Skip to main content

Hampton Inn & Suites St. Louis/South I-55

2.5 star property
Travelers start their day with a hearty breakfast buffet at this convenient hotel, perfectly positioned for exploring the attractions of St. Louis

Choose dates to view prices

Hampton Inn & Suites St. Louis/South I-55 combines comfort with practicality in an ideal location. Guests enjoy a satisfying breakfast buffet each morning, can relax beside the welcoming lobby fireplace, or take advantage of the indoor swimming pool during their stay.

Reviews

9.6 out of 10
Exceptional

Popular amenities

  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
The current price is ₩186,345
₩214,271 total
includes taxes & fees
May 31 - Jun 1

Room options

Available filters for rooms
Showing 14 of 14 rooms

View all photos for Room

In-room safe, blackout drapes, iron/ironing board

Room

9.8 out of 10
Exceptional
(41 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

View all photos for Room

In-room safe, blackout drapes, iron/ironing board

Room

9.6 out of 10
Exceptional
(15 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Room

In-room safe, blackout drapes, iron/ironing board

Room

9.6 out of 10
Exceptional
(4 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed
  • Free WiFi

View all photos for Room

In-room safe, blackout drapes, iron/ironing board

Room

10.0 out of 10
Exceptional
(2 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed
  • Free WiFi

View all photos for Two Queen Beds, Non-Smoking, Accessible

Two Queen Beds, Non-Smoking, Accessible | In-room safe, blackout drapes, iron/ironing board

Two Queen Beds, Non-Smoking, Accessible

9.8 out of 10
Exceptional
(27 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

View all photos for One King Bed, Non-Smoking, Accessible

One King Bed, Non-Smoking, Accessible | In-room safe, blackout drapes, iron/ironing board

One King Bed, Non-Smoking, Accessible

9.8 out of 10
Exceptional
(21 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Studio, Accessible, Non Smoking

Studio, Accessible, Non Smoking | In-room safe, blackout drapes, iron/ironing board

Studio, Accessible, Non Smoking

8.0 out of 10
Very good
(6 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed
  • Free WiFi

King Room-Non-Smoking

  • Sleeps 2
  • Free WiFi

Guest Room With 1 King Bed And Mobility/Hearing Accessible With Tub-Nonsmoking

  • Sleeps 2
  • Free WiFi

King Studio Suite With Whirlpool-Non-Smoking

  • Sleeps 3
  • Free WiFi

2 Queen Beds Room, Non-Smoking

  • Sleeps 4
  • Free WiFi

Mobility Hearing Accessible King Studio with Roll in Shower

  • Sleeps 3
  • Free WiFi

2 Queens Mobility/Hearing Access Tub Nosmok

  • Sleeps 4
  • Free WiFi

King Studio Suite-Non-Smoking

  • Sleeps 3
  • Free WiFi

You may also like

Ad

Holiday Inn Express & Suites St. Louis West - Fenton by IHG

Fenton
  • Pool
  • Breakfast included
  • Pet friendly
  • Free WiFi
8.8 out of 10, Excellent, 1,001 reviews
The price is ₩157,433
₩181,816 total
includes taxes & fees
May 17 - May 18
Holiday Inn Express & Suites St. Louis West - Fenton by IHG
Mod logo
Sign in to view eligible discounts and perks. More rewards for more adventures!
Sign inSign up, it's free

About the neighborhood

St. Louis is home to Hampton Inn & Suites St. Louis/South I-55. St. Louis Zoo is a popular attraction and the area's natural beauty can be seen at Mississippi River and Forest Park. BounceU of St. Louis and Grant's Farm are also worth visiting. Visit our St. Louis travel guide
Map
4200 Midamerica Lane, St. Louis, MO, 63129

What's nearby

  • Busch Stadium
    Busch Stadium
    16 min drive - 28.2 km
  • Gateway Arch
    Gateway Arch
    17 min drive - 28.9 km
  • Union Station, St. Louis, MO
    St. Louis Union Station
    18 min drive - 28.3 km
  • Forest Park
    Forest Park
    20 min drive - 32.8 km
  • St. Louis Zoo
    St. Louis Zoo
    23 min drive - 35.7 km

Getting around

  • Kirkwood Station
    14 min drive
  • St. Louis Lambert Intl. Airport (STL)
    31 min drive

Restaurants

  • McDonald's
    3 min drive
  • Burger King
    10 min walk
  • Popeyes Louisiana Kitchen
    3 min walk
  • Hardee's / Red Burrito
    10 min walk
  • Rich & Charlie's Italian Restaurant
    3 min drive

