Find hotels in Seneca, SC from ₩81,147

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Compare 1,605 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Postcard Cabins Lake Hartwell

2.0 star property
9.8 out of 10, Exceptional, (24)
"Lovely stay! Highly recommend!!!"
The price is ₩123,139
₩188,721 total
includes taxes & fees
Aug 26 - Aug 27
Postcard Cabins Lake Hartwell

Lakeside Lodge Clemson

2.5 star property
9.0 out of 10, Wonderful, (999)
"Great place to stay in Clemson"
The price is ₩150,810
₩189,080 total
includes taxes & fees
Aug 28 - Aug 29
Lakeside Lodge Clemson

Fairfield Inn & Suites Seneca Clemson Univ Area

2.5 star property
9.4 out of 10, Exceptional, (186)
"Beautiful clean hotel. Staff was very welcoming. Breakfast area was very clean with many options. The river view is so beautiful. "
The price is ₩178,482
₩196,344 total
includes taxes & fees
Sep 1 - Sep 2
Fairfield Inn & Suites Seneca Clemson Univ Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 star property
9.4 out of 10, Exceptional, (629)
"The staff were very friendly and helpful. The room was clean and the breakfast was great!"
The price is ₩174,276
₩191,704 total
includes taxes & fees
Aug 27 - Aug 28
Hampton Inn & Suites Seneca-Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

2.0 star property
6.8 out of 10, (693)
"The property was near the area that I needed to be in. It has ample shops and restaurants in the area "
The price is ₩98,788
₩108,666 total
includes taxes & fees
Sep 8 - Sep 9
Days Inn by Wyndham Seneca / Clemson Area

Quality Inn Seneca Clemson Area US-123

2.5 star property
8.0 out of 10, Very Good, (632)
"Ok hotel for a quick stay "
The price is ₩110,825
₩135,609 total
includes taxes & fees
Sep 7 - Sep 8
Quality Inn Seneca Clemson Area US-123

Best Western Seneca-Clemson

2.5 star property
8.4 out of 10, Very Good, (601)
"We liked the location. It was easy to explore Lake Keowee from here. The blackout window shades were nice too! The room was so humid that it even made the sheets feel damp. "
The price is ₩139,949
₩153,943 total
includes taxes & fees
Sep 1 - Sep 2
Best Western Seneca-Clemson

Woodspring Suites Anderson North I-85

2.5 star property
6.6 out of 10, (23)
"Very nice and clean property. Staff was so nice and helpful. Made check in so easy"
The price is ₩116,221
₩129,005 total
includes taxes & fees
Aug 26 - Aug 27
Woodspring Suites Anderson North I-85

Inn @ Clemson

2.5 star property
8.0 out of 10, Very Good, (1004)
"This hotel was a great value. The staff was really helpful and friendly"
The price is ₩123,139
₩136,684 total
includes taxes & fees
Sep 1 - Sep 2
Inn @ Clemson

Best Western Plus Clemson Hotel & Conference Center

2.5 star property
8.2 out of 10, Very Good, (1008)
"Great stay!!"
The price is ₩145,829
₩161,870 total
includes taxes & fees
Aug 28 - Aug 29
Best Western Plus Clemson Hotel & Conference Center

Comfort Inn & Suites Clemson - University Area

2.5 star property
8.2 out of 10, Very Good, (1006)
"Awesome place to stay"
The price is ₩139,949
₩155,344 total
includes taxes & fees
Sep 13 - Sep 14
Comfort Inn & Suites Clemson - University Area

Quality Inn Clemson near University

2.5 star property
7.0 out of 10, Good, (863)
"Great customer service "
The price is ₩81,853
₩90,857 total
includes taxes & fees
Sep 1 - Sep 2
Quality Inn Clemson near University

Baymont by Wyndham Anderson Clemson

2.5 star property
7.0 out of 10, Good, (812)
"Excellent stay "
The price is ₩94,083
₩104,432 total
includes taxes & fees
Sep 12 - Sep 13
Baymont by Wyndham Anderson Clemson

