best options available in Santa Clara.

Where can I learn more about changing or cancelling my trip to Santa Clara?

To access more information about picking new dates or cancelling your trip to Santa Clara, go to https://www.expedia.com/service/.

What are the top things to see and do in Santa Clara?

A few places to visit in the area around Santa Clara include Estadio Rommel Fernandez, Plaza de Francia, and Atrio Mall. While you're out sightseeing, Monte Oscuro and Los Pueblos Commercial Center are a couple of additional sights to visit in Panama City.