A forested valley with autumn foliage, a rocky cliff, and a sunset.

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Check availability on Southern Illinois Resorts & Hotels with Spas

Next weekend
Nov 13 - Nov 15
In two weeks
Nov 20 - Nov 22

Our top choices for Southern Illinois hotels with a spa

A hotel lobby with a Kitchen+Bar area, seating arrangements, and a view to the outside.

1. Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
3.5 star property
Mount Vernon
9.8 out of 10, Exceptional, (1,868 reviews)
"Nice comfortable stay"
United States
Mei
The price is ₩151,534
₩170,903 total
includes taxes & fees
Nov 15 - Nov 16
Drury Plaza Hotel Mt. Vernon
A hotel with a covered entrance, stone pillars, and a modern design.

2. Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG
2.5 star property
Mount Vernon
8.8 out of 10, Excellent, (1,004 reviews)
"Great spacious room. Breakfast was awesome and the helper was outstanding! Great food and coffee."
United States
Doug
The price is ₩151,547
₩170,918 total
includes taxes & fees
Dec 10 - Dec 11
Holiday Inn Express & Suites Mount Vernon by IHG
A hotel lobby with a reception desk, seating area, and a large screen TV.

3. Comfort Suites Mount Vernon

Comfort Suites Mount Vernon
2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1,092 reviews)
"Great bathroom"
United States
Bruce and Robin
The price is ₩160,565
₩180,926 total
includes taxes & fees
Nov 15 - Nov 16
Comfort Suites Mount Vernon
A hotel lobby with a large sofa, armchairs, a Christmas tree, and a patterned carpet.

4. Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
3.0 star property
Mount Vernon
8.8 out of 10, Excellent, (732 reviews)
"Beautiful property very clean when you enter the lobby is very impressive in the staff was very helpful. Our room was clean in the morning. Breakfast was great."
United States
Susan
The price is ₩148,817
₩167,888 total
includes taxes & fees
Nov 12 - Nov 13
Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
A multi-story hotel with a central entrance, illuminated by exterior lights, and a clear sky in the background.

5. Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites
2.5 star property
Centralia
9.6 out of 10, Exceptional, (689 reviews)
"We stayed here with 2 adults and 3 kids and it was perfect. We highly recommend staying here"
United States
Jeremy
The price is ₩189,775
₩212,507 total
includes taxes & fees
Nov 10 - Nov 11
Best Western Plus Centralia Hotel & Suites
A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

6. Super 8 by Wyndham Mt. Vernon IL

Super 8 by Wyndham Mt. Vernon IL
2.5 star property
Mount Vernon
8.0 out of 10, Very good, (1,008 reviews)
"Everything was clean, nice hotel"
United States
Leslie
The price is ₩99,666
₩113,340 total
includes taxes & fees
Nov 15 - Nov 16
Super 8 by Wyndham Mt. Vernon IL
A modern kitchen with wooden cabinets, a refrigerator, a coffee machine, and a microwave. There are red chairs and a table in the dining area.

7. Quality Inn Mount Vernon, IL

Quality Inn Mount Vernon, IL
2.5 star property
Mount Vernon
7.8 out of 10, Good, (724 reviews)
"Clean rooms, complimentary breakfast, great value."
United States
Ryan
The price is ₩98,301
₩111,825 total
includes taxes & fees
Nov 15 - Nov 16
Quality Inn Mount Vernon, IL
An indoor swimming pool with a view of the outside, a hot tub, and a seating area with tables and chairs.

8. DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon
4.0 star property
Mount Vernon
8.4 out of 10, Very good, (910 reviews)
"Loved the onsite bar and the location of the hotel"
United States
Tammi
The price is ₩174,593
₩196,494 total
includes taxes & fees
Nov 12 - Nov 13
DoubleTree by Hilton Mt. Vernon
A spacious lobby with a stone fireplace, a seating area with a sofa and chairs, and a television mounted on the wall.

9. SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
2.5 star property
Whittington
8.8 out of 10, Excellent, (1,003 reviews)
"Very clean and everything was perfect!"
United States
Tad
The price is ₩104,431
₩115,898 total
includes taxes & fees
Dec 1 - Dec 2
SureStay Hotel by Best Western Whittington Rend Lake
A cozy living room with a stone fireplace, leather sofas, and a flat-screen TV.

10. Cobblestone Inn & Suites - Altamont

Cobblestone Inn & Suites - Altamont
2.5 star property
Altamont
9.6 out of 10, Exceptional, (965 reviews)
"Clean and quiet room. Very relaxing after a long day of driving. Highly recommend."
United States
Dee
The price is ₩147,438
₩159,207 total
includes taxes & fees
Nov 10 - Nov 11
Cobblestone Inn & Suites - Altamont
A spacious lobby with a beige sectional sofa, a fireplace, and a view of the outside through large glass doors.