Days Inn by Wyndham Anderson

2.0 star property
7.4 out of 10, Good, (1003)
"Great located "
The price is ₩81,147
₩90,073 total
includes taxes & fees
Sep 1 - Sep 2
Days Inn by Wyndham Anderson

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

2.5 star property
9.2 out of 10, Wonderful, (561)
"Clean, convenient, safe. Beds are comfortable. For the rate charged this place offers everything that’s important to me in a hotel stay. Definitely would stay here again. "
The price is ₩142,509
₩158,186 total
includes taxes & fees
Aug 31 - Sep 1
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

The Shepherd Hotel Downtown Clemson

4.0 star property
9.8 out of 10, Exceptional, (667)
"Fantastic high-end hotel with great amenities, service and convenience!"
The price is ₩247,661
₩274,904 total
includes taxes & fees
Sep 1 - Sep 2
The Shepherd Hotel Downtown Clemson

Comfort Suites Anderson-Clemson

2.5 star property
8.4 out of 10, Very Good, (995)
"RESTAURANTS, HOTEL WAS GREAT STAFF WAS AWESOME I WOULD DEFINITELY RECOMMEND. "
The price is ₩154,408
₩171,392 total
includes taxes & fees
Aug 31 - Sep 1
Comfort Suites Anderson-Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson

2.0 star property
8.2 out of 10, Very Good, (1000)
"Great place to stay!"
The price is ₩116,428
₩129,234 total
includes taxes & fees
Sep 1 - Sep 2
Microtel Inn & Suites by Wyndham Anderson/Clemson

Country Inn & Suites by Radisson, Anderson, SC

2.5 star property
8.4 out of 10, Very Good, (1001)
"It was a good place to stay good people "
The price is ₩150,976
₩167,585 total
includes taxes & fees
Sep 2 - Sep 3
Country Inn & Suites by Radisson, Anderson, SC

Holiday Inn Express & Suites Clemson by IHG

2.5 star property
8.8 out of 10, Excellent, (929)
"It was a very easy and convenient place to stay"
The price is ₩169,558
₩188,208 total
includes taxes & fees
Sep 1 - Sep 2
Holiday Inn Express & Suites Clemson by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Check out hotels with free breakfast in Seneca

Hotels with a pool in Seneca you'll enjoy

These pet-friendly hotels in Seneca may fit your trip

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Seneca

Find the best Seneca areas and neighborhoods for the activities you enjoy most.

Downtown

2 out of top 10 points of interest in this area

Downtown Seneca captures the essence of small-town Southern charm with its well-preserved railroad heritage and historic brick buildings. Tree-lined streets lead to charming shops and local eateries housed in structures dating back to the 1800s. Ram Cat Alley's colorful murals tell stories of local history while the old courthouse square hosts community gatherings. This walkable district offers a peaceful retreat from big city life. Visitors can browse antique stores for railroad memorabilia, sample authentic Southern comfort food, or explore the cultural exhibits at the Bertha Lee Strickland Museum. The nearby Lake Keowee provides outdoor recreation just minutes away.

Serenity Bay

Serenity Bay offers a peaceful retreat within Saxony Forest's coastal embrace. The quiet residential streets wind through mature trees, creating a tranquil atmosphere away from tourist crowds. Nature lovers can explore nearby Lake Keowee or enjoy the neighborhood's forest trails. The area perfectly balances woodland serenity with beach proximity. Visitors should plan for self-contained vacation rentals rather than hotels. While dining options are limited within the neighborhood, the natural surroundings provide ideal conditions for relaxation and outdoor recreation.

Pine Ridge Point

Lake Keowee's serene waters lap against the shores of Pine Ridge Point, a tranquil residential haven in Seneca. Private docks stretch into crystal-clear waters where boats gently bob. Towering pines create natural privacy between lakefront homes. Visitors enjoy peaceful mornings watching mist rise over the water. This neighborhood offers an authentic lakeside living experience without tourist crowds. Vacation rentals range from cozy cabins to luxury estates with private boat slips. Days revolve around swimming, fishing, and water sports on Lake Keowee. Nature trails wind through mature forests for hiking and birdwatching.