About this property

Hampton Inn & Suites St. Louis/South I-55

Hotel near Mississippi River
At Hampton Inn & Suites St. Louis/South I-55, you can look forward to a free breakfast buffet, a grocery/convenience store, and dry cleaning/laundry services. Free in-room WiFi is available to all guests, along with a fireplace in the lobby and a gym.
Additional perks include:
  • An indoor pool
  • Free self parking
  • Express check-in, ATM/banking services, and a banquet hall
  • Laundry services, 1 meeting room, and a 24-hour front desk
  • Guest reviews speak highly of the breakfast and helpful staff
Room features
All 92 rooms offer comforts such as air conditioning, as well as perks like free WiFi and safes. Guest reviews speak positively of the clean rooms at the property.
More conveniences in all rooms include:
  • Bathrooms with free toiletries and hair dryers
  • 37-inch LCD TVs with cable channels
  • Wardrobes/closets, refrigerators, and microwaves

Similar properties

Property amenity
Holiday Inn Express & Suites St. Louis South - I-55 by IHG
St. Louis
  • Pool
  • Breakfast included
  • Parking included
  • Free WiFi
9.6 out of 10, Exceptional, 1,004 reviews
The price is ₩173,618
₩199,639 total
includes taxes & fees
May 10 - May 11
Holiday Inn Express & Suites St. Louis South - I-55 by IHG
Compare similar properties

Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM
  • Coffee and tea in common areas

Things to do

  • Gym
  • Indoor pool
  • TV in common areas

Family friendly

  • Grocery/convenience store
  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • Indoor pool
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • ATM
  • Free newspapers in lobby
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • 753 square feet of conference space
  • Business center
  • Computer station
  • Meeting room

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Elevator
  • Phone accessibility kit
  • Stair-free path to entrance
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible van parking

More

  • 1 building
  • 5 floors
  • Banquet hall
  • Built in 2010
  • Fireplace in lobby
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Towels provided

Entertainment

  • 37-inch LCD TV with cable channels
  • Pay movies

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Free local calls
  • Free weekday newspapers
  • Iron/ironing board
  • Phone
  • Safe

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: midnight
Contactless check-in available
Express check-in available

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 75 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Welcoming dogs and cats only
2 total pets
Pets cannot be left unattended

Children and extra beds

Children are welcome
Rollaway/extra beds are not available
Free cribs are available on request at the property

Property payment types

Important information

Optional extras

  • Pet fee: USD 75 per accommodation, per stay
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards and debit cards; cash is not accepted
This property reserves the right to pre-authorize the guest's credit card prior to arrival.

We should mention

Pool access available from 8 AM to 10 PM
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
Children under 13 years old are not allowed in the swimming pool or fitness facility without adult supervision
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Hampton Inn I-55
Hampton Inn I-55 St.Louis
Hampton Inn South St.Louis
Hampton Inn St.Louis I-55
Hampton Inn St.Louis South
Hampton Inn St.Louis South I-55
Hampton Inn St.Louis South I-55 Hotel
Hampton Inn St.Louis South I-55 Hotel St. Louis
Hampton Inn St.Louis South I-55 St. Louis
St.Louis South
Hampton Inn Suites St.Louis South at I 55

Frequently asked questions

Does Hampton Inn & Suites St. Louis/South I-55 have a pool?

Yes, this property has an indoor pool. Pool access is from 8 AM–10 PM.

How much does it cost to stay at Hampton Inn & Suites St. Louis/South I-55?

As of May 4, 2026, prices found for a 1-night stay for 2 adults at Hampton Inn & Suites St. Louis/South I-55 on May 31, 2026 start from ₩186,345, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is Hampton Inn & Suites St. Louis/South I-55 pet-friendly?

Yes, Hampton Inn & Suites St. Louis/South I-55 allows cats and dogs (limit 2 total). There's a fee of USD 75 per accommodation, per stay. Service animals are exempt from fees.

How much is parking?

Self parking is free at this property.

What time is check-in at Hampton Inn & Suites St. Louis/South I-55?

Check-in start time: 3 PM; Check-in end time: midnight.

What time is check-out at Hampton Inn & Suites St. Louis/South I-55?

Check-out is at 11 AM.

Where is Hampton Inn & Suites St. Louis/South I-55 located?

Situated in St. Louis, this hotel is 0.3 mi (0.6 km) from Barnes Jewish South Campus and within 3 mi (5 km) of BounceU of St. Louis and St Anthony's. Suson Park and Kindred Hospital St. Louis South are also within 3 mi (5 km).

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

Have a question?

AI iconBeta

Get instant answers with AI powered search of property information and reviews.

