Find hotels in Seneca, SC from ₩88,565

Start date: Check-in selected.
To Date
End date: Check-out

    Change your mind

    Book hotels with free cancellation

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Oct 10 - Oct 11
Tomorrow
Oct 11 - Oct 12
This weekend
Oct 10 - Oct 12
Next weekend
Oct 17 - Oct 19

Filter by

Guest rating
Guest rating
Star rating

Compare 1,638 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Standard Cabin, 1 Queen Bed | Exterior

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

2.0 star property
9.6 out of 10, Exceptional, (40)
"Lovely stay! Highly recommend!!!"
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Lakeside Lodge Clemson
Aerial view

Lakeside Lodge Clemson

2.5 star property
9.0 out of 10, Wonderful, (1008)
"Very beautiful place to stay"
The price is ₩155,454
₩192,977 total
includes taxes & fees
Oct 12 - Oct 13
Lakeside Lodge Clemson
Quality Inn Seneca Clemson Area US-123
Free daily on-the-go breakfast

Quality Inn Seneca Clemson Area US-123

2.5 star property
8.0 out of 10, Very Good, (645)
"Staff was friendly very clean "
The price is ₩107,819
₩132,534 total
includes taxes & fees
Oct 19 - Oct 20
Quality Inn Seneca Clemson Area US-123
Tru by Hilton Seneca Clemson
Lobby

Tru by Hilton Seneca Clemson

2.5 star property
9.2 out of 10, Wonderful, (775)
"Clean room, staff was great, will always stay at this hotel in Clemson. Best place to stay!"
The price is ₩150,861
₩165,947 total
includes taxes & fees
Oct 19 - Oct 20
Tru by Hilton Seneca Clemson
Days Inn by Wyndham Seneca / Clemson Area
Room, 1 King Bed, Non Smoking | Desk, free cribs/infant beds, rollaway beds, free WiFi

Days Inn by Wyndham Seneca / Clemson Area

2.0 star property
6.8 out of 10, (702)
"Friendly staff easy check-in. "
The price is ₩103,042
₩113,346 total
includes taxes & fees
Oct 12 - Oct 13
Days Inn by Wyndham Seneca / Clemson Area
Fairfield Inn & Suites Seneca Clemson Univ Area
Balcony

Fairfield Inn & Suites Seneca Clemson Univ Area

2.5 star property
9.4 out of 10, Exceptional, (194)
"Nice hotel by the lake"
The price is ₩183,977
₩202,389 total
includes taxes & fees
Oct 12 - Oct 13
Fairfield Inn & Suites Seneca Clemson Univ Area
Hampton Inn & Suites Seneca-Clemson Area
Exterior

Hampton Inn & Suites Seneca-Clemson Area

2.5 star property
9.4 out of 10, Exceptional, (643)
"Great location to downtown Seneca. Very quiet with great workout facility"
The price is ₩175,819
₩193,403 total
includes taxes & fees
Oct 12 - Oct 13
Hampton Inn & Suites Seneca-Clemson Area
Best Western Seneca-Clemson
Lobby

Best Western Seneca-Clemson

2.5 star property
8.4 out of 10, Very Good, (620)
"Convenient for Clemson visits."
The price is ₩127,287
₩140,016 total
includes taxes & fees
Oct 16 - Oct 17
Best Western Seneca-Clemson
Best Western Plus Clemson Hotel & Conference Center
Property amenity

Best Western Plus Clemson Hotel & Conference Center

2.5 star property
8.2 out of 10, Very Good, (1010)
"Great value and great hotel. We would stay there again. "
The price is ₩138,211
₩153,413 total
includes taxes & fees
Oct 12 - Oct 13
Best Western Plus Clemson Hotel & Conference Center
Comfort Inn & Suites Clemson - University Area
Lobby

Comfort Inn & Suites Clemson - University Area

2.5 star property
8.2 out of 10, Very Good, (1002)
"Awesome place to stay"
The price is ₩138,197
₩153,399 total
includes taxes & fees
Oct 16 - Oct 17
Comfort Inn & Suites Clemson - University Area
Days Inn by Wyndham Anderson
Free daily continental breakfast

