Find hotels in South Grand, St. Louis

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 29 - Dec 30
Tomorrow
Dec 30 - Dec 31
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Filter by

Guest rating
Guest rating
Star rating

Our top choices for South Grand hotels

Exterior
Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis, 6.3 km from South Grand
8.8 out of 10, Excellent, (1020)
"Staff were real nice. Accommodating. "
United States
Tim
The price is ₩154,546
₩182,255 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hilton Pennywell St. Louis at the Arch
Lobby
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 6.3 km from South Grand
8.4 out of 10, Very Good, (4041)
"Staff was supper nice and it all went so smooth."
United States
Brayden
The price is ₩142,724
₩168,312 total
includes taxes & fees
Dec 30 - Dec 31
Hyatt Regency St. Louis at The Arch
Lobby
Drury Inn & Suites St. Louis Collinsville

Drury Inn & Suites St. Louis Collinsville

Drury Inn & Suites St. Louis Collinsville
3.0 star property
22.9 km from South Grand
9.6 out of 10, Exceptional, (1003)
"Nice to have food and drinks provided "
United States
MICHAEL
The price is ₩141,268
₩162,432 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Drury Inn & Suites St. Louis Collinsville
Exterior
Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis, 6.3 km from South Grand
8.8 out of 10, Excellent, (1258)
"Very cool hotel, rooms were clean and nice design, the food at the bar/restaurant was fantastic!!!"
United States
Cullin
The price is ₩158,410
₩188,395 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Embassy Suites by Hilton St. Louis Downtown
Indoor pool, open 6:00 AM to 10:00 PM, sun loungers
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
2.5 star property
Downtown St. Louis, 6.6 km from South Grand
8.8 out of 10, Excellent, (1195)
"The staff was probably the best part of the stay. "
United States
Ja Nelle
The price is ₩140,677
₩164,491 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Breakfast, lunch and dinner served
Live by Loews - St.Louis

Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis, 5.7 km from South Grand
9.4 out of 10, Exceptional, (1105)
"Clean room, great restaurant and bar down stairs "
United States
Ambria
The price is ₩214,807
₩255,467 total
includes taxes & fees
Dec 30 - Dec 31
Live by Loews - St.Louis
Rooftop terrace
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 6.2 km from South Grand
9.4 out of 10, Exceptional, (3286)
"The room was great , the staff was awesome breakfast and evening drinks and food were great overall it was an excellent stay "
United States
Daniel
The price is ₩207,585
₩242,727 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Drury Plaza Hotel St. Louis at the Arch
Lobby sitting area
Missouri Athletic Club

Missouri Athletic Club

Missouri Athletic Club
3.5 star property
Downtown St. Louis, 6.5 km from South Grand
8.8 out of 10, Excellent, (1000)
"The room was nice and the staff was excellent."
United States
Annette
The price is ₩243,641
₩284,886 total
includes taxes & fees
Dec 30 - Dec 31
Missouri Athletic Club
Casino
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
27.5 km from South Grand
8.4 out of 10, Very Good, (1010)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is ₩258,201
₩325,699 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Ameristar Casino Resort and Spa
Exterior
Holiday Inn Express & Suites - O'Fallon /Shiloh by IHG

Holiday Inn Express & Suites - O'Fallon /Shiloh by IHG

Holiday Inn Express & Suites - O'Fallon /Shiloh by IHG
2.5 star property
28.8 km from South Grand
8.4 out of 10, Very Good, (556)
"Smooth check-in, decent place to spend night."
United States
Jacob
The price is ₩147,049
₩163,195 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Holiday Inn Express & Suites - O'Fallon /Shiloh by IHG
Restaurant
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL
3.0 star property
28.1 km from South Grand
9.6 out of 10, Exceptional, (1006)
"Excellent location, clean and spacious room, great morning breakfast with numerous choices and of course helpful and pleasant staff."
United States
David
The price is ₩152,802
₩177,224 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Drury Inn & Suites St. Louis O'Fallon, IL
Pub
The Knight Center at Washington University

