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Discover 1,750 Southhampton hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Pear Tree Inn St. Louis Airport
Lobby

Pear Tree Inn St. Louis Airport

2.5 star property
9.4 out of 10, Exceptional, (2670)
"Great place to stay!"
The price is ₩124,985
₩147,138 total
includes taxes & fees
Aug 21 - Aug 22
Pear Tree Inn St. Louis Airport
Pear Tree Inn St. Louis Arnold
Lobby

Pear Tree Inn St. Louis Arnold

2.5 star property
9.2 out of 10, Wonderful, (1001)
"Location is excellent "
The price is ₩124,985
₩144,471 total
includes taxes & fees
Aug 21 - Aug 22
Pear Tree Inn St. Louis Arnold
Drury Plaza Hotel St. Louis Chesterfield
Exterior

Drury Plaza Hotel St. Louis Chesterfield

3.0 star property
9.6 out of 10, Exceptional, (1008)
"Hotel was great "
The price is ₩180,541
₩209,402 total
includes taxes & fees
Aug 21 - Aug 22
Drury Plaza Hotel St. Louis Chesterfield
Hyatt Regency St. Louis at The Arch
Lobby

Hyatt Regency St. Louis at The Arch

4.0 star property
8.4 out of 10, Very Good, (3963)
"Perfect hotel great staff "
The price is ₩165,277
₩194,909 total
includes taxes & fees
Aug 22 - Aug 23
Hyatt Regency St. Louis at The Arch
The Knight Center at Washington University
Pub

The Knight Center at Washington University

2.5 star property
9.4 out of 10, Exceptional, (375)
"Great location and staff!"
The price is ₩175,902
₩202,266 total
includes taxes & fees
Aug 31 - Sep 1
The Knight Center at Washington University
Moonrise Hotel
Exterior

Moonrise Hotel

4.0 star property
9.0 out of 10, Wonderful, (1845)
"Great staff, comfy room!"
The price is ₩178,192
₩211,923 total
includes taxes & fees
Aug 24 - Aug 25
Moonrise Hotel
The Principal Hotel
Exterior

The Principal Hotel

3.5 star property
9.8 out of 10, Exceptional, (118)
"Perfect stay! "
The price is ₩130,569
₩144,902 total
includes taxes & fees
Sep 16 - Sep 17
The Principal Hotel
Drury Inn & Suites St. Louis Collinsville
Lobby

Drury Inn & Suites St. Louis Collinsville

3.0 star property
9.6 out of 10, Exceptional, (1004)
"Great place to stay "
The price is ₩147,207
₩169,262 total
includes taxes & fees
Aug 21 - Aug 22
Drury Inn & Suites St. Louis Collinsville
Wingate by Wyndham St. Louis Airport
Room, 2 Queen Beds, Accessible, Non Smoking (Mobility, Tub W/Grab Bars) | Desk, laptop workspace, iron/ironing board, free cribs/infant beds

Wingate by Wyndham St. Louis Airport

2.5 star property
9.4 out of 10, Exceptional, (1389)
"easy location and parking!"
The price is ₩152,777
₩179,878 total
includes taxes & fees
Sep 2 - Sep 3
Wingate by Wyndham St. Louis Airport
Drury Inn & Suites St. Louis Airport
Lobby

Drury Inn & Suites St. Louis Airport

3.0 star property
9.2 out of 10, Wonderful, (1026)
"Wonderful place to stay very close to the airport! "
The price is ₩154,152
₩180,874 total
includes taxes & fees
Aug 21 - Aug 22
Drury Inn & Suites St. Louis Airport
Clayton Plaza Hotel & Extended Stay
Exterior

Clayton Plaza Hotel & Extended Stay

3.5 star property
8.8 out of 10, Excellent, (2909)
"Wonderful experience once again, the food at breakfast was Amazing "
The price is ₩151,735
₩176,754 total
includes taxes & fees
Aug 31 - Sep 1
Clayton Plaza Hotel & Extended Stay
Best Western Plus St. Louis Airport Hotel
Exterior

Best Western Plus St. Louis Airport Hotel

2.5 star property
9.2 out of 10, Wonderful, (1003)
"Very nice hotel, great informative staff, delicious breakfast options and clean rooms and pool. "
The price is ₩140,485
₩174,282 total
includes taxes & fees
Sep 7 - Sep 8
Best Western Plus St. Louis Airport Hotel
River City Casino & Hotel
Daily cooked-to-order breakfast for a fee