Days Inn by Wyndham Anderson

2.0 star property
7.6 out of 10, Good, (1010)
"Rooms were clean and staff was very accommodating!"
The price is ₩87,282
₩96,884 total
includes taxes & fees
Oct 12 - Oct 13
Days Inn by Wyndham Anderson
Woodspring Suites Anderson North I-85
Exterior

Woodspring Suites Anderson North I-85

2.5 star property
7.2 out of 10, Good, (34)
"This was a new clean facility with nice staff. "
The price is ₩112,668
₩125,062 total
includes taxes & fees
Oct 11 - Oct 12
Woodspring Suites Anderson North I-85
Inn @ Clemson
Lobby lounge

Inn @ Clemson

2.5 star property
8.0 out of 10, Very Good, (1004)
"Very nice staff and great place to stay"
The price is ₩114,237
₩126,803 total
includes taxes & fees
Oct 12 - Oct 13
Inn @ Clemson
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Reception

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

2.5 star property
9.0 out of 10, Wonderful, (570)
"Good breakfast, clean "
The price is ₩147,182
₩163,369 total
includes taxes & fees
Oct 19 - Oct 20
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Baymont by Wyndham Anderson Clemson
Outdoor pool

Baymont by Wyndham Anderson Clemson

2.5 star property
7.0 out of 10, Good, (820)
"Clean room | Staff | Parking | Family-friendly"
The price is ₩102,685
₩113,980 total
includes taxes & fees
Oct 12 - Oct 13
Baymont by Wyndham Anderson Clemson
Hilton Garden Inn Anderson
Exterior

Hilton Garden Inn Anderson

3.0 star property
9.0 out of 10, Wonderful, (650)
"When I got there to check in the front desk worker was very nice and helpful room was nice and clean "
The price is ₩133,348
₩148,016 total
includes taxes & fees
Oct 20 - Oct 21
Hilton Garden Inn Anderson
Baymont by Wyndham Easley/Greenville
Lobby

Baymont by Wyndham Easley/Greenville

2.5 star property
7.2 out of 10, Good, (709)
"Room is clean. Bed was comfortable."
The price is ₩96,267
₩106,864 total
includes taxes & fees
Oct 11 - Oct 12
Baymont by Wyndham Easley/Greenville
The Shepherd Hotel Downtown Clemson
Superior Room, 2 Queen Beds | In-room safe, blackout drapes, soundproofing, iron/ironing board

The Shepherd Hotel Downtown Clemson

4.0 star property
9.8 out of 10, Exceptional, (699)
"Beautiful hotel. Love their mission! "
The price is ₩269,548
₩299,198 total
includes taxes & fees
Oct 19 - Oct 20
The Shepherd Hotel Downtown Clemson
Microtel Inn & Suites by Wyndham Anderson/Clemson
Lobby

Microtel Inn & Suites by Wyndham Anderson/Clemson

2.0 star property
8.2 out of 10, Very Good, (1002)
"Great stay"
The price is ₩115,164
₩127,832 total
includes taxes & fees
Oct 12 - Oct 13
Microtel Inn & Suites by Wyndham Anderson/Clemson
Quality Inn Clemson near University
Reception

Quality Inn Clemson near University

2.5 star property
7.0 out of 10, Good, (880)
"Shopping is good nears around "
The price is ₩85,713
₩95,141 total
includes taxes & fees
Oct 30 - Oct 31
Quality Inn Clemson near University
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Where to stay in Seneca

Find the best Seneca areas and neighborhoods for the activities you enjoy most.

Downtown

While visiting Downtown, you might make a stop by sights like Seneca Historic District and Oconee County Library Seneca Branch.

Pine Ridge Point

While Pine Ridge Point isn't home to many top sights, Lake Keowee and Keowee Key Golf Course are some notable places to visit nearby.

Indian Oaks

While there might not be top attractions in Indian Oaks, you can explore the larger area and discover places like Keowee Reservoir and Oconee County Library Seneca Branch.

Serenity Bay

Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.

Keowee Plantation

When in Keowee Plantation, you can plan a visit to Keowee Reservoir and Oconee County Library Seneca Branch, some noteworthy sights in the nearby area.

