St. Charles County Vacations & Trips

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Top destinations in St. Charles County

Are you in Missouri Wine country and all of the local wineries are closed? You don't need to drive far for some good food and good country music! Defiance Roadhouse sits right on highway 94 and offers a plethora of food to fit any fancy!
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Defiance

Defiance

St. Charles County Hotel Deals

Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
4.5 out of 5
1 Ameristar Blvd, St. Charles, MO
Fully refundableReserve now, pay when you stay
The price is ₩228,921 per night from Jun 30 to Jul 1
₩228,921
₩289,998 total
Jun 30 - Jul 1
includes taxes & fees
8.2/10 Very Good! (1,001 reviews)
"Staff was very accommodating"

Reviewed on Jun 23, 2025

Ameristar Casino Resort and Spa
Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch
4 out of 5
315 Chestnut St, St. Louis, MO
The price is ₩161,967 per night from Jun 29 to Jun 30
₩161,967
₩191,006 total
Jun 29 - Jun 30
includes taxes & fees
8.4/10 Very Good! (3,789 reviews)
"Our room was nice & clean. Staff was amazing... very helpful, friendly & offered my grandson a voucher for a free bat at the Cardinals game... made gis day! Our only issue was the traffic noise from the highway."

Reviewed on Jun 25, 2025

Hyatt Regency St. Louis at The Arch
Drury Plaza Hotel St. Louis at the Arch
Drury Plaza Hotel St. Louis at the Arch
3 out of 5
2 South 4th Street, St. Louis, MO
The price is ₩162,390 per night from Jul 13 to Jul 14
₩162,390
₩189,881 total
Jul 13 - Jul 14
includes taxes & fees
9.4/10 Exceptional! (2,778 reviews)
"Liked that its close to Busch stadium. And that it has a nice breakfast buffet. I think the kickback time should be 330 to 530"

Reviewed on Jun 26, 2025

Drury Plaza Hotel St. Louis at the Arch
See all 2,350 properties in St. Charles County
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a St. Charles County vacation package cost?
We make it easy to travel somewhere new, with St. Charles County vacation packages starting from as low as . You'll have the flexibility to bundle your favorite airlines, hotels and car rental. For the ultimate getaway, why not add a couple of tours and activities to your itinerary?
How do I get a cheap travel package to St. Charles County?
Crafting your own St. Charles County vacation package with Expedia is one of the easiest ways to save. We have more than 550 airlines and 1,000,000 properties worldwide. With such an extensive range to pick from, you'll have no trouble putting together your next dream vacation.
What are the top hotels in St. Charles County?
For hotels in Defiance with comfy beds and friendly service, check out Research Park Inn St Louis West -- Chesterfield and Embassy Suites by Hilton St. Louis St. Charles. If you plan to visit Foristell as well, you'll get a solid night's sleep at Best Western Plus The Charles Hotel or Drury Plaza Hotel St. Louis St. Charles.
How far in advance should I book my St. Charles County vacation?
Get rewarded with the widest variety at the lowest prices by booking your vacation to St. Charles County early. Airlines typically release tickets anywhere up to a year in advance, so start locking things in ASAP. That being said, Expedia is constantly working to give you the best bargains around, so it's always a good time to book your dream vacation!
What does an Expedia St. Charles County travel package include?
From flights and hotels to rental cars, Expedia can help you shape a St. Charles County package that works for you. Heading off for a week or two? Check out a rental car, flight and hotel bundle. If you're taking a quick break, a flight and hotel deal could be what you're after. Tours and activities can be added after you've booked. Our vacation packages make it a cinch to plan and save.
What should I know before booking a St. Charles County travel package?
A package can be more affordable than separately booking all you need for your trip. For example, combine your hotels, flights and rental cars and score impressive savings. No matter your vacation goals, you're bound to find a package that matches your budget.
Can I choose my airline with a St. Charles County Expedia vacation package?
Yes --- and it's easy too. Expedia has access to more than 550 partner airlines throughout the world. Our packages give you the freedom to pick from available flight, hotel or activity options that fit your needs.
If I'm not able to travel, can I cancel my St. Charles County vacation package?
It's hard to predict what the future holds, so it's comforting to know that you can cancel or change your St. Charles County vacation package. If you made your booking in the last 24 hours, you may be entitled to a refund. If it's an older booking, your hotel, airline or car rental company may charge a fee. Visit our Customer Service Portal for further details.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.