Santa Cruz Vacations

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Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
Historical Center

Historical Center

8 out of top 10 points of interest in this area

Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.

Find hotels in Historical Center

Santa Cruz Hotel Deals

Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center

4 out of 5
Calle Santa Maria La Blanca 5 Seville Seville
Fully refundableReserve now, pay when you stay
The price is ₩166,467 per night from Jan 13 to Jan 14
₩166,467
₩183,113 total
Jan 13 - Jan 14, 2026
includes taxes & fees
9.2/10 Wonderful! (1,005 reviews)
staff were very courteous and happy to help with any and all requests. The hotel is quite charming and scenic, which I loved about it. only downside was, i think the heat in my room wasn’t working. but i was too lazy to ask about it; im sure they would have either fixed it or changed my room. The ...

Reviewed on Dec 20, 2025

Las Casas de la Judería, Sevilla Historic City Center
Hotel Amadeus Sevilla

Hotel Amadeus Sevilla

4 out of 5
Calle Farnesio 6 Seville Seville
Fully refundableReserve now, pay when you stay
The price is ₩189,259 per night from Jan 8 to Jan 9
₩189,259
₩208,185 total
Jan 8 - Jan 9, 2026
includes taxes & fees
9.6/10 Exceptional! (1,089 reviews)
Family run hotel, friendly and helpful. Great location

Reviewed on Dec 18, 2025

Hotel Amadeus Sevilla
Hotel Fernando III

Hotel Fernando III

4 out of 5
San Jose 21 Seville Seville
Fully refundableReserve now, pay when you stay
9.6/10 Exceptional! (1,528 reviews)
The whole hotel was spotless and the staff were so friendly. Location to historical centre in only minutes away on foot but also with good choices on same street as hotel for food and drinks.

Reviewed on Dec 10, 2025

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Hotel Fernando III
See all 433 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Cruz vacation package cost?
Get ready to book, because a trip to Santa Cruz starts from a tempting . When you combine your hotels, flights and car rentals into a package, you'll enjoy the biggest deals.
How do I get a cheap travel package to Santa Cruz?
Just think of all the fun things you could do in Santa Cruz with a pile of extra cash in your pocket. Watch your savings stack up when you combine your travel bookings into a Santa Cruz vacation package. You have plenty of choice when it comes to booking with Expedia too. In fact, you can select from over 550 airlines and 1,000,000 properties around the world. Whether you're enjoying a break with the whole family or traveling with someone special, exploring Santa Cruz is better with a package.
Where should I stay in Santa Cruz?
Most people who visit Santa Cruz put both Seville Cathedral and Alcázar on their must-see lists. Why not choose a hotel close to one of these iconic attractions?
What are the top hotels in Santa Cruz?
Puerta Catedral Holiday Suites and San Isidoro Hostel Sevilla are among the most well-known properties in Santa Cruz. Why not check out the rates and facilities at each and then make up your mind?
How far in advance should I book my Santa Cruz vacation?
Reserving your seat early with Expedia means one less thing to have to worry about. Most carriers advertise prices up to 12 months prior to take off. This is generally the cheapest time to book. If circumstances have left you booking late, great deals to Santa Cruz sometimes emerge in the weeks leading up to departure.
What does an Expedia Santa Cruz travel package include?
Hotels, car rentals and flights — we bring you the very best deals. All you'll have to do is decide on your ideal combination. Once you've made your booking, you can add on the fun stuff like activities and tours. Our travel packages make it easy to craft an awesome Santa Cruz trip.
What should I know before booking a Santa Cruz travel package?
You'll pick up impressive savings when you bundle your flights, hotels and rental cars into a package. Plus, booking everything in one place just makes things easier. So why waste your time or money? Whether you're putting together an upscale romantic escape or a budget family adventure, explore our vacation packages today.
Can I choose my airline with a Santa Cruz Expedia vacation package?
Yes — that's the beauty of an Expedia package. You're in control. We have more than 550 airline partners around the world, so you have loads of choice when organizing your Santa Cruz getaway.
If I'm not able to travel, can I cancel my Santa Cruz vacation package?
Yes, it's possible to cancel your Santa Cruz booking if your travel plans have changed. Whether you'll be charged a fee or not depends on your airline, hotel or car rental company. You may be able to change or cancel for free if you booked in the last 24 hours. Visit our Customer Service Portal to learn more.

Discover the most popular places to visit in Santa Cruz

Royal Alcázar showing a church or cathedral and religious elements

Royal Alcázar of Seville

5/5(735 reviews)

Discover a millennium’s worth of royal treasures in this architectural masterpiece in the heart of Seville.

Royal Alcázar of Seville
La Giralda which includes a castle and heritage architecture

Giralda Tower

4.5/5(496 reviews)

Once among the tallest religious monuments in the world, this former minaret is now the eye-catching bell tower to Seville Cathedral.

Giralda Tower
San Telmo Palace which includes heritage architecture

San Telmo Palace

Tour the striking interior and exterior of a palatial building that serves as the headquarters of the president of the autonomous region of Andalusia.

San Telmo Palace
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.