Stay near popular Seneca attractions

High Falls County Park

High Falls County Park is just one of the places to see in Seneca, so why not enjoy the other things to explore during your travels? Stroll along this family-friendly area's lakeside, or simply enjoy its coffeehouses.
See properties

Oconee County Library Seneca Branch

After visiting Oconee County Library Seneca Branch, make a plan to see the other sights and activities in Seneca.
See properties

Learn more about Seneca

Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.

See all hotels in Seneca
View from the dike in Clemson, SC. This trail is used by runners, bikers, and lots of dog walkers.
Photo by Cindy Keese
Open Photo by Cindy Keese

Top Seneca Hotel Reviews

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

10/10 Excellent
"The staff was very accommodating, the decor was beautiful and the room was comfortable. The roof deck was a great spot to relax during the day. It was a little loud at night, especially being on the 2nd floor directly below the bar. But overall it was a great stay."
Kara 1-night trip
Posted 4 days ago
The Shepherd Hotel Downtown Clemson

More cheap stays in Seneca

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

1007 George Smith Mill Rd, Anderson, SC
The price is ₩87,282 per night from Oct 12 to Oct 13
₩87,282
₩96,884 total
Oct 12 - Oct 13
includes taxes & fees
7.4/10 Good! (1,007 reviews)

Frequently asked questions

Where is the best place for a stay in Seneca?
Tru by Hilton Seneca Clemson is ranked highly by Expedia customers. This hotel is a short 5-minute walk from Lake Hartwell, and it offers free breakfast and free parking. Traveler reviews also recommend Lakeside Lodge Clemson and Hampton Inn & Suites Seneca-Clemson Area as top choices for your visit. See all available top hotels, or vacation rentals in Seneca.
If I need to cancel my hotel reservation in Seneca, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.
Where can I learn more about changing or cancelling my trip to Seneca?
To find more details about updating your trip to Seneca or cancelling it, click here.
What's the best place to stay for a family vacation to Seneca?
Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Attractions in the area like Ultimate Action Sports are also fun for the whole family. Find more child-friendly accommodations in Seneca.
What's the best LGBTQ-friendly place to stay in Seneca?
Hampton Inn & Suites Seneca-Clemson Area is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Tru by Hilton Seneca Clemson is another good choice for your stay. See all available hotels listed as LGBTQ-friendly in Seneca.
What's the best pet-friendly accommodation in Seneca?
Lakeside Lodge Clemson is a top hotel for people traveling with their pets, and offers a restaurant and a seasonal outdoor pool for its human guests. Other good choices to stay with your pet include Tru by Hilton Seneca Clemson and Days Inn by Wyndham Seneca / Clemson Area. See more pet-friendly hotel accommodations in Seneca.
What are some hotels with pools in Seneca?
Quality Inn Seneca Clemson Area US-123: Features daily, a seasonal outdoor pool, and free self parking. Lakeside Lodge Clemson and Best Western Seneca-Clemson are two additional hotels with an onsite pool. View all hotels with pools in Seneca.
What is the best accommodation for staying close to Greenville-Spartanburg International Airport (GSP)?
Wyndham Garden Greenville Airport is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and a restaurant. It's located 3.8 mi (6.1 km) from Greenville-Spartanburg Intl. Airport. Other good options near the airport include Best Western Greenville Airport Inn and Extended Stay America - Greenville - Airport.
What is staying in Seneca like?
Visitors to Seneca are sure to enjoy the sporting events, lakeside setting, and university setting. Welcoming and scenic, this city also attracts tourists with its coffeehouses. In Seneca, there are 288 hotels and other accommodations to choose from. Find out more about Seneca.
What should I do while I'm visiting Seneca?
Cultural venues include The Gauntlet and Oconee Community Theatre. Natural beauty is on display at Keowee Reservoir, Lake Keowee, and Lake Hartwell. Exploring the waterfront is a great activity, and Keowee Key Golf Course is one place to visit. Check out what more to see and do in Expedia's Seneca guide.
What's the weather like in Seneca?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Seneca is 62 inches.

Explore a world of travel with Expedia