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Compare 1,817 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Our top choices for Santa Cruz hotels

Mala Vecindad Centro Historico

3.0 star property
8.8 out of 10, Excellent, (62)
"Friendly, supportive staff members. The place has a very unique decoration, as well as a rooftop with an impressive view of the city. It’s a quiet and relaxing place to rest but also to enjoy with family and friends."
The price is ₩24,190
₩52,646 total
includes taxes & fees
Sep 5 - Sep 6
Mala Vecindad Centro Historico

Verticca Hotel

3.0 star property
9.4 out of 10, Exceptional, (183)
"Good place to stay "
The price is ₩143,478
₩172,173 total
includes taxes & fees
Aug 31 - Sep 1
Verticca Hotel

Hotel Madeira

3.5 star property
8.8 out of 10, Excellent, (163)
"Everything is okay "
The price is ₩52,767
₩63,320 total
includes taxes & fees
Aug 31 - Sep 1
Hotel Madeira

Hotel Finca Las Hortensias

3.0 star property
8.2 out of 10, Very Good, (179)
"Front desk service was excellent, the food was delicious and the service from Saul was wonderful. "
The price is ₩80,388
₩96,466 total
includes taxes & fees
Aug 31 - Sep 1
Hotel Finca Las Hortensias

Downtown Treasure Place

2.5 star property
8.8 out of 10, Excellent, (651)
"This ok, it's very nice, it's beautiful, "
The price is ₩28,823
₩34,876 total
includes taxes & fees
Sep 1 - Sep 2
Downtown Treasure Place

Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG

3.5 star property
9.4 out of 10, Exceptional, (816)
"The hotel is very well situated"
The price is ₩150,778
₩180,933 total
includes taxes & fees
Sep 5 - Sep 6
Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG

Hotel Brasilia

3.0 star property
9.0 out of 10, Wonderful, (1007)
"It was a fantastic experience"
The price is ₩81,041
₩96,844 total
includes taxes & fees
Aug 31 - Sep 1
Hotel Brasilia

Hotel Coacalco

2.5 star property
7.6 out of 10, Good, (60)
"Amazing room service"
The price is ₩36,204
₩41,997 total
includes taxes & fees
Sep 1 - Sep 2
Hotel Coacalco

Hotel La Rosa - Adults Only

2.5 star property
8.2 out of 10, Very Good, (414)
"Excelente "
The price is ₩29,456
₩35,200 total
includes taxes & fees
Aug 31 - Sep 1
Hotel La Rosa - Adults Only

Mala Vecindad Beer Hotel

3.0 star property
8.0 out of 10, Very Good, (197)
"A BEAUTIFUL hotel overall. Would repeat the stay."
The price is ₩17,228
₩44,326 total
includes taxes & fees
Aug 31 - Sep 1
Mala Vecindad Beer Hotel

Hotel Piet

2.0 star property
7.4 out of 10, Good, (127)
"Nice hotel staff."
The price is ₩19,637
₩23,466 total
includes taxes & fees
Sep 4 - Sep 5
Hotel Piet

City Express by Marriott Ciudad de México La Villa

3.0 star property
8.8 out of 10, Excellent, (1009)
"Very clean place, the staff very friendly at all times. Very close to the basilica, would stay there again"
The price is ₩94,285
₩112,671 total
includes taxes & fees
Sep 6 - Sep 7
City Express by Marriott Ciudad de México La Villa

Autoparador del Valle

3.0 star property
7.2 out of 10, Good, (5)
"Affordable nice room"
The price is ₩40,227
₩48,272 total
includes taxes & fees
Aug 31 - Sep 1
Autoparador del Valle

Lamartine Boutique Hotel Polanco

5.0 star property
10.0 out of 10, Exceptional, (14)
"Fantastic place. Beautiful, reasonable price and helpful staff."
The price is ₩335,219
₩400,587 total
includes taxes & fees
Sep 28 - Sep 29
Lamartine Boutique Hotel Polanco

Edgar Allan Poe 227 By Ömora

3.5 star property
10.0 out of 10, Exceptional, (23)
"Will definitely stay here again. Can’t say one bad thing about this place. "
The price is ₩122,248
₩146,083 total
includes taxes & fees
Sep 1 - Sep 2
Edgar Allan Poe 227 By Ömora

RHM Spaces - Santa Maria

2.0 star property
7.0 out of 10, Good, (57)
"Convenient place for 1-2 person stay"
The price is ₩17,511
₩20,926 total
includes taxes & fees
Aug 31 - Sep 1
RHM Spaces - Santa Maria

Gran Hotel Panorama

3.0 star property
8.4 out of 10, Very Good, (970)
"Friendly staff "
The price is ₩28,676
₩34,268 total
includes taxes & fees
Aug 31 - Sep 1
Gran Hotel Panorama

KALI La Raza Mexico City

2.5 star property
9.4 out of 10, Exceptional, (164)
"Great place to stay"
The price is ₩78,341
₩93,618 total
includes taxes & fees
Sep 1 - Sep 2
KALI La Raza Mexico City

Collection O Casa Anzures Thematic, Mexico City

3.0 star property
8.8 out of 10, Excellent, (115)
"A creative and unique space."
The price is ₩64,311
₩80,068 total
includes taxes & fees
Sep 17 - Sep 18
Collection O Casa Anzures Thematic, Mexico City

UTOPIC Polanco by ULIV

4.5 star property
9.0 out of 10, Wonderful, (618)
"It’s a good place to stay, specially if going for business purposes"
The price is ₩101,067
₩120,775 total
includes taxes & fees
Aug 31 - Sep 1
UTOPIC Polanco by ULIV
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Where is the best place for a stay in Santa Cruz?

Located 18.9 mi (30.5 km) from the heart of Santa Cruz, Hyatt Regency Mexico City is a top choice for your stay based on our traveler data. Two other options for your trip to the area are InterContinental Presidente Mexico City by IHG and Casa Olea. See all available top hotels, or vacation rentals in Santa Cruz.

If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?

Yes! You'll find that most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

Where can I learn more about changing or cancelling my trip to Santa Cruz?

To find more details about changing or cancelling your trip to Santa Cruz, head over to our customer service page.

What is staying in Santa Cruz like?

Those traveling to Santa Cruz are sure to enjoy the sights to see and things to do. There are 1817 hotels and other accommodations in the surrounding area. Find out more about Santa Cruz.

What is there to see in Santa Cruz?

Places to visit in the wider area include Hacienda La Concepcion, National Museum of the Viceroyalty, and San Marcos Power Center. You'll also find Xochitla Ecological Park and Arcos del Sitio in the area. Check out what more to see and do in Expedia's Santa Cruz guide.

What's the seasonal weather like in Santa Cruz?

The hottest months are usually April and May with an average temp of 64°F, while the coldest months are January and December with an average of 57°F. The rainiest months in Santa Cruz are August, July, September, and June, with each month seeing an average of 7 inches of rainfall.