Indian Oaks

Indian Oaks offers a tranquil retreat in suburban Seneca where mature oak trees create natural canopies over peaceful residential streets. This family-oriented community provides an authentic glimpse into American suburban living without tourist crowds. Landscaped yards and community green spaces showcase South Carolina's native beauty. Visitors can enjoy quiet morning walks on spacious sidewalks while listening to birdsong. Lake Keowee lies just beyond the neighborhood boundaries for those seeking water activities. With minimal commercial presence, Indian Oaks delivers a genuinely restful experience away from urban bustle.

Learn more about Seneca

Escape to Seneca! Enjoy its sports, lake views, and university life.

View from the dike in Clemson, SC. This trail is used by runners, bikers, and lots of dog walkers.
Photo by Cindy Keese
Open Photo by Cindy Keese

Top Seneca Hotel Reviews

Frequently asked questions

Where is the best place for a stay in Seneca?

Tru by Hilton Seneca Clemson is ranked highly by Expedia customers. This hotel is a short 5-minute walk from Lake Hartwell, and it offers free breakfast and free parking. Traveler reviews also recommend Lakeside Lodge Clemson and Hampton Inn & Suites Seneca-Clemson Area as top choices for your visit. See all available top hotels, or vacation rentals in Seneca.

If I need to cancel my hotel reservation in Seneca, will I receive a refund?

Yes, the majority of hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.

Where can I learn more about changing or cancelling my trip to Seneca?

To find more details about updating your trip to Seneca or cancelling it, click here.

What's the best place to stay for a family vacation to Seneca?

Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Attractions in the area like Ultimate Action Sports are also fun for the whole family. Find more child-friendly accommodations in Seneca.

What's the best LGBTQ-friendly place to stay in Seneca?

Hampton Inn & Suites Seneca-Clemson Area is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Tru by Hilton Seneca Clemson is another good choice for your stay. See all available hotels listed as LGBTQ-friendly in Seneca.

What's the best pet-friendly accommodation in Seneca?

Lakeside Lodge Clemson is a top hotel for people traveling with their pets, and offers a restaurant and a seasonal outdoor pool for its human guests. Other good choices to stay with your pet include Tru by Hilton Seneca Clemson and Days Inn by Wyndham Seneca / Clemson Area. See more pet-friendly hotel accommodations in Seneca.

What are some hotels with pools in Seneca?

Lakeside Lodge Clemson: Hotel, 7-minute walk from Lake Hartwell. Features free self parking, a seasonal outdoor pool, and complimentary wireless internet access. Fairfield Inn & Suites Seneca Clemson Univ Area and Hampton Inn & Suites Seneca-Clemson Area are two additional hotels with an onsite pool. View all hotels with pools in Seneca.

What is the best accommodation for staying close to Greenville-Spartanburg International Airport (GSP)?

Wyndham Garden Greenville Airport is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and a restaurant. It's located 3.8 mi (6.1 km) from Greenville-Spartanburg Intl. Airport. Other good options near the airport include Best Western Greenville Airport Inn and Extended Stay America - Greenville - Airport.

What is staying in Seneca like?

Visitors to Seneca are sure to enjoy the sporting events, lakeside setting, and university setting. Welcoming and scenic, this city also attracts tourists with its coffeehouses. In Seneca, there are 287 hotels and other accommodations to choose from. Find out more about Seneca.

What should I do while I'm visiting Seneca?

Cultural venues include The Gauntlet and Oconee Community Theatre. Natural beauty is on display at Keowee Reservoir, Lake Keowee, and Lake Hartwell. Exploring the waterfront is a great activity, and Keowee Key Golf Course is one place to visit. Check out what more to see and do in Expedia's Seneca guide.

What's the weather like in Seneca?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Seneca is 62 inches.