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Top Honeymoon Eastern Piedmont Hotels

The Mayton

301 S Academy St Cary NC

37 min drive from Duke University

Book a stay at this boutique hotel in Cary. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular ...

9.4/10 Exceptional! (730 reviews)

Great vibe — elegant and cozy (but not stuffy). The hotel location drew us and did not disappoint. The Downtown Cary Park is easily accessible! Also walked to restaurants a few blocks away.

Reviewed on Jan 8, 2026

The Umstead Hotel and Spa

100 Woodland Pond Dr Cary NC

29 min drive from Duke University

Book a stay at this luxury resort in Cary. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions ...

9.4/10 Exceptional! (728 reviews)

The bed was an absolute dream. The service from every staff member was exceptional. The amenities were fantastic. This hotel is everything you have read and heard about but better.

Reviewed on Jan 23, 2026

21c Museum Hotel Durham

111 North Corcoran Street Durham NC

10 min walk from Duke University

Stay at this hotel in Durham. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff in our reviews. Popular attractions ...

8.2/10 Very Good! (1,000 reviews)

Aside from the heater barely working in the rooms in the middle of winter, it was a nice stay. We moved once and both rooms on both floors had poor heating it was uncomfortable. However, the staff were always professional and friendly. The 4 stars are for them

Reviewed on Jan 30, 2026

See all 4,751 properties in Eastern Piedmont

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.