11. Hampton Inn & Suites Effingham

Hampton Inn & Suites Effingham
2.5 star property
Effingham
9.6 out of 10, Exceptional, (803 reviews)
"The property was very clean even just staying a quick overnight traveling the room felt very comfortable."
United States
Scott
The price is ₩162,470
₩180,310 total
includes taxes & fees
Nov 23 - Nov 24
Hampton Inn & Suites Effingham
An outdoor patio area with wicker furniture, a stone pillar, and a glass-enclosed dining area.

12. Holiday Inn Express & Suites Salem by IHG

Holiday Inn Express & Suites Salem by IHG
2.5 star property
Salem
9.4 out of 10, Exceptional, (810 reviews)
"Nice place"
United States
Kim
The price is ₩143,355
₩160,558 total
includes taxes & fees
Nov 15 - Nov 16
Holiday Inn Express & Suites Salem by IHG
A La Quinta hotel with a stone facade, a covered entrance, and a parking lot.

13. La Quinta Inn & Suites by Wyndham Effingham

La Quinta Inn & Suites by Wyndham Effingham
3.0 star property
Effingham
9.2 out of 10, Wonderful, (1,003 reviews)
"Very nice stay!!!"
United States
Steve
The price is ₩150,865
₩168,937 total
includes taxes & fees
Nov 15 - Nov 16
La Quinta Inn & Suites by Wyndham Effingham
A hotel room with a large bed, a desk, a chair, a TV, and a sofa.

14. Best Western Flora Inn

Best Western Flora Inn
2.5 star property
Flora
8.2 out of 10, Very good, (339 reviews)
"The staff and room were both great!"
United States
Terri
The price is ₩122,821
₩133,850 total
includes taxes & fees
Nov 11 - Nov 12
Best Western Flora Inn
An outdoor seating area with a fire pit, surrounded by wooden chairs and a view of a sunset over a landscaped garden.

15. Best Western Plus Parkside Inn & Suites

Best Western Plus Parkside Inn & Suites
2.5 star property
Olney
9.8 out of 10, Exceptional, (397 reviews)
"Very clean and friendly staff."
United States
Lynda
The price is ₩172,914
₩191,900 total
includes taxes & fees
Nov 15 - Nov 16
Best Western Plus Parkside Inn & Suites
A hotel room with a bed, a desk with a chair, a sofa, and a small table.

16. Quality Inn & Suites Vandalia near I-70 and Hwy 51

Quality Inn & Suites Vandalia near I-70 and Hwy 51
2.5 star property
Vandalia
8.2 out of 10, Very good, (1,002 reviews)
"It is an older property but I thought it was very nice"
United States
Colleen
The price is ₩98,301
₩107,128 total
includes taxes & fees
Nov 17 - Nov 18
Quality Inn & Suites Vandalia near I-70 and Hwy 51
An outdoor patio area with a fire pit, seating, and a covered section.

17. Home2 Suites By Hilton Effingham

Home2 Suites By Hilton Effingham
3.0 star property
Effingham
9.6 out of 10, Exceptional, (67 reviews)
"The hotel was clean and room was fantastic in every way."
United States
Steve
The price is ₩174,375
₩195,266 total
includes taxes & fees
Dec 9 - Dec 10
Home2 Suites By Hilton Effingham
A small, clean room with a microwave, a vending machine, and a table with chairs.

18. Rodeway Inn Mount Vernon, IL

Rodeway Inn Mount Vernon, IL
2.0 star property
Mount Vernon
7.2 out of 10, Good, (1,001 reviews)
"Good place to stay, we were traveling and the price was great, clean room, great staff we were very comfortable"
United States
Karalee
The price is ₩89,358
₩101,901 total
includes taxes & fees
Nov 29 - Nov 30
Rodeway Inn Mount Vernon, IL
An indoor swimming pool with a diving board, a changing room, and a tiled floor.

19. Days Inn by Wyndham Mount Vernon

Days Inn by Wyndham Mount Vernon
2.0 star property
Mount Vernon
6.6 out of 10, (1,001 reviews)
"Checking in was very easy and quick. I have no complaints."
United States
Howard
The price is ₩83,556
₩95,461 total
includes taxes & fees
Nov 15 - Nov 16
Days Inn by Wyndham Mount Vernon
A hotel with a covered entrance, a sign indicating it is now open, and a sign for the Cobblestone Hotel & Suites.

20. Cobblestone Hotel & Suites - Newton

Cobblestone Hotel & Suites - Newton
2.5 star property
Newton
9.2 out of 10, Wonderful, (365 reviews)
"Just an overall good place to crash after fishing Newton Lake all day"
United States
Thomas
The price is ₩159,725
₩177,269 total
includes taxes & fees
Nov 10 - Nov 11
Cobblestone Hotel & Suites - Newton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Southern Illinois

Pool
Breakfast included

Top Southern Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"Quiet clean rooms. Excellent breakfast before hitting the road!"
Steven 1-night trip
Posted 2 hours ago
Drury Plaza Hotel Mt. Vernon