A paved courtyard with a brick pathway, trees, and a distant view of a road and buildings.

Find Resorts & Hotels with Spas in Southeast Iowa

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southeast Iowa Resorts & Hotels with Spas

Tonight
Oct 9 - Oct 10
Tomorrow
Oct 10 - Oct 11
This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18
No exact matches found, but these alternatives could be just right

Recommended hotels in Southeast Iowa

A lobby with a stone fireplace, comfortable seating, and a flat-screen TV mounted on the wall.
A fire pit surrounded by outdoor furniture, including a sofa and chairs, in a patio area.
A hotel room with two beds, a television, a desk with a lamp, and a chair.
A reception area with a reception desk, a plant, and a sign for Boulders Inn & Suites.

1. Cobblestone Inn & Suites - Fort Madison

Cobblestone Inn & Suites - Fort Madison
Fort Madison
₩127,287
₩142,563 total
includes taxes & fees
Oct 11 - Oct 12
Cobblestone Inn & Suites - Fort Madison
A spacious living room with a large sofa, two armchairs, a coffee table, and a fireplace.
A modern kitchen with a granite countertop, wooden chairs, and a large painting of a colorful horse.
A cozy living room with a grey sofa, two patterned armchairs, a wooden coffee table, and a brick accent wall.
An indoor swimming pool with wooden walls and a balcony.

2. AmericInn by Wyndham Mount Pleasant

AmericInn by Wyndham Mount Pleasant
Mount Pleasant
₩101,537
₩113,722 total
includes taxes & fees
Nov 8 - Nov 9
AmericInn by Wyndham Mount Pleasant
A hotel room with a bed, a sofa, a small table, a chair, a nightstand, and a painting on the wall.
A bathroom with a granite countertop sink, a mirror, a toilet, a shower with a beige curtain, and a marble wall.
A modern reception area with a dark granite counter, light-colored walls, and a seating area with a sofa and chairs.
A living room with a sofa, two armchairs, a coffee table with a plant, a lamp, and a TV on the wall.

3. Best Western Mt. Pleasant Inn

Best Western Mt. Pleasant Inn
Mount Pleasant
₩104,571
₩117,120 total
includes taxes & fees
Oct 18 - Oct 19
Best Western Mt. Pleasant Inn
A spacious living area with a wooden staircase, a stone fireplace, and a reception desk.
A hotel room with two beds, a large window, a standing lamp, and a patterned carpet.
A hotel room with a bed, a desk, a sofa, a lamp, and a mirror.
An indoor swimming pool with clear water, surrounded by a white fence, and equipped with multiple entry points and seating areas.

4. Quality Inn & Suites Fort Madison near Hwy 61

Quality Inn & Suites Fort Madison near Hwy 61
Fort Madison
₩112,409
₩125,898 total
includes taxes & fees
Nov 1 - Nov 2
Quality Inn & Suites Fort Madison near Hwy 61
A guest registration area with a counter, informational signs, and various items on shelves.
A bathroom with a toilet, a shower, and a bathtub.
An indoor swimming pool with a wooden ceiling and walls, a bench, and a rack of towels.
A brick building with a sign for Nauvoo Family Inn & Suites, featuring a traditional design with a tower and arched windows.

5. The Inn at Old Nauvoo

The Inn at Old Nauvoo
Nauvoo
₩164,151
₩185,452 total
includes taxes & fees
Nov 1 - Nov 2
The Inn at Old Nauvoo
A hotel room with two beds, a desk, a chair, and a large window.
A small, clean room with a kitchenette, a coffee machine, a microwave, and a TV mounted on the wall. There are two tables and chairs, and a window providing natural light.
A bathroom with a bathtub, toilet, and sink.
A reception area with a white sofa, a potted plant, and a framed picture on the wall.

6. Super 8 by Wyndham Mt Pleasant

Super 8 by Wyndham Mt Pleasant
Mount Pleasant
₩93,954
₩105,228 total
includes taxes & fees
Nov 8 - Nov 9
Super 8 by Wyndham Mt Pleasant
An indoor swimming pool with a wooden ceiling, grey tiled floor, and several lounge chairs and tables around the pool area.
A hotel room with a large bed, a desk with a computer, a chair, a window with curtains, and a view of the city.
A spa area with a hot tub, wooden ceiling, and tiled walls.
A modern hotel lobby with blue and pink seating, a central coffee table, and a kitchen area in the background.

7. Quality Inn & Suites Keokuk North

Quality Inn & Suites Keokuk North
Keokuk
₩123,563
₩138,390 total
includes taxes & fees
Nov 1 - Nov 2
Quality Inn & Suites Keokuk North
A patio area with Adirondack chairs and a central fire pit.
An indoor swimming pool with clear water, surrounded by chairs and tables, and a view of the outside through large windows.
A hotel room with a bed, a desk, a chair, and a TV.
A spacious dining area with multiple tables and chairs, a television on a shelf, and a large chandelier.

8. Hampton Inn & Suites Burlington

Hampton Inn & Suites Burlington
Burlington
₩164,475
₩195,995 total
includes taxes & fees
Oct 22 - Oct 23
Hampton Inn & Suites Burlington
A room with a large window, a sofa, and a chair.
A staircase with red carpeted steps leading to a landing with white doors and a red EXIT sign.
A brick building with a balcony, a staircase, and a sign reading "Zions Mercantile".
A bedroom with two beds, a ceiling fan, a TV, and a dresser.

9. Nauvoo Temple House Hotel

Nauvoo Temple House Hotel
Nauvoo
₩132,503
₩155,688 total
includes taxes & fees
Oct 31 - Nov 1
Nauvoo Temple House Hotel
A row of single-family homes with a well-maintained lawn and a tree in the foreground.
A living room with a sofa, a patterned armchair, a dining table with chairs, a kitchen area with wooden cabinets and a refrigerator, and a television on a stand.
A compact kitchen with wooden cabinets, a microwave, a coffee maker, and a dishwasher.
A bedroom with a large bed, a bedside table with a lamp, a window with blinds, and a framed picture on the wall.

10. Nauvoo Vacation Villas & Condos

Nauvoo Vacation Villas & Condos
Nauvoo
₩192,960
₩204,497 total
includes taxes & fees
Oct 15 - Oct 16
Nauvoo Vacation Villas & Condos
View all properties

Choose what matters most at spa hotels in Southeast Iowa

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Southeast Iowa Hotel Reviews

Best Western Mt. Pleasant Inn

Best Western Mt. Pleasant Inn

8/10 Good
"We enjoyed our stay. Only complaint was that the room smelled musty. Thank you"
Jeffrey 2-night trip
Posted less than an hour ago
Best Western Mt. Pleasant Inn
Quality Inn & Suites Keokuk North

Quality Inn & Suites Keokuk North

8/10 Good
"The Staff, both check in and then Mary during breakfast was so awesome! You will be well treated there!"
Carl 1-night trip
Posted 15 hours ago
Quality Inn & Suites Keokuk North
Quality Inn & Suites Mount Pleasant

Quality Inn & Suites Mount Pleasant

10/10 Excellent
"Good stay for the price. Clean and comfortable room."
William 1-night trip
Posted 22 hours ago
Quality Inn & Suites Mount Pleasant
AmericInn by Wyndham West Burlington

AmericInn by Wyndham West Burlington

10/10 Excellent
"Very comfortable. Price was right. Location was great for on/off highway. Finding good dining was away from lodging."
Daniel V 1-night trip
Posted 2 days ago
AmericInn by Wyndham West Burlington

Explore a world of travel with Expedia