The Knight Center at Washington University

The Knight Center at Washington University
2.5 star property
7.6 km from South Grand
9.4 out of 10, Exceptional, (453)
"Great place to stay, friendly staff, nice room, bathroom, and TV. "
United States
Natalie
The price is ₩193,326
₩222,301 total
includes taxes & fees
Jan 1 - Jan 2, 2026
The Knight Center at Washington University
Terrace/patio
Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
7.7 km from South Grand
9.4 out of 10, Exceptional, (842)
"Clean, would stay again."
United States
Eryka
The price is ₩145,824
₩178,898 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Courtyard by Marriott St. Louis Brentwood
Lobby
Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
28.8 km from South Grand
8.8 out of 10, Excellent, (1010)
"Breakfast was excellent along with clean comfortable beds. "
United States
Scott
The price is ₩176,142
₩202,434 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Embassy Suites by Hilton St. Louis St. Charles
BBQ/picnic area
Hampton Inn St. Louis/Chesterfield

Hampton Inn St. Louis/Chesterfield

Hampton Inn St. Louis/Chesterfield
3.5 star property
27.4 km from South Grand
8.6 out of 10, Excellent, (1002)
"Clean room, comfy bed & friendly staff!!"
United States
Carole
The price is ₩124,127
₩143,973 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Hampton Inn St. Louis/Chesterfield
Lobby
Tru by Hilton St. Charles St. Louis, MO

Tru by Hilton St. Charles St. Louis, MO

Tru by Hilton St. Charles St. Louis, MO
2.5 star property
27.9 km from South Grand
8.6 out of 10, Excellent, (775)
"Room was wonderful great location"
United States
Sandra
The price is ₩152,499
₩176,788 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Tru by Hilton St. Charles St. Louis, MO
Reception
La Quinta Inn & Suites by Wyndham St Louis Route 66

La Quinta Inn & Suites by Wyndham St Louis Route 66

La Quinta Inn & Suites by Wyndham St Louis Route 66
3.0 star property
14.3 km from South Grand
8.0 out of 10, Very Good, (1000)
"Nice Staff, Clean Rooms, Good Area!!"
United States
Keyaira
The price is ₩138,471
₩160,956 total
includes taxes & fees
Jan 5 - Jan 6, 2026
La Quinta Inn & Suites by Wyndham St Louis Route 66
Breakfast, lunch, dinner served; American cuisine
Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield
3.0 star property
27.4 km from South Grand
9.6 out of 10, Exceptional, (1001)
"Wonderful staff, easy parking, nice breakfast, very comfortable room."
United States
Carole
The price is ₩177,324
₩205,674 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Hyatt Place St. Louis/Chesterfield
Interior
21C Museum Hotel St Louis

21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West, 5.5 km from South Grand
9.0 out of 10, Wonderful, (1515)
"Hotel was comfortable, clean and unique. All staff was wonderful "
United States
Sharon
The price is ₩206,302
₩248,435 total
includes taxes & fees
Jan 4 - Jan 5, 2026
21C Museum Hotel St Louis
Terrace/patio
The West End

The West End

The West End
2.0 star property
Central West End, 4.5 km from South Grand
8.4 out of 10, Very Good, (410)
"Great stay!"
United States
Shaniqua
The price is ₩121,558
₩169,528 total
includes taxes & fees
Jan 7 - Jan 8, 2026
The West End
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in South Grand

Find the best South Grand areas and neighborhoods for the activities you enjoy most.
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Busch Stadium or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Berkeley

Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Top South Grand Hotel Reviews

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

10/10 Excellent
"Everything was great."
Doreen 1-night trip
Posted 1 day ago
Hyatt Regency St. Louis at The Arch

Frequently asked questions

What's it like in South Grand?
Travelers to the South Grand neighborhood in St. Louis will be sure to enjoy their stay.
How many hotels can I expect to find in South Grand?
If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 23 South Grand hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in South Grand, will I receive a refund?
Yes! The majority of hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals in South Grand.
Where can I learn more about changing or cancelling my trip to South Grand?
For more information about picking new dates or cancelling your trip to South Grand, click here.
What are the top things to see and do in South Grand?
A few places to visit in the area around South Grand include Tower Grove Tennis Center, Missouri Botanical Gardens and Arboretum, and George Washington Carver Garden. When you're sightseeing in St. Louis, Cherokee Street and Miniature Museum of Greater St. Louis are also worth a stop.