Reviews

Hampton Inn & Suites St. Louis/South I-55 Reviews

9.6

Exceptional

9.8

Cleanliness

9.2

Location

9.8

Staff & service

9.6

Property conditions & facilities
Rating 10 - Excellent. 821 out of 1002 reviews
Rating 8 - Good. 129 out of 1002 reviews
Rating 6 - Okay. 27 out of 1002 reviews
Rating 4 - Poor. 5 out of 1002 reviews
Rating 2 - Terrible. 20 out of 1002 reviews

Reviews

Verified

10/10 Excellent

Jenny

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff was friendly, breakfast was delicious. I really enjoyed my stay
Stayed 1 night in Apr 2026
Verified

10/10 Excellent

Kim

Liked: Cleanliness, staff & service, property conditions & facilities
Parking felt safe , nice staff
Stayed 1 night in Apr 2026
Verified

10/10 Excellent

winnie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean room and good breakfast. We love stay in this hotel.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

mary

Liked: Cleanliness, staff & service, property conditions & facilities
Room was clean and comfortable Staff professional friendly and helpful Breakfast was great! Several choices.
Stayed 5 nights in Apr 2026
Verified

10/10 Excellent

Jennifer

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff and room was GREAT!!! Parking was great!! Room was clean and well stocked. Breakfast was good as always. Nice comfortable environment that makes you feel home away from home. We will be returning.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Kathleen

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This was a great stay for us! Friendly desk and breakfast staff. Clean throughout the property! Very comfortable.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Charles

Liked: Cleanliness, amenities, property conditions & facilities
Everything was just about needed to be friendly staff. Would recommend !!
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Josi

Liked: Cleanliness, staff & service, amenities
Fast check in. Nice staff. Clean and quiet room!!
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Jerry

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Really nice rooms and staff , good breakfast!
Stayed 1 night in Sep 2025
Verified

10/10 Excellent

Miliska

Liked: Cleanliness, staff & service, amenities
The room was clean, modern, and pleasant. Staff members were welcoming, respectful, positive, and helpful.
Stayed 1 night in Jan 2026
Verified

8/10 Good

Jeffrey

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
The breakfast was good. The staff was friendly and they allowed us to check out late.
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Manivannan

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Parking is Safe, Cleanliness is Good. Hospitality is Appreciable.
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Amy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff was nice and friendly. Room was nice and clean.
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Renee

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Very clean, modern rooms with a welcoming staff.
Stayed 1 night in Oct 2025
Verified

10/10 Excellent

Eric

Liked: Cleanliness, amenities, property conditions & facilities
Big and comfortable rooms with excellent services
Stayed 1 night in Oct 2025
Verified

10/10 Excellent

Jane

Liked: Cleanliness, amenities, property conditions & facilities
The staff was wonderful and the location perfect!
Stayed 2 nights in Jun 2025
Verified

10/10 Excellent

Michael

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved the unique decor, the conference room, and the well attended bathrooms. Super helpful staff.
Stayed 1 night in Oct 2025
Verified

10/10 Excellent

SHELLY

Liked: Cleanliness, staff & service, amenities
Clean room, good breakfast. Nice, safe area. But the staff was the best I have encountered in a long time. From check in, check out to the breakfast staff. I cannot say enough. We stayed 12/6/25 - one night and I would come back in a heartbeat.
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Brittany

Liked: Cleanliness, staff & service, property conditions & facilities
Everything was great! Clean, comfortable and breakfast was fantastic!
Stayed 1 night in Jul 2025
Verified

10/10 Excellent

Angie

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great stay

Convenient, clean and would stay there again if I needed to
Stayed 2 nights in Feb 2025
Verified

10/10 Excellent

Sandro

Liked: Cleanliness, staff & service, property conditions & facilities
Great experience for a weekend in St Louis, the hotel convenience is great, staff very polite in the breakfast and all match with the content in the site, recommend!
Stayed 2 nights in Jun 2025
Verified

10/10 Excellent

John

The best hotel staff I’ve ever encountered.
Stayed 2 nights in Jul 2025
Verified

10/10 Excellent

Shannon

Liked: Cleanliness, staff & service, property conditions & facilities
Big rooms and nice breakfast buffet
Stayed 1 night in Dec 2024
Verified

8/10 Good

Michael

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
A good, simple, comfortable stay.
Stayed 4 nights in Dec 2024
Verified

10/10 Excellent

Michael

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Quick trip

Needed a hotel for an overnight. This was a great hotel. Very friendly staff and very clean. Good hot breakfast served. Would definitely stay there again if in the area.
Stayed 1 night in May 2025