River City Casino & Hotel

4.0 star property
9.0 out of 10, Wonderful, (1323)
"It was very nice there we would definitely stay again "
The price is ₩124,985
₩165,638 total
includes taxes & fees
Aug 24 - Aug 25
River City Casino & Hotel
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Lobby sitting area

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3.0 star property
8.4 out of 10, Very Good, (1004)
"Very good hotel for the price"
The price is ₩123,957
₩143,156 total
includes taxes & fees
Aug 31 - Sep 1
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Courtyard by Marriott St. Louis Brentwood
Terrace/patio

Courtyard by Marriott St. Louis Brentwood

3.0 star property
9.4 out of 10, Exceptional, (782)
"Great place to stay."
The price is ₩164,096
₩193,204 total
includes taxes & fees
Aug 31 - Sep 1
Courtyard by Marriott St. Louis Brentwood
Drury Plaza Hotel St. Louis at the Arch
Rooftop terrace

Drury Plaza Hotel St. Louis at the Arch

3.0 star property
9.4 out of 10, Exceptional, (2958)
"Great place to stay! "
The price is ₩188,874
₩220,849 total
includes taxes & fees
Sep 2 - Sep 3
Drury Plaza Hotel St. Louis at the Arch
The Cheshire
Terrace/patio

The Cheshire

4.0 star property
8.6 out of 10, Excellent, (1005)
"Great place to stay!"
The price is ₩190,124
₩225,749 total
includes taxes & fees
Sep 1 - Sep 2
The Cheshire
21C Museum Hotel St Louis
Exterior

21C Museum Hotel St Louis

4.5 star property
9.0 out of 10, Wonderful, (1302)
"Fun place to stay. Museum on the 2nd floor was so much fun."
The price is ₩211,318
₩254,053 total
includes taxes & fees
Aug 31 - Sep 1
21C Museum Hotel St Louis
The Wildwood Hotel
Ballroom

The Wildwood Hotel

3.5 star property
9.2 out of 10, Wonderful, (1559)
"Great place to stay."
The price is ₩122,499
₩148,128 total
includes taxes & fees
Sep 1 - Sep 2
The Wildwood Hotel
Courtyard by Marriott St. Louis Chesterfield
BBQ/picnic area

Courtyard by Marriott St. Louis Chesterfield

3.0 star property
9.0 out of 10, Wonderful, (544)
"Close to several food choices "
The price is ₩146,388
₩170,341 total
includes taxes & fees
Aug 24 - Aug 25
Courtyard by Marriott St. Louis Chesterfield
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Southhampton

Find the best Southhampton areas and neighborhoods for the activities you enjoy most.
Meeting of the Waters Fountain showing a statue or sculpture and a fountain
Downtown St. Louis map

Downtown St. Louis

3 out of top 10 points of interest in this area

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Clayton map

Clayton

1 out of top 10 points of interest in this area

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Central West End
Central West End map

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Creve Coeur map

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

St. Louis which includes interior views
Downtown West map

Downtown West

3 out of top 10 points of interest in this area

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

Top Southhampton Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent
"Excellent hotel in a great location. Right near the Arch. 10 minute (at worst) walk to the stsdium. Staff was super friendly and quite helpful. We really enjoyed happy hour. Good snack food. The afternoon snacks were outstanding. "
Jan 1-night trip
Posted 13 hours ago
Drury Plaza Hotel St. Louis at the Arch

Frequently asked questions

What is Southhampton like?

Travelers to the Southhampton neighborhood in St. Louis will be sure to enjoy their stay.

How many hotels will I find in the Southhampton area?

If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 22 Southhampton hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in Southhampton, will I receive a refund?

Yes! The majority of hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then filter by "fully refundable" to view the best deals in Southhampton.

Where can I learn more about changing or cancelling my trip to Southhampton?

To find more details about rescheduling or cancelling your trip to Southhampton, click here.

What can I see and do in this St. Louis neighborhood?

A few places to visit in the area around Southhampton include Miniature Museum of Greater St. Louis, Lindenwood Park, and River des Peres Greenway Trailhead. When you're sightseeing in St. Louis, Tower Grove Tennis Center and George Washington Carver Garden are also